Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_380 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMCH-1 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration0.01 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_381 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMC-1 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration0.01 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_382 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMBC | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration0.01 MOI | In-vitro result90% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_383 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMCH-1 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration0.1 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_384 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMC-1 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration0.1 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_385 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMBC | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration0.1 MOI | In-vitro result48% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_386 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMCH-1 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration1 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_387 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMC-1 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration1 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_388 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMBC | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration1 MOI | In-vitro result20% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_389 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMCH-1 | Concentration of cell line3.0E+3 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration5 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_390 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMC-1 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration5 MOI | In-vitro result13% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_391 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman cholangiocarcinoma cell line | Cell lineKMBC | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayDojindo cell counting kit | In-vitro virus concentration5 MOI | In-vitro result20% cancer cell viability on 7 day | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_392 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHomozygous athymic female nude mice (subcutaneously injected with KMC-1 cells suspended in 50 μl Matrigel) | In-vivo virus concentration1.0E+7 PFU | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to 30 cubic millimeter compared to control 200 cubic millimeter after 15 days | Mode of deliveryIntratumorally | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26584530 |
IDOV_727 | Virus nameVaccinia virus | Virus strainVV-Onco | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationThe viral thymidine kinase (TK) gene is insertionally inactivated | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineMHCC97-H | Concentration of cell line5000 to 7000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cancer cell viability at 96 hours post-infection | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27441866 |
IDOV_728 | Virus nameVaccinia virus | Virus strainVV-Onco | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationThe viral thymidine kinase (TK) gene is insertionally inactivated | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineMHCC97-H | Concentration of cell line5000 to 7000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result50% cancer cell viability at 96 hours post-infection | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27441866 |
IDOV_1907 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1908 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1909 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1910 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell death after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1911 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result50% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1912 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result25% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1913 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result5% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1914 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell line1.0E+6 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result100% cell death after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_1915 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMalignan small cell canine carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for MTH52c cell line | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultSignificant decrease in tumor volume after 42 days | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus cause increase expression of ApoA1, IL-2,11,18,IFN-gamma, IP-10, MCP-1,3,5,MIP-2,MMP-9 and TNF alpha | Clinical trialNA | PMID20631910 |
IDOV_2047 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2048 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2049 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2050 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result22% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2051 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result90% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2052 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result58% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2053 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survial after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2054 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result22% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2055 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2056 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result80% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2057 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2058 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2059 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2060 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2061 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2062 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2063 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell linePLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismAthymic hsd nude mice xenograft for PLC cell line | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityReduction in tumor volume below 2000mm compared to control after 45 days | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2064 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineHuh-7 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismAthymic hsd nude mice xenograft for PLC cell line | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityReduction in tumor volume below 3000mm compared to control after 35 days | In-vivo result | Mode of deliveryNA | Pathway inducedInduction of apoptosis in cancer cell line | Immunogenic effectIncreased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 | Clinical trialNA | PMID21779374 |
IDOV_2412 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2413 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2414 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2415 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result50% cell killing after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2416 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result40% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2417 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2418 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2419 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result90% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2420 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result20% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2421 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell killing after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2422 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2423 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2424 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2425 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2426 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2427 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2428 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2429 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2430 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result50% cell killing after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2431 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result60% cell killing after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2432 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2433 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2434 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2435 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result50% cell killing after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2436 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman mesothelia cell line | Cell lineMSTO-211 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result60% cell killing after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2437 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2438 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2439 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result90% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2440 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result90% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2441 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineH1650 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result80% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2442 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2443 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2444 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2445 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2446 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast cancer cell line | Cell lineMDA-MB-231 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2447 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2448 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2449 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result90% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2450 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result60% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2451 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman thyroid cancer cell line | Cell line8505c | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result10% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2452 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2453 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2454 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2455 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result70% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2456 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal cancer cell line | Cell lineHCT-8 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result30% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2457 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2458 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2459 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result50% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2460 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result10% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2461 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman pancreatic cancer cell line | Cell linePANC-1 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell death after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2462 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2463 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2464 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2465 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2466 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric cancer cell line | Cell lineMKN-45 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result80% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2467 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2468 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2469 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result50% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |