| Primary information |
|---|
| OV_ID | OV_392 |
| Virus Name | Vaccinia virus |
| Strain | GLV-1h68 |
| Virus type | DNA |
| Virus family | Poxviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | NA |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | Homozygous athymic female nude mice (subcutaneously injected with KMC-1 cells suspended in 50 μl Matrigel) |
| In-vivo virus concentration | 1 × 10ⷠPFU |
| In-vivo toxicity | NA |
| In-vivo result | Reduction in tumor volume to 30 cubic millimeter compared to control 200 cubic millimeter after 15 days |
| Mode of delivery | Intratumorally |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 26584530 |