The total number of records retrieved from this search are 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2132	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2133	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2134	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2135	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2136	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2137	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2138	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	BALB/c mice xenograft for Huh7 cell line (5.0E+6 × 10⁶ pfu)	2.0E+9 pfu	NA	Significant reduction in tumor volume below 100mm and increase in median survival time after 57 days	Intratumoral	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2528	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	0.1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2529	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2530	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	35% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2531	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	0.1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2532	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2533	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	60% cellsa are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2534	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	0.1 MOI	100% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2535	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	1 MOI	90% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2536	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	30% cells are viable	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2537	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	90% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2538	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2539	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	70% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2540	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	MTT assay	10 MOI	60% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2541	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	90% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2542	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2543	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	70% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2544	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	MTT assay	10 MOI	60% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2545	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	100% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2546	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	80% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2547	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	40% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2548	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	PLC	NA	NA	MTT assay	10 MOI	10% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2549	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	90% cells viable after day 1	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2550	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	70% cells viable after day 2	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2551	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	50% cells viable after day 3	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2552	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	MTT assay	10 MOI	30% cells viable after day 4	No	No	NA	No response	NA	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2553	Adenovirus	AD55-Apoptin	DNA	Adenoviridae	Deletion of E1B gene and insertion of Apoptin gene	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for Huh7 cell line (1.0E+7)	3.0E+8 pfu	NA	Reduction in tumor volume below 425mm after 16 days	Intratumoral	Induction of apotosis as measured by TUNEL assay	NA	NA	22321574
OV_2554	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	90.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2555	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	70.3% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2556	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	56.2% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2557	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	25.3% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2558	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	88.3% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2559	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	64% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2560	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	35.2% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2561	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	1000 cells	NA	MTT assay	10 MOI	17.7% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2562	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	88.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2563	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	72.3% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2564	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	58% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2565	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	28% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2566	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	84.3% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2567	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	66.2% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2568	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	54.5% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2569	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	MHCC97L	1000 cells	NA	MTT assay	10 MOI	24% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2570	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2571	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	72.5% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2572	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	50.2% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2573	Adenovirus	SG600-IL-24	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	28.2% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2574	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	87.2% cell survival after 24 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2575	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	68% cell survival after 48 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2576	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	45% cell survival after 72 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2577	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	1000 cells	NA	MTT assay	10 MOI	25% cell survival after 96 hours	No	No	NA	No response	NA	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2578	Adenovirus	SG600-IL-24+IFN	DNA	Adenoviridae	Deletion of E1B gene and insertion of IL-24 gene and addition of IN	Yes	No	Virus expressing IL-24 gene and IFN gene	ATCC	Human hepatocellular carcinoma cell line	HCCLM3	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for HCCLM3 cell line	2.0E+8 pfu	NA	Significant reduction in tumor volume from the onset of tretament and till the end of 42 days and increase in median survival time	Intratumoral	Combined therapy increases STAT1, SOCS1 and apoptosis	Combined therapy decreases expression of MMP-2, XIAP,OPN and VEGF	NA	22569271
OV_2665	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2666	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	100% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2667	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	100% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2668	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	100% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2669	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2670	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	90% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2671	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	80% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2672	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	60% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2673	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2674	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2675	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	70% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2676	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	50% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2677	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2678	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	100% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2679	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	90% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2680	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.01 MOI	80% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2681	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2682	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	90% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2683	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	90% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2684	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	0.1 MOI	70% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2685	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2686	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2687	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	70% cell survival after 72 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2688	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	Huh-6	2.0E+5 cells per well	NA	Cell proliferation assay kit	1 MOI	50% cell survival after 96 hours	No	No	NA	No response	NA	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2689	Measles virus	MV-Edm	RNA	Paramyxoviridae	Insertion of human CEA gene upstream of MV N gene	Yes	No	No	ATCC	Human hepatoblastoma cell line	HepG2	NA	NA	NA	NA	NA	Nude mice xenograft for Hep2G (5.0E+6 cell)	1.0E+7 TCID50	NA	Reduction in tumor volume to 300mm after 37 days as compared to control 550mm and increase in survival time above 120 days as compared to control 30 days	Intratumoral	Induction of apoptosis in cancer	Increase expression of CD46	NA	23009685
OV_2690	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	85% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2691	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2692	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2693	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	BEL-7404	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	50% cell viability after 96 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2694	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2695	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2696	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2697	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 96 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2698	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	85% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2699	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2700	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2701	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 96 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2702	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	70% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2703	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2704	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	Shanghai cell collection	Human hepatocellular carcinoma cell line	Huh-7	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	20% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2705	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	23028626
OV_2706	Adenovirus	AdCN205-IL12	DNA	Adenoviridae	None	No	Virus in combination with CIK	Virus expressing IL-12 gene	ATCC	Human hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	Spectrophotometer	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	23028626