CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2060
Detailed information
CancerLivER ID2060
BiomarkerUracil
Biomarker Name/Symbol (given in Publication)Uracil
BiomoleculeMetabolite
SubjectMice
Degree of ValidityPotential predictive biomarkers in the drug hispidulin (5,7,4'-trihydroxy-6-methoxyflavone) groups; but not validated on human patient cohorts
Experimental ConditionCancer v/s Normal; Drug treated group v/s control group
Cancer typeHepatocellular carcinoma
RegulationDownregulated
Level of significance p < 0.05
SourceUrine and Plasma
PMID27077962
Type of BiomarkerPotential Predictive *
Pathwaypantothenate and CoA biosynthesis metabolism, pyrimidine metabolism
CohortAscitic hepatoma 22 (H22) cells of murine carcinoma were obtained from the Nanjing University of Chinese Medicine.
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
Diseasemice bearing neoplasm (H22) for hispidulin
Year of Publication2016
Clinical trialYES
NCT No# (Clinical trial) NCT02447679,NCT01539018,NCT00464919,NCT00519688,NCT00384800

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