Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interleukin-4 inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IL4pred server. The last column display the score of peptides from IL4pred server.


Total number of predicted 9mer peptides are 171460 (corresponding to browse type th2)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IL4 prediction score
VIR06197631792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1631VLNSVTGAA DRB1_0301, DRB1_0305, DRB1_0401, DRB1_0426, DRB1_1107 5 0.27
VIR06199131792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1646LLALGGRFI DRB1_0101, DRB1_0102, DRB5_0101, DRB5_0105 4 0.23
VIR06199831792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1653FIEIGKRDI DRB1_0703, DRB1_1101, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1323 9 0.29
VIR06200631792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1661IYSNTRLEL DRB1_1101, DRB1_1104, DRB1_1106, DRB1_1128, DRB1_1304, DRB1_1305, DRB1_1311, DRB1_1321, DRB1_1501, DRB1_1502, DRB1_1506 11 0.40
VIR06200731792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1662YSNTRLELL DRB1_0701, DRB1_0703 2 0.30
VIR06202831792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1683LGLMSVSHP DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0423, DRB1_0813 6 0.23
VIR06203931792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1694VRELLSTVY DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0423 5 0.25
VIR06204331792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1698LSTVYRLTV DRB1_1506 1 0.30
VIR06204631792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1701VYRLTVEGV DRB1_0102, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0311, DRB1_0401, DRB1_0404, DRB1_0421, DRB1_0423, DRB1_0426 10 0.29
VIR06204731792713 NP 855206.1 polyketidesynthase[MycobacteriumbovisAF2122/97]1702YRLTVEGVL DRB1_0701, DRB1_0703, DRB5_0101, DRB5_0105 4 0.30
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