| Primary information |
|---|
| OV_ID | OV_854 |
| Virus Name | Herpes simplex virus |
| Strain | HSV-G207 |
| Virus type | DNA |
| Virus family | Herpesviridae |
| Modification in virus genome | Deletion mutant in ICP34.5 and ICPC6 gene |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | Female CB17 SCID mice model xenograft for SKOV3 cell |
| In-vivo virus concentration | 5 × 10ⶠpfu |
| In-vivo toxicity | NA |
| In-vivo result | Reduction in tumor growth to 50mg compared to control of 300mg within week |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 10770637 |