A database of hormones and their receptors |
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HMRbase accession number | 10033 |
Swiss-prot Accession number | P51918 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Haplochromis burtoni (Burton's mouthbrooder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini;Astatotilapia. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Synthesized in preoptic neurons and is transported to the pituitary in the preoptic-hypophyseal axons |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins. May be responsible for the regulation of the hypothalamic-pituitary-gonadal axis |
Protein Length | 94 Amino acids |
Molecular weight | 10382 |
References | 1 PubMed abstract 7667296 2 PubMed abstract 9843638 3 PubMed abstract 7644702 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (23-32) |
Receptor | Q5UKX6 Detail in HMRbase Q90YM3 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 10038 |
Swiss-prot Accession number | P80677 (Sequence in FASTA format) |
Description | Gonadoliberin-1 (Gonadoliberin I) (Gonadotropin-releasing hormone I)(GnRH-I) (Luliberin I). |
Source organism | Chelyosoma productum |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Urochordata; Ascidiacea; Enterogona;Phlebobranchia; Corellidae; Chelyosoma. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | GNRH neurons lie within blood sinuses close to the gonoducts and gonads in both juveniles and adults, implying that the neuropeptide is released into the bloodstream |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 10 Amino acids |
Molecular weight | 1264 |
References | 1 PubMed abstract 8816823 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSDYFKPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10040 |
Swiss-prot Accession number | P81749 (Sequence in FASTA format) |
Description | Gonadoliberin-1 (Gonadoliberin I) (Gonadotropin-releasing hormone I)(GnRH-I) (LH-RH) (Luliberin I). |
Source organism | Clupea pallasii (Pacific herring) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Clupeomorpha; Clupeiformes;Clupeidae; Clupea. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 10 Amino acids |
Molecular weight | 1105 |
References | 1 PubMed abstract 10650929 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSHGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10069 |
Swiss-prot Accession number | Q8UW80 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) (Seabream-typegonadotropin-releasing hormone) (SbGnRH) [Contains: Gonadoliberin-1(Gonadoliberin I) (Luteinizing hormone-releasing hormone I) (LH-RH I)(Gonadotropin-releasing hormone I) (GnRH-I) (Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Verasper moseri (Barfin flounder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Pleuronectidae; Verasper. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Preoptic area of the brain |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 96 Amino acids |
Molecular weight | 10560 |
References | 1 PubMed abstract 12093120 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (27-36) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10078 |
Swiss-prot Accession number | Q95335 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Tupaia glis belangeri (Common tree shrew) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 92 Amino acids |
Molecular weight | 10197 |
References | 1 PubMed abstract 8921350 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10322 |
Swiss-prot Accession number | Q28588 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)](Fragment). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 61 Amino acids |
Molecular weight | 6828 |
References | 1 Rodriguez R.E., Wise M.E.; Submitted (OCT-1993) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 4550508 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | P32237
Detail in HMRbase |
Gene ID | N/A |
PDB ID | 1YY1 |
Drugpedia | wiki |
Comments |
HMRbase accession number | 10340 |
Swiss-prot Accession number | Q90Y63 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (LHRH I) (Luteinizing hormone-releasing hormone I) (Gonadotropin-releasing hormone I) (GnRH I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)(GAP1)]. |
Source organism | Rana catesbeiana (Bull frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
Subcellular location | Secreted protein |
Developmental Stage | Expressed at significantly higher levels during post-breeding. Not expressed in pituitary. |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Forebrain |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 90 Amino acids |
Molecular weight | 10291 |
References | 1 PubMed abstract 11170016 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (25-34) |
Receptor | Q9DE60 Detail in HMRbase Q9DE62 Detail in HMRbase Q9DE63 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 10409 |
Swiss-prot Accession number | P04378 (Sequence in FASTA format) |
Description | Gonadoliberin-1 (Gonadoliberin I) (Gonadotropin-releasing hormone I)(GnRH-I) (Luliberin I). |
Source organism | Petromyzon marinus (Sea lamprey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Hyperoartia;Petromyzontiformes; Petromyzontidae; Petromyzon. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 10 Amino acids |
Molecular weight | 1244 |
References | 1 PubMed abstract 3514603 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHYSLEWKPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10459 |
Swiss-prot Accession number | P37041 (Sequence in FASTA format) |
Description | Gonadoliberin-1 (Gonadoliberin I) (Gonadotropin-releasing hormone I)(GnRH-I) (LH-RH I) (Luliberin I). |
Source organism | Alligator mississippiensis (American alligator) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Crocodylidae; Alligatorinae; Alligator. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 10 Amino acids |
Molecular weight | 1172 |
References | 1 PubMed abstract 1882082 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLQPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10464 |
Swiss-prot Accession number | P51919 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Sparus aurata (Gilthead sea bream) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Sparidae; Sparus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 95 Amino acids |
Molecular weight | 10753 |
References | 1 PubMed abstract 7749463 2 PubMed abstract 7991588 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (26-35) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10505 |
Swiss-prot Accession number | P70074 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Pagrus major (Red sea bream) (Chrysophrys major) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Sparidae; Pagrus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 95 Amino acids |
Molecular weight | 10566 |
References | 1 Okuzawa K., Granneman J., Bogerd J., Goos H., Zohar Y., Kagawa H.; Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
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Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 11237 |
Swiss-prot Accession number | O54713 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 92 Amino acids |
Molecular weight | 10279 |
References | 1 PubMed abstract 9322920 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QYWSYGVRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | Q8CH60
Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11239 |
Swiss-prot Accession number | O73812 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Morone saxatilis (Striped bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Morone. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 95 Amino acids |
Molecular weight | 10411 |
References | 1 PubMed abstract 9845669 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-32) |
Receptor | Q9IA91
Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11243 |
Swiss-prot Accession number | P01148 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I) (Gonadorelin); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 92 Amino acids |
Molecular weight | 10380 |
References | 1 PubMed abstract 2671939 2 PubMed abstract 2867548 3 PubMed abstract 6090951 4 PubMed abstract 15489334 5 PubMed abstract 6760865 6 PubMed abstract 10391209 7 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | P30968
Detail in HMRbase |
Gene ID | 2796 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11385 |
Swiss-prot Accession number | P07490 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); Prolactin release-inhibiting factor 1 (Prolactinrelease-inhibiting factor I)]. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Central nervous system |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 92 Amino acids |
Molecular weight | 10500 |
References | 1 PubMed abstract 2867548 2 PubMed abstract 2476669 3 PubMed abstract 1468115 4 PubMed abstract 3547652 5 PubMed abstract 2867548 6 PubMed abstract 2476669 7 PubMed abstract 1468115 8 PubMed abstract 3547652 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | P30969
Detail in HMRbase |
Gene ID | 25194 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11408 |
Swiss-prot Accession number | P13562 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); Prolactin release-inhibiting factor 1 (Prolactinrelease-inhibiting factor I)]. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Secreted |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 90 Amino acids |
Molecular weight | 10337 |
References | 1 PubMed abstract 3024317 2 PubMed abstract 3024317 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-31) |
Receptor | Q01776
Detail in HMRbase |
Gene ID | 14714 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11439 |
Swiss-prot Accession number | P33439 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Clarias gariepinus (Sharptooth catfish) (African catfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;Clariidae; Clarias. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 80 Amino acids |
Molecular weight | 8893 |
References | 1 PubMed abstract 8020492 2 PubMed abstract 1520292 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSHGLNPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-31) |
Receptor | Q8JID0
Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11442 |
Swiss-prot Accession number | P37042 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 92 Amino acids |
Molecular weight | 10206 |
References | 1 PubMed abstract 7902095 2 PubMed abstract 7050119 3 King J.A., Millar R.P.; "Structure of avian hypothalamic gonadotrophin-releasing hormone."; S. Afr. J. Sci. 78:124-125(1982). 4 PubMed abstract 7050118 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLQPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | Q5EFE0 Detail in HMRbase Q9DDC9 Detail in HMRbase |
Gene ID | 770134 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11460 |
Swiss-prot Accession number | P45656 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); Gonadotropin-releasing hormone-associated peptide;GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 89 Amino acids |
Molecular weight | 10246 |
References | 1 PubMed abstract 8137750 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | Q9I8V4
Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11470 |
Swiss-prot Accession number | P49921 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 91 Amino acids |
Molecular weight | 10090 |
References | 1 Weesner G.D., Matteri R.L., Becker B.A.; Submitted (MAY-1994) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 4946067 3 PubMed abstract 4942726 4 PubMed abstract 4946275 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (24-33) |
Receptor | P49922
Detail in HMRbase |
Gene ID | 397516 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11481 |
Swiss-prot Accession number | P55247 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)](Fragment). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 67 Amino acids |
Molecular weight | 7573 |
References | 1 PubMed abstract 7545971 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (6-15) |
Receptor | Q8SPZ1
Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11509 |
Swiss-prot Accession number | Q9DGC8 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) (Medaka-typegonadotropin-releasing hormone) (mdGnRH) (mfGnRH) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | Expressed in the cell bodies of a cluster of neurons in the preoptic region |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 91 Amino acids |
Molecular weight | 10307 |
References | 1 PubMed abstract 11006121 2 PubMed abstract 12137956 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSFGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (22-31) |
Receptor | Q76KC7 Detail in HMRbase Q76L92 Detail in HMRbase Q76L93 Detail in HMRbase Q90VY1 Detail in HMRbase Q90W00 Detail in HMRbase |
Gene ID | 100049266 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11514 |
Swiss-prot Accession number | Q9IA10 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)]. |
Source organism | Dicentrarchus labrax (European sea bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Dicentrarchus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins |
Protein Length | 99 Amino acids |
Molecular weight | 10758 |
References | 1 PubMed abstract 11086295 |
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLSPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (27-36) |
Receptor | Q5TJK1 Detail in HMRbase Q8UUS1 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 11521 |
Swiss-prot Accession number | O09163 (Sequence in FASTA format) |
Description | Progonadoliberin-1 precursor (Progonadoliberin I) [Contains:Gonadoliberin-1 (Gonadoliberin I) (Luteinizing hormone-releasinghormone I) (LH-RH I) (Gonadotropin-releasing hormone I) (GnRH-I)(Luliberin I); GnRH-associated peptide 1 (GnRH-associated peptide I)](Fragment). |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the GnRH family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones |
Protein Length | 63 Amino acids |
Molecular weight | 7370 |
References | 1 Jansen H.T., Stevens P.J., Zeitler P., Lehman M.N.; Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
|
Domain Name | N/A |
Hormone Name | Gonadoliberin-1 |
Mature Hormone Sequence | QHWSYGLRPG |
Position of mature hormone in Pre-Hormone protein | 10 Residues from position (1-10) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |