Detailed description page of Selected OV_ID


OV_846 details
Primary information
OV_IDOV_846
Virus Name Herpes simplex virus
StrainHSV-G207
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant in ICP34.5 and ICPC6 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineEpithelial ovarian carcinoma
Cell lineA2781
Concentration of cell line3
In-vitro toxicityMinimal cytotoxic to mesothelial cells
AssayBeta galacosidase colorimetric proliferation assay
In-vitro virus concentration0.1 MOI
In-vitro result75% cancer cell killing
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID10770637