Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interleukin-4 inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IL4pred server. The last column display the score of peptides from IL4pred server.


Total number of predicted 9mer peptides are 171460 (corresponding to browse type th2)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IL4 prediction score
VIR021073339631808 YP 004723450.1 phospholipaseC[MycobacteriumafricanumGM041182]451VTGDMTSTF DRB1_0301, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0421, DRB1_1107 8 0.29
VIR021077339631808 YP 004723450.1 phospholipaseC[MycobacteriumafricanumGM041182]455MTSTFNFAV DRB1_0701, DRB1_0703 2 0.30
VIR021117339631808 YP 004723450.1 phospholipaseC[MycobacteriumafricanumGM041182]495INRGIPYRV DRB1_0101, DRB1_0102 2 0.29
VIR021123339631808 YP 004723450.1 phospholipaseC[MycobacteriumafricanumGM041182]501YRVPDPQIM DRB1_0101, DRB1_0305, DRB1_0309, DRB1_0701, DRB1_0703, DRB1_1120, DRB1_1302, DRB5_0101, DRB5_0105 9 0.30
VIR021196339631841 YP 004723483.1 PPEfamilyprotein[MycobacteriumafricanumGM041182]57WVGAASLSM DRB1_0101, DRB1_0102, DRB1_0305, DRB1_0309, DRB1_0401, DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0421, DRB1_0423, DRB1_0426, DRB1_0701, DRB1_0703, DRB1_0801, DRB1_0802, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1104, DRB1_1106, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1323, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1502, DRB1_1506, DRB5_0101, DRB5_0105 39 0.43
VIR021236339631841 YP 004723483.1 PPEfamilyprotein[MycobacteriumafricanumGM041182]97YEAAFVMTV DRB1_0305, DRB1_0309, DRB1_0703, DRB1_1101, DRB1_1128, DRB1_1305, DRB1_1321 7 0.30
VIR021240339631841 YP 004723483.1 PPEfamilyprotein[MycobacteriumafricanumGM041182]101FVMTVPPPV DRB1_0101, DRB1_0102, DRB1_0301, DRB1_0305, DRB1_0309, DRB1_0401, DRB1_0421, DRB1_0426, DRB1_0701, DRB1_0703, DRB1_0802, DRB1_1101, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1302, DRB1_1305, DRB1_1307, DRB1_1321, DRB1_1323, DRB1_1502, DRB5_0101, DRB5_0105 23 0.28
VIR021241339631841 YP 004723483.1 PPEfamilyprotein[MycobacteriumafricanumGM041182]102VMTVPPPVI DRB1_0101, DRB1_0102 2 0.27
VIR021249339631841 YP 004723483.1 PPEfamilyprotein[MycobacteriumafricanumGM041182]110ITANRVLVM DRB1_0421, DRB1_1101, DRB1_1104, DRB1_1106, DRB1_1128, DRB1_1301, DRB1_1305, DRB1_1311, DRB1_1321, DRB1_1327, DRB1_1328 11 0.26
VIR021264339631841 YP 004723483.1 PPEfamilyprotein[MycobacteriumafricanumGM041182]125FFGQNSAAI DRB1_0101, DRB1_0102, DRB1_0401, DRB1_0408, DRB1_0421, DRB1_0426, DRB1_1120, DRB1_1302 8 0.32
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