Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4953Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.1 MOI40% cell viabilityNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4954Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.01 MOI60% cell viabilityNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4955Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay10 MOI40% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4956Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay1 MOI60% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4957Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.1 MOI70% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4958Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.01 MOI80% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4959Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay10 MOI70% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4960Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay1 MOI80% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4961Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.1 MOI90% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4962Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.01 MOI90% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4963Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay10 MOI20% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4964Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay1 MOI50% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4965Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.1 MOI60% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4966Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.01 MOI80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4967Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay10 MOI60% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4968Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay1 MOI70% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4969Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.1 MOI100% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4970Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionHuman lung cancer cell lineA549NANAMTT assay0.01 MOI100% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4971Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay2 MOI60% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4972Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay5 MOI40% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4973Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay2 MOI20% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4974Vaccinia viruswild typeDNAPoxviridaeNoneYesNoNoShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay5 MOI5% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4975Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay2 MOI44% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4976Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay5 MOI35% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4977Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay2 MOI20% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4978Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneShanghai cell collectionLewis lung cancer cell lineLLCNANAMTT assay5 MOI2% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA27208781
OV_4979Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneNANANANANANANANAC54BL/6 mice xenograft for A549 cell line (5.0E+6)1.0E+7 pfuNA Reduction in tumor volume to 1000 cubic mm compared to control 2200 cubic mm after 27 daysIntratumoralInduction of apoptosisNANA27208781
OV_4980Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneNANANANANANANANAImmunocompetant mice xenograft for LLC1.0E+7 pfuNA Reduction in tumor volume to 5000 cubic mm compared to control 10000 cubic mm after 15 daysIntratumoralInduction of apoptosisNANA27208781
OV_5007Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay0.1 MOI35% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5008Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay1 MOI22% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5009Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5010Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay0.1 MOI36% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5011Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay1 MOI24% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5012Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5013Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay0.1 MOI35% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5014Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay1 MOI22% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5015Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine melanoma cell lineB161.0E+4 cells per wellNAMTT assay10 MOI18% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5016Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay0.1 MOI55% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5017Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay1 MOI42% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5018Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay10 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5019Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay0.1 MOI58% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5020Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay1 MOI44% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5021Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay10 MOI40% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5022Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay0.1 MOI58% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5023Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay1 MOI46% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5024Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman lung cancer cell lineA5491.0E+4 cells per wellNAMTT assay10 MOI40% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5025Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay0.1 MOI68% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5026Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay1 MOI36% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5027Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay10 MOI26% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5028Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay0.1 MOI68% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5029Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay1 MOI40% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5030Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5031Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay0.1 MOI65% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5032Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay1 MOI36% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5033Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman gastric carcinoma cell lineSCG-79011.0E+4 cells per wellNAMTT assay10 MOI22% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5034Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay0.1 MOI50% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5035Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay1 MOI40% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5036Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay10 MOI25% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5037Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay0.1 MOI52% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5038Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay1 MOI38% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5039Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay10 MOI25% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5040Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay0.1 MOI51% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5041Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay1 MOI38% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5042Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCMurine hepatoma cell lineHepal-61.0E+4 cells per wellNAMTT assay10 MOI21% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5043Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI40% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5044Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5045Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5046Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5047Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5048Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5049Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay0.1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5050Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay1 MOI30% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5051Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman breast adenocarcinoma cell lineMDA-MB-2311.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5052Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay0.1 MOI50% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5053Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay1 MOI35% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5054Vaccinia virusVG9DNAPoxviridaeNoneYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay10 MOI20% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5055Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay0.1 MOI50% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5056Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay1 MOI35% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5057Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay10 MOI22% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5058Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay0.1 MOI50% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5059Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay1 MOI35% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5060Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoATCCHuman hepatocellular carcinoma cell lineSMMC77211.0E+4 cells per wellNAMTT assay10 MOI21% cell viability after 3 daysNoNoNA No responseNANANANA28465492
OV_5061Vaccinia virusVG9-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoNANANANANANANANAC56BL/6 mice xenograft for SMMC-7721 (1.0E+6 cells )1.0E+7 pfuNA Prolongs the survival timeIntratumoralNANANA28465492
OV_5062Vaccinia virusWR-EGFPDNAPoxviridaeAddition of EGFP gene in tk locusYesNoNoNANANANANANANANAC56BL/6 mice xenograft for SMMC-7721 (1.0E+6 cells )1.0E+7 pfuNA Prolongs the survival timeIntratumoralNANANA28465492
OV_5092Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay0.001 MOI70% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5093Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay0.01 MOI50% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5094Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay0.1 MOI20% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5095Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5096Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay0.001 MOI70% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5097Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay0.01 MOI60% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5098Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay0.1 MOI40% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5099Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineHS294T1.0E+4 cells per wellNAMTS assay1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5100Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay0.001 MOI60% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5101Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay0.01 MOI30% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5102Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay0.1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5103Vaccinia virusvvdd-tdTomato-hDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of human DAIYesNoVirus expressing human DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay1 MOI100% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5104Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay0.001 MOI80% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5105Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay0.01 MOI30% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5106Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay0.1 MOI10% cell viabilityNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058
OV_5107Vaccinia virusvvdd-tdTomato-mDAIDNAPoxviridaeDeletion of tk gene and vaccinia growth gene and addition of murine DAIYesNoVirus expressing murine DAI geneATCCHuman melanoma cell lineA20581.0E+4 cells per wellNAMTS assay1 MOI100% cell killingNoNoNA No responseNANAInduction of Immunogenic gene such as T cell activationNA27626058