| Primary information |
|---|
| OV_ID | OV_728 |
| Virus Name | Vaccinia virus |
| Strain | VV-Onco |
| Virus type | DNA |
| Virus family | Poxviridae |
| Modification in virus genome | The viral thymidine kinase (TK) gene is insertionally inactivated |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China |
| Origin of cell line | Human hepatocellular carcinoma cell line |
| Cell line | MHCC97-H |
| Concentration of cell line | 5 |
| In-vitro toxicity | NA |
| Assay | MTT assay |
| In-vitro virus concentration | 10 MOI |
| In-vitro result | 50% cancer cell viability at 96 hours post-infection |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 27441866 |