Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_4953 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4954 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4955 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4956 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result60% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4957 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4958 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4959 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4960 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result80% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4961 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4962 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4963 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4964 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4965 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4966 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4967 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4968 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4969 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4970 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4971 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result60% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4972 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result40% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4973 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result20% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4974 | Virus nameVaccinia virus | Virus strainwild type | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result5% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4975 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result44% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4976 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result35% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4977 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration2 MOI | In-vitro result20% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4978 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineLewis lung cancer cell line | Cell lineLLC | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result2% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4979 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismC54BL/6 mice xenograft for A549 cell line (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to 1000 cubic mm compared to control 2200 cubic mm after 27 days | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4980 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismImmunocompetant mice xenograft for LLC | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to 5000 cubic mm compared to control 10000 cubic mm after 15 days | Mode of deliveryIntratumoral | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_5007 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result35% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5008 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result22% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5009 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5010 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result36% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5011 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result24% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5012 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5013 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result35% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5014 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result22% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5015 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine melanoma cell line | Cell lineB16 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result18% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5016 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result55% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5017 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result42% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5018 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5019 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result58% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5020 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result44% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5021 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5022 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result58% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5023 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result46% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5024 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5025 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result68% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5026 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result36% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5027 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result26% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5028 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result68% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5029 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5030 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5031 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result65% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5032 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result36% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5033 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman gastric carcinoma cell line | Cell lineSCG-7901 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result22% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5034 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5035 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5036 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result25% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5037 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result52% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5038 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result38% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5039 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result25% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5040 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result51% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5041 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result38% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5042 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineMurine hepatoma cell line | Cell lineHepal-6 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result21% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5043 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5044 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5045 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5046 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5047 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5048 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5049 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5050 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5051 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman breast adenocarcinoma cell line | Cell lineMDA-MB-231 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5052 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5053 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result35% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5054 | Virus nameVaccinia virus | Virus strainVG9 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5055 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5056 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result35% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5057 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result22% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5058 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5059 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result35% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5060 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman hepatocellular carcinoma cell line | Cell lineSMMC7721 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result21% cell viability after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5061 | Virus nameVaccinia virus | Virus strainVG9-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismC56BL/6 mice xenograft for SMMC-7721 (1.0E+6 cells ) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultProlongs the survival time | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5062 | Virus nameVaccinia virus | Virus strainWR-EGFP | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationAddition of EGFP gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismC56BL/6 mice xenograft for SMMC-7721 (1.0E+6 cells ) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultProlongs the survival time | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID28465492 |
IDOV_5092 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5093 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5094 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5095 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5096 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5097 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5098 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5099 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineHS294T | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5100 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result60% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5101 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5102 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5103 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-hDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of human DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing human DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5104 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.001 MOI | In-vitro result80% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5105 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.01 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5106 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |
IDOV_5107 | Virus nameVaccinia virus | Virus strainvvdd-tdTomato-mDAI | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of tk gene and vaccinia growth gene and addition of murine DAI | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing murine DAI gene | Source of cell lineATCC | Origin of cell lineHuman melanoma cell line | Cell lineA2058 | Concentration of cell line1.0E+4 cells per well | In-vitro toxicityNA | AssayMTS assay | In-vitro virus concentration1 MOI | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduction of Immunogenic gene such as T cell activation | Clinical trialNA | PMID27626058 |