Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interleukin-4 inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IL4pred server. The last column display the score of peptides from IL4pred server.


Total number of predicted 9mer peptides are 171460 (corresponding to browse type th2)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IL4 prediction score
VIR040983339633567 YP 004725209.1 biphenyl-2,3-diol1,2-dioxygenaseBPHC(23OHBPoxygenase)[MycobacteriumafricanumGM041182]253LSFYMKTPG DRB1_0813 1 0.23
VIR040985339633567 YP 004725209.1 biphenyl-2,3-diol1,2-dioxygenaseBPHC(23OHBPoxygenase)[MycobacteriumafricanumGM041182]255FYMKTPGGF DRB1_0309, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1120, DRB1_1128, DRB1_1302, DRB1_1305, DRB1_1307, DRB5_0101, DRB5_0105 14 0.21
VIR041009339633567 YP 004725209.1 biphenyl-2,3-diol1,2-dioxygenaseBPHC(23OHBPoxygenase)[MycobacteriumafricanumGM041182]279WIARESTAV DRB1_0813 1 0.26
VIR041010339633567 YP 004725209.1 biphenyl-2,3-diol1,2-dioxygenaseBPHC(23OHBPoxygenase)[MycobacteriumafricanumGM041182]280IARESTAVS DRB1_0401, DRB1_0404, DRB1_0408, DRB1_0421, DRB1_0423, DRB1_0426 6 0.25
VIR041020339633567 YP 004725209.1 biphenyl-2,3-diol1,2-dioxygenaseBPHC(23OHBPoxygenase)[MycobacteriumafricanumGM041182]290WGHDFTVGA DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0408, DRB1_0421, DRB1_0426, DRB1_1107 12 0.28
VIR041049339633613 YP 004725255.1 hypotheticalproteinMAF 36270[MycobacteriumafricanumGM041182]27WTADPIIGV DRB1_0305, DRB1_0309 2 0.32
VIR041111339633613 YP 004725255.1 hypotheticalproteinMAF 36270[MycobacteriumafricanumGM041182]89LSARVAWMS DRB1_0402 1 0.28
VIR041117339633613 YP 004725255.1 hypotheticalproteinMAF 36270[MycobacteriumafricanumGM041182]95WMSESQLAS DRB1_0401, DRB1_0421, DRB1_0426, DRB1_1101 4 0.24
VIR041127339633613 YP 004725255.1 hypotheticalproteinMAF 36270[MycobacteriumafricanumGM041182]105ILVIADLAR DRB5_0101, DRB5_0105 2 0.28
VIR041128339633613 YP 004725255.1 hypotheticalproteinMAF 36270[MycobacteriumafricanumGM041182]106LVIADLARQ DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0423, DRB1_0426, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1107, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB5_0101, DRB5_0105 43 0.29
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