| Primary information |
|---|
| OV_ID | OV_2682 |
| Virus Name | Measles virus |
| Strain | MV-Edm |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | Insertion of human CEA gene upstream of MV N gene |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human hepatoblastoma cell line |
| Cell line | Huh-6 |
| Concentration of cell line | 2 |
| In-vitro toxicity | NA |
| Assay | Cell proliferation assay kit |
| In-vitro virus concentration | 0.1 MOI |
| In-vitro result | 90% cell survival after 48 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Induction of apoptosis in cancer |
| Immunogenic effect | Increase expression of CD46 |
| Clinical trial | NA |
| PMID | 23009685 |