| Primary information |
|---|
| OV_ID | OV_5104 |
| Virus Name | Vaccinia virus |
| Strain | vvdd-tdTomato-mDAI |
| Virus type | DNA |
| Virus family | Poxviridae |
| Modification in virus genome | Deletion of tk gene and vaccinia growth gene and addition of murine DAI |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | Virus expressing murine DAI gene |
| Source of cell line | ATCC |
| Origin of cell line | Human melanoma cell line |
| Cell line | A2058 |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | MTS assay |
| In-vitro virus concentration | 0.001 MOI |
| In-vitro result | 80% cell viability |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | Induction of Immunogenic gene such as T cell activation |
| Clinical trial | NA |
| PMID | 27626058 |