Detailed description page of Selected OV_ID


OV_889 details
Primary information
OV_IDOV_889
Virus Name Herpes simplex virus
StrainMutant
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant for Gamma 34.5
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineGlioblastoma cell line
Cell lineU-87 MG
Concentration of cell line3
In-vitro toxicityNA
AssayTrypan blue staining and hematocytometer
In-vitro virus concentration0.1 pfu/ml
In-vitro result90% cncer cell killing after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID12788648