Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1691Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineOS-RC-22.0E+4 cells per wellNAMTT assay0.1 MOI75% cell survival after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1692Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineOS-RC-22.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1693Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineOS-RC-22.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1694Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineOS-RC-22.0E+4 cells per wellNAMTT assay0.1 MOI60% cell survival after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1695Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineOS-RC-22.0E+4 cells per wellNAMTT assay0.1 MOI60% cell survival after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1696Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineOS-RC-22.0E+4 cells per wellNAMTT assay0.1 MOI60% cell survival after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1697Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1698Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1699Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1700Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI85% cell survival after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1701Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI85% cell survival after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1702Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1703Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1704Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1705Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI85% cell survival after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1706Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI85% cell survival after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1707Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1708Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1709Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI90% cell survival after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1710Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI75% cell survival after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1711Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineT52.0E+4 cells per wellNAMTT assay0.1 MOI75% cell survival after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1712Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1713Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1714Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1715Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1716Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1717Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1718Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1719Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1720Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1721Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1722Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 24 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1723Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 48 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1724Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 72 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1725Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 96 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1726Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNAHuman renal cell carcinoma cell lineBJ-12.0E+4 cells per wellNAMTT assay0.1 MOINo significant cell death after 120 hoursNoNoNA No responseNAVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1727Measles virusMV-Edm strainRNAParamyxoviridaeMV-NPL virus , addition of P, N and L geneYesNoNoNANANANANANANANABALB/c nude mice xenograft for A-498 cells1.0E+5 pfuNA Survival rate increased in 55% of animalsIntratumoralVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1728Measles virusMV-Edm strainRNAParamyxoviridaeMV-P virus , addition of P geneYesNoNoNANANANANANANANABALB/c nude mice xenograft for A-498 cells1.0E+5 pfuNA Survival rate increased in 11% of animalsIntratumoralVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_1729Measles virusMV-Edm strainRNAParamyxoviridaeMV-Etag virusYesNoNoNANANANANANANANABALB/c nude mice xenograft for A-498 cells1.0E+5 pfuNA No effect on increase in survival timeIntratumoralVirus induce apoptosis in cancer cellsInduce expression of IFN-gamma, an antiviral proteinNA20051938
OV_2665Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.01 MOI100% cell survival after 24 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2666Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.01 MOI100% cell survival after 48 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2667Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.01 MOI100% cell survival after 72 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2668Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.01 MOI100% cell survival after 96 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2669Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2670Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2671Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.1 MOI80% cell survival after 72 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2672Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit0.1 MOI60% cell survival after 96 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2673Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit1 MOI90% cell survival after 24 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2674Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit1 MOI80% cell survival after 48 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2675Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit1 MOI70% cell survival after 72 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2676Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG22.0E+5 cells per wellNACell proliferation assay kit1 MOI50% cell survival after 96 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2677Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.01 MOI100% cell survival after 24 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2678Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.01 MOI100% cell survival after 48 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2679Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.01 MOI90% cell survival after 72 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2680Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.01 MOI80% cell survival after 96 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2681Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.1 MOI100% cell survival after 24 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2682Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2683Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.1 MOI90% cell survival after 72 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2684Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit0.1 MOI70% cell survival after 96 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2685Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit1 MOI100% cell survival after 24 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2686Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit1 MOI80% cell survival after 48 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2687Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit1 MOI70% cell survival after 72 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2688Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHuh-62.0E+5 cells per wellNACell proliferation assay kit1 MOI50% cell survival after 96 hoursNoNoNA No responseNAInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2689Measles virusMV-EdmRNAParamyxoviridaeInsertion of human CEA gene upstream of MV N geneYesNoNoATCCHuman hepatoblastoma cell lineHepG2NANANANANANude mice xenograft for Hep2G (5.0E+6 cell)1.0E+7 TCID50NA Reduction in tumor volume to 300mm after 37 days as compared to control 550mm and increase in survival time above 120 days as compared to control 30 daysIntratumoralInduction of apoptosis in cancerIncrease expression of CD46NA23009685
OV_2844Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman lung cancer cell lineA5491 million cells per wellNACell death detection kit1 MOI28% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2845Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman lung cancer cell lineADK31 million cells per wellNACell death detection kit1 MOI18% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2846Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman lung cancer cell lineADK1171 million cells per wellNACell death detection kit1 MOI28% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2847Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman lung cancer cell lineADK1531 million cells per wellNACell death detection kit1 MOI40% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2848Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman colorectal cancer cell lineCaco-21 million cells per wellNACell death detection kit1 MOI50% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2849Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman colorectal cancer cell lineHT-291 million cells per wellNACell death detection kit1 MOI45% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2850Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman colorectal cancer cell lineSW4801 million cells per wellNACell death detection kit1 MOI40% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2851Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman colorectal cancer cell lineSW6201 million cells per wellNACell death detection kit1 MOI30% cells survivedNoNoNA No responseNAActivation of caspase-3NANA23586034
OV_2852Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman lung cancer cell lineA549NANANANANARJ:NMRI nude mice xenograft for A549 cell line (1.5E+7) 1.0E+6 pfuNA Significant reduction in tumor volume after 42 daysIntratumoralActivation of caspase-3NANA23586034
OV_2853Measles virusAttenuated strainRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureHuman lung cancer cell lineCaco-2NANANANANARJ:NMRI nude mice xenograft for A549 cell line (1.5E+7) 1.0E+6 pfuNA Significant reduction in tumor volume after 31 daysIntratumoralActivation of caspase-3NANA23586034
OV_2897Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineU9375000 cells per wellNALuminiscent cell viability assay1 MOI75% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2900Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineTHP-15000 cells per wellNALuminiscent cell viability assay1 MOI70% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2903Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineHL-605000 cells per wellNALuminiscent cell viability assay1 MOI100% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2906Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineHuT-1205000 cells per wellNALuminiscent cell viability assay1 MOI17% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2909Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineJurkat5000 cells per wellNALuminiscent cell viability assay1 MOI1% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2912Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineMT-15000 cells per wellNALuminiscent cell viability assay1 MOI30% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2915Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineMT-25000 cells per wellNALuminiscent cell viability assay1 MOI4% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2918Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineMT-45000 cells per wellNALuminiscent cell viability assay1 MOI11% cell viabilityNoNoNA No responseNAInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2931Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoLaboratory grown own cultureLeukemia cell lineU937NANANANANABALB/c nude mice xenograft for U9371.0E+5 pfuNA Tumor volume regressed to below 12.5 mm after 14 daysIntratumoralInduction of apoptosis by virus alone and in combinationNANA25193462
OV_2939Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay0.01 MOI90% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2940Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay0.1 MOI90% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2941Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay1 MOI50% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2942Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay10 MOI20% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2943Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay0.01 MOI90% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2944Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay0.1 MOI70% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2945Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay1 MOI40% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2946Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay10 MOI100% cell death after 48 hoursNoNoNA No responseNANANANA25843626
OV_2947Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineST88-141.0E+4 cells per wellNACell titer assay0.01 MOI90% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2948Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineST88-141.0E+4 cells per wellNACell titer assay0.1 MOI70% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2949Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineST88-141.0E+4 cells per wellNACell titer assay1 MOI40% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2950Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineST88-141.0E+4 cells per wellNACell titer assay10 MOI100% cell death after 48 hoursNoNoNA No responseNANANANA25843626
OV_2951Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineHSCIL-11.0E+4 cells per wellNACell titer assay0.01 MOI100% cell death after 48 hoursNoNoNA No responseNANANANA25843626
OV_2952Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineHSCIL-11.0E+4 cells per wellNACell titer assay0.1 MOI100% cell death after 48 hoursNoNoNA No responseNANANANA25843626
OV_2953Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineHSCIL-11.0E+4 cells per wellNACell titer assay1 MOI80% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2954Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineHSCIL-11.0E+4 cells per wellNACell titer assay10 MOI50% cell survival after 48 hoursNoNoNA No responseNANANANA25843626
OV_2955Measles viruswild typeRNAParamyxoviridaeNoneYesNoNoNAHuman malignant peripheral nerve sheath tumor cell lineSTS26T1.0E+4 cells per wellNACell titer assay0.01 MOI90% cell survival after 72 hoursNoNoNA No responseNANANANA25843626