Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interleukin-4 inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IL4pred server. The last column display the score of peptides from IL4pred server.


Total number of predicted 9mer peptides are 171460 (corresponding to browse type th2)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IL4 prediction score
VIR07320731793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]106IYLFKNNTD DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0423, DRB1_1304, DRB1_1501, DRB1_1506 9 0.30
VIR07320831793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]107YLFKNNTDS DRB1_0401, DRB1_0402, DRB1_0405, DRB1_0408, DRB1_0421, DRB1_0423, DRB1_0426, DRB1_0801, DRB1_0802, DRB1_0813, DRB1_0817, DRB1_1114, DRB1_1120, DRB1_1302, DRB1_1323 15 0.30
VIR07320931793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]108LFKNNTDSA DRB1_0401, DRB1_0421, DRB1_0426 3 0.99
VIR07322131793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]120YGCHENYLI DRB1_0402, DRB1_0421, DRB1_0701, DRB1_0703, DRB1_1502 5 0.27
VIR07322731793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]126YLIVRAGEF DRB1_0101, DRB1_0309, DRB1_0701, DRB1_0703, DRB1_0801, DRB1_0802, DRB1_1101, DRB1_1128, DRB1_1305, DRB1_1307, DRB1_1321, DRB5_0101, DRB5_0105 13 0.44
VIR07322831793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]127LIVRAGEFS DRB1_0813 1 0.44
VIR07322931793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]128IVRAGEFSR DRB5_0101, DRB5_0105 2 0.47
VIR07323531793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]134FSRISDVLL DRB1_0703 1 0.28
VIR07324631793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]145LVTRQLICG DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1506 7 0.26
VIR07324731793280 NP 855773.1 hypotheticalproteinMb2124c[MycobacteriumbovisAF2122/97]146VTRQLICGA DRB1_1102, DRB1_1121, DRB1_1322 3 0.23
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