Primary information |
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OV_ID | OV_4471 |
Virus Name | Herpes simplex virus |
Strain | G47-delta-mCherry |
Virus type | DNA |
Virus family | Herpesviridae |
Modification in virus genome | Deletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6 |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | Human patient |
Origin of cell line | malignant leningioma |
Cell line | MN298 |
Concentration of cell line | 4000 |
In-vitro toxicity | NA |
Assay | MTS assay |
In-vitro virus concentration | 3 MOI |
In-vitro result | 25% cell viablity after 96 hours |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 26951380 |