Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interleukin-4 inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IL4pred server. The last column display the score of peptides from IL4pred server.


Total number of predicted 9mer peptides are 171460 (corresponding to browse type th2)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IL4 prediction score
VIR009857339630827 YP 004722469.1 PhoPfamilytranscriptionalregulator[MycobacteriumafricanumGM041182]236LRGVGYVLR DRB5_0101, DRB5_0105 2 0.29
VIR009888339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]28LPRSVTAFI DRB1_0401, DRB1_0421, DRB1_0426, DRB1_0703 4 0.25
VIR009907339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]47LRTLNRMHE DRB1_0301, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0410, DRB1_0801, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1107, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1506 32 0.26
VIR009913339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]53MHEVIPGAR DRB5_0101, DRB5_0105 2 0.27
VIR009916339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]56VIPGARVEG DRB1_0301, DRB1_0309, DRB1_1107 3 0.28
VIR009926339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]66VLLDDQDIY DRB1_0301, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_1107 7 0.27
VIR009951339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]91FQRPNPFPA DRB1_0305, DRB1_1114, DRB1_1323 3 0.51
VIR009960339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]100MSIRNNVVA DRB1_0402, DRB1_0804 2 0.27
VIR009962339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]102IRNNVVAGL DRB1_0101, DRB1_0102, DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0402, DRB1_0404, DRB1_0410, DRB1_0421, DRB1_0423, DRB1_0426, DRB1_0701, DRB1_0703, DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0806, DRB1_0813, DRB1_0817, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1107, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1128, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1305, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328 44 0.36
VIR009970339630886 YP 004722528.1 phosphateABCtransporterATP-bindingprotein[MycobacteriumafricanumGM041182]110LKLQGVRNR DRB1_0402, DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB5_0101, DRB5_0105 14 0.33
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