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KFKWWRMLI details
Primary information
ID antitb_1059,
Name23478953
N-Terminal modificationSeq 18
C-Terminal ModificationKFKWWRMLI
Chemical ModificationFree
Linear/CyclicFree
LengthNone
ChiralityLinear
Nature9
SourceL
OriginCationic
SpeciesSynthetic
Inhibition ConcentrationMycobacterium tuberculosis
In Vitro/ In vivoMycobacterium tuberculosis H37Rv, and the Mycobacterium tuberculosis lux strain
Cell LineMIC90 = 6.1 μM
Inhibition ConcentrationIn vitro
Sequence2013
CytotoxicityTHP-1 cells
In vivo ModelNA
Lethal DoseFor THP-1 (infected wth M.tb) IC50 = 49.0 μM
Immune ResponceNone
Mechanism of ActionNA
TargetNA
Combination TherapyNA
Other activitiesNA
PMIDNone
Year of PublicationAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)
Tertiary Structure
(Technique)
Not Predicted),
Primary information
ID antitb_1060,
Name23478953
N-Terminal modificationSeq 18
C-Terminal ModificationKFKWWRMLI
Chemical ModificationFree
Linear/CyclicFree
LengthNone
ChiralityLinear
Nature9
SourceL
OriginCationic
SpeciesSynthetic
Inhibition ConcentrationMycobacterium smegmatis
In Vitro/ In vivoMycobacterium smegmatis mc26
Cell LineMIC90 = 15.3 μM
Inhibition ConcentrationIn vitro
Sequence2013
CytotoxicityTHP-1 cells
In vivo ModelNA
Lethal DoseFor THP-1 (infected wth M.tb) IC90 = 49.0 μM
Immune ResponceNone
Mechanism of ActionNA
TargetNA
Combination TherapyNA
Other activitiesNA
PMIDNone
Year of PublicationAntibacterial and Antifungal (P. aeruginosa, Escherichia coli, Salmonella enterica serovar Typhimurium, Candida albicans, Streptococcus epidermidis, Staphylococcus aureus, and Enterococcus faecalis)
Tertiary Structure
(Technique)
Not Predicted),