Detailed information |
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CancerLivER ID | 2057 |
Biomarker | Spermine, followed by N-acetylspermidine, putrescine, cadaverine, spermidine, N-acetylspermine and N-acetylputrescine |
Biomarker Name/Symbol (given in Publication) | Spermine, followed by N-acetylspermidine, putrescine, cadaverine, spermidine, N-acetylspermine and N-acetylputrescine |
Biomolecule | Metabolite |
Subject | Human |
Degree of Validity | biomarkers for the characterization of lung and liver cancer; but not validated on independent dataset |
Experimental Condition | HCC v/s Normal |
Cancer type | Hepatocellular carcinoma |
Regulation | Upregulated in the urine of liver cancer patients than lung cancer patients |
Level of significance | p < 0.05 |
Source | Urine and Plasma |
PMID | 27517900 |
Type of Biomarker | Diagnostic |
Pathway | anabolic biosynthetic and catabolic pathways of polyamines |
Cohort | 50 healthy volunteers, 50 Liver cancer patients and 50 lung cancer patients. |
Sensitivity | NA |
Specificity | NA |
Accuracy | NA |
AUC | NA |
Disease | Human lung cancer, liver cancer |
Year of Publication | 2016 |
Clinical trial | NO |
Clinical trial (NCT Number) | NA |