Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last three column present the field related to HLA prediction using CTLpred and nHLApred The second last tells us the HLA alleles to which peptide is binding. The last column counts the number of HLA alleles for that peptide.


Total number of predicted 9mer peptides are 279773 (corresponding to browse type ctl)



ID gene IDProtein DetailPositionSequence (9mer)MHC class I Alleles MHC class I alleles (count) HLA Alleles HLA alleles (count)
VIR018329339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1914AANSWLDTF HLA-B*3501,HLA-B*4403,HLA-B*5801,HLA-B62,MHC-Ld 5 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9
VIR018333339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1918WLDTFTHWR HLA-A1,HLA-A20 Cattle,HLA-A2.1,HLA-A3,HLA-A*3101,HLA-A*3302,HLA-A68.1,HLA-B*51,HLA-B*5401 9 HLA-A1,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 10
VIR018338339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1923THWRRAQDL HLA-B14,HLA-B*3801,HLA-B*3901,HLA-B*3902,MHC-Dd 5 HLA-A2,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 10
VIR018351339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1936IAWGAWGQI HLA-B*2702,HLA-B*51,HLA-B*5101,HLA-B*5102,HLA-B*5103,HLA-B*5201,HLA-B*5301,HLA-B*5401,HLA-B*5801,MHC-Db revised,MHC-Kk 11 HLA-A*1101,HLA-A3,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,HLA-B*2706,Mamu-A*01,HLA-A*6801 13
VIR018357339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1942GQIGRAIAF HLA-A3,HLA-B*2702,HLA-B*2705,HLA-B*3801,HLA-B*3902,HLA-B*4403,HLA-B*5201,HLA-B62,MHC-Ld 9 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01,HLA-B*2703,HLA-B*2704,HLA-A*6802 12
VIR018374339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1959APEEGAYAF HLA-A1,HLA-B*0702,HLA-B*3501,HLA-B*3801,HLA-B*4403,HLA-B*51,HLA-B*5301,HLA-B*5401,HLA-B*5801,HLA-Cw*0401,HLA-Cw*0702,MHC-Ld 12 HLA-A*0203,HLA-A*0301,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01,HLA-B*2704 12
VIR018379339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1964AYAFETLLR HLA-A*1101,HLA-A*3101,HLA-A*3302 3 HLA-A*2402,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 10
VIR018380339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1965YAFETLLRH HLA-B*51,HLA-B*5102,HLA-B*5401 3 HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 9
VIR018390339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1975RAYSGYAPV HLA-A*0201,HLA-A2,HLA-A2.1,HLA-B*0702,HLA-B*2702,HLA-B*2705,HLA-B*5101,HLA-B*5102,HLA-B*5103,HLA-B*5201,HLA-B*5401,HLA-B*5801,HLA-B61,HLA-Cw*0301,MHC-Kb 15 HLA-B*5301,HLA-B*5401,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 11
VIR018391339631598 YP 004723240.1 polyketidesynthase[MycobacteriumafricanumGM041182]1976AYSGYAPVI HLA-A2.1,HLA-A24,HLA-B*5201,HLA-Cw*0401,MHC-Kd,MHC-Kk 6 HLA-A11,HLA-A*2402,HLA-A3,HLA-Cw*0401,H2-Db,H2-Dd,H2-Kb,H2-Kd,H2-Ld,HLA-G,H-2Qa,Mamu-A*01 12
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