Browse result page of PRRDB 2.0

PRRID	Name of Ligand	Source of ligand	Sequence of Ligand	Length of Ligand	Type of Ligand	Occurence	Role of Ligand	Name of Receptor	Type of Reeptor	Source of the Receptor	Localization	Domain	Sequence of Receptor	Swiss prot ID	Length of receptor	Function of Receptor	Assay used	PMID	Year of publication	Pubchem assay
PRRID_1894	5‚-dsRNA Click for more detail	EBOV, MV, SeV, NDV, RSV, flu virus, hantavirus,VSV, RV, HCV, JEV, adenovirus, vaccinia virus, HSV,L.	NA	NA	Nucleic Acid	Natural	K63-polyubiquitination/ polyubiquitin chain binding mediated receptor tetramerization	RIG-1	Rig-like receptor (RLR)	Human	Cytoplasm, all mammalian cell types	NA	O95786.fasta	O95786	925	MAVS-TRAF3-TBK1/ IKKe-IRF3. MAVS-FADD/ TRAF6-IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1894	5‚-dsRNA Click for more detail	EBOV, MV, SeV, NDV, RSV, flu virus, hantavirus,VSV, RV, HCV, JEV, adenovirus, vaccinia virus, HSV,L.	NA	NA	Nucleic Acid	Natural	K63-polyubiquitination/ polyubiquitin chain binding mediated receptor tetramerization	RIG-1	Rig-like receptor (RLR)	Human	Cytoplasm, all mammalian cell types	NA	O95786.fasta	O95786	925	MAVS-TRAF3-TBK1/ IKKe-IRF3. MAVS-FADD/ TRAF6-IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1895	6-O-stearoyl-MDP (L18- MDP) Click for more detail	NA	CCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C	NA	Peptide	Synthetic	Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-Œ∫B-mediated expression of inflammatory cytokines	Nod-like receptor C2 (NLRC2)	NOD-like receptor (NLR)	Human	Intracellular	C-terminal leucine-rich regions and NOD domains	NA	NA	NA	triggering production of Œ≤-defensins via an NF-Œ∫B signaling pathway	NA	28776416	2017	NA
PRRID_1895	6-O-stearoyl-MDP (L18- MDP) Click for more detail	NA	CCCCCCCCCCCCCCCCCC(=O)NCCCCC(C(=O)O)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C	NA	Peptide	Synthetic	Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-Œ∫B-mediated expression of inflammatory cytokines	Nod-like receptor C2 (NLRC2)	NOD-like receptor (NLR)	Human	Intracellular	C-terminal leucine-rich regions and NOD domains	NA	NA	NA	triggering production of Œ≤-defensins via an NF-Œ∫B signaling pathway	NA	28776416	2017	NA
PRRID_1896	9-O-acetylated 2‚Äì6-linked sialic acid derivatives Click for more detail	NA	NA	NA	NA	Natural	NA	FCN1	Pattern recognition receptor (PRR)	Human	NA	Ficolin (Collagen/Fibrinogen Domain Containing) 1	O00602.fasta	O00602	326	NA	NA	29066255	2017	Pubchem_assay
PRRID_1896	9-O-acetylated 2‚Äì6-linked sialic acid derivatives Click for more detail	NA	NA	NA	NA	Natural	NA	FCN1	Pattern recognition receptor (PRR)	Human	NA	Ficolin (Collagen/Fibrinogen Domain Containing) 1	O00602.fasta	O00602	326	NA	NA	29066255	2017	Pubchem_assay
PRRID_1899	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	NA	NA	Q96P20.fasta	Q96P20	1036	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1899	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	NA	NA	Q96P20.fasta	Q96P20	1036	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1900	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Human	NA	NA	Q9C000.fasta	Q9C000	1473	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1900	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Human	NA	NA	Q9C000.fasta	Q9C000	1473	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1901	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	cluster of differentiation 36 (CD36)	Pattern recognition receptor (PRR)	Human	NA	NA	P16671.fasta	P16671	472	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1901	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	cluster of differentiation 36 (CD36)	Pattern recognition receptor (PRR)	Human	NA	NA	P16671.fasta	P16671	472	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1902	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	cluster of differentiation 14 (CD14)	Pattern recognition receptor (PRR)	Human	NA	NA	P08571.fasta	P08571	375	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1902	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	cluster of differentiation 14 (CD14)	Pattern recognition receptor (PRR)	Human	NA	NA	P08571.fasta	P08571	375	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1903	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1903	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1904	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	RAGE	Receptor for advanced glycation endproducts (RAGE)	Human	NA	NA	Q15109.fasta	Q15109	404	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1904	Ab Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	Cellular injury and necrosis	RAGE	Receptor for advanced glycation endproducts (RAGE)	Human	NA	NA	Q15109.fasta	Q15109	404	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1907	Ag85 complex Click for more detail	Mycobacteria (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	causes tuberculosis-like systemic infection in sh and in other ectotherms	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	THP‚Äê1 macrophages	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	THP‚Äê1 cell culture ,FACS LSR II BD ow cytom- eter ,ELISA	29183333	2017	Pubchem_assay
PRRID_1907	Ag85 complex Click for more detail	Mycobacteria (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	causes tuberculosis-like systemic infection in sh and in other ectotherms	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	THP‚Äê1 macrophages	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	THP‚Äê1 cell culture ,FACS LSR II BD ow cytom- eter ,ELISA	29183333	2017	Pubchem_assay
PRRID_1908	Ag85 complex Click for more detail	Mycobacteria (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	causes tuberculosis-like systemic infection in sh and in other ectotherms	CR3	Complement Receptor	Human	THP‚Äê1 macrophages	NA	NA	NA	NA	NA	THP‚Äê1 cell culture ,FACS LSR II BD ow cytom- eter ,ELISA	29183333	2017	NA
PRRID_1908	Ag85 complex Click for more detail	Mycobacteria (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	causes tuberculosis-like systemic infection in sh and in other ectotherms	CR3	Complement Receptor	Human	THP‚Äê1 macrophages	NA	NA	NA	NA	NA	THP‚Äê1 cell culture ,FACS LSR II BD ow cytom- eter ,ELISA	29183333	2017	NA
PRRID_1910	alpha-mannans Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	NA	Natural	NA	CLEC6A (Dectin-2)	C type Lectin (CTL/CLR)	Human	NA	C-Type Lectin Domain Family 4, Member M	Q6EIG7.fasta	Q6EIG7	209	NA	NA	29066255	2017	Pubchem_assay
PRRID_1910	alpha-mannans Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	NA	Natural	NA	CLEC6A (Dectin-2)	C type Lectin (CTL/CLR)	Human	NA	C-Type Lectin Domain Family 4, Member M	Q6EIG7.fasta	Q6EIG7	209	NA	NA	29066255	2017	Pubchem_assay
PRRID_1913	Amyloid-Œ≤ fibrils Click for more detail	NA	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Damage-associated molecular patterns (DAMPs)	Natural	Immunostimulant	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Brain	NA	Q96P20.fasta	Q96P20	1036	protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits	NA	28801521	2017	Pubchem_assay
PRRID_1913	Amyloid-Œ≤ fibrils Click for more detail	NA	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Damage-associated molecular patterns (DAMPs)	Natural	Immunostimulant	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Brain	NA	Q96P20.fasta	Q96P20	1036	protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits	NA	28801521	2017	Pubchem_assay
PRRID_1916	analog poly I:C Click for more detail	MCMV, HSV-1, EMCV, WNV,and enteroviruses (virus)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Synthetic	dsRNA induced dimerization	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Endosomes. Innate immune cells except neutrophils and pDCs	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	TRIF-TRAF3-TBK1/ IKKe-IRF3. TRIF-TRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1916	analog poly I:C Click for more detail	MCMV, HSV-1, EMCV, WNV,and enteroviruses (virus)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Synthetic	dsRNA induced dimerization	Toll-like receptor 3 (TLR3)	Toll-like receptor (TLR)	Human	Endosomes. Innate immune cells except neutrophils and pDCs	Leucine-rich Repeat (LRR) Domain	O15455.fasta	O15455	904	TRIF-TRAF3-TBK1/ IKKe-IRF3. TRIF-TRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1918	Anthrax lethal toxin Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Human	hippocampus (neurons)	NA	Q9C000.fasta	Q9C000	1473	protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment	NA	28801521	2017	Pubchem_assay
PRRID_1918	Anthrax lethal toxin Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Human	hippocampus (neurons)	NA	Q9C000.fasta	Q9C000	1473	protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairment	NA	28801521	2017	Pubchem_assay
PRRID_1921	Anthrax lethal toxin Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Human	Brain	NA	Q9C000.fasta	Q9C000	1473	protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits	NA	28801521	2017	Pubchem_assay
PRRID_1921	Anthrax lethal toxin Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor protein 1 (NLRP1)	NOD-like receptor (NLR)	Human	Brain	NA	Q9C000.fasta	Q9C000	1473	protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits	NA	28801521	2017	Pubchem_assay
PRRID_1924	ATI-2341 Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	innate immunity elicitor	FPR2(Formyl peptide Receptor2)	Pattern recognition receptor (PRR)	Human	Neutrophils	Seven alpha helical transmembrane domains	P25090.fasta	P25090	351	tissue homeostasis, host defence reactivity and regulation of immune reactions and inflammation,	Neutrophil NADPH oxidase assay	28881079	2017	Pubchem_assay
PRRID_1924	ATI-2341 Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	innate immunity elicitor	FPR2(Formyl peptide Receptor2)	Pattern recognition receptor (PRR)	Human	Neutrophils	Seven alpha helical transmembrane domains	P25090.fasta	P25090	351	tissue homeostasis, host defence reactivity and regulation of immune reactions and inflammation,	Neutrophil NADPH oxidase assay	28881079	2017	Pubchem_assay
PRRID_1928	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Brain	NA	Q96P20.fasta	Q96P20	1036	protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits	NA	28801521	2017	Pubchem_assay
PRRID_1928	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Brain	NA	Q96P20.fasta	Q96P20	1036	protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficits	NA	28801521	2017	Pubchem_assay
PRRID_1931	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Activate human dendritic cells	P2X7R	NOD-like receptor (NLR)	Human	Dendritic cells	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1931	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Activate human dendritic cells	P2X7R	NOD-like receptor (NLR)	Human	Dendritic cells	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1932	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Activate human dendritic cells	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Dendritic cells	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1932	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Activate human dendritic cells	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Dendritic cells	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1933	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ and IL-18 by human monocytes	P2X7R	NOD-like receptor (NLR)	Human	Monocyte	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1933	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ and IL-18 by human monocytes	P2X7R	NOD-like receptor (NLR)	Human	Monocyte	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1934	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ and IL-18 by human monocytes	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Monocyte	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1934	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ and IL-18 by human monocytes	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Monocyte	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1935	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ by murine and human neutrophils	P2X7R	NOD-like receptor (NLR)	Human	Neutrophils	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1935	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ by murine and human neutrophils	P2X7R	NOD-like receptor (NLR)	Human	Neutrophils	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1936	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ by murine and human neutrophils	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Neutrophils	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1936	ATP Click for more detail	NA	C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O	NA	Damage-associated molecular patterns (DAMPs)	Natural	Induce the secretion of IL-1Œ≤ by murine and human neutrophils	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	Neutrophils	NA	Q96P20.fasta	Q96P20	1036	NA	NA	28961019	2017	Pubchem_assay
PRRID_1948	b-Gentiobiosyl diaglycerides Click for more detail	Mtb H37Ra (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1948	b-Gentiobiosyl diaglycerides Click for more detail	Mtb H37Ra (Bacteria)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1949	Bacterial flagella Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Fatty acid	Natural	NA	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	cell surface	Leucine-rich Repeat (LRR) Domain	O60602.fasta	O60602	858	NA	NA	29263932	2017	Pubchem_assay
PRRID_1949	Bacterial flagella Click for more detail	Bacteria	MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR	495	Fatty acid	Natural	NA	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	cell surface	Leucine-rich Repeat (LRR) Domain	O60602.fasta	O60602	858	NA	NA	29263932	2017	Pubchem_assay
PRRID_1950	Bacterial lipoprotein Click for more detail	Bacteria	NA	NA	NA	Natural	Enhance antigen uptake and simultaneously increases cytokine production ,IL-ÔôÄ production, DC maturation, cell activation, induce NFŒ∫B activation	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	NA	29028369	2017	Pubchem_assay
PRRID_1950	Bacterial lipoprotein Click for more detail	Bacteria	NA	NA	NA	Natural	Enhance antigen uptake and simultaneously increases cytokine production ,IL-ÔôÄ production, DC maturation, cell activation, induce NFŒ∫B activation	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O60603.fasta	O60603	784	NA	NA	29028369	2017	Pubchem_assay
PRRID_1952	Bacterial MDP Click for more detail	RSV, IAV, and HCMV (virus)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Likely tetramerization into washer- locker structure	Nucleotide Binding Oligomerization Domain Containing 2 (Nod2)	NOD-like receptor (NLR)	Human	Cytoplasm. Macrophages, monocytes, Paneth cells, DCs	NA	Q9HC29.fasta	Q9HC29	1040	RIP2-IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1952	Bacterial MDP Click for more detail	RSV, IAV, and HCMV (virus)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Likely tetramerization into washer- locker structure	Nucleotide Binding Oligomerization Domain Containing 2 (Nod2)	NOD-like receptor (NLR)	Human	Cytoplasm. Macrophages, monocytes, Paneth cells, DCs	NA	Q9HC29.fasta	Q9HC29	1040	RIP2-IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1954	Beta glucans Click for more detail	Candida albicans(fungi)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	Glucan	Natural	Activation of CLEC7A	CLEC7A	C type Lectin (CTL/CLR)	Human	NA	NA	Q9BXN2.fasta	Q9BXN2	247	critical functions in host defense against Candida albicans invasion	NA	28824166	2017	Pubchem_assay
PRRID_1954	Beta glucans Click for more detail	Candida albicans(fungi)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	Glucan	Natural	Activation of CLEC7A	CLEC7A	C type Lectin (CTL/CLR)	Human	NA	NA	Q9BXN2.fasta	Q9BXN2	247	critical functions in host defense against Candida albicans invasion	NA	28824166	2017	Pubchem_assay
PRRID_1955	beta-1,3-linked Click for more detail	Fungi	NA	NA	NA	Natural	NA	CLEC7A	C type Lectin (CTL/CLR)	Human	NA	C-Type Lectin Domain Family 7, Member A,	Q9BXN2.fasta	Q9BXN2	247	NA	NA	29066255	2017	Pubchem_assay
PRRID_1955	beta-1,3-linked Click for more detail	Fungi	NA	NA	NA	Natural	NA	CLEC7A	C type Lectin (CTL/CLR)	Human	NA	C-Type Lectin Domain Family 7, Member A,	Q9BXN2.fasta	Q9BXN2	247	NA	NA	29066255	2017	Pubchem_assay
PRRID_1956	beta-1,6-linked glucans Click for more detail	Fungi	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	NA	Natural	NA	CLEC7A	C type Lectin (CTL/CLR)	Human	NA	NA	Q9BXN2.fasta	Q9BXN2	247	NA	NA	29066255	2017	Pubchem_assay
PRRID_1956	beta-1,6-linked glucans Click for more detail	Fungi	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)O	NA	NA	Natural	NA	CLEC7A	C type Lectin (CTL/CLR)	Human	NA	NA	Q9BXN2.fasta	Q9BXN2	247	NA	NA	29066255	2017	Pubchem_assay
PRRID_1964	Bropirimine Click for more detail	NA	C1=CC=C(C=C1)C2=C(C(=O)N=C(N2)N)Br	NA	NA	Natural	Induce production of inflammatory cytokines	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	Q9NYK1.fasta	Q9NYK1	1049	NA	NA	29028369	2017	Pubchem_assay
PRRID_1964	Bropirimine Click for more detail	NA	C1=CC=C(C=C1)C2=C(C(=O)N=C(N2)N)Br	NA	NA	Natural	Induce production of inflammatory cytokines	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	Q9NYK1.fasta	Q9NYK1	1049	NA	NA	29028369	2017	Pubchem_assay
PRRID_1966	C. albicans Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1966	C. albicans Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1968	CBLB502 Click for more detail	Salmonella flagellin (Bacteria)	NA	NA	NA	Natural	direct radioprotective effect in vitro via anti-apoptosis and promotes cell cycle recovery	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	HEK293-N-T cells	Leucine-rich Repeat (LRR) Domain	O60602.fasta	O60602	858	NA	Real-time PCR	28407032	2017	Pubchem_assay
PRRID_1968	CBLB502 Click for more detail	Salmonella flagellin (Bacteria)	NA	NA	NA	Natural	direct radioprotective effect in vitro via anti-apoptosis and promotes cell cycle recovery	Toll-like receptor 5 (TLR5)	Toll-like receptor (TLR)	Human	HEK293-N-T cells	Leucine-rich Repeat (LRR) Domain	O60602.fasta	O60602	858	NA	Real-time PCR	28407032	2017	Pubchem_assay
PRRID_1975	Chitin Click for more detail	protozoa, fungi, arthropods, and nematodes (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Chitin induces cy- tokine production, leukocyte recruitment, and alternative mac- rophage activation	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Lungs and gut	TIR domain	O60603.fasta	O60603	784	Activate immune cells to induce cytokine production	NA	28251581	2017	Pubchem_assay
PRRID_1975	Chitin Click for more detail	protozoa, fungi, arthropods, and nematodes (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Chitin induces cy- tokine production, leukocyte recruitment, and alternative mac- rophage activation	Toll-like receptor 2 (TLR2)	Toll-like receptor (TLR)	Human	Lungs and gut	TIR domain	O60603.fasta	O60603	784	Activate immune cells to induce cytokine production	NA	28251581	2017	Pubchem_assay
PRRID_1976	Chitin Click for more detail	protozoa, fungi, arthropods, and nematodes (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Chitin induces cy- tokine production, leukocyte recruitment, and alternative mac- rophage activation	Dectin-1	C type Lectin (CTL/CLR)	Human	Lungs and gut	NA	NA	NA	NA	Activate immune cells to induce cytokine production	NA	28251581	2017	NA
PRRID_1976	Chitin Click for more detail	protozoa, fungi, arthropods, and nematodes (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Chitin induces cy- tokine production, leukocyte recruitment, and alternative mac- rophage activation	Dectin-1	C type Lectin (CTL/CLR)	Human	Lungs and gut	NA	NA	NA	NA	Activate immune cells to induce cytokine production	NA	28251581	2017	NA
PRRID_1978	Cholesterol crystal Click for more detail	Endogenous (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	VEGQ motif	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1978	Cholesterol crystal Click for more detail	Endogenous (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	VEGQ motif	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1979	Chromatin-IgG complexes Click for more detail	NA	NA	NA	NA	Natural	NA	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	lymphoid tissue	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	NA	NA	29028369	2017	Pubchem_assay
PRRID_1979	Chromatin-IgG complexes Click for more detail	NA	NA	NA	NA	Natural	NA	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	lymphoid tissue	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	NA	NA	29028369	2017	Pubchem_assay
PRRID_1980	Chromogranin A Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	activate microglial cells	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Activate NF-KB	NA	28049142	2017	NA
PRRID_1980	Chromogranin A Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	activate microglial cells	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	NA	NA	NA	Activate NF-KB	NA	28049142	2017	NA
PRRID_1981	Chromogranin A Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	activate microglial cells	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	NA	NA	Q96P20.fasta	Q96P20	1036	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1981	Chromogranin A Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	activate microglial cells	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	NA	NA	Q96P20.fasta	Q96P20	1036	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1982	Chromogranin A Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	activate microglial cells	RAGE	Receptor for advanced glycation endproducts (RAGE)	Human	NA	NA	Q15109.fasta	Q15109	404	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1982	Chromogranin A Click for more detail	All vertebrates(others)	NA	NA	Damage-associated molecular patterns (DAMPs)	Natural	activate microglial cells	RAGE	Receptor for advanced glycation endproducts (RAGE)	Human	NA	NA	Q15109.fasta	Q15109	404	Activate NF-KB	NA	28049142	2017	Pubchem_assay
PRRID_1983	CL075 Click for more detail	SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)	CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N	NA	Pattern-associated molecular patterns (PAMPs)	Synthetic	Z-loop proteolytic cleavage, and receptor dimer conformational change	Toll-like receptor 8 (TLR8)	Toll-like receptor (TLR)	Human	Endosomes. Monocytes, macrophages and cDCs	Leucine-rich Repeat (LRR) Domain	Q9NR97.fasta	Q9NR97	1041	MyD88-IRAK4/ IRAK1-IRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1983	CL075 Click for more detail	SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)	CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N	NA	Pattern-associated molecular patterns (PAMPs)	Synthetic	Z-loop proteolytic cleavage, and receptor dimer conformational change	Toll-like receptor 8 (TLR8)	Toll-like receptor (TLR)	Human	Endosomes. Monocytes, macrophages and cDCs	Leucine-rich Repeat (LRR) Domain	Q9NR97.fasta	Q9NR97	1041	MyD88-IRAK4/ IRAK1-IRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1984	CL097 Click for more detail	SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)	CCOCC1=NC2=C(N1)C(=NC3=CC=CC=C32)N	NA	Nucleic Acid	Synthetic	Z-loop proteolytic cleavage, and receptor dimer conformational change	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	Endosomes. pDCs and B cells	Leucine-rich Repeat (LRR) Domain	Q9NYK1.fasta	Q9NYK1	1049	MyD88-IRAK4/ IRAK1-IRF7. MyD88-IRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1984	CL097 Click for more detail	SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)	CCOCC1=NC2=C(N1)C(=NC3=CC=CC=C32)N	NA	Nucleic Acid	Synthetic	Z-loop proteolytic cleavage, and receptor dimer conformational change	Toll-like receptor 7 (TLR7)	Toll-like receptor (TLR)	Human	Endosomes. pDCs and B cells	Leucine-rich Repeat (LRR) Domain	Q9NYK1.fasta	Q9NYK1	1049	MyD88-IRAK4/ IRAK1-IRF7. MyD88-IRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1985	CL097 Click for more detail	SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)	CCOCC1=NC2=C(N1)C(=NC3=CC=CC=C32)N	NA	Nucleic Acid	Synthetic	Z-loop proteolytic cleavage, and receptor dimer conformational change	Toll-like receptor 8 (TLR8)	Toll-like receptor (TLR)	Human	Endosomes. Monocytes, macrophages and cDCs	Leucine-rich Repeat (LRR) Domain	Q9NR97.fasta	Q9NR97	1041	MyD88-IRAK4/ IRAK1-IRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1985	CL097 Click for more detail	SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)	CCOCC1=NC2=C(N1)C(=NC3=CC=CC=C32)N	NA	Nucleic Acid	Synthetic	Z-loop proteolytic cleavage, and receptor dimer conformational change	Toll-like receptor 8 (TLR8)	Toll-like receptor (TLR)	Human	Endosomes. Monocytes, macrophages and cDCs	Leucine-rich Repeat (LRR) Domain	Q9NR97.fasta	Q9NR97	1041	MyD88-IRAK4/ IRAK1-IRAF6- IKKs-NF-jB	NA	28374903	2017	Pubchem_assay
PRRID_1986	Cladophialophora carrionii Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1986	Cladophialophora carrionii Click for more detail	NA	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1987	CpG motif Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	human peripheral B¬≠lymphocytes	NA	Q96P20.fasta	Q96P20	1036	NA	NA	29170665	2017	Pubchem_assay
PRRID_1987	CpG motif Click for more detail	NA	NA	NA	Protein	Natural	NA	Nod-like receptor P3 (NLRP3)	NOD-like receptor (NLR)	Human	human peripheral B¬≠lymphocytes	NA	Q96P20.fasta	Q96P20	1036	NA	NA	29170665	2017	Pubchem_assay
PRRID_1988	CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	Oral carcinogenesis	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	squamous cell carcinomas	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	interferon-Œ≤ production and activation of caspases 3 and 9	NA	28982847	2017	Pubchem_assay
PRRID_1988	CpG-ODN Click for more detail	Bacteria	NA	NA	Nucleic Acid	Synthetic	Oral carcinogenesis	Toll-like receptor 9 (TLR9)	Toll-like receptor (TLR)	Human	squamous cell carcinomas	Leucine-rich Repeat (LRR) Domain	Q9NR96.fasta	Q9NR96	1032	interferon-Œ≤ production and activation of caspases 3 and 9	NA	28982847	2017	Pubchem_assay
PRRID_1992	Cytosolic double-stranded DNA Click for more detail	NA	NA	NA	NA	Natural	NA	AIM2	Pattern recognition receptor (PRR)	Human	NA	NA	O14862.fasta	O14862	343	NA	NA	29066255	2017	Pubchem_assay
PRRID_1992	Cytosolic double-stranded DNA Click for more detail	NA	NA	NA	NA	Natural	NA	AIM2	Pattern recognition receptor (PRR)	Human	NA	NA	O14862.fasta	O14862	343	NA	NA	29066255	2017	Pubchem_assay
PRRID_1993	d-lactoyl-l-Ala-d-Glu-meso-DAP-l-Gly Click for more detail	NA	NA	NA	Agonist	Synthetic	Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-Œ∫B-mediated expression of inflammatory cytokines	Nod-like receptor C1 (NLRC1)	NOD-like receptor (NLR)	Human	Intracellular	C-terminal leucine-rich regions and NOD domains	NA	NA	NA	triggering production of Œ≤-defensins via an NF-Œ∫B signaling pathway	NA	28776416	2017	NA
PRRID_1993	d-lactoyl-l-Ala-d-Glu-meso-DAP-l-Gly Click for more detail	NA	NA	NA	Agonist	Synthetic	Agonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-Œ∫B-mediated expression of inflammatory cytokines	Nod-like receptor C1 (NLRC1)	NOD-like receptor (NLR)	Human	Intracellular	C-terminal leucine-rich regions and NOD domains	NA	NA	NA	triggering production of Œ≤-defensins via an NF-Œ∫B signaling pathway	NA	28776416	2017	NA
PRRID_1994	Dead cells Click for more detail	Endogenous (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay
PRRID_1994	Dead cells Click for more detail	Endogenous (others)	NA	NA	Pattern-associated molecular patterns (PAMPs)	Natural	Immunostimulant	Mincle(Clec4e)	Syk-coupled CLR	Human	NA	NA	Q9ULY5.fasta	Q9ULY5	219	Protective role in infection model	NA	28167651	2017	Pubchem_assay

previous 1 2...13 14 151617 18 19...43 44 next