CancerLivER: Biomarker Card

Biomarker Card: Comprehensive information about a biomarker


Biomarker ID 2057
Detailed information
CancerLivER ID2057
BiomarkerSpermine, followed by N-acetylspermidine, putrescine, cadaverine, spermidine, N-acetylspermine and N-acetylputrescine
Biomarker Name/Symbol (given in Publication)Spermine, followed by N-acetylspermidine, putrescine, cadaverine, spermidine, N-acetylspermine and N-acetylputrescine
BiomoleculeMetabolite
SubjectHuman
Degree of Validitybiomarkers for the characterization of lung and liver cancer; but not validated on independent dataset
Experimental ConditionHCC v/s Normal
Cancer typeHepatocellular carcinoma
RegulationUpregulated in the urine of liver cancer patients than lung cancer patients
Level of significance p < 0.05
SourceUrine and Plasma
PMID27517900
Type of BiomarkerDiagnostic
Pathwayanabolic biosynthetic and catabolic pathways of polyamines
Cohort50 healthy volunteers, 50 Liver cancer patients and 50 lung cancer patients.
SensitivityNA
SpecificityNA
AccuracyNA
AUCNA
DiseaseHuman lung cancer, liver cancer
Year of Publication2016
Clinical trialNO
Clinical trial (NCT Number)NA

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