Detailed description page of Selected OV_ID


OV_392 details
Primary information
OV_IDOV_392
Virus Name Vaccinia virus
StrainGLV-1h68
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismHomozygous athymic female nude mice (subcutaneously injected with KMC-1 cells suspended in 50 μl Matrigel)
In-vivo virus concentration1 × 10⁷ PFU
In-vivo toxicityNA
In-vivo resultReduction in tumor volume to 30 cubic millimeter compared to control 200 cubic millimeter after 15 days
Mode of deliveryIntratumorally
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26584530