| Primary information |
|---|
| OV_ID | OV_1729 |
| Virus Name | Measles virus |
| Strain | MV-Edm strain |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | MV-Etag virus |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | NA |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | BALB/c nude mice xenograft for A-498 cells |
| In-vivo virus concentration | 1 × 10ⵠpfu
|
| In-vivo toxicity | NA |
| In-vivo result | No effect on increase in survival time |
| Mode of delivery | Intratumoral |
| Pathway induction | Virus induce apoptosis in cancer cells |
| Immunogenic effect | Induce expression of IFN-gamma, an antiviral protein |
| Clinical trial | NA |
| PMID | 20051938 |