| Primary information |
|---|
| OV_ID | OV_2055 |
| Virus Name | Vaccinia virus |
| Strain | GLV-1h68 |
| Virus type | DNA |
| Virus family | Poxviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Human hepatocellular carcinoma cell line |
| Cell line | PLC |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 0.1 MOI |
| In-vitro result | 100% cell survival after 24 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Induction of apoptosis in cancer cell line |
| Immunogenic effect | Increased expression of immunological gene such as GM-CSF, IFN-gamma, IL-6,2,12,18, IP-10, MCP-1,3,5, TNF-alpha and MIP-2 |
| Clinical trial | NA |
| PMID | 21779374 |