The total number record retrieved from this search are 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4461	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN465	4000 to 5000 cells per well	NA	MTS assay	0.33 MOI	20% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4462	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN475	4000 to 5000 cells per well	NA	MTS assay	0.33 MOI	20% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4463	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN298	4000 to 5000 cells per well	NA	MTS assay	0.33 MOI	50% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4464	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN1	4000 to 5000 cells per well	NA	MTS assay	0.33 MOI	10% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4465	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN465	4000 to 5000 cells per well	NA	MTS assay	1 MOI	15% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4466	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN475	4000 to 5000 cells per well	NA	MTS assay	1 MOI	15% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4467	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN298	4000 to 5000 cells per well	NA	MTS assay	1 MOI	30% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4468	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN1	4000 to 5000 cells per well	NA	MTS assay	1 MOI	5% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4469	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN465	4000 to 5000 cells per well	NA	MTS assay	3 MOI	10% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4470	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN475	4000 to 5000 cells per well	NA	MTS assay	3 MOI	12% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4471	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN298	4000 to 5000 cells per well	NA	MTS assay	3 MOI	25% cell viablity after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4472	Herpes simplex virus	G47-delta-mCherry	DNA	Herpesviridae	Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6	Yes	No	No	Human patient	malignant leningioma	MN1	4000 to 5000 cells per well	NA	MTS assay	3 MOI	100% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	26951380
OV_4509	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	100% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4510	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.001mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	75% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4511	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.0025mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	75% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4512	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.005mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	62% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4513	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	90% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4514	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.001mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	70% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4515	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.0025mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	70% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4516	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.005mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	70% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4517	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4518	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.001mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	35% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4519	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.0025mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	30% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4520	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.005mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	35% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4521	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	18% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4522	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.001mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	15% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4523	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.0025mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	15% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4524	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.005mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	15% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4525	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	100% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4526	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	90% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4527	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	80% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4528	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	80% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4529	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	70% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4530	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	62% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4531	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4532	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4533	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4534	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	20% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4535	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	20% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4536	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	20% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4981	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	78% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4982	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0026 mg/ml + cisplatin 0.0625	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	35% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4983	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0026 mg/ml + carboplatin 0.0625	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	22% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4984	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	90% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4985	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0026 mg/ml + cisplatin 0.0625	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4986	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0026 mg/ml + carboplatin 0.0625	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	72% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4987	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	90% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4988	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0006 mg/ml + cisplatin 0.0019	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	60% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4989	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0006 mg/ml + carboplatin 0.083	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4990	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	1 VP per cell	100% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4991	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	80% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4992	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	100 VP per cell	60% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4993	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human malignant biphasic mesothelioma cell line	MTSO-211H	1.0E+4 cells per well	NA	MTS assay	1000 VP per cell	20% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4994	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	1 VP per cell	100% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4995	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	90% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4996	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	100 VP per cell	40% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4997	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	H226	1.0E+4 cells per well	NA	MTS assay	1000 VP per cell	20% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4998	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	1 VP per cell	100% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4999	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	80% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_5000	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	100 VP per cell	40% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_5001	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	1000 VP per cell	20% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_5092	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	70% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5093	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	50% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5094	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	20% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5095	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5096	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	70% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5097	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5098	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	40% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5099	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	HS294T	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5100	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5101	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	30% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5102	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5103	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5104	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	80% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5105	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	30% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5106	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5107	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	A2058	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5108	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5109	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	80% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5110	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	50% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5111	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5112	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5113	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5114	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5115	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human lung cancer cell line	A549	1.0E+4 cells per well	NA	MTS assay	1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5116	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	60% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5117	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	40% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5118	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	10% cell viability	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5119	Vaccinia virus	vvdd-tdTomato-hDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of human DAI	Yes	No	Virus expressing human DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5120	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.001 MOI	90% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5121	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.01 MOI	70% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5122	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	0.1 MOI	20% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5123	Vaccinia virus	vvdd-tdTomato-mDAI	DNA	Poxviridae	Deletion of tk gene and vaccinia growth gene and addition of murine DAI	Yes	No	Virus expressing murine DAI gene	ATCC	Human melanoma cell line	SK-MEL-2	1.0E+4 cells per well	NA	MTS assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	Induction of Immunogenic gene such as T cell activation	NA	27626058
OV_5126	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5127	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.01 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5128	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.1 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5129	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	1 MOI	42% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5130	Semliki forest virus	wild type SFV4	RNA	Alphaviridae	None	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	10 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5131	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.001 MOI	100% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889
OV_5132	Semliki forest virus	SFVmiRT	RNA	Alphaviridae	Insertional mutagenesis at 3UTr for miR124, 125 and 134	Yes	No	No	NA	Murine neuroblastoma cell line	NXS2	20000 cells per well	NA	MTS assay	0.01 MOI	82% cell viability after 72 hours	No	No	NA	No response	NA	NA	Induce production of IFN gamma	NA	27637889