Detailed description page of Selected OV_ID


OV_2931 details
Primary information
OV_IDOV_2931
Virus Name Measles virus
Strainwild type
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineLaboratory grown own culture
Origin of cell lineLeukemia cell line
Cell lineU937
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for U937
In-vivo virus concentration1 × 10⁵ pfu
In-vivo toxicityNA
In-vivo resultTumor volume regressed to below 12.5 mm after 14 days
Mode of deliveryIntratumoral
Pathway inductionInduction of apoptosis by virus alone and in combination
Immunogenic effectNA
Clinical trialNA
PMID25193462