The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_842	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	NA	Epithelial ovarian carcinoma	SKOV3	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_843	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	OVCAR3	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_844	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	CaOV3	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_845	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2780	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.01 MOI	35% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_846	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2781	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.1 MOI	75% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_847	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2782	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.1 MOI	75% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_848	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2783	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.1 MOI	75% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_849	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2784	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	0.1 MOI	75% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_850	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2784	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	1 MOI	98% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_851	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2784	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	1 MOI	98% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_852	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2784	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	1 MOI	98% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_853	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	Epithelial ovarian carcinoma	A2784	3.0E+3 cells per well	Minimal cytotoxic to mesothelial cells	Beta galacosidase colorimetric proliferation assay	1 MOI	98% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	10770637
OV_854	Herpes simplex virus	HSV-G207	DNA	Herpesviridae	Deletion mutant in ICP34.5 and ICPC6 gene	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	Female CB17 SCID mice model xenograft for SKOV3 cell	5.0E+6 pfu	NA	Reduction in tumor growth to 50mg compared to control of 300mg within week	NA	NA	NA	NA	10770637
OV_860	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	1 MOI	94% cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_861	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	1 MOI	75 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_862	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	80 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_863	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	1 MOI	99% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_864	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	1 MOI	92% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_865	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	96% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_866	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	0.1 MOI	60% cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_867	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	0.1 MOI	40 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_868	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	60 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_869	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	0.1 MOI	95% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_870	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	0.1 MOI	80% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_871	Herpes simplex virus	BL1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	80% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_872	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	1 MOI	94% cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_873	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	1 MOI	85 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_874	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	85 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_875	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	1 MOI	98% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_876	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	1 MOI	96% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_877	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	1 MOI	97% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_878	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	0.1 MOI	60% cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_879	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	0.1 MOI	60 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_880	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	60 % cancerous cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_881	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Cellosaurus cell line	SK-MEL-28	NA	NA	MTT assay	0.1 MOI	95% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_882	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Triple-negative breast cancer cell line	MDA-MB-231	NA	NA	MTT assay	0.1 MOI	88% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_883	Herpes simplex virus	JS1	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human colorectal adenocarcinoma cell line	HT-29	NA	NA	MTT assay	0.1 MOI	88% cancerous cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12595888
OV_884	Herpes simplex virus	JS1	DNA	Herpesviridae	JS1 strain mutant in ICP34.5 and ICP47	Yes	No	No	ATCC	NA	NA	NA	NA	MTT assay	NA	NA	BALB/c nude mice xenograft for HT-29 cell	1.0E+8 pfu	NA	Compelte reduction of tumor after 28 days	intraperitonial	NA	Increase production of IFN-gamma	NA	12595888
OV_885	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	75% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_886	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	85% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_887	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	85% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_888	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	95% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_889	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	90% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_890	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.1 pfu/ml	95% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_891	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	70% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_892	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	75% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_893	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	80% cncer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_894	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	99% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_895	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Glioblastoma cell line	U-87 MG	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	80% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_896	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	Human prostate cancer cell line	Du145	3.0E+4 cells per well	NA	Trypan blue staining and hematocytometer	0.01 pfu/ml	80% cncer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	12788648
OV_897	Herpes simplex virus	Mutant	DNA	Herpesviridae	Deletion mutant for Gamma 34.5	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for Hep 3B cancer cell line	1.0E+7 pfu	NA	Complete reduction in tumor nodes after 4 weeks	intraperitonial	NA	NA	NA	12788648
OV_898	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	2% cancer cell killing after 24 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_899	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	20% cancer cell killing after 24 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_900	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	50% cancer cell killing after 24 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_901	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	20% cancer cell killing after 48 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_902	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	40% cancer cell killing after 48 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_903	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	80% cancer cell killing after 48 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_904	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	60% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_905	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	80% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_906	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.01 pfu/cell	90% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_907	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	20% cancer cell killing after 24 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_908	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	30% cancer cell killing after 24 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_909	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	50% cancer cell killing after 24 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_910	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	50% cancer cell killing after 48 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_911	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	60% cancer cell killing after 48 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_912	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	100% cancer cell killing after 48 hour	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_913	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	60% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_914	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	80% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_915	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	Prostate cancer cell line	PC-3M-Pro4	5.0E+4 cells per well	NA	Trypan blue staining	0.1 pfu/cell	100% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	15129429
OV_916	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line	2.0E+7 pfu	NA	30% reduction in tumor volume	Tail vein injection of virus	NA	NA	NA	15129429
OV_917	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line	2.0E+7 pfu	NA	50% reduction in tumor volume	Tail vein injection of virus	NA	NA	NA	15129429
OV_918	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/cByJIcrSmnHsd-scid mice orthotopic xenograft for prostate cancer cell line	2.0E+7 pfu	NA	60% reduction in tumor volume	Tail vein injection of virus	NA	NA	NA	15129429
OV_919	Herpes simplex virus	Baco-1	DNA	Herpesviridae	Non- fusogenic ligated with EGFP protein	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model	2.0E+7 pfu	NA	Lung metastasis were not detected after 40 days when stained with bouins fixative	Tail vein injection of virus	NA	NA	NA	15129429
OV_920	Herpes simplex virus	Synco-2	DNA	Herpesviridae	Fusogenic membrane ligated with GALV.fus protein	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model	2.0E+7 pfu	NA	Lung metastasis were not detected after 40 days when stained with bouins fixative	Tail vein injection of virus	NA	NA	NA	15129429
OV_921	Herpes simplex virus	Synco-2D	DNA	Herpesviridae	Double fusogenic expressing EGFP and GALV.fus protein	Yes	No	No	ATCC	NA	NA	NA	NA	NA	NA	NA	BALB/cByJIcrSmnHsd-scid mice metastatic lung metastatic model	2.0E+7 pfu	NA	Lung metastasis were not detected after 40 days when stained with bouins fixative	Tail vein injection of virus	NA	NA	NA	15129429
OV_991	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10 pfu/cell	90% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_992	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	100 pfu/cell	90% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_993	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	1000 pfu/cell	80% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_994	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10000 pfu/cell	60% cell kills after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_995	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10 pfu/cell	90% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_996	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	100 pfu/cell	50% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_997	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	1000 pfu/cell	20% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_998	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell kills after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_999	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10 pfu/cell	60% cell survival after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1000	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell kills after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1001	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell kills after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1002	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell kills after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1003	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10 pfu/cell	10% cell kills after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1004	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell kills after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1005	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell kills after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1006	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SK-N-SH	4.0E+3 cells per well	NA	NA	10000 pfu/cell	100% cell kills after 8 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1007	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1008	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1009	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	1000 pfu/cell	100% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1010	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10000 pfu/cell	90% cell survival after 2 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1011	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1012	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	100 pfu/cell	100% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1013	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	1000 pfu/cell	90% cell survival after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1014	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10000 pfu/cell	50% cell kills after 4 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577
OV_1015	Herpes simplex virus	HSV-1	DNA	Herpesviridae	Mutant NV1066	Yes	No	No	MediGene Inc. San Diego, CA	Neuroblastoma cell line	SHSY5Y	4.0E+3 cells per well	NA	NA	10 pfu/cell	100% cell survivalk after 6 days	No	No	NA	No response	NA	Apoptosis induction and cspase 3 activation	NA	NA	15570577