Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interleukin-4 inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IL4pred server. The last column display the score of peptides from IL4pred server.


Total number of predicted 9mer peptides are 171460 (corresponding to browse type th2)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IL4 prediction score
VIR031340339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]2VHATACSEI DRB1_0701, DRB1_0703 2 0.28
VIR031378339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]40IRMMSLVGR DRB1_0101, DRB1_0102, DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0421, DRB1_0423, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1107, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1506, DRB5_0101, DRB5_0105 46 0.26
VIR031380339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]42MMSLVGRWR DRB1_0102, DRB1_1301, DRB1_1327, DRB1_1328, DRB5_0101, DRB5_0105 6 0.28
VIR031381339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]43MSLVGRWRR DRB5_0101, DRB5_0105 2 0.27
VIR031383339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]45LVGRWRRKG DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328 17 0.27
VIR031384339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]46VGRWRRKGI DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328 11 0.28
VIR031387339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]49WRRKGIAVD DRB1_0405, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1307, DRB1_1321, DRB1_1323, DRB1_1327, DRB1_1328 20 0.21
VIR031392339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]54IAVDFATLA DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0311, DRB1_1107 6 0.33
VIR031396339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]58FATLAATPT DRB1_0101, DRB1_0102 2 0.26
VIR031399339632409 YP 004724051.1 phenyloxazolinesynthase[MycobacteriumafricanumGM041182]61LAATPTIEA DRB1_0401, DRB1_0402, DRB1_0426 3 0.58
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