| Primary information |
|---|
| OV_ID | OV_895 |
| Virus Name | Herpes simplex virus |
| Strain | Mutant |
| Virus type | DNA |
| Virus family | Herpesviridae |
| Modification in virus genome | Deletion mutant for Gamma 34.5 |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | ATCC |
| Origin of cell line | Glioblastoma cell line |
| Cell line | U-87 MG |
| Concentration of cell line | 3 |
| In-vitro toxicity | NA |
| Assay | Trypan blue staining and hematocytometer |
| In-vitro virus concentration | 0.01 pfu/ml |
| In-vitro result | 80% cncer cell killing after 48 hours |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 12788648 |