Detailed description page of Selected OV_ID


OV_1729 details
Primary information
OV_IDOV_1729
Virus Name Measles virus
StrainMV-Edm strain
Virus typeRNA
Virus familyParamyxoviridae
Modification in virus genomeMV-Etag virus
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for A-498 cells
In-vivo virus concentration1 × 10⁵ pfu
In-vivo toxicityNA
In-vivo resultNo effect on increase in survival time
Mode of deliveryIntratumoral
Pathway inductionVirus induce apoptosis in cancer cells
Immunogenic effectInduce expression of IFN-gamma, an antiviral protein
Clinical trialNA
PMID20051938