Browse Epitopes

This module is created to browse the epitopes predicted from vaccine candidates of all mycobacterial strains. This epitopes were predicted by creating 9mer overlapping peptides from the vaccine candidates from each mycobacterial species. We used a prediction pipeline for predicting the epitopes. Currently, you are browsing B cell epitopes from our compiled results. Here, the first column represent the unique Mtbeveb ID for each peptide sequences. The ID and peptide sequence is hyperlinked to epitope card. The next column contains Gene ID, which is hyperlinked to antigen card. The next column displays the detail of protien from NCBI notation. The fourth column presents the position of the peptide in that protein. This pipeline have the package for predicting linear B cell epitopes using LBtope, promiscous binder of MHC class I (Propred1) and MHC class II (Propred), CTL epitope (CTLpred), interferon-gamma inducing peptides (IFNepitope) and Interleukine 4 inducing peptides (IL4pred). The peptides can sorted at any header. The last five columns present the fields related to MHC class II prediction using Propred followed by prediction of interferon-gamma inducing peptides. The sixth column tells us the MHC class II alleles to which peptide is binding. The seventh column counts the number of MHC class II alleles for that peptide. The eighth column depicts the prediction result of IFNepitope server with ninth column present the alogirithm of IFNepitope program. The last column display the score of peptides from IFNepitope server.


Total number of predicted 9mer peptides are 108182 (corresponding to browse type th1)



ID gene IDProtein DetailPositionSequence (9mer)MHC class II Alleles MHC class II alleles (count) IFN-gamma inducing algorithmIFN-gamma inducing Score
VIR147179378770338 YP 005170071.1 putativetranscriptionalregulatoryprotein,GntRfamily[MycobacteriumbovisBCGstr.Mexico189MTAAAKRPS DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328 11 SVM 0.52
VIR147220378770338 YP 005170071.1 putativetranscriptionalregulatoryprotein,GntRfamily[MycobacteriumbovisBCGstr.Mexico230MAVLVSQAS DRB1_0102, DRB1_0401, DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0421, DRB1_0423, DRB1_0426 10 SVM 0.45
VIR147256378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]34LFQDPTRTY DRB1_0301 1 SVM 0.58
VIR147274378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]52LTLEEAQYA DRB1_0102, DRB1_0401 2 SVM 0.10
VIR147364378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]142IVSIEAFEH DRB1_0101, DRB1_0102, DRB1_0305, DRB1_0402, DRB1_0404, DRB1_0405, DRB1_0408, DRB1_0410, DRB1_0423, DRB1_0701, DRB1_0703, DRB1_0801, DRB1_0804, DRB1_0806, DRB1_1101, DRB1_1102, DRB1_1104, DRB1_1106, DRB1_1107, DRB1_1114, DRB1_1121, DRB1_1304, DRB1_1307, DRB1_1311, DRB1_1321, DRB1_1322, DRB1_1323, DRB1_1506, DRB5_0101, DRB5_0105 30 SVM 0.35
VIR147367378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]145IEAFEHFGH DRB1_1304 1 SVM 0.54
VIR147388378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]166IMPADGRMT DRB1_0102 1 MERCI 0.99
VIR147389378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]167MPADGRMTV DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_1107 8 MERCI 0.99
VIR147459378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]237LRPHYIKTL DRB1_0402, DRB1_0701, DRB1_0703, DRB1_1102, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_1328, DRB1_1501, DRB1_1506 16 SVM 0.14
VIR147490378770397 YP 005170130.1 mmaA4geneproduct[MycobacteriumbovisBCGstr.Mexico]268YNRYMKYLR DRB1_0801, DRB1_0802, DRB1_0804, DRB1_0813, DRB1_0817, DRB1_1114, DRB1_1120, DRB1_1128, DRB1_1302, DRB1_1305, DRB1_1323, DRB1_1502, DRB5_0101, DRB5_0105 14 SVM 0.13
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