Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 68
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1041Trauma induced immunosuppressive glycopeptide (TP)not available0NANANANANANaturalFrom arterial blood of burn or trauma patientneutrophils, T and B LymphocytesThrough stimulation of PGE2 biosynthesis and through a non-cyclooxygenasepathway.In vitroMitomycin-treated stimulator LymphocytesNANAMixed Lymphocyte culture assay and TP-induced PGE2 biosynthesis assayNANA29651051988
1075CKS-17LQNRRGLDLLFLKEGGL17LNoneConjugated to HSA (human serum albumin)NoneLinearSyntheticHomologous region found in the transmembrane envelope proteins of murine, feline, and human retro- viruses HTLV-1 and HTLV-2, and an endogenous C-type human retrovirusLymphocyteInhibits the Proliferation of Purified LymphocytesIn vitroMononuclear Cells, Lymphocytes, Human Neutrophils, Lymphoblastoid cell line-Jurkat cell,10 micromolar in Lymphocyte proliferation assaysNoneLymphocyte Proliferation assayNANA19217611991
1202A1HS1II-Sta-PYVPL8LNoneNoneSta = (3S, 4S) -4- amino-3-hydroxy-6-methyl-heptanoic acid(C8H17NO3)CyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289499 B2010
1203A3HS1IIPPYV-Sta-L8LNoneNoneSta = StatineCyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289498 B2010
1204A4HS1II-Sta-Sta-YVPL8LNoneNoneSta = StatineCyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289497 A2008
1220NACVRGLYIDFRKDLGWK16LNoneNoneNoneLinearSyntheticRetro virusLymphocytes, TGFInhibits cell proliferation, conjugated polypeptide block the binding of TGF-B to its receptorBothMu-I-LvNADBA/IJ male miceThymidine incorporation assay, TGF-fi Radioreceptor Binding Assay, Mice arthritis modelNACoupled to carrier proteins or crosslinked to form polymersCA2057896C2000
1221Aalpha (SEQ ID NO 12)ERHQSACKDSDWPFCSDEDWNYK23LNoneNoneNoneLinearProtein DerivedAlpha chain of the fibrinLymphocyteSuppress increase in inflammatory cells, Aalpha Gly Pro Arg (Pro) - NH 2 acetate (Aalpha derivative) short peptide is equally effective as the long peptides in appropriate continuous addition at inhibiting monocyte migrationIn vivoPBMCNAHU-SCID mouse modelNANANAWO 2002048180 A22002
1222Bbeta (SEQ ID NO 11)DKRKEEAPSLRPAPPPISGGGYR23LNoneNoneNoneLinearProtein DerivedBeta chain of the fibrinLymphocyteInhibition of Lymphocyte migration, blocks the lymphocytic inflammation, Bbeta Gly His Arg Pro-OH acetate (Bbeta derivative) short peptide is equally effective as the long peptides in appropriate continuous addition at inhibiting monocyte migrationIn vivoPBMCNAHU-SCID mouse modelNANANAWO 2002048180 A22002
1375SEQ ID2SCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC34LNoneNoneN-acetylation at position 18LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1376SEQ ID3CIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC33LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1377SEQ ID4RSCIDTIPKSECTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneN-acetylation at position 19LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1378SEQ ID5RSCIDTIPKSRCTAFECKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1379SEQ ID6RSCIDTIPKSRCTAFQCKKSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1380SEQ ID7RSCIDTIPKSRCTAFQCKHSMEYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1381SEQ ID8RSCIDTIPKSRCTAFQCKHSMKXYRLSFCRKTCGTC36LNoneNoneX = cyclohexylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1382SEQ ID9RSCIDTIPKSRCTAFQCKHSMAYRLSXCRKTCGTC35LNoneNoneX = cyclohexylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1383SEQ ID10RSCATIPKSRCTAAQCKHSMKYRLSFCRKRCGTC34LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1384SEQ ID11RSCIDSTIPKSRCTAAQKHSMKYRASFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1385SEQ ID12RSCADTIPKSRCTAAQCKHSMKYRASFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1386SEQ ID13SSCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1387SEQ ID14RSCIDTIPQSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1388SEQ ID15RSCIDTIPKSQCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1389SEQ ID16RSCIDTIPKSRCTAAQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1390SEQ ID17RSCIDTIPKSQCTAWQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1391SEQ ID18RSCIDTIPKSQCTAFQCAHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1392SEQ ID19RSCIDTIPKSQCTAFQCKHSXKYRLSFCRKTCGTC35LNoneNoneX = norleucine (nL)LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1393SEQ ID20RSCIDTIPKSRCTAFQCKHSMAYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1394SEQ ID21RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = norleucine (nL)LinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1395SEQ ID22RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = ornithineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1396SEQ ID23RSCIDTIPKSRCTAFQCKHSMXYRLSFCRKTCGTC35LNoneNoneX = homocitrullineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1397SEQ ID24RSCIDTIPKSRCTAFQCRHSMRYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1398SEQ ID25RSCIDTIPKSRCTAFQCKHSMKFRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1399SEQ ID26RSCIDTIPKSRCTAFQCKHSMKXRLSFCRKTCGTC35LNoneNoneX = nitrophenylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1400SEQ ID27RSCIDTIPKSRCTAFQCKHSMKXRLSFCRKTCGTC35LNoneNoneX = aminophenylalanineLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1401SEQ ID28RSCIDTIPKSRCTAFQCKHSMKYALSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1402SEQ ID29ASCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1403SEQ ID30RACIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1404SEQ ID31RSCADTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1405SEQ ID32RSCIATIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1406SEQ ID33RSCIDAIPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1407SEQ ID34RSCIDTAPKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1408SEQ ID35RSCIDTIAKSRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1409SEQ ID36RSCIDTIPASRCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1410SEQ ID37RSCIDTIPKARCTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1411SEQ ID38RSCIDTIPKSACTAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1412SEQ ID39RSCIDTIPKSRCAAFQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1413SEQ ID40RSCIDTIPKSRCTAAQCKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1414SEQ ID41RSCIDTIPKSRCTAFACKHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1415SEQ ID42RSCIDTIPKSRCTAFQCAHSMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000
1416SEQ ID43RSCIDTIPKSRCTAFQCKASMKYRLSFCRKTCGTC35LNoneNoneNoneLinearNaturalShk toxin of S.helianthusT Lymphocytes Kv1.3 channelsBy blocking the potassium channel, Kv1.3 of T lymphocytesBothPeripheral blood human lymhocytes1 nMCD18-nullPL/J miceEnzyme-linked immunosorbent assay (ELISA), HPLCNACharybdotoxin (ChTX)US 60776802000