Detailed description page of Selected OV_ID


OV_854 details
Primary information
OV_IDOV_854
Virus Name Herpes simplex virus
StrainHSV-G207
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant in ICP34.5 and ICPC6 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismFemale CB17 SCID mice model xenograft for SKOV3 cell
In-vivo virus concentration5 × 10⁶ pfu
In-vivo toxicityNA
In-vivo resultReduction in tumor growth to 50mg compared to control of 300mg within week
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID10770637