Detailed description page of Selected OV_ID


OV_2678 details
Primary information
OV_IDOV_2678
Virus Name Measles virus
StrainMV-Edm
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeInsertion of human CEA gene upstream of MV N gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman hepatoblastoma cell line
Cell lineHuh-6
Concentration of cell line2
In-vitro toxicityNA
AssayCell proliferation assay kit
In-vitro virus concentration0.01 MOI
In-vitro result100% cell survival after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis in cancer
Immunogenic effectIncrease expression of CD46
Clinical trialNA
PMID23009685