CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2081
Detailed information
CancerLivER ID2081
BiomarkerUrea
Biomarker Name/Symbol (given in Publication)Urea
BiomoleculeMetabolite
SubjectMice
Degree of ValidityPotential predictive biomarkers in the drug hispidulin (5,7,4'-trihydroxy-6-methoxyflavone) groups; but not validated on human patient cohorts
Experimental ConditionDrug treated group v/s control group
Cancer typeHepatocellular carcinoma
RegulationDownregulated
Level of significance p < 0.05
SourceUrine and Plasma
PMID27077962
Type of BiomarkerPotential Predictive *
Pathwaypantothenate and CoA biosynthesis; glycine, serine and threonine metabolism; nicotinate and nicotinamide metabolism; steroid hormone biosynthesis; pyrimidine metabolism; and glyoxylate and dicarboxylate metabolism.
CohortAscitic hepatoma 22 (H22) cells of murine carcinoma were obtained from the Nanjing University of Chinese Medicine.
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
Diseasemice bearing neoplasm (H22) for hispidulin
Year of Publication2016
Clinical trialNO
Clinical trial (NCT Number)NA

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