Detailed description page of Selected OV_ID


OV_5061 details
Primary information
OV_IDOV_5061
Virus Name Vaccinia virus
StrainVG9-EGFP
Virus typeDNA
Virus familyPoxviridae
Modification in virus genomeAddition of EGFP gene in tk locus
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismC56BL/6 mice xenograft for SMMC-7721 (10⁶ cells )
In-vivo virus concentration1 × 10⁷ PFU
In-vivo toxicityNA
In-vivo resultProlongs the survival time
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID28465492