| Primary information |
|---|
| OV_ID | OV_4995 |
| Virus Name | Adenovirus |
| Strain | ONCOS-102 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | Virus expressing human GM-CSF gene |
| Source of cell line | DSMZ Germany |
| Origin of cell line | Human epitheliod mesothelioma |
| Cell line | H226 |
| Concentration of cell line | 1 |
| In-vitro toxicity | NA |
| Assay | MTS assay |
| In-vitro virus concentration | 10 VP per cell |
| In-vitro result | 90% cell viability after 3 days |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus induce apoptosis |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 27287512 |