Browse result page of AntiTbPdb
The total number entries retrieved from this search are 547
ID | Name | Sequence | N-Terminal Modification | C-Terminal Modification | Chemical Modification | Linear/Cyclic | Length | Chirality | Nature | Source | Origin | Species | Strain | Inhibition Concentration | In vitro/ In vivo | Cell Line | Intracellular Inhibition | Cytotoxicity | Animal Model | Effective Dose in model organism | Immune Responce | Mechanism of Action | Target | Combination Therapy | Other Activities | Year of Publication | Pubmed ID/ Patent No. |
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antitb_1001 | Polydim-I | AVAGEKLWLLPHLLKMLLTPTP | Free | Free | None | Linear | 22 | L | Amphipathic | Natural | Isolated from the venom of the Neotropical wasp Polybia dimorpha | Mycobacterium abscessus subsp. massiliense | Mycobacterium abscessus subsp. massiliense isolates GO 01, GO 06, GO 07, GO 08, GO 13, and GO 18, CRM0020 (Mycobacterium abscessus subsp. massiliense), and ATCC19977 (Mycobacterium abscessus subsp. abscessus) | MIC = 60.8 μg/mL | Both | Peritoneal macrophages, J774 macrophages cells, human red blood cells | Treatment of infected macrophages with 7.6 μg/mL of Polydim-I decreased approximately 50% of the bacterial load | Non-cytotoxic, 10% cytotoxicity on J774 cells at concentrations above 121.6 μg/mL (10%) and concentrations up to 121.6 μg/mL presented less than 2.5% of hemolytic activity | 6 to 8 weeks old BALB/c and IFN-γKO (Knockout) female mice | 2 mg/kg/mLW shows 90% reduction in bacterial load | NA | Cell wall disruption | Cell wall | None | NA | 2016 | 26930596 |
antitb_1025 | Seq1 | WKWLKKWIK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 1.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 24.3 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1026 | Seq1 | WKWLKKWIK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 1.9 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 24.3 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1027 | Seq2 | ILRWKWRWWRWRR | Free | Free | None | Linear | 13 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 2.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 25.2 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1028 | Seq2 | ILRWKWRWWRWRR | Free | Free | None | Linear | 13 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 2.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 50.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1029 | Seq 3 | ILPWKWRWWKWRR | Free | Free | None | Linear | 13 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 2.6 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 56.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1030 | Seq 3 | ILPWKWRWWKWRR | Free | Free | None | Linear | 13 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 2.2 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 56.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1031 | Seq 4 | RWRRKWWWW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 2.8 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 73.0 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1032 | Seq 4 | RWRRKWWWW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 5.7 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 =145.9 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1033 | Seq 5 | WRKFWKYLK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 3 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 47.3 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1034 | Seq 5 | WRKFWKYLK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 1.5 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 47.3 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1035 | Seq 6 | KRWWKWWRR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 3.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 79.2 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1036 | Seq 6 | KRWWKWWRR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 4.9 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 158.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1037 | Seq 7 | RRWWKWWWR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 3.6 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 152.6 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1038 | Seq 7 | RRWWKWWWR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 4.8 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 152.6 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1039 | Seq 8 | KIWWWWRKR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 4.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 173.9 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1040 | Seq 8 | KIWWWWRKR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 5.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 173.9 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1041 | Seq 9 | RLWWWWRRK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 4.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 87.0 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1042 | Seq 9 | RLWWWWRRK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 2.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 173.9 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1043 | Seq 10 | KWKWWWRKI | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 4.2 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 90.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1044 | Seq 10 | KWKWWWRKI | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 6.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 90.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1045 | Seq 11 | RIRRWKFRW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 4.3 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 182.5 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1046 | Seq 11 | RIRRWKFRW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 1.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 182.5 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1047 | Seq 12 | RLKRWWKFL | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 4.5 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 48.0 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1048 | Seq 12 | RLKRWWKFL | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 3 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 48.0 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1049 | Seq 13 | RWWRWRKWW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 4.6 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 =147.5 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1050 | Seq 13 | RWWRWRKWW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 4.6 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 =147.5 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1051 | Seq 14 | KRWWWWRFR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 5.2 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 83.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1052 | Seq 14 | KRWWWWRFR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 5.2 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 =166.7 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1053 | Seq 15 | KRWWRKWWR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 5.3 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 84.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1054 | Seq 15 | KRWWRKWWR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 5.3 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 84.4 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1055 | Seq 16 | RRWWRWVVW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 5.6 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 179.1 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1056 | Seq 16 | RRWWRWVVW | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 11.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 179.1 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1057 | Seq 17 | WFKMRWWGR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 5.9 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 =189.3 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1058 | Seq 17 | WFKMRWWGR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 2.2 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 =189.3 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1059 | Seq 18 | KFKWWRMLI | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 6.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 49.0 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1060 | Seq 18 | KFKWWRMLI | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 15.3 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 49.0 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1061 | Seq 19 | FIKWKFRWWKWRK | Free | Free | None | Linear | 13 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 7.4 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 14.8 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1062 | Seq 19 | FIKWKFRWWKWRK | Free | Free | None | Linear | 13 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 3.7 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 59.1 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1063 | Seq 20 | RIKRWWWWR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 7.8 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 167.2 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1064 | Seq 20 | RIKRWWWWR | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 4.6 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 167.2 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1065 | Seq 21 | RWRWWWRVY | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 8 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 171.5 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1066 | Seq 21 | RWRWWWRVY | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 6.7 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 171.5 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1067 | Seq 22 | HQFRFRFRVRRK | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 8.2 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 65.8 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1068 | Seq 22 | HQFRFRFRVRRK | Free | Free | None | Linear | 12 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 4.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 131.7 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1069 | Seq 23 | LKRRWKWWI | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 8.8 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 186.7 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1070 | Seq 23 | LKRRWKWWI | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 5.1 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 186.7 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1071 | Seq 24 | RRRIKIRWY | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 8.9 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 190.2 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1072 | Seq 24 | RRRIKIRWY | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium smegmatis | Mycobacterium smegmatis mc26 | MIC90 = 1.5 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC90 = 190.2 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |
antitb_1073 | Seq 25 | RLWWKIWLK | Free | Free | None | Linear | 9 | L | Cationic | Synthetic | NA | Mycobacterium tuberculosis | Mycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain | MIC90 = 9 μM | In vitro | THP-1 cells | NA | For THP-1 (infected wth M.tb) IC50 = 192.8 μM | None | NA | NA | NA | NA | None | Antibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis) | 2013 | 23478953 |