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The total number entries retrieved from this search are 35
Please click on Biomarker_ID to view detailed information.
Note: Potential Biomarker with * indicates these signatures are candidate biomarkers extracted from experiments on mice, rat or cell lines and they are not validated on human patients'cohort.
Biomarker IDBiomarkerBiomoleculeSubjectRegulationBiomarker's typeExperimentLevel of significanceSourcePMID
2056Putrescine, spermidine, spermine, N-acetylspermine and N-acetylspermidineMetaboliteHumanUpregulated in the plasma of liver cancer patients than lung cancer patients DiagnosticHCC v/s Normal p < 0.05Urine and Plasma27517900
2057Spermine, followed by N-acetylspermidine, putrescine, cadaverine, spermidine, N-acetylspermine and N-acetylputrescineMetaboliteHumanUpregulated in the urine of liver cancer patients than lung cancer patients DiagnosticHCC v/s Normal p < 0.05Urine and Plasma27517900
2060UracilMetaboliteMiceDownregulated Potential Predictive *Cancer v/s Normal; Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2061cis-Aconitate acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2062D-4-PhosphopantothenateMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2063ProgesteroneMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
20645-Thymidylic acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
20652-Phospho-d-glyceric acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2066NiacinamideMetaboliteMiceUpregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2067CortisoneMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2068Imidazoleacetic acid ribotideMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
20693-Methyl-2-oxovaleric acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2070PseudoephedrineMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
20714-PhosphopantothenoylcysteineMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2072Pantetheine 4-phosphateMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2073Hippuric acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
20743-Hydroxyanthranilic acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2075GlycineMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2076CreatineMetaboliteMiceUpregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2077CortisolMetaboliteMiceUpregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2078Allantoic acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2079Pantothenic acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2080CreatinineMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2081UreaMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
20825-Hydroxyindoleacetic acidMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2083PhytosphingosineMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.05Urine and Plasma27077962
2084Imidazoleacetic acid ribosideMetaboliteMiceDownregulated Potential Predictive *Drug treated group v/s control group p < 0.01Urine and Plasma27077962
2113Alpha-ketoglutaricMetaboliteHumanThe concentrations of α-KG in diabetic II and liver cancer urine samples were significantly lower than those from healthy people. DiagnosticNormal vs cancer p < 0.05Urine25871588
2114pyruvic acidMetaboliteHumanThe concentrations of PA in diabetic II and liver cancer urine samples were significantly lower than those from healthy people. DiagnosticNormal vs cancer p < 0.05Urine25871588
2120D-glucurono-6,3-lactoneMetabolitesMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385
2121glycerol-3-phosphateMetaboliteMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385
2122pyruvic acidMetabolitesMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385
2123lithocholic acidMetabolitesMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385
21242-pyrocatechuic acidMetabolitesMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385
2125prostaglandin E1MetabolitesMiceUpregulated in AFLD Potential Predictive *Serum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled Serum24171385

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