Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_1765Lipopolysaccharide (LPS)

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Gram negative bacteria, Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantDjCTLC type Lectin (CTL/CLR)Dugesia japonicapharyngeal and epidermisdomain of CLECTA0A1L2DBR5.fastaA0A1L2DBR5107foreign invaders and phagocytize or encapsulate the aggregates of killed bacteria which have been digested in intestinal cavity.Microbial binding assay275654082016Pubchem_assay
PRRID_1765Lipopolysaccharide (LPS)

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Gram negative bacteria, Gram-positive bacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalImmunostimulantDjCTLC type Lectin (CTL/CLR)Dugesia japonicapharyngeal and epidermisdomain of CLECTA0A1L2DBR5.fastaA0A1L2DBR5107foreign invaders and phagocytize or encapsulate the aggregates of killed bacteria which have been digested in intestinal cavity.Microbial binding assay275654082016Pubchem_assay
PRRID_1789Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1789Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1790Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1790Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1791 b-1, 3-glucans

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAProteinNaturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1791 b-1, 3-glucans

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAProteinNaturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1792Lipoteichoic Acid (LTA)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAAmphiphileNaturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1792Lipoteichoic Acid (LTA)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAAmphiphileNaturalelicit innate immune responseMnCTLDcp2C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1793Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responseMnCTLDcp3C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1793Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responseMnCTLDcp3C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1796b-1, 3-glucans

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAProteinNaturalelicit innate immune responseMnCTLDcp3C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1796b-1, 3-glucans

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAProteinNaturalelicit innate immune responseMnCTLDcp3C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1797Lipoteichoic Acid (LTA)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAAmphiphileNaturalelicit innate immune responseMnCTLDcp3C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1797Lipoteichoic Acid (LTA)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAAmphiphileNaturalelicit innate immune responseMnCTLDcp3C type Lectin (CTL/CLR)NANANANANANANANA262087552016NA
PRRID_1802mannitol-linked glycerogly- colipid

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp. (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1802mannitol-linked glycerogly- colipid

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp. (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1803Mannose

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HIV-1 (virus)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1803Mannose

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HIV-1 (virus)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDCIRC type Lectin (CTL/CLR)HumanNANANANANAInhibition of APC functions such as cytokine productionNA279999922016NA
PRRID_1804Mannose

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusC(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1804Mannose

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusC(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1805mannosyl fatty acids

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1805mannosyl fatty acids

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1812NA

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Vibrio harveyi (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantPmCLecC type Lectin (CTL/CLR)Penaeus monodonlymphoid organ.carbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay278766222016NA
PRRID_1812NA

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Vibrio harveyi (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantPmCLecC type Lectin (CTL/CLR)Penaeus monodonlymphoid organ.carbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay278766222016NA
PRRID_1823NA

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Vibrio vulnificus (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliikidney, liver, spleen and macrophagescarbohydrate-recognition domain (CRD),NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1823NA

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Vibrio vulnificus (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliikidney, liver, spleen and macrophagescarbohydrate-recognition domain (CRD),NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1824NA

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Vibrio ichthyoenteri (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliiKidney, liver, spleen and macrophagesCarbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1824NA

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Vibrio ichthyoenteri (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantrSsLec1C type Lectin (CTL/CLR)Sebastes schlegeliiKidney, liver, spleen and macrophagesCarbohydrate recognition domain (CRD)NANANAActivate NF-KBMicrobial binding assay275699822016NA
PRRID_1836O-linked mannobiose-rich glycoprotein

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1836O-linked mannobiose-rich glycoprotein

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1840Peptidoglycan (PGN)

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Gram negative bacteria, Gram-positive bacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalImmunostimulantDjCTLC type Lectin (CTL/CLR)Dugesia japonicaPharyngeal and epidermisDoamin of CLECTA0A1L2DBR5.fastaA0A1L2DBR5107foreign invaders and phagocytize or encapsulate the aggregates of killed bacteria which have been digested in intestinal cavity.Microbial binding assay275654082016Pubchem_assay
PRRID_1840Peptidoglycan (PGN)

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Gram negative bacteria, Gram-positive bacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalImmunostimulantDjCTLC type Lectin (CTL/CLR)Dugesia japonicaPharyngeal and epidermisDoamin of CLECTA0A1L2DBR5.fastaA0A1L2DBR5107foreign invaders and phagocytize or encapsulate the aggregates of killed bacteria which have been digested in intestinal cavity.Microbial binding assay275654082016Pubchem_assay
PRRID_1852polyinosinic-polycytidylic acid [poly(I:C)]

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NAC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)ONANucleic AcidSyntheticImmunostimulantLcNTCC type Lectin (CTL/CLR)Larimichthys crocealiver, spleen and head-kidneyCRD with four conserved disulfide-bonded cysteine residues (Cys -Cys , Cys -Cys ) and EPN/AND motifs NANANAServe as a PRR involved in fish defense against virus, bacteria and parasites infection through recognizing carbohydrates on the surface of pathogens.Bacterial agglutination assay268282632016NA
PRRID_1852polyinosinic-polycytidylic acid [poly(I:C)]

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NAC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)ONANucleic AcidSyntheticImmunostimulantLcNTCC type Lectin (CTL/CLR)Larimichthys crocealiver, spleen and head-kidneyCRD with four conserved disulfide-bonded cysteine residues (Cys -Cys , Cys -Cys ) and EPN/AND motifs NANANAServe as a PRR involved in fish defense against virus, bacteria and parasites infection through recognizing carbohydrates on the surface of pathogens.Bacterial agglutination assay268282632016NA
PRRID_1868sialyl-Lex

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1868sialyl-Lex

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S. pneumoniae, K. pneumoniae, C. albicans, P.carinii, HIV-1, Dengue virusNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMMRC type Lectin (CTL/CLR)HumanNANANANANAPathogen recognition; Antigen uptake; Cell adhesion; PhagocytosisNA279999922016NA
PRRID_1875TDM

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1875TDM

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1884α-Mannose

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1884α-Mannose

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M. tuberculosis, S. enterica, S. mansoni, C. albicans, A. fumigatus, Malassezia spp.(Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-2C type Lectin (CTL/CLR)HumanNANAQ6EIG7.fastaQ6EIG7209Pathogen recognition; antigen uptakeNA279999922016Pubchem_assay
PRRID_1885α-Mannose

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1885α-Mannose

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M. tuberculosis, S. pneumoniae, K. pneumo- niae, H. pylori, C. albicans, Malassezia spp.(Bacteria)C(C1C(C(C(C(O1)O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantMincleC type Lectin (CTL/CLR)HumanNANANANANARecognition of pathogens and necrotic cells; Induction of cytokine productionNA279999922016NA
PRRID_1886β -1,3-glucan

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Mycobacterium spp., L. infantum, C. albicans P. carinii, A. fumigatus, C. neoformansC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-1C type Lectin (CTL/CLR)HumanNANAQ9BXN2.fastaQ9BXN2247Pathogen recognition; T cell differentiationNA279999922016Pubchem_assay
PRRID_1886β -1,3-glucan

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Mycobacterium spp., L. infantum, C. albicans P. carinii, A. fumigatus, C. neoformansC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-1C type Lectin (CTL/CLR)HumanNANAQ9BXN2.fastaQ9BXN2247Pathogen recognition; T cell differentiationNA279999922016Pubchem_assay
PRRID_1888β­glucan

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pathogenic fungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAGlycoproteinNaturalFungal infectionDectin-1C type Lectin (CTL/CLR)NAmacrophages, den- dritic cells, neutrophils, and a subset of T and B cellscarbohydrate domainNANANAphagocytosis of fungiNA272884072016NA
PRRID_1888β­glucan

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pathogenic fungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAGlycoproteinNaturalFungal infectionDectin-1C type Lectin (CTL/CLR)NAmacrophages, den- dritic cells, neutrophils, and a subset of T and B cellscarbohydrate domainNANANAphagocytosis of fungiNA272884072016NA
PRRID_18921,3 beta glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA272884072017NA
PRRID_18921,3 beta glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA272884072017NA
PRRID_1910alpha-mannans

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Candida albicans(fungi)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNANANaturalNACLEC6A (Dectin-2)C type Lectin (CTL/CLR)HumanNAC-Type Lectin Domain Family 4, Member MQ6EIG7.fastaQ6EIG7209NANA290662552017Pubchem_assay
PRRID_1910alpha-mannans

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Candida albicans(fungi)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNANANaturalNACLEC6A (Dectin-2)C type Lectin (CTL/CLR)HumanNAC-Type Lectin Domain Family 4, Member MQ6EIG7.fastaQ6EIG7209NANA290662552017Pubchem_assay
PRRID_1946b-1,3-glucans.

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Candida glabrata(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalBinding and activation of Dectin -1Dectin-1C type Lectin (CTL/CLR)MiceMacrophagesNAQ9BXN2.fastaQ9BXN2247activation of the NF-κB and MAPK pathwaysBinding assay286585922017Pubchem_assay
PRRID_1946b-1,3-glucans.

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Candida glabrata(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalBinding and activation of Dectin -1Dectin-1C type Lectin (CTL/CLR)MiceMacrophagesNAQ9BXN2.fastaQ9BXN2247activation of the NF-κB and MAPK pathwaysBinding assay286585922017Pubchem_assay
PRRID_1954Beta glucans

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Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAGlucanNaturalActivation of CLEC7ACLEC7AC type Lectin (CTL/CLR)HumanNANAQ9BXN2.fastaQ9BXN2247critical functions in host defense against Candida albicans invasionNA288241662017Pubchem_assay
PRRID_1954Beta glucans

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Candida albicans(fungi)C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAGlucanNaturalActivation of CLEC7ACLEC7AC type Lectin (CTL/CLR)HumanNANAQ9BXN2.fastaQ9BXN2247critical functions in host defense against Candida albicans invasionNA288241662017Pubchem_assay
PRRID_1955beta-1,3-linked

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FungiNANANANaturalNACLEC7AC type Lectin (CTL/CLR)HumanNAC-Type Lectin Domain Family 7, Member A,Q9BXN2.fastaQ9BXN2247NANA290662552017Pubchem_assay
PRRID_1955beta-1,3-linked

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FungiNANANANaturalNACLEC7AC type Lectin (CTL/CLR)HumanNAC-Type Lectin Domain Family 7, Member A,Q9BXN2.fastaQ9BXN2247NANA290662552017Pubchem_assay
PRRID_1956beta-1,6-linked glucans

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONANANaturalNACLEC7AC type Lectin (CTL/CLR)HumanNANAQ9BXN2.fastaQ9BXN2247NANA290662552017Pubchem_assay
PRRID_1956beta-1,6-linked glucans

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONANANaturalNACLEC7AC type Lectin (CTL/CLR)HumanNANAQ9BXN2.fastaQ9BXN2247NANA290662552017Pubchem_assay
PRRID_1976Chitin

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protozoa, fungi, arthropods, and nematodes (others)NANAPattern-associated molecular patterns (PAMPs)NaturalChitin induces cy- tokine production, leukocyte recruitment, and alternative mac- rophage activationDectin-1C type Lectin (CTL/CLR) HumanLungs and gutNANANANAActivate immune cells to induce cytokine productionNA282515812017NA
PRRID_1976Chitin

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protozoa, fungi, arthropods, and nematodes (others)NANAPattern-associated molecular patterns (PAMPs)NaturalChitin induces cy- tokine production, leukocyte recruitment, and alternative mac- rophage activationDectin-1C type Lectin (CTL/CLR) HumanLungs and gutNANANANAActivate immune cells to induce cytokine productionNA282515812017NA
PRRID_2017endogenous glycoproteins

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NANANADamage-associated molecular patterns (DAMPs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2017endogenous glycoproteins

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NANANADamage-associated molecular patterns (DAMPs)Naturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2064galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFmLC3C type Lectin (CTL/CLR)Fenneropenaeus merguiensishepatopancreascarbohydrate recognition domain with an EPN motif and one Ca2+ binding site-2, including a double- loop region assisted by two conserved disulfide linkages.NANANANAwestern blotting290551892017NA
PRRID_2064galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFmLC3C type Lectin (CTL/CLR)Fenneropenaeus merguiensishepatopancreascarbohydrate recognition domain with an EPN motif and one Ca2+ binding site-2, including a double- loop region assisted by two conserved disulfide linkages.NANANANAwestern blotting290551892017NA
PRRID_2065galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFmLC2C type Lectin (CTL/CLR)Fenneropenaeus merguiensisNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2065galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFmLC2C type Lectin (CTL/CLR)Fenneropenaeus merguiensisNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2066galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFmLC4C type Lectin (CTL/CLR)Fenneropenaeus merguiensisNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2066galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFmLC4C type Lectin (CTL/CLR)Fenneropenaeus merguiensisNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2067galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responsePmLecC type Lectin (CTL/CLR)Penaeus monodonNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2067galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responsePmLecC type Lectin (CTL/CLR)Penaeus monodonNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2068galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFcLec4C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreas, gills and stomachCRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2068galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFcLec4C type Lectin (CTL/CLR)Fenneropenaeus chinensishepatopancreas, gills and stomachCRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2069galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFcLec6C type Lectin (CTL/CLR)Fenneropenaeus chinensisNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2069galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseFcLec6C type Lectin (CTL/CLR)Fenneropenaeus chinensisNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2070galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseLvLectin-2C type Lectin (CTL/CLR)Litopenaeus vannameiNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2070galactose

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BacteriaC(C(C(C(C(C=O)O)O)O)O)ONANANaturalelicit innate immune responseLvLectin-2C type Lectin (CTL/CLR)Litopenaeus vannameiNACRD with a QPD (Gln-Pro-Asp) motifNANANANANA290551892017NA
PRRID_2073Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseAmphiCTL1C type Lectin (CTL/CLR)B. belcheriNANANANANANANA290551892017NA
PRRID_2073Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseAmphiCTL1C type Lectin (CTL/CLR)B. belcheriNANANANANANANA290551892017NA
PRRID_2074Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorrPtCTL-2C type Lectin (CTL/CLR)Portunus trituberculatusNACarbohydrate recognition DomainNANANArecognize nonself invaders and also work as an opsonin to eliminate invadersPAMPs binding assay289163582017NA
PRRID_2074Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalinnate immunity elicitorrPtCTL-2C type Lectin (CTL/CLR)Portunus trituberculatusNACarbohydrate recognition DomainNANANArecognize nonself invaders and also work as an opsonin to eliminate invadersPAMPs binding assay289163582017NA
PRRID_2077Glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2077Glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responseDectin-1C type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2081Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2081Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2082Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2082Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2083Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2083Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA289163582017NA
PRRID_2084Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA282889102017NA
PRRID_2084Glucan

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BacteriaC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONACarbohydrateNaturalelicit innate immune responserPtCTL-2C type Lectin (CTL/CLR)NANANANANANANANA282889102017NA
PRRID_2085Glycans

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Bacteria(Gram negative, Gram positive)NANAPattern-associated molecular patterns (PAMPs)Naturalinnate immunity elicitorMjCC-CLC type Lectin (CTL/CLR)kuruma shrimp (Marsupenaeus japonicus)intestineC-type carbohydrate recogni- tion domainNANANACTL acti- vates the JAK/STAT signaling pathway and regulates AMP expression.Recombinanat Protein Binding Assay289310612017NA
PRRID_2085Glycans

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Bacteria(Gram negative, Gram positive)NANAPattern-associated molecular patterns (PAMPs)Naturalinnate immunity elicitorMjCC-CLC type Lectin (CTL/CLR)kuruma shrimp (Marsupenaeus japonicus)intestineC-type carbohydrate recogni- tion domainNANANACTL acti- vates the JAK/STAT signaling pathway and regulates AMP expression.Recombinanat Protein Binding Assay289310612017NA
PRRID_2086Glycans

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BacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantHaCTL3C type Lectin (CTL/CLR)Helicoverpa armigeraHemocytesNANANANAHaCTL3 enhances hemocytic encapsulation and melanizationqRT-PCR285720002017NA
PRRID_2086Glycans

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BacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantHaCTL3C type Lectin (CTL/CLR)Helicoverpa armigeraHemocytesNANANANAHaCTL3 enhances hemocytic encapsulation and melanizationqRT-PCR285720002017NA
PRRID_2089Glycolipids

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BacteriaNANAPattern-associated molecular patterns (PAMPs)Naturalelicit innate immune responseMincleC type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2089Glycolipids

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BacteriaNANAPattern-associated molecular patterns (PAMPs)Naturalelicit innate immune responseMincleC type Lectin (CTL/CLR)NANANANANANANANA288015212017NA
PRRID_2090glycomimetic

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NANANAAgonistSyntheticActivation of CLRs.DC-SIGNC type Lectin (CTL/CLR)HumanPlasma membranecarbohydrate recognition domain (CRD)NANANAinhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways.Flow cytometry287764162017NA
PRRID_2090glycomimetic

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NANANAAgonistSyntheticActivation of CLRs.DC-SIGNC type Lectin (CTL/CLR)HumanPlasma membranecarbohydrate recognition domain (CRD)NANANAinhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways.Flow cytometry287764162017NA