CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2123
Detailed information
CancerLivER ID2123
Biomarkerlithocholic acid
Biomarker Name/Symbol (given in Publication)lithocholic acid
BiomoleculeMetabolites
SubjectMice
Degree of ValidityNon-invasive candidate biomarkers in the clinical application of AFLD for health management; but not validated in human patient cohorts
Experimental ConditionSerum biochemical analysis, antioxidant enzyme activity analysis, and histopathological evaluation revealed that GEO and citral exhibited hepatoprotective activity against AFLD. Metabolites in serum samples were profiled
Cancer typeAlcoholic fatty liver disease (AFLD)
RegulationUpregulated in AFLD
Level of significance
SourceSerum
PMID24171385
Type of BiomarkerPotential Predictive *
Pathwayarachidonic acid pathway, amino acid metabolism
CohortSix-week-old male C57BL/6 (B6) mice (BioLASCO Taiwan Co.) were maintained at the animal housing facility of the Institute of Food Science and Technology, National Taiwan University
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseMice, alcoholic fatty liver disease (AFLD)
Year of Publication2013
Clinical trialNO
Clinical trial (NCT Number)NA

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