Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_338AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNACrystal violet staining10 MOI92% cancer cell deathNoNoNA No responseNANANANA26561948
OV_339AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineCalu12.5E+4 cells per wellNACrystal violet staining10 MOI20% cancer cell deathNoNoNA No responseNANANANA26561948
OV_340AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineH4412.5E+4 cells per wellNACrystal violet staining10 MOI2% cancer cell deathNoNoNA No responseNANANANA26561948
OV_341AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineH-12992.5E+4 cells per wellNACrystal violet staining20 MOI100% cancer cell deathNoNoNA No responseNANANANA26561948
OV_342AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNACrystal violet staining20 MOI100% cancer cell deathNoNoNA No responseNANANANA26561948
OV_343AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineCalu12.5E+4 cells per wellNACrystal violet staining20 MOI80% cancer cell deathNoNoNA No responseNANANANA26561948
OV_344AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineH4412.5E+4 cells per wellNACrystal violet staining20 MOI45% cancer cell deathNoNoNA No responseNANANANA26561948
OV_345AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI58% cancer cell viabilityNoNoNA No responseNANANANA26561948
OV_346AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoATCCHuman lung cancer cell lineH4412.5E+4 cells per wellNAMTT assay10 MOI62% cancer cell viabilityNoNoNA No responseNANANANA26561948
OV_347AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantYesNoNoATCCHuman lung cancer cell lineCalu12.5E+4 cells per wellNAMTT assay10 MOI74% cancer cell viabilityNoNoNA No responseNANANANA26561948
OV_348AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) - 0.6 mMNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay2.5 MOI18% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagyNANA26561948
OV_349AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) - 0.75 mMNoATCCHuman lung cancer cell lineH4412.5E+4 cells per wellNAMTT assay20 MOI22% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagyNANA26561948
OV_350AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) - 1 mMNoATCCHuman lung cancer cell lineCalu12.5E+4 cells per wellNAMTT assay10 MOI12% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagyNANA26561948
OV_351AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI49% cancer cell viabilityNoNoNA No responseNANANANA26561948
OV_352AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI26% cancer cell viabilityNoNoNA No responseNANANANA26561948
OV_353AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) and 3-MA at -0.75 mM and 10 mM concentration, respectivelyNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI62% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagy (Autophagy effect slightly inhibited by 3-MA)NANA26561948
OV_354AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) and 3-MA at -0.75 mM and 10 mM concentration, respectivelyNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI44% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagy (Autophagy effect slightly inhibited by 3-MA)NANA26561948
OV_355AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) and BAF-A1 at -0.75 mM and 10 nM concentration, respectivelyNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI65% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagy (Autophagy effect slightly inhibited by Baf-A1)NANA26561948
OV_356AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) and BAF-A1 at -0.75 mM and 10 nM concentration, respectivelyNoATCCHuman lung cancer cell lineA5492.5E+4 cells per wellNAMTT assay10 MOI47% cancer cell viabilityNoNoNA No responseNAJNK activation induces autophagy (Autophagy effect slightly inhibited by Baf-A1)NANA26561948
OV_357AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantYesNoNoNANANANANANANANAAthymic BALB/c nu/nu male mice (subcutaneously injected A549 lung cancer cells, 5.0E+6 cells)1.0E+9 pfu (every 3 days for at total 4 treatments)NA 41% smaller tumor size compared to the negative control virus AdLacZIntratumorallyNANANA26561948
OV_358AdenovirusAdhz60DNAAdenoviridaeE1b-deleted mutantNoVirus in combination with temozolomide (TMZ) intraperitoneally at 50 mg/Kg for five consecutive daysNoNANANANANANANANAAthymic BALB/c nu/nu male mice (subcutaneously injected A549 lung cancer cells, 5.0E+6 cells)1.0E+9 pfu (every 3 days for at total 4 treatments)NA 70% smaller tumor size compared to the negative control virus AdLacZIntratumorallyJNK activation induces autophagyNANA26561948
OV_359AdenovirusAdLacZDNAAdenoviridaeE1/E3-deleted mutantNoVirus in combination with temozolomide (TMZ) intraperitoneally at 50 mg/Kg for five consecutive daysNoNANANANANANANANAAthymic BALB/c nu/nu male mice (subcutaneously injected A549 lung cancer cells, 5.0E+6 cells)1.0E+9 pfu (every 3 days for at total 4 treatments)NA 30% smaller tumor size compared to the negative control virus AdLacZIntratumorallyJNK activation induces autophagyNANA26561948
OV_402AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI110% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_403AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_404AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI118% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_405AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI39% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_406AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI98% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_407AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI42% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_408AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI78% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_409AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_410AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI30% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_411AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_412AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_413AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_414AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI35% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_415AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI35% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_416AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI24% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_417AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_418AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_419AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI21% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_420AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_421AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_422AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI12% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_423AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_424AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI8% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_425AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).YesNoIL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI12% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_426AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI110% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_427AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI50% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_428AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI130% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_429AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI50% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_430AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI116% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_431AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI51% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_432AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI100% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_433AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_434AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI50% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_435AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_436AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman cervical squamous cell carcinoma cell lineOV-43.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_437AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovarian serous adenocarcinoma cell lineOVCAR33.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI40% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_438AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI88% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_439AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI46% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_440AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI62% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_441AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_442AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI26% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_443AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI22% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_444AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI24% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_445AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_446AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_447AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_448AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_449AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneYesNoNoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_450AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI90% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_451AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI58% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_452AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI74% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_453AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI22% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_454AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI28% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_455AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_456AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_457AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_458AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_459AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_460AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_461AdenovirusCRAd-ING4 (Ad5/3Δ24cmvING4)DNAAdenoviridaeViral mutanat with CMVp-driven Inhibitor of Growth 4 (ING4) geneNoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)NoATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_462AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI56% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_463AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI58% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_464AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI24% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_465AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_466AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_467AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_468AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_469AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)11 MOI19% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_470AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_471AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)33 MOI16% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_472AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI14% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_473AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with CRAd (a deletion adenovirus mutant of 24 nucleotides (Δ24) in the E1A gene)IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)100 MOI12% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_474AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with ING4IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI30% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_475AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with ING4IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)0.4 MOI38% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_476AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with ING4IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI22% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_477AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with ING4IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)1 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_478AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with ING4IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3ip.1 OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI20% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517
OV_479AdenovirusCRAd-IL24 (Ad5/3Δ24cmvIL24)DNAAdenoviridaeViral mutanat with IL-24 gene incorporated in place of the deleted E3B region (ΔE3B) under transcriptional control of the human CMV promoter (CMVp).NoViral starin in combination with ING4IL-24 gene incorporated in place of the deleted E3B regionATCCHuman ovary cancer cell lineSKOV3luc OvCa3.0E+5 to 5.0E+5 cells per wellToxic to normal ovarian surface epithelial IOSE-120 and IOSE-523 cellsMTS-based Cell Proliferation Assay (Promega)4 MOI18% cancer cell viability (percentages are calculated with respect to mock-infected cell monolayers)NoNoNA No responseNANANANA27349517