Primary information |
---|
PRRID | PRRID_1983 |
Ligand Name | CL075 |
Source | SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)
|
Sequence of ligand | CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Synthetic |
Role of Ligand | Z-loop proteolytic cleavage, and receptor dimer conformational change |
Name of receptor | Toll-like receptor 8 (TLR8) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Endosomes. Monocytes, macrophages and cDCs |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | Q9NR97.fasta |
Swiss prot ID | Q9NR97 |
Length Of Receptor | 1041 |
Function | MyD88-IRAK4/ IRAK1-IRAF6- IKKs-NF-jB |
Assay used | NA |
PMID | 28374903 |
Year of Publication | 2017 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1983 |
Ligand Name | CL075 |
Source | SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus)
|
Sequence of ligand | CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N |
Length | NA |
Type | Pattern-associated molecular patterns (PAMPs) |
Occurence | Synthetic |
Role of Ligand | Z-loop proteolytic cleavage, and receptor dimer conformational change |
Name of receptor | Toll-like receptor 8 (TLR8) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Endosomes. Monocytes, macrophages and cDCs |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | Q9NR97.fasta |
Swiss prot ID | Q9NR97 |
Length Of Receptor | 1041 |
Function | MyD88-IRAK4/ IRAK1-IRAF6- IKKs-NF-jB |
Assay used | NA |
PMID | 28374903 |
Year of Publication | 2017 |
Pubchem assay | Pubchem_assay |