Detailed information |
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CancerLivER ID | 2078 |
Biomarker | Allantoic acid |
Biomarker Name/Symbol (given in Publication) | Allantoic acid |
Biomolecule | Metabolite |
Subject | Mice |
Degree of Validity | Potential predictive biomarkers in the drug hispidulin (5,7,4'-trihydroxy-6-methoxyflavone) groups; but not validated on human patient cohorts |
Experimental Condition | Drug treated group v/s control group |
Cancer type | Hepatocellular carcinoma |
Regulation | Downregulated |
Level of significance | p < 0.05 |
Source | Urine and Plasma |
PMID | 27077962 |
Type of Biomarker | Potential Predictive * |
Pathway | pantothenate and CoA biosynthesis; glycine, serine and threonine metabolism; nicotinate and nicotinamide metabolism; steroid hormone biosynthesis; pyrimidine metabolism; and glyoxylate and dicarboxylate metabolism. |
Cohort | Ascitic hepatoma 22 (H22) cells of murine carcinoma were obtained from the Nanjing University of Chinese Medicine. |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | mice bearing neoplasm (H22) for hispidulin |
Year of Publication | 2016 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |