A database of hormones and their receptors |
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HMRbase accession number | 20002 |
Swiss-prot Accession number | O15970 (Sequence in FASTA format) |
Description | Serotonin receptor-like planarian receptor 1. |
Source organism | Dugesia japonica (Planarian) |
Taxonomical Classification | Eukaryota; Metazoa; Platyhelminthes; Turbellaria; Seriata; Tricladida;Paludicola; Dugesiidae; Dugesia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 525 Amino acids |
Molecular weight | 59178 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9300820 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20003 |
Swiss-prot Accession number | Q9GQ54 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 7 receptor. |
Source organism | Aedes aegypti (Yellowfever mosquito) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;Culicinae; Culicini; Aedes; Stegomyia. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 464 Amino acids |
Molecular weight | 50822 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11520359 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20005 |
Swiss-prot Accession number | Q95KV8 (Sequence in FASTA format) |
Description | Melanocortin 1-receptor. |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 321 Amino acids |
Molecular weight | 35313 |
Domain Name | 7tm_1 |
References | 1 Kriegesmann B., Dierkes B., Leeb T., Jansen S., Brenig B.; "Two breed specific bovine MC1-R alleles in Brown Swiss and Salerbreeds."; Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20006 |
Swiss-prot Accession number | Q7TT86 (Sequence in FASTA format) |
Description | Somatostatin receptor. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 390 Amino acids |
Molecular weight | 42589 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1400442 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20007 |
Swiss-prot Accession number | Q869J1 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Ciona intestinalis (Transparent sea squirt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Urochordata; Ascidiacea; Enterogona;Phlebobranchia; Cionidae; Ciona. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 401 Amino acids |
Molecular weight | 45358 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14644499 |
Hormone | N/A |
Gene ID | 445658 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20008 |
Swiss-prot Accession number | Q9TTM9 (Sequence in FASTA format) |
Description | Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. |
Protein Length | 571 Amino acids |
Molecular weight | 60699 |
Domain Name | 7tm_1 |
References | 1 Uhlen S., Wraith A.; "Characterization of the pig alpha-1D adrenergic receptor."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 552898 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20009 |
Swiss-prot Accession number | Q800V8 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 1. |
Source organism | Rana dybowskii (Dybovsky's frog) (Korean brown frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Rana. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 407 Amino acids |
Molecular weight | 45993 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12538604 |
Hormone | Q9IAU2 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20012 |
Swiss-prot Accession number | P56449 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 391 Amino acids |
Molecular weight | 43378 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8534370 2 PubMed abstract 8534370 |
Hormone | P01175 Detail in HMRbase |
Gene ID | 281371 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20013 |
Swiss-prot Accession number | P79266 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 454 Amino acids |
Molecular weight | 48781 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8851180 2 Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 8851180 4 Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01352 Detail in HMRbase P41520 Detail in HMRbase |
Gene ID | 281665 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20019 |
Swiss-prot Accession number | Q9TU77 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 295 Amino acids |
Molecular weight | 33019 |
Domain Name | 7tm_1 |
References | 1 Wang J., Rose J.C.; "Ovine adrenal ACTH receptor: cDNA cloning and developmental changesof mRNA levels."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
2 Wang J., Rose J.C.; "Ovine adrenal ACTH receptor: cDNA cloning and developmental changesof mRNA levels."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01191 Detail in HMRbase |
Gene ID | 443482 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20047 |
Swiss-prot Accession number | Q92847 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary and hypothalamus. |
Post translational modification | N/A |
Function | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). |
Protein Length | 366 Amino acids |
Molecular weight | 41329 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8688086 2 PubMed abstract 11356716 3 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15489334 5 PubMed abstract 11322507 6 PubMed abstract 10604470 |
Hormone | N/A |
Gene ID | 2693 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20048 |
Swiss-prot Accession number | Q95254 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary and hypothalamus. |
Post translational modification | N/A |
Function | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). |
Protein Length | 366 Amino acids |
Molecular weight | 41195 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8688086 |
Hormone | N/A |
Gene ID | 397372 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20049 |
Swiss-prot Accession number | Q19PY9 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Bos mutus grunniens (Wild yak) (Bos grunniens) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 328 Amino acids |
Molecular weight | 37756 |
Domain Name | 7tm_1 |
References | 1 Yu J.C.; "Molecular clone and sequence analysis of GnRHR, CGA, FSHB and LHBgenes related to spermatogenesis of the Yak."; Thesis (2006), Southwest University for Nationalities, China.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20050 |
Swiss-prot Accession number | P32236 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 328 Amino acids |
Molecular weight | 37741 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8306635 2 Nelson S.E., Quirk C.E., Clay C.M.; "Bovine gonadotropin releasing hormone receptor gene."; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 281798 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20051 |
Swiss-prot Accession number | Q9MZI6 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 327 Amino acids |
Molecular weight | 37656 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10809231 |
Hormone | N/A |
Gene ID | 403718 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20052 |
Swiss-prot Accession number | O18821 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 328 Amino acids |
Molecular weight | 37649 |
Domain Name | 7tm_1 |
References | 1 Porter M.B., Green M.L., Simmen R.C.M., Sharp D.C.; "Cloning and sequencing of the equine pituitary gonadotropin-releasinghormone receptor and expression of its mRNA following administrationof pulsatile or continuous GnRH."; Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | 100033874 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20053 |
Swiss-prot Accession number | Q9TTI8 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Trichosurus vulpecula (Brush-tailed possum) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Diprotodontia; Phalangeridae; Trichosurus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 328 Amino acids |
Molecular weight | 37986 |
Domain Name | 7tm_1 |
References | 1 Lawrence S.B., McNatty K.P., Fidler A.E.; Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20054 |
Swiss-prot Accession number | Q95MG6 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
Source organism | Callithrix jacchus (Common marmoset) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Callithrix. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 380 Amino acids |
Molecular weight | 41991 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11493674 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20055 |
Swiss-prot Accession number | Q95MH6 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
Source organism | Cercopithecus aethiops (Green monkey) (Grivet) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 379 Amino acids |
Molecular weight | 41435 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11352653 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20064 |
Swiss-prot Accession number | Q90674 (Sequence in FASTA format) |
Description | Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (LSH-R)(Luteinizing hormone receptor) (Fragment). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 366 Amino acids |
Molecular weight | 40760 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8828833 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20066 |
Swiss-prot Accession number | Q8MJ89 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Fragment). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis (By similarity). |
Protein Length | 388 Amino acids |
Molecular weight | 42777 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12036292 2 PubMed abstract 12182940 |
Hormone | N/A |
Gene ID | 574232 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20067 |
Swiss-prot Accession number | Q5IJ49 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis (By similarity). |
Protein Length | 422 Amino acids |
Molecular weight | 45963 |
Domain Name | 7tm_1 |
References | 1 Reichwald K., Petz U., Huse K., Enard W., Platzer M.; "Cloning of Pan troglodytes G-protein coupled receptor 24 (GPR24)mRNA."; Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 470220 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20068 |
Swiss-prot Accession number | Q8SQ54 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2)(MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145)(GPRv17). |
Source organism | Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. |
Protein Length | 340 Amino acids |
Molecular weight | 38770 |
Domain Name | 7tm_1 |
References | 1 Kurama T., Matsumoto S., Takasaki J., Terai K., Matsumoto M.,Kamohara M., Saito T., Soga T., Saito Y., Oda T., Masuho Y.,Furuichi K.; "Molecular characterization of a novel melanin-concentrating hormonereceptor: evidence of its expression in lateral hypothalamus."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20069 |
Swiss-prot Accession number | Q8MJ88 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2)(MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Specifically expressed in the brain with highest levels in cerebral cortex, hippocampus and hypothalamus, and lower levels in caudate nucleus, putamen and thalamus. |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. |
Protein Length | 340 Amino acids |
Molecular weight | 38784 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12182940 2 PubMed abstract 12036292 |
Hormone | N/A |
Gene ID | 574369 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20218 |
Swiss-prot Accession number | O46639 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 398 Amino acids |
Molecular weight | 45165 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9492373 |
Hormone | N/A |
Gene ID | 281549 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20220 |
Swiss-prot Accession number | Q25397 (Sequence in FASTA format) |
Description | Conopressin receptor 2. |
Source organism | Lymnaea stagnalis (Great pond snail) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Pulmonata; Basommatophora;Lymnaeoidea; Lymnaeidae; Lymnaea. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 520 Amino acids |
Molecular weight | 59436 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8631971 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20221 |
Swiss-prot Accession number | P47898 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5-HT-5). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. |
Protein Length | 357 Amino acids |
Molecular weight | 40255 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7988681 2 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 15489334 4 PubMed abstract 7988681 5 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 |
Hormone | Detail in HMRbase |
Gene ID | 3361 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20222 |
Swiss-prot Accession number | Q6VB83 (Sequence in FASTA format) |
Description | Serotonin receptor. |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 365 Amino acids |
Molecular weight | 41653 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14744596 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20223 |
Swiss-prot Accession number | Q6VWJ2 (Sequence in FASTA format) |
Description | Serotonin receptor. |
Source organism | Boophilus microplus (Cattle tick) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Chelicerata; Arachnida; Acari;Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Rhipicephalinae;Rhipicephalus; Boophilus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 374 Amino acids |
Molecular weight | 42157 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14728666 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20224 |
Swiss-prot Accession number | Q9GKI2 (Sequence in FASTA format) |
Description | 5-HT1F receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 366 Amino acids |
Molecular weight | 41970 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11834243 |
Hormone | N/A |
Gene ID | 397187 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20225 |
Swiss-prot Accession number | Q6QZW5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor (Melanocortin receptor 1). |
Source organism | Sus scrofa coreanus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34592 |
Domain Name | 7tm_1 |
References | 1 Cho I.C., Jung J.K., Jung Y.H., Jeon J.T.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
2 Cho I.C., Hwang J.H., Jeon J.T., Andersson L., Han S.H.; "Genetic Variation of MC1R gene in Korean wild boar."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20228 |
Swiss-prot Accession number | O42574 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor) (X-BETA1AR). |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins (By similarity). |
Protein Length | 385 Amino acids |
Molecular weight | 43309 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9395292 |
Hormone | N/A |
Gene ID | 399337 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20229 |
Swiss-prot Accession number | Q38PT0 (Sequence in FASTA format) |
Description | Alpha 2b adrenergic receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 446 Amino acids |
Molecular weight | 49582 |
Domain Name | 7tm_1 |
References | 1 Mehrotra S., Teunissen A.W.R.H., Saxena P.R., Sharma H.S.; "Molecular Cloning and Tissue Distribution of a Full Length cDNAEncoding Porcine Alpha 2b Adrenergic Receptor."; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 641353 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20230 |
Swiss-prot Accession number | Q5VXR2 (Sequence in FASTA format) |
Description | Adrenergic, alpha-1D-, receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium (By similarity). |
Protein Length | 572 Amino acids |
Molecular weight | 60463 |
Domain Name | 7tm_1 |
References | 1 Beasley H.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20231 |
Swiss-prot Accession number | Q925K7 (Sequence in FASTA format) |
Description | Adrenergic receptor alpha 2B. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 448 Amino acids |
Molecular weight | 50018 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11471062 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20233 |
Swiss-prot Accession number | Q3V5M1 (Sequence in FASTA format) |
Description | Thyroid stimulating hormone receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 761 Amino acids |
Molecular weight | 86710 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16709612 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20234 |
Swiss-prot Accession number | Q4L191 (Sequence in FASTA format) |
Description | Luteinizing hormone receptor precursor. |
Source organism | Dicentrarchus labrax (European sea bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Dicentrarchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 721 Amino acids |
Molecular weight | 80198 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 17420017 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20237 |
Swiss-prot Accession number | Q6K0L4 (Sequence in FASTA format) |
Description | Follicle-stimulating hormone receptor. |
Source organism | Bothrops jararaca (Jararaca) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea;Viperidae; Crotalinae; Bothrops. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 673 Amino acids |
Molecular weight | 76608 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15201068 2 Bluhm A.P.C., Mesquita F.M., Lazari M.F.M.; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20243 |
Swiss-prot Accession number | Q71MM9 (Sequence in FASTA format) |
Description | Luteinizing hormone receptor LHR. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 727 Amino acids |
Molecular weight | 80628 |
Domain Name | 7tm_1 |
References | 1 Sambroni E., Breton B.; "Oncorhynchus mykiss rtLHR mRNA for luteinizing hormone receptor."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100135989 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20250 |
Swiss-prot Accession number | Q90WP8 (Sequence in FASTA format) |
Description | FSH receptor. |
Source organism | Podarcis sicula (Italian wall lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Lacertoidea;Lacertidae; Podarcis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 673 Amino acids |
Molecular weight | 76288 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11574163 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20251 |
Swiss-prot Accession number | Q98TF4 (Sequence in FASTA format) |
Description | Thyrotropin receptor. |
Source organism | Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 778 Amino acids |
Molecular weight | 87126 |
Domain Name | 7tm_1 |
References | 1 Oba Y., Nagahama Y.; "tilapia thyrotropin receptor."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20259 |
Swiss-prot Accession number | Q9PVP0 (Sequence in FASTA format) |
Description | Gonadotropin receptor II. |
Source organism | Oncorhynchus rhodurus (amago) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 724 Amino acids |
Molecular weight | 80495 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10491336 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20262 |
Swiss-prot Accession number | O43192 (Sequence in FASTA format) |
Description | Vasopressin receptor type 2. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 309 Amino acids |
Molecular weight | 33743 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1534149 2 PubMed abstract 8735975 3 PubMed abstract 1415251 4 Du J., Fay M.J., Yu X., North W.G.; "A truncated human vasopressin receptor type 2 produced by alternativesplicing intron 2 in small-cellcarcinoma of the lung."; Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20264 |
Swiss-prot Accession number | Q3SWS1 (Sequence in FASTA format) |
Description | Arginine vasopressin receptor 2. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 40645 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. 3 Johnson C.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 12000 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20265 |
Swiss-prot Accession number | Q3SWS4 (Sequence in FASTA format) |
Description | Avpr2 protein (Arginine vasopressin receptor 2). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 334 Amino acids |
Molecular weight | 36203 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. 3 Johnson C.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20269 |
Swiss-prot Accession number | Q5MZ03 (Sequence in FASTA format) |
Description | Vasotocin receptor V1-alpha. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 447 Amino acids |
Molecular weight | 50036 |
Domain Name | 7tm_1 |
References | 1 Yamaguchi F., Yamaguchi K., Brenner S.; "Molecular cloning of Fugu vasotocin receptor genes."; Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20271 |
Swiss-prot Accession number | Q8AYS6 (Sequence in FASTA format) |
Description | V2 type arginine vasotocin receptor. |
Source organism | Hyla japonica (Japanese tree frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Hylinae;Hylini; Hyla. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 363 Amino acids |
Molecular weight | 41123 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12849972 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20274 |
Swiss-prot Accession number | Q9JLP2 (Sequence in FASTA format) |
Description | Arginine vasopressin type 1b receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 421 Amino acids |
Molecular weight | 46516 |
Domain Name | 7tm_1 |
References | 1 O'Carroll A.-M., Selby T., Young W.S. III, Lolait S.J.; "Cloning, sequence and tissue distribution of the gene encoding amouse arginine vasopressin type 1b receptor."; Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20277 |
Swiss-prot Accession number | Q9QW17 (Sequence in FASTA format) |
Description | V2 arginine vasopressin receptor. |
Source organism | Rattus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus; unclassified Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 370 Amino acids |
Molecular weight | 40518 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8511367 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20278 |
Swiss-prot Accession number | Q90334 (Sequence in FASTA format) |
Description | Isotocin receptor (ITR). |
Source organism | Catostomus commersoni (White sucker) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Catostomidae; Catostomus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in brain, intestine, bladder, skeletal muscle, lateral line, gills and kidney. |
Post translational modification | N/A |
Function | Binds to isotocin. Can also be activated by vasotocin, mesotocin, oxytocin and Arg-vasopressin, although these have lower potencies than isotocin. Produces an induction of membrane chloride currents indicating that it is coupled to the inositol phosphate/calcium pathway. |
Protein Length | 390 Amino acids |
Molecular weight | 44504 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7656982 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20279 |
Swiss-prot Accession number | Q90252 (Sequence in FASTA format) |
Description | Mesotocin receptor (MTR). |
Source organism | Bufo marinus (Giant toad) (Cane toad) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Bufo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Highly expressed in the bladder. Also expressed in kidney, brain and skeletal muscle. |
Post translational modification | N/A |
Function | Binds to mesotocin and may play a role in the regulation of water and salt transport. |
Protein Length | 389 Amino acids |
Molecular weight | 44384 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8647123 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20280 |
Swiss-prot Accession number | Q3LRX3 (Sequence in FASTA format) |
Description | Mesotocin receptor. |
Source organism | Taricha granulosa (Roughskin newt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Caudata; Salamandroidea; Salamandridae; Taricha. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 393 Amino acids |
Molecular weight | 45049 |
Domain Name | 7tm_1 |
References | 1 Searcy B.T., Filtz T.M., Moore F.L.; "Identification and Characterization of the Mesotocin Receptor fromthe Brain of the Rough-skinned Newt, Taricha granulosa."; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20281 |
Swiss-prot Accession number | Q5D7U5 (Sequence in FASTA format) |
Description | Oxytocin-like receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 391 Amino acids |
Molecular weight | 44043 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16005652 |
Hormone | N/A |
Gene ID | 429211 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20283 |
Swiss-prot Accession number | Q8AYS5 (Sequence in FASTA format) |
Description | Mesotocin receptor. |
Source organism | Hyla japonica (Japanese tree frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae; Hylinae;Hylini; Hyla. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 389 Amino acids |
Molecular weight | 44534 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12849972 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20284 |
Swiss-prot Accession number | Q8R561 (Sequence in FASTA format) |
Description | Oxytocin receptor. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 388 Amino acids |
Molecular weight | 42954 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9004255 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20285 |
Swiss-prot Accession number | Q9BDP3 (Sequence in FASTA format) |
Description | Endometrial oxytocin receptor. |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 391 Amino acids |
Molecular weight | 43154 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11006161 2 Feng H.C., Bhave M., Fairclough R.J.; Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 443138 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20286 |
Swiss-prot Accession number | Q75W84 (Sequence in FASTA format) |
Description | Annetocin receptor. |
Source organism | Eisenia foetida (Common brandling worm) (Common dung-worm) |
Taxonomical Classification | Eukaryota; Metazoa; Annelida; Clitellata; Oligochaeta; Haplotaxida;Lumbricina; Lumbricidae; Eisenia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Nephridia in clitellum region. |
Post translational modification | N/A |
Function | Receptor for annetocin. Activation by annetocin may induce egg-laying behavior through calcium-dependent signaling. |
Protein Length | 420 Amino acids |
Molecular weight | 46410 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15175002 2 PubMed abstract 15175002 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20287 |
Swiss-prot Accession number | Q25396 (Sequence in FASTA format) |
Description | Conopressin receptor. |
Source organism | Lymnaea stagnalis (Great pond snail) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Pulmonata; Basommatophora;Lymnaeoidea; Lymnaeidae; Lymnaea. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 462 Amino acids |
Molecular weight | 52279 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7576638 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20288 |
Swiss-prot Accession number | Q7YW31 (Sequence in FASTA format) |
Description | Cephalotocin receptor 1 (OT/VP superfamily peptide receptor 1) (OC/CE-R 1). |
Source organism | Octopus vulgaris (Octopus) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Cephalopoda; Coleoidea; Neocoleoidea;Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus. |
Subcellular location | Cell membrane; multi-pass membrane protein (Potential) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Present in brain, buccal ganglion, gastric ganglion, olfactory lube, peduncle lobe, optical lobe, pancreas, the oviduct and the ovary. |
Post translational modification | N/A |
Function | Acts as a receptor for cephalotocin. |
Protein Length | 397 Amino acids |
Molecular weight | 45751 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14596680 2 PubMed abstract 15504101 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20289 |
Swiss-prot Accession number | Q6XXX9 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 423 Amino acids |
Molecular weight | 46356 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15220384 |
Hormone | N/A |
Gene ID | 487230 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20291 |
Swiss-prot Accession number | P08908 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A) (G-21). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 422 Amino acids |
Molecular weight | 46107 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 3041227 2 Saltzman A.G., Morse B., Felder S.; Submitted (FEB-1991) to the EMBL/GenBank/DDBJ databases. 3 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 4 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15489334 6 PubMed abstract 1766875 7 PubMed abstract 8393041 8 PubMed abstract 3138543 9 PubMed abstract 17203973 10 PubMed abstract 7755630 11 PubMed abstract 9754630 |
Hormone | N/A |
Gene ID | 3350 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20292 |
Swiss-prot Accession number | Q64264 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Most abundantly expressed in midbrain and cortex. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 421 Amino acids |
Molecular weight | 46124 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8254366 2 PubMed abstract 8626793 3 PubMed abstract 8288218 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20295 |
Swiss-prot Accession number | P19327 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 422 Amino acids |
Molecular weight | 46429 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2156831 2 PubMed abstract 2167416 |
Hormone | N/A |
Gene ID | 24473 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20296 |
Swiss-prot Accession number | Q6XXY0 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A). |
Source organism | Vulpes vulpes (Red fox) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Vulpes. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 423 Amino acids |
Molecular weight | 46284 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15220384 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20297 |
Swiss-prot Accession number | P79250 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HTR1B) (5-HT1D subtype beta). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 389 Amino acids |
Molecular weight | 42930 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14729271 2 PubMed abstract 15353848 3 PubMed abstract 15220384 4 PubMed abstract 8763409 |
Hormone | N/A |
Gene ID | 403741 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20298 |
Swiss-prot Accession number | O08892 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 389 Amino acids |
Molecular weight | 43111 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9225276 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20299 |
Swiss-prot Accession number | P46636 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Cricetulus griseus (Chinese hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Cricetulus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 386 Amino acids |
Molecular weight | 42896 |
Domain Name | 7tm_1 |
References | 1 Wurch T., Palmier C., Colpaert F.C., Pauwels P.J.; "Molecular cloning and expression of a Chinese hamster lung fibroblastcDNA encoding a 5-HT1B receptor."; Submitted (APR-1995) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20300 |
Swiss-prot Accession number | P35404 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Didelphis marsupialis virginiana (North American opossum) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Didelphimorphia; Didelphidae; Didelphis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 388 Amino acids |
Molecular weight | 43111 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8302276 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20301 |
Swiss-prot Accession number | Q588Y6 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 389 Amino acids |
Molecular weight | 43372 |
Domain Name | 7tm_1 |
References | 1 Asahi D., Mori Y.; "Felis catus 5-hydroxytryptamine (serotonin) receptor 1B (Htr1b),mRNA."; Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100144391 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20303 |
Swiss-prot Accession number | P28222 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation. Palmitoylated. |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 390 Amino acids |
Molecular weight | 43568 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1565658 2 PubMed abstract 1351684 3 PubMed abstract 1610347 4 PubMed abstract 1315531 5 PubMed abstract 1559993 6 PubMed abstract 1328844 7 PubMed abstract 1348246 8 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 9 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 10 PubMed abstract 14574404 11 PubMed abstract 15489334 12 PubMed abstract 8218242 13 PubMed abstract 7802650 14 PubMed abstract 1565658 15 PubMed abstract 1351684 16 PubMed abstract 1610347 17 PubMed abstract 1315531 18 PubMed abstract 1559993 19 PubMed abstract 1328844 20 PubMed abstract 1348246 21 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 22 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 23 PubMed abstract 14574404 24 PubMed abstract 15489334 25 PubMed abstract 8218242 26 PubMed abstract 7802650 |
Hormone | N/A |
Gene ID | 3351 |
PDB ID | 2G1X |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20304 |
Swiss-prot Accession number | P28334 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Predominantly expressed in striatum and Purkinje cells. |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 386 Amino acids |
Molecular weight | 43079 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1557407 |
Hormone | N/A |
Gene ID | 15551 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20305 |
Swiss-prot Accession number | P60020 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 390 Amino acids |
Molecular weight | 43568 |
Domain Name | 7tm_1 |
References | 1 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 462833 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20306 |
Swiss-prot Accession number | P49144 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HT-1D-beta). |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 390 Amino acids |
Molecular weight | 43496 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8543023 2 Wurch T., Cathala C., Palmer C., Valentin J.P., John G.,Colpaert F.C., Pauwels P.J.; "Molecular cloning and identification of a rabbit saphenous vein 5-HT1DB receptor gene."; Neurosci. Res. Commun. 18:155-162(1996). 3 PubMed abstract 8878052 |
Hormone | N/A |
Gene ID | 100009594 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20307 |
Swiss-prot Accession number | P28564 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 386 Amino acids |
Molecular weight | 43163 |
Domain Name | 7tm_1 |
References | 1 Hamblin M.W., McGuffin R.W., Metcalf M.A., Dorsa D.M., Merchant K.M.; "Distinct 5-HT1B and 5-HT1D serotonin receptors in rat: structural andpharmacological comparison of the two cloned receptors."; Mol. Cell. Neurosci. 3:578-587(1992).
2 PubMed abstract 1836757 |
Hormone | N/A |
Gene ID | 25075 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20308 |
Swiss-prot Accession number | P56496 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B). |
Source organism | Spalax leucodon ehrenbergi (Ehrenberg's mole rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Spalacidae; Spalacinae; Nannospalax. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 386 Amino acids |
Molecular weight | 43102 |
Domain Name | 7tm_1 |
References | 1 Devor E.J., Nevo E.; Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20309 |
Swiss-prot Accession number | Q6XXX8 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5-HT1B) (5-HTR1B). |
Source organism | Vulpes vulpes (Red fox) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Vulpes. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated (By similarity). Palmitoylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 389 Amino acids |
Molecular weight | 42990 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15220384 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20310 |
Swiss-prot Accession number | P11614 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 377 Amino acids |
Molecular weight | 41883 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2541503 2 PubMed abstract 2159630 3 PubMed abstract 1659418 4 PubMed abstract 1758439 |
Hormone | N/A |
Gene ID | 403963 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20311 |
Swiss-prot Accession number | Q60484 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 376 Amino acids |
Molecular weight | 41769 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8978753 2 PubMed abstract 9225276 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20312 |
Swiss-prot Accession number | P79748 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D)(5HT1D) (F1D). |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 379 Amino acids |
Molecular weight | 42302 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9218723 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20313 |
Swiss-prot Accession number | P28221 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D) (5-HT-1D-alpha). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 377 Amino acids |
Molecular weight | 41907 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1652050 2 PubMed abstract 1565658 3 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 4 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 16710414 6 PubMed abstract 15489334 7 PubMed abstract 10391209 8 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). |
Hormone | N/A |
Gene ID | 3352 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20314 |
Swiss-prot Accession number | Q61224 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 374 Amino acids |
Molecular weight | 41540 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8978753 2 PubMed abstract 8288218 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20315 |
Swiss-prot Accession number | P49145 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D) (5-HT-1D-alpha). |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 377 Amino acids |
Molecular weight | 41500 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8543023 2 PubMed abstract 8878052 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20316 |
Swiss-prot Accession number | P28565 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor (5-HT-1D) (Serotonin receptor 1D). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 374 Amino acids |
Molecular weight | 41540 |
Domain Name | 7tm_1 |
References | 1 Hamblin M.W., McGuffin R.W., Metcalf M.A., Dorsa D.M., Merchant K.M.; "Distinct 5-HT1B and 5-HT1D serotonin receptors in rat: structural andpharmacological comparison of the two cloned receptors."; Mol. Cell. Neurosci. 3:578-587(1992).
|
Hormone | N/A |
Gene ID | 25323 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20317 |
Swiss-prot Accession number | P28566 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1E receptor (5-HT-1E) (Serotonin receptor 1E) (5-HT1E) (S31). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 365 Amino acids |
Molecular weight | 41682 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1608964 2 PubMed abstract 1733778 3 PubMed abstract 1513320 4 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 14574404 6 PubMed abstract 15489334 7 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 10391209 9 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). |
Hormone | N/A |
Gene ID | 3354 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20318 |
Swiss-prot Accession number | O08890 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F) (5-HT1F). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 366 Amino acids |
Molecular weight | 41839 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9225282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20319 |
Swiss-prot Accession number | P30939 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 366 Amino acids |
Molecular weight | 41709 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8384716 2 PubMed abstract 8380639 3 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15489334 |
Hormone | N/A |
Gene ID | 3355 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20320 |
Swiss-prot Accession number | Q02284 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F) (5-HT-1E-beta). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 366 Amino acids |
Molecular weight | 41977 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1328180 |
Hormone | N/A |
Gene ID | 15557 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20321 |
Swiss-prot Accession number | P30940 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1F receptor (5-HT-1F) (Serotonin receptor 1F). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
Protein Length | 366 Amino acids |
Molecular weight | 41880 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8384716 |
Hormone | N/A |
Gene ID | 60448 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20322 |
Swiss-prot Accession number | P20905 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 1 (5-HT receptor) (Serotonin receptor 1)(5HT-dro). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed predominantly in adult heads. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 564 Amino acids |
Molecular weight | 60861 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2174167 2 PubMed abstract 10731132 3 PubMed abstract 12537572 4 Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.W.,Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,George R.A., Gonzalez M., Guarin H., Kronmiller B., Li P.W., Liao G.,Miranda A., Mungall C.J., Nunoo J., Pacleb J.M., Paragas V., Park S.,Patel S., Phouanenavong S., Wan K.H., Yu C., Lewis S.E., Rubin G.M.,Celniker S.E.; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 43669 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20323 |
Swiss-prot Accession number | Q75Z89 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
Protein Length | 470 Amino acids |
Molecular weight | 52571 |
Domain Name | 7tm_1 |
References | 1 Tahara K., Aso H., Yamasaki T., Yamaguchi T., Takano S.; "Expression of 5-HT2A during adipogenesis."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 407230 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20324 |
Swiss-prot Accession number | O46635 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2) (5-hydroxytryptamine receptor). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
Protein Length | 470 Amino acids |
Molecular weight | 52378 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15353848 2 PubMed abstract 15862800 3 Sgard F.; Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 403882 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20325 |
Swiss-prot Accession number | P18599 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Cricetulus griseus (Chinese hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Cricetulus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 471 Amino acids |
Molecular weight | 52702 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2402449 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20326 |
Swiss-prot Accession number | P28285 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 2A (5-HT receptor) (Serotonin receptor2A). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase. |
Protein Length | 834 Amino acids |
Molecular weight | 89521 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1310937 2 PubMed abstract 10731132 3 PubMed abstract 12537572 4 Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15611167 6 PubMed abstract 1310937 7 PubMed abstract 10731132 8 PubMed abstract 12537572 9 Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 10 PubMed abstract 15611167 |
Hormone | N/A |
Gene ID | 37196 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20327 |
Swiss-prot Accession number | P28223 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 471 Amino acids |
Molecular weight | 52603 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1722404 2 PubMed abstract 1323014 3 PubMed abstract 8035173 4 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15057823 6 PubMed abstract 15489334 7 Tritch R.J., Robinson D.L., Sahagan B.G., Horlick R.A.; "Cloning and nucleotide sequence of the human(5HT) type 2 receptor."; Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 1330647 9 PubMed abstract 11150294 10 PubMed abstract 14988405 11 PubMed abstract 8655141 12 PubMed abstract 10581480 13 PubMed abstract 10391209 14 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 15 PubMed abstract 1722404 16 PubMed abstract 1323014 17 PubMed abstract 8035173 18 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 19 PubMed abstract 15057823 20 PubMed abstract 15489334 21 Tritch R.J., Robinson D.L., Sahagan B.G., Horlick R.A.; "Cloning and nucleotide sequence of the human(5HT) type 2 receptor."; Submitted (MAY-1992) to the EMBL/GenBank/DDBJ databases. 22 PubMed abstract 1330647 23 PubMed abstract 11150294 24 PubMed abstract 14988405 25 PubMed abstract 8655141 26 PubMed abstract 10581480 27 PubMed abstract 10391209 28 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). |
Hormone | Detail in HMRbase |
Gene ID | 3356 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20328 |
Swiss-prot Accession number | P50128 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 471 Amino acids |
Molecular weight | 52603 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7794950 |
Hormone | N/A |
Gene ID | 613032 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20329 |
Swiss-prot Accession number | P35363 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein. Note=Localizes to the post-synaptic thickening of axo-dendritic synapses |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 471 Amino acids |
Molecular weight | 52842 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1333538 2 PubMed abstract 14988405 |
Hormone | N/A |
Gene ID | 15558 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20330 |
Swiss-prot Accession number | P50129 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2) (5-HT2A). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 470 Amino acids |
Molecular weight | 52676 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7794950 2 PubMed abstract 7656980 |
Hormone | N/A |
Gene ID | 397432 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20331 |
Swiss-prot Accession number | Q5R4Q6 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Pongo pygmaeus (Orangutan) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
Protein Length | 471 Amino acids |
Molecular weight | 52529 |
Domain Name | 7tm_1 |
References | 1 Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
2 Kitano T., Kobayakawa H., Saitou N.; "Silver project."; Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20332 |
Swiss-prot Accession number | P14842 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2A receptor (5-HT-2A) (Serotonin receptor 2A) (5-HT-2). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localizes to the post-synaptic thickening of axo-dendritic synapses (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production. |
Protein Length | 471 Amino acids |
Molecular weight | 52850 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2300586 2 PubMed abstract 2854054 3 PubMed abstract 1765383 |
Hormone | N/A |
Gene ID | 29595 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20333 |
Swiss-prot Accession number | P28286 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 2B (5-HT receptor) (Serotonin receptor2B). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase. |
Protein Length | 617 Amino acids |
Molecular weight | 67530 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1310937 2 PubMed abstract 10731132 3 PubMed abstract 12537572 |
Hormone | N/A |
Gene ID | 37191 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20334 |
Swiss-prot Accession number | P41595 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2B receptor (5-HT-2B) (Serotonin receptor 2B). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Detected in most peripheral organs. Only low expression levels were found in the brain. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 481 Amino acids |
Molecular weight | 54298 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8143856 2 PubMed abstract 7926008 3 PubMed abstract 8078486 4 PubMed abstract 10722792 5 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15815621 7 PubMed abstract 15489334 8 PubMed abstract 11150294 9 PubMed abstract 8143856 10 PubMed abstract 7926008 11 PubMed abstract 8078486 12 PubMed abstract 10722792 13 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 14 PubMed abstract 15815621 15 PubMed abstract 15489334 16 PubMed abstract 11150294 17 PubMed abstract 8143856 18 PubMed abstract 7926008 19 PubMed abstract 8078486 20 PubMed abstract 10722792 21 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 22 PubMed abstract 15815621 23 PubMed abstract 15489334 24 PubMed abstract 11150294 |
Hormone | N/A |
Gene ID | 3357 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20335 |
Swiss-prot Accession number | Q02152 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2B receptor (5-HT-2B) (Serotonin receptor 2B) (5-HT-2F) (NP75 protein). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Intestine and heart, but also in brain and kidney. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 479 Amino acids |
Molecular weight | 53625 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1426253 2 Choi D.S., Maroteaux L.; "Genomic sequence of the 5-HT2B receptor locus."; Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 11471062 4 PubMed abstract 16141072 5 PubMed abstract 15489334 |
Hormone | N/A |
Gene ID | 15559 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20336 |
Swiss-prot Accession number | P30994 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2B receptor (5-HT-2B) (Serotonin receptor 2B) (5-HT-2F) (Stomach fundus serotonin receptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Stomach fundus. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 479 Amino acids |
Molecular weight | 53652 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1505525 2 PubMed abstract 1331748 3 PubMed abstract 1505525 4 PubMed abstract 1331748 |
Hormone | N/A |
Gene ID | 29581 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20337 |
Swiss-prot Accession number | Q60F97 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 458 Amino acids |
Molecular weight | 51836 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15353848 |
Hormone | N/A |
Gene ID | 450240 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20338 |
Swiss-prot Accession number | P28335 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C) (5HT-1C). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated. |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 458 Amino acids |
Molecular weight | 51821 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1722404 2 PubMed abstract 7895773 3 PubMed abstract 8812491 4 PubMed abstract 9928237 5 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15772651 7 PubMed abstract 15489334 8 PubMed abstract 11150294 9 PubMed abstract 7557992 10 PubMed abstract 10206230 11 PubMed abstract 10581480 12 PubMed abstract 10391209 13 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). 14 PubMed abstract 1722404 15 PubMed abstract 7895773 16 PubMed abstract 8812491 17 PubMed abstract 9928237 18 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 19 PubMed abstract 15772651 20 PubMed abstract 15489334 21 PubMed abstract 11150294 22 PubMed abstract 7557992 23 PubMed abstract 10206230 24 PubMed abstract 10581480 25 PubMed abstract 10391209 26 Cargill M., Altshuler D., Ireland J., Sklar P., Ardlie K., Patil N.,Shaw N., Lane C.R., Lim E.P., Kalyanaraman N., Nemesh J., Ziaugra L.,Friedland L., Rolfe A., Warrington J., Lipshutz R., Daley G.Q.,Lander E.S.; Nat. Genet. 23:373-373(1999). |
Hormone | Detail in HMRbase |
Gene ID | 3358 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20339 |
Swiss-prot Accession number | P34968 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C) (5HT-1C). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 459 Amino acids |
Molecular weight | 51874 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1661811 2 PubMed abstract 1381232 3 PubMed abstract 1661811 4 PubMed abstract 1381232 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20340 |
Swiss-prot Accession number | Q5IS66 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 458 Amino acids |
Molecular weight | 51834 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15620360 |
Hormone | N/A |
Gene ID | 473740 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20341 |
Swiss-prot Accession number | P08909 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2C receptor (5-HT-2C) (Serotonin receptor 2C) (5-HT2C) (5-HTR2C) (5HT-1C). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N-glycosylated (By similarity). |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 460 Amino acids |
Molecular weight | 51917 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 3399891 2 PubMed abstract 12682077 |
Hormone | N/A |
Gene ID | 25187 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20342 |
Swiss-prot Accession number | O70528 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 388 Amino acids |
Molecular weight | 43726 |
Domain Name | 7tm_1 |
References | 1 Van den Wyngaert I., Gommeren W., Jurzak M., Verhasselt P., Gordon R.,Leysen J., Luyten W., Bender E.; "Cloning and expression of 5-HT4 receptor species and splicevariants."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20343 |
Swiss-prot Accession number | Q13639 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Isoform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 388 Amino acids |
Molecular weight | 43761 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9603189 2 Van den Wyngaert I., Gommeren W., Jurzak M., Verhasselt P., Gordon R.,Leysen J., Luyten W., Bender E.; "Cloning and expression of 5-HT4 receptor species and splicevariants."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 9351641 4 PubMed abstract 10220570 5 Vilaro M.T., Domenech T., Palacios J.M., Mengod G.; "Cloning and characterization of multiple human 5-HT4 receptorvariants including a novel variant that lacks the alternativelyspliced C-terminal exon."; Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 7 PubMed abstract 10646498 8 PubMed abstract 7656980 |
Hormone | Detail in HMRbase |
Gene ID | 3360 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20344 |
Swiss-prot Accession number | P97288 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 388 Amino acids |
Molecular weight | 43932 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8946946 2 Dumuis A.; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 9928238 4 PubMed abstract 10220570 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20345 |
Swiss-prot Accession number | Q62758 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | In brain, isoform 5-HT4S is restricted to the striatum, but isoform 5-HT4L is expressed throughout the brain, except in the cerebellum. In peripheral tissues, differential expression is also observed in the atrium of the heart where only isoform 5-HT4S is detectable. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 406 Amino acids |
Molecular weight | 46107 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7796807 2 PubMed abstract 7656980 3 PubMed abstract 10220570 |
Hormone | N/A |
Gene ID | 25324 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20346 |
Swiss-prot Accession number | P30966 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5-HT-5). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed predominantly in the central nervous system; in the cerebral cortex, hippocampus, habenula, olfactory bulb and granular layer of the cerebellum. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. |
Protein Length | 357 Amino acids |
Molecular weight | 40805 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1464308 2 PubMed abstract 8450829 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20347 |
Swiss-prot Accession number | P35364 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A)(REC17). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Central nervous system. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. |
Protein Length | 357 Amino acids |
Molecular weight | 40673 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7682702 |
Hormone | N/A |
Gene ID | 25689 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20348 |
Swiss-prot Accession number | P31387 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 5B receptor (5-HT-5B) (Serotonin receptor 5B). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed predominantly in the central nervous system; in the hippocampus, habenula, and the doral raphe. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Probably involved in anxiety and depression. |
Protein Length | 370 Amino acids |
Molecular weight | 41201 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8450829 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20349 |
Swiss-prot Accession number | P35365 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 5B receptor (5-HT-5B) (Serotonin receptor 5B)(MR22). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain; in the CA1 region of hippocampus, the medial habenula, and raphe nuclei. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins. Probably involved in anxiety and depression. |
Protein Length | 370 Amino acids |
Molecular weight | 41122 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7682702 2 PubMed abstract 8224165 |
Hormone | N/A |
Gene ID | 79247 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20350 |
Swiss-prot Accession number | P50406 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in several human brain regions, most prominently in the caudate nucleus. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. |
Protein Length | 440 Amino acids |
Molecular weight | 46954 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8522988 2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 15489334 4 PubMed abstract 7656980 5 PubMed abstract 16094384 |
Hormone | N/A |
Gene ID | 3362 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20351 |
Swiss-prot Accession number | Q9R1C8 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). |
Protein Length | 440 Amino acids |
Molecular weight | 46998 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11406289 |
Hormone | N/A |
Gene ID | 15565 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20352 |
Swiss-prot Accession number | Q5IS65 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs (By similarity). |
Protein Length | 440 Amino acids |
Molecular weight | 46952 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15620360 |
Hormone | N/A |
Gene ID | 469199 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20353 |
Swiss-prot Accession number | P31388 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 6 receptor (5-HT-6) (Serotonin receptor 6) (ST-B17). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Localized exclusively in the central nervous system, predominantly in the corpus striatum but also in various limbic and cortical regions. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs. |
Protein Length | 436 Amino acids |
Molecular weight | 46923 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7680751 2 PubMed abstract 8389146 3 Martial R.; "A novel rat serotonin (5HT6) receptor."; Submitted (JUN-1993) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 64354 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20354 |
Swiss-prot Accession number | P50407 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT-X). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 446 Amino acids |
Molecular weight | 49614 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7518496 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20355 |
Swiss-prot Accession number | P34969 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT-X) (5HT7). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels, and isoform D is a minor isoform. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 479 Amino acids |
Molecular weight | 53555 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9084407 2 PubMed abstract 8226867 3 King M.M., Aronstam R.S., Sharma S.V.; "Isolation of cDNA coding for 5-hydroxytryptamine receptor 7,transcript variant b (HTR7B)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15489334 5 PubMed abstract 9154233 |
Hormone | N/A |
Gene ID | 3363 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20356 |
Swiss-prot Accession number | P32304 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT-X) (5HT7). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 448 Amino acids |
Molecular weight | 49861 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8394987 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20357 |
Swiss-prot Accession number | P32305 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7) (5-HT-X) (5HT7) (GPRFO). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Thalamus, hypothalamus, and the hippocampal rudiments. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. This receptor is implicated in the regulation of mammalian circadian rhythms. |
Protein Length | 448 Amino acids |
Molecular weight | 49837 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8397408 2 PubMed abstract 8517926 3 PubMed abstract 8398139 4 PubMed abstract 8394362 5 PubMed abstract 9084407 |
Hormone | N/A |
Gene ID | 65032 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20358 |
Swiss-prot Accession number | Q91559 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 7 receptor (5-HT-7) (Serotonin receptor 7). |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 425 Amino acids |
Molecular weight | 48017 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8589994 |
Hormone | N/A |
Gene ID | 378527 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20359 |
Swiss-prot Accession number | Q16950 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1 receptor (5-HTB1) (Serotonin receptor 1). |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Reproductive system. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin). 5-HT plays important roles in various behavioral and physiological processes in aplysia. These include feeding, locomotion, circadian rhythm, learning and memory, synaptic plasticity, and synaptic growth. This receptor is mediated by G proteins that stimulate phospholipase C. |
Protein Length | 453 Amino acids |
Molecular weight | 50622 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7472509 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20360 |
Swiss-prot Accession number | Q16951 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2 receptor (5-HTB2) (Serotonin receptor 2). |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Central nervous system. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin). 5-HT plays important roles in various behavioral and physiological processes in aplysia. These include feeding, locomotion, circadian rhythm, learning and memory, synaptic plasticity, and synaptic growth. This receptor is mediated by G proteins that stimulate phospholipase C. |
Protein Length | 421 Amino acids |
Molecular weight | 47637 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7472509 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20361 |
Swiss-prot Accession number | Q17239 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor (5-HT receptor) (Serotonin receptor). |
Source organism | Bombyx mori (Silk moth) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen (By similarity). |
Protein Length | 446 Amino acids |
Molecular weight | 48599 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9014328 |
Hormone | N/A |
Gene ID | 693054 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20362 |
Swiss-prot Accession number | Q25190 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor (5-HT receptor) (Serotonin receptor). |
Source organism | Heliothis virescens (Noctuid moth) (Owlet moth) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;Noctuidae; Heliothinae; Heliothis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 52094 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9014328 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20363 |
Swiss-prot Accession number | Q25414 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor (5-HT receptor) (Serotonin receptor). |
Source organism | Lymnaea stagnalis (Great pond snail) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Pulmonata; Basommatophora;Lymnaeoidea; Lymnaeidae; Lymnaea. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is a receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen. |
Protein Length | 509 Amino acids |
Molecular weight | 56902 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8093556 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20364 |
Swiss-prot Accession number | O15969 (Sequence in FASTA format) |
Description | Serotonin receptor-like planarian receptor 4. |
Source organism | Dugesia japonica (Planarian) |
Taxonomical Classification | Eukaryota; Metazoa; Platyhelminthes; Turbellaria; Seriata; Tricladida;Paludicola; Dugesiidae; Dugesia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 478 Amino acids |
Molecular weight | 54598 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9300820 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20365 |
Swiss-prot Accession number | O17470 (Sequence in FASTA format) |
Description | Serotonin receptor (Serotonin/octopamine receptor family protein 1,isoform a). |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 683 Amino acids |
Molecular weight | 76200 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10098838 2 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 181716 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20366 |
Swiss-prot Accession number | O17496 (Sequence in FASTA format) |
Description | Serotonin receptor. |
Source organism | Ascaris suum (Pig roundworm) (Ascaris lumbricoides) |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Ascaridida; Ascaridoidea;Ascarididae; Ascaris. |
Subcellular location | Membrane (By similarity). |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 532 Amino acids |
Molecular weight | 60141 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10413046 2 PubMed abstract 12423236 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20367 |
Swiss-prot Accession number | O18512 (Sequence in FASTA format) |
Description | Serotonin receptor (Serotonin/octopamine receptor family protein 4). |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 445 Amino acids |
Molecular weight | 50142 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9061615 2 Dubnick M.; Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 175322 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20368 |
Swiss-prot Accession number | O61232 (Sequence in FASTA format) |
Description | Serotonin receptor 5-HT2. |
Source organism | Lymnaea stagnalis (Great pond snail) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Pulmonata; Basommatophora;Lymnaeoidea; Lymnaeidae; Lymnaea. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 885 Amino acids |
Molecular weight | 97577 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8891606 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20369 |
Swiss-prot Accession number | O76267 (Sequence in FASTA format) |
Description | G-protein-coupled 5-hydroxytryptamine receptor. |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 492 Amino acids |
Molecular weight | 56262 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9671650 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20370 |
Swiss-prot Accession number | P97842 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine7 receptor isoform c. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 470 Amino acids |
Molecular weight | 52099 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9084407 2 Heidmann D.E.A., Metcalf M.A., Kohen R., Hamblin M.W.; Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20371 |
Swiss-prot Accession number | Q24511 (Sequence in FASTA format) |
Description | Serotonin receptor 5-HT2 subtype. |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 868 Amino acids |
Molecular weight | 94957 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7777527 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20372 |
Swiss-prot Accession number | Q2MGS6 (Sequence in FASTA format) |
Description | Serotonin receptor. |
Source organism | Hemicentrotus pulcherrimus (Sea urchin) |
Taxonomical Classification | Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae;Hemicentrotus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 465 Amino acids |
Molecular weight | 51889 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 17234609 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20373 |
Swiss-prot Accession number | Q2PGF5 (Sequence in FASTA format) |
Description | 5-HT receptor. |
Source organism | Patinopecten yessoensis (Ezo giant scallop) (Yesso scallop) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Bivalvia; Pteriomorphia; Pectinoida;Pectinoidea; Pectinidae; Mizuhopecten. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 454 Amino acids |
Molecular weight | 50500 |
Domain Name | 7tm_1 |
References | 1 Osada M., Tanabe T., Kijima A.; "Isolation and characterization of cDNA encoding an 5-HT receptorprotein from the scallop, Patinopecten yessoensis."; Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20374 |
Swiss-prot Accession number | Q32Z81 (Sequence in FASTA format) |
Description | 5-HT1 receptor. |
Source organism | Penaeus monodon (Penoeid shrimp) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata; Penaeoidea;Penaeidae; Penaeus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 591 Amino acids |
Molecular weight | 63471 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16949686 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20375 |
Swiss-prot Accession number | Q3URB0 (Sequence in FASTA format) |
Description | Adult male hippocampus cDNA, RIKEN full-length enriched library,clone:C630048L11 product:5-hydroxytryptamine (serotonin) receptor 5A,full insert sequence (5-hydroxytryptamine (Serotonin) receptor 5A). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 357 Amino acids |
Molecular weight | 40736 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 12477932 10 Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases. 11 Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15563 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20376 |
Swiss-prot Accession number | Q3URB5 (Sequence in FASTA format) |
Description | Adult male hippocampus cDNA, RIKEN full-length enriched library,clone:C630046L14 product:5 hydroxytryptamine (serotonin) receptor 4,full insert sequence (Hypothetical protein) (Adult male hippocampuscDNA, RIKEN full-length enriched library, clone:C630036D03 product:5hydroxytryptamine (serotonin) receptor 4, full insert sequence). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 388 Amino acids |
Molecular weight | 43962 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 12477932 10 Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15562 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20377 |
Swiss-prot Accession number | Q3ZB48 (Sequence in FASTA format) |
Description | Htr1d protein (5-hydroxytryptamine (Serotonin) receptor 1D). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 374 Amino acids |
Molecular weight | 41566 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20378 |
Swiss-prot Accession number | Q4U3W8 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 7. |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 448 Amino acids |
Molecular weight | 49783 |
Domain Name | 7tm_1 |
References | 1 Amireault P., Dube F.; "Cloning and sequencing of a golden hamster 5-HT7 receptor cDNA."; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20379 |
Swiss-prot Accession number | Q4U3W9 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 2A. |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
Protein Length | 471 Amino acids |
Molecular weight | 52719 |
Domain Name | 7tm_1 |
References | 1 Amireault P., Dube F.; "Cloning and sequencing of a golden hamster 5-HT2A receptor cDNA."; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20380 |
Swiss-prot Accession number | Q50DZ8 (Sequence in FASTA format) |
Description | Serotonin 5HT2B receptor. |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 434 Amino acids |
Molecular weight | 49051 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15862800 |
Hormone | N/A |
Gene ID | 403881 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20381 |
Swiss-prot Accession number | Q543D4 (Sequence in FASTA format) |
Description | 0 day neonate lung cDNA, RIKEN full-length enriched library,clone:E030013E04 product:5-hydroxytryptamine (serotonin) receptor 2 A,full insert sequence (5-hydroxytryptamine (Serotonin) receptor 2A). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
Protein Length | 471 Amino acids |
Molecular weight | 52842 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 12477932 10 Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15558 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20382 |
Swiss-prot Accession number | Q543V2 (Sequence in FASTA format) |
Description | Adult male corpora quadrigemina cDNA, RIKEN full-length enrichedlibrary, clone:B230106O20 product:5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR) (5-HT-1E-BETA), full insert sequence (5-hydroxytryptamine (Serotonin) receptor 1F). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 366 Amino acids |
Molecular weight | 41977 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 12477932 10 Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15557 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20383 |
Swiss-prot Accession number | Q546Q1 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine4 receptor (5-hydroxytryptamine (Serotonin)receptor 4) (Serotonin receptor 5-HT4). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 388 Amino acids |
Molecular weight | 43761 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11750916 2 PubMed abstract 12477932 3 Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. 4 Syversveen T., Bach T., Kvingedal A.M., Krobert K.A., Kaumann A.J.,Levy F.O.; "Molecular cloning of the human serotonin receptor 5-HT4(b) andpharmacological comparison with the cloned human 5-HT4(a) receptor."; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 3360 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20384 |
Swiss-prot Accession number | Q5E9Q5 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine (Serotonin) receptor 4 isoform b. |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 402 Amino acids |
Molecular weight | 45366 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11282978 2 Harhay G.P., Sonstegard T.S., Clawson M.L., Heaton M.P., Keele J.W.,Snelling W.M., Weidmann R.T., Smith T.P.L.; "Sequencing and analysis of Bos taurus full-length insert cDNAclones."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 317708 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20385 |
Swiss-prot Accession number | Q5TGZ1 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine (Serotonin) receptor 6. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 440 Amino acids |
Molecular weight | 46954 |
Domain Name | 7tm_1 |
References | 1 Lad H.; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20386 |
Swiss-prot Accession number | Q5TLF3 (Sequence in FASTA format) |
Description | Serotonin receptor. |
Source organism | Papilio xuthus |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia;Papilionoidea; Papilionidae; Papilioninae; Papilio. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 466 Amino acids |
Molecular weight | 52015 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15544938 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20387 |
Swiss-prot Accession number | Q5VX01 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 432 Amino acids |
Molecular weight | 47984 |
Domain Name | 7tm_1 |
References | 1 Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20388 |
Swiss-prot Accession number | Q5VX02 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 445 Amino acids |
Molecular weight | 49488 |
Domain Name | 7tm_1 |
References | 1 Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 3363 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20389 |
Swiss-prot Accession number | Q5VX03 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 479 Amino acids |
Molecular weight | 53555 |
Domain Name | 7tm_1 |
References | 1 Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 3363 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20390 |
Swiss-prot Accession number | Q5VX04 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine (Serotonin) receptor 7 (Adenylate cyclase-coupled). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 479 Amino acids |
Molecular weight | 53567 |
Domain Name | 7tm_1 |
References | 1 Whitehead S.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20391 |
Swiss-prot Accession number | Q5ZGX3 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 1A. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 422 Amino acids |
Molecular weight | 46107 |
Domain Name | 7tm_1 |
References | 1 Patra A.K., Saravanan T., Aarthi R., Chugh A.; "Amplification and cloning of serotonin receptor, 5-hydroxy tryptaminereceptor 1A from Indian blood."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
2 Patra S.K.; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 3350 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20392 |
Swiss-prot Accession number | Q63004 (Sequence in FASTA format) |
Description | 5-HT6 serotonin receptor. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 438 Amino acids |
Molecular weight | 46786 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8522988 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20393 |
Swiss-prot Accession number | Q684M0 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 4 receptor isoform g2 (Serotonin receptor 5- HT4). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 378 Amino acids |
Molecular weight | 42746 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15118808 |
Hormone | N/A |
Gene ID | 3360 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20394 |
Swiss-prot Accession number | Q6EX43 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 5A. |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 356 Amino acids |
Molecular weight | 40141 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15212962 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20395 |
Swiss-prot Accession number | Q6JKS9 (Sequence in FASTA format) |
Description | Type 7 serotonin receptor. |
Source organism | Helisoma trivolvis (Snail) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Pulmonata; Basommatophora;Lymnaeoidea; Planorbidae; Helisoma. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 479 Amino acids |
Molecular weight | 53472 |
Domain Name | 7tm_1 |
References | 1 Mapara S., Parries S.C., Goldberg J.I., Gallin W.J.; "Cloning, phylogenetic analysis and localization of two serotoninreceptors from the pond snail Helisoma trivolvis."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20396 |
Swiss-prot Accession number | Q6Q253 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine receptor 4 protein. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 402 Amino acids |
Molecular weight | 45013 |
Domain Name | 7tm_1 |
References | 1 Zhao W., Meng H., Pan y.; "Cloning and expression analysis of the pig 5-HT4 serotonin receptorgene."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 397431 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20397 |
Swiss-prot Accession number | Q6QR16 (Sequence in FASTA format) |
Description | Type 1 serotonin receptor. |
Source organism | Panulirus interruptus (California spiny lobster) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Crustacea; Malacostraca;Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Palinura;Palinuroidea; Palinuridae; Panulirus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 435 Amino acids |
Molecular weight | 47869 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15116388 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20398 |
Swiss-prot Accession number | Q6TKQ2 (Sequence in FASTA format) |
Description | Type 1 serotonin receptor 5HT-1Hel. |
Source organism | Helisoma trivolvis (Snail) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Pulmonata; Basommatophora;Lymnaeoidea; Planorbidae; Helisoma. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 504 Amino acids |
Molecular weight | 56407 |
Domain Name | 7tm_1 |
References | 1 Mapara S., Parries S.C., Goldberg J.I., Gallin W.J.; "Cloning, phylogenetic analysis and localization of two serotoninreceptors from the pond snail Helisoma trivolvis."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20399 |
Swiss-prot Accession number | Q6XPX1 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1D receptor. |
Source organism | Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 385 Amino acids |
Molecular weight | 42740 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16356746 2 Tsai C.-L., Wang L.-H.; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20400 |
Swiss-prot Accession number | Q6XPX2 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor. |
Source organism | Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 416 Amino acids |
Molecular weight | 47043 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16356746 2 Tsai C.-L., Wang L.-H.; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20401 |
Swiss-prot Accession number | Q712M9 (Sequence in FASTA format) |
Description | Serotonin receptor 5-HT4. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 428 Amino acids |
Molecular weight | 48255 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15118808 |
Hormone | N/A |
Gene ID | 3360 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20402 |
Swiss-prot Accession number | Q7KPZ5 (Sequence in FASTA format) |
Description | Serotonin receptor (Serotonin/octopamine receptor family protein 1,isoform b). |
Source organism | Caenorhabditis elegans |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea;Rhabditidae; Peloderinae; Caenorhabditis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 635 Amino acids |
Molecular weight | 70854 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10098838 2 PubMed abstract 9851916 |
Hormone | N/A |
Gene ID | 181716 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20403 |
Swiss-prot Accession number | Q7QB24 (Sequence in FASTA format) |
Description | ENSANGP00000012908. |
Source organism | Anopheles gambiae str. PEST |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;Anophelinae; Anopheles. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 475 Amino acids |
Molecular weight | 52100 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12364791 2 PubMed abstract 14747013 3 Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.; "Update of the Anopheles gambiae PEST genome assembly, AgamP3."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 4 Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 1274064 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20404 |
Swiss-prot Accession number | Q7QK99 (Sequence in FASTA format) |
Description | ENSANGP00000013461. |
Source organism | Anopheles gambiae str. PEST |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;Anophelinae; Anopheles. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 473 Amino acids |
Molecular weight | 52353 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12364791 2 PubMed abstract 14747013 3 Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.; "Update of the Anopheles gambiae PEST genome assembly, AgamP3."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 4 Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 1269329 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20405 |
Swiss-prot Accession number | Q7SZL3 (Sequence in FASTA format) |
Description | 5HT2B serotonin receptor. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 453 Amino acids |
Molecular weight | 50657 |
Domain Name | 7tm_1 |
References | 1 De Lucchini S., Ori M., Nardini M., Marracci S., Nardi I.; "Expression of 5HT-2B and 5HT-2C receptor genes is associated withproliferative regions of Xenopus developing brain and eye."; Mol. Brain Res. 115:192-201(2003).
|
Hormone | N/A |
Gene ID | 398699 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20406 |
Swiss-prot Accession number | Q7ZZ32 (Sequence in FASTA format) |
Description | Novel protein similar to human 5-hydroxytryptamine (Serotonin)receptor 5A (HTR5A) (5-hydroxytryptamine (Serotonin) receptor 5Alike). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 346 Amino acids |
Molecular weight | 39412 |
Domain Name | 7tm_1 |
References | 1 Corby N.; Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 12477932 3 Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 100149438 368475 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20407 |
Swiss-prot Accession number | Q86LL7 (Sequence in FASTA format) |
Description | Serotonin receptor protein. |
Source organism | Haemonchus contortus (Barber pole worm) |
Taxonomical Classification | Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Strongylida;Trichostrongyloidea; Haemonchidae; Haemonchinae; Haemonchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 439 Amino acids |
Molecular weight | 49290 |
Domain Name | 7tm_1 |
References | 1 Smith M.W., Borts T.L., Emkey R., Cook C.A., Wiggins C.J.,Gutierrez J.A.; "Characterization of a novel G-protein coupled receptor from theparasitic nematode Haemonchus contortus with high affinity forserotonin."; Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20408 |
Swiss-prot Accession number | Q8BGS4 (Sequence in FASTA format) |
Description | 10 days neonate cortex cDNA, RIKEN full-length enriched library,clone:A830017H24 product:5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A)(SEROTONIN RECEPTOR) (5- HT1A), full insert sequence (Adult malecorpora quadrigemina cDNA, RIKEN full-length enriched library,clone:B230339C01 product:5-hydroxytryptamine (serotonin) receptor 1A,full insert sequence) (Adult male hippocampus cDNA, RIKEN full-lengthenriched library, clone:C630007E24 product:5-HYDROXYTRYPTAMINE 1ARECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A), full insertsequence) (Adult male hippocampus cDNA, RIKEN full-length enrichedlibrary, clone:C630001G15 product:5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A) (SEROTONIN RECEPTOR) (5- HT1A), full insert sequence). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 421 Amino acids |
Molecular weight | 46176 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 9 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15550 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20409 |
Swiss-prot Accession number | Q8BUW7 (Sequence in FASTA format) |
Description | 16 days embryo head cDNA, RIKEN full-length enriched library,clone:C130095B09 product:5-HYDROXYTRYPTAMINE 1D RECEPTOR (5-HT-1D)(SEROTONIN RECEPTOR), full insert sequence (5-hydroxytryptamine(Serotonin) receptor 1D). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 374 Amino acids |
Molecular weight | 41594 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 9 Pearce A.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15552 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20410 |
Swiss-prot Accession number | Q8BZI5 (Sequence in FASTA format) |
Description | Adult male diencephalon cDNA, RIKEN full-length enriched library,clone:9330209K16 product:5-HYDROXYTRYPTAMINE 2C RECEPTOR, full insertsequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 459 Amino acids |
Molecular weight | 51915 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 15560 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20411 |
Swiss-prot Accession number | Q8BZP1 (Sequence in FASTA format) |
Description | Adult male diencephalon cDNA, RIKEN full-length enriched library,clone:9330141D13 product:5-HYDROXYTRYPTAMINE 1A RECEPTOR (5-HT-1A)(SEROTONIN RECEPTOR) (5- HT1A), full insert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 421 Amino acids |
Molecular weight | 46185 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20412 |
Swiss-prot Accession number | Q8HYB0 (Sequence in FASTA format) |
Description | Serotonin receptor 1A. |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 423 Amino acids |
Molecular weight | 46399 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12692162 2 PubMed abstract 16251523 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20413 |
Swiss-prot Accession number | Q8IXH9 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 4 receptor subunit b. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 388 Amino acids |
Molecular weight | 43789 |
Domain Name | 7tm_1 |
References | 1 Bruss M., Bonisch H.; "Molecular cloning and pharmacological characterization of human 5-HT4-like receptors."; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
2 Bruess M.; Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20414 |
Swiss-prot Accession number | Q8MX83 (Sequence in FASTA format) |
Description | G-protein-coupled 5-hydroxytryptamine receptor 2. |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 567 Amino acids |
Molecular weight | 63167 |
Domain Name | 7tm_1 |
References | 1 Barbas D., Zappulla J.P., Angers S., Bouvier M., Castellucci V.F.,DesGroseillers L.; "Molecular characterization of a new serotoninergic receptornegatively coupled to adenylate cyclase in Aplysia californica."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20415 |
Swiss-prot Accession number | Q8SPH2 (Sequence in FASTA format) |
Description | Serotonin 5-hydroxytryptamine 7-a receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 447 Amino acids |
Molecular weight | 49677 |
Domain Name | 7tm_1 |
References | 1 Bhalla P., Saxena P.R., Sharma H.S.; "Molecular Cloning and Tissue Distribution of Porcine 5-HT7receptor."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 397158 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20416 |
Swiss-prot Accession number | Q8UUG8 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2B receptor (5-HT-2B) (Serotonin receptor 2B). |
Source organism | Tetraodon fluviatilis (Puffer fish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Detected in brain, heart and gut. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 471 Amino acids |
Molecular weight | 53057 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11744166 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20417 |
Swiss-prot Accession number | Q98998 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5-HT1A) (X5-HT1A). |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | First expressed in the rostral part of the brain stem at stage 22. At later stages of development, expression is localized to serotonergic neurons. The expression pattern changes in the tadpole of stage 41 where, in addition to serotonergic neurons, expression is also localized to the inner nuclear layer (INL) of the developing retina. This expression pattern continues through to the start of metamorphosis (stage 46). In adults, expressed in the brain, in particular the telencephalon, diencephalon and mesencephalon. In the telencephalic region, expression is localized to the lateral, dorsal and medial pallium, and in the striatum, septum and amygdala. In the mesencephalic region, expression is strongest in the optic tectum and torus semicircularis with moderate levels of expression in tegmental nuclei. In diencephalon, localized to the dorsal and ventral thalamus and the preoptic area of the hypothalamus. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Activation of the receptor may play a role in the exit from G0 phase and in promoting DNA synthesis. |
Protein Length | 408 Amino acids |
Molecular weight | 45788 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9221903 2 PubMed abstract 9878840 |
Hormone | N/A |
Gene ID | 378605 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20418 |
Swiss-prot Accession number | Q99MB0 (Sequence in FASTA format) |
Description | Serotonin receptor 5HT1B. |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 386 Amino acids |
Molecular weight | 43021 |
Domain Name | 7tm_1 |
References | 1 Devor E.J., Devor R.M.; "Cloning and sequencing the serotonin receptor 5HT1B in the GoldenHamster."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20419 |
Swiss-prot Accession number | Q9GLP5 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1B receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 390 Amino acids |
Molecular weight | 43418 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11454663 |
Hormone | N/A |
Gene ID | 397563 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20421 |
Swiss-prot Accession number | Q9QW77 (Sequence in FASTA format) |
Description | 5-HT2 RECEPTOR=SEROTONINERGIC receptor. |
Source organism | Cricetulus griseus (Chinese hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Cricetulus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production (By similarity). |
Protein Length | 471 Amino acids |
Molecular weight | 52856 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1944295 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20423 |
Swiss-prot Accession number | Q16144 (Sequence in FASTA format) |
Description | Cholecystokinin B receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 447 Amino acids |
Molecular weight | 48418 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8185170 2 PubMed abstract 7887934 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20424 |
Swiss-prot Accession number | Q92492 (Sequence in FASTA format) |
Description | Cholecystokinin-B receptor/gastrin receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 447 Amino acids |
Molecular weight | 48419 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8349705 2 PubMed abstract 7848914 3 PubMed abstract 8222757 4 PubMed abstract 7887934 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20425 |
Swiss-prot Accession number | Q96LC6 (Sequence in FASTA format) |
Description | CCK-B/gastrin receptor variant (Cholecystokinin-C receptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 516 Amino acids |
Molecular weight | 55841 |
Domain Name | 7tm_1 |
References | 1 Schmitz F., Schrader H., Stueber E., Schmidt W.E.; "Identification of CCK-B/gastrin receptor splice variants in humanperipheral blood mononuclear cells."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 7887934 3 PubMed abstract 12429993 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20426 |
Swiss-prot Accession number | P41968 (Sequence in FASTA format) |
Description | Melanocortin receptor 3 (MC3-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain, placental, and gut tissues. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 360 Amino acids |
Molecular weight | 40073 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8463333 2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 11780052 4 PubMed abstract 15489334 5 PubMed abstract 8463333 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 11780052 8 PubMed abstract 15489334 |
Hormone | N/A |
Gene ID | 4159 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20427 |
Swiss-prot Accession number | P33033 (Sequence in FASTA format) |
Description | Melanocortin receptor 3 (MC3-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 323 Amino acids |
Molecular weight | 35806 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8172596 |
Hormone | N/A |
Gene ID | 17201 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20428 |
Swiss-prot Accession number | P32244 (Sequence in FASTA format) |
Description | Melanocortin receptor 3 (MC3-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. |
Protein Length | 323 Amino acids |
Molecular weight | 35866 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8415620 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20429 |
Swiss-prot Accession number | Q9GLJ8 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 332 Amino acids |
Molecular weight | 36620 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11531696 |
Hormone | N/A |
Gene ID | 281300 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20430 |
Swiss-prot Accession number | P32245 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain, placental, and gut tissues. |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 332 Amino acids |
Molecular weight | 36943 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8392067 2 PubMed abstract 7854347 3 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15489334 5 PubMed abstract 10199800 6 PubMed abstract 11443223 7 PubMed abstract 8392067 8 PubMed abstract 7854347 9 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 10 PubMed abstract 15489334 11 PubMed abstract 10199800 12 PubMed abstract 11443223 |
Hormone | N/A |
Gene ID | 4160 |
PDB ID | 2IQP 2IQR 2IQS 2IQU 2IQV 2IQW |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20431 |
Swiss-prot Accession number | Q8HXX3 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Macaca fascicularis (Crab eating macaque) (Cynomolgus monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 332 Amino acids |
Molecular weight | 37002 |
Domain Name | 7tm_1 |
References | 1 Kusuda J., Osada N., Hida M., Sugano S., Hashimoto K.; "Isolation and characterization of cDNA for macaque neurologicaldisease genes."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20432 |
Swiss-prot Accession number | P56450 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 332 Amino acids |
Molecular weight | 36989 |
Domain Name | 7tm_1 |
References | 1 Dumont L.M., Wu C.S., Mountjoy K.G.; "Characterization of the melanocortin-4 receptor gene."; Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
2 Morooka Y., Oomizu S., Takeuchi S., Takahashi S.; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20433 |
Swiss-prot Accession number | O97504 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase (By similarity). |
Protein Length | 332 Amino acids |
Molecular weight | 36947 |
Domain Name | 7tm_1 |
References | 1 Ito Y., Minezawa M.; Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 10656927 3 Matteri R.L., Dyer C.J.; Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 397359 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20434 |
Swiss-prot Accession number | P70596 (Sequence in FASTA format) |
Description | Melanocortin receptor 4 (MC4-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain, enriched in the striatum, nucleus accumbens, and periaqueductal gray. |
Post translational modification | N/A |
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase. |
Protein Length | 332 Amino acids |
Molecular weight | 36887 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8794897 |
Hormone | N/A |
Gene ID | 25635 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20435 |
Swiss-prot Accession number | P56451 (Sequence in FASTA format) |
Description | Melanocortin receptor 5 (MC5-R). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins (By similarity). |
Protein Length | 325 Amino acids |
Molecular weight | 36526 |
Domain Name | 7tm_1 |
References | 1 Oulmouden A., Petit J.-M., Julien R.; Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 507987 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20436 |
Swiss-prot Accession number | P33032 (Sequence in FASTA format) |
Description | Melanocortin receptor 5 (MC5-R) (MC-2). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in the brain but not in the melanoma cells. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
Protein Length | 325 Amino acids |
Molecular weight | 36601 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8396929 2 PubMed abstract 8179577 3 PubMed abstract 7739752 4 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15489334 6 PubMed abstract 9240466 7 PubMed abstract 11286624 |
Hormone | N/A |
Gene ID | 4161 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20437 |
Swiss-prot Accession number | P41149 (Sequence in FASTA format) |
Description | Melanocortin receptor 5 (MC5-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Skin, adrenal gland, skeletal muscle, bone marrow, spleen, thymus, gonads, uterus and brain. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
Protein Length | 325 Amino acids |
Molecular weight | 36953 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8161509 2 PubMed abstract 8185570 3 PubMed abstract 7739752 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20438 |
Swiss-prot Accession number | Q9TT23 (Sequence in FASTA format) |
Description | Melanocortin receptor 5 (MC5-R). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
Protein Length | 325 Amino acids |
Molecular weight | 36647 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11286624 |
Hormone | N/A |
Gene ID | 468599 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20439 |
Swiss-prot Accession number | P35345 (Sequence in FASTA format) |
Description | Melanocortin receptor 5 (MC5-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Very low expression levels is detected in brain, while high levels are found in adrenals, stomach, lung and spleen. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
Protein Length | 325 Amino acids |
Molecular weight | 37050 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8179577 |
Hormone | N/A |
Gene ID | 25726 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20440 |
Swiss-prot Accession number | P41983 (Sequence in FASTA format) |
Description | Melanocortin receptor 5 (MC5-R). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. |
Protein Length | 325 Amino acids |
Molecular weight | 36585 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8060485 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20441 |
Swiss-prot Accession number | O57317 (Sequence in FASTA format) |
Description | Melanocortin 2-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 357 Amino acids |
Molecular weight | 40615 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9622604 |
Hormone | N/A |
Gene ID | 428516 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20442 |
Swiss-prot Accession number | O73667 (Sequence in FASTA format) |
Description | Melanocortin 4-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 331 Amino acids |
Molecular weight | 36984 |
Domain Name | 7tm_1 |
References | 1 Takeuchi S., Takahashi S.; "Molecular cloning of the chicken melanocortin 4-receptor gene widelyexpressed in peripheral tissues."; Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20443 |
Swiss-prot Accession number | O73671 (Sequence in FASTA format) |
Description | Melanocortin 5-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 325 Amino acids |
Molecular weight | 36995 |
Domain Name | 7tm_1 |
References | 1 Takeuchi S., Takahashi S.; "Cloning and expression of the chicken melanocortin 5-receptor gene."; Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 421047 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20444 |
Swiss-prot Accession number | O93259 (Sequence in FASTA format) |
Description | Melanocortin 3-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 325 Amino acids |
Molecular weight | 36601 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9990303 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20445 |
Swiss-prot Accession number | Q2EF33 (Sequence in FASTA format) |
Description | MC4R. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 332 Amino acids |
Molecular weight | 36947 |
Domain Name | 7tm_1 |
References | 1 Yang X.Q., Yu H., Liu D.; "The comparative analysis on MC4R gene of wild boar, domestic pig andtheir crossbred."; Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20446 |
Swiss-prot Accession number | Q2M499 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34622 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20447 |
Swiss-prot Accession number | Q2M4A0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34620 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20448 |
Swiss-prot Accession number | Q2M4A2 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34576 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20449 |
Swiss-prot Accession number | Q2M4A3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34624 |
Domain Name | 7tm_1 |
References | 1 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20450 |
Swiss-prot Accession number | Q3HW23 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa coreanus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34675 |
Domain Name | 7tm_1 |
References | 1 Cho I.-C., Han S.-H., Hwang J.-H., Jeon J.-T., Andersson L.; "Genetic Variation of MC1R gene in Korean wild boar."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20451 |
Swiss-prot Accession number | Q3HW26 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa coreanus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34592 |
Domain Name | 7tm_1 |
References | 1 Cho I.-C., Han S.-H., Hwang J.-H., Jeon J.-T., Andersson L.; "Genetic Variation of MC1R gene in Korean wild boar."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20452 |
Swiss-prot Accession number | Q3ZAT4 (Sequence in FASTA format) |
Description | Melanocortin 3 receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 323 Amino acids |
Molecular weight | 35830 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20453 |
Swiss-prot Accession number | Q45RC1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34608 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16978185 2 Xu G., Ren J., Ma J., Huang L.; Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. 3 Ju Y.-T., Chang W.-H., Chu H.-P.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. 4 Du Z.Q., Vincent-Naulleau S., Gilbert H., Vignoles F.; "Detection of novel quantitative trait loci for cutaneous melanoma bygenome-wide scan in the MeLiM swine model."; Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases. 5 Geffrotin C.; Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 17150979 7 Lai F.-J., Ren J., Ai H.-S., Ding N.-S., Ma J.-W., Chen C.-Y.,Guo Y.-M., Huang L.-S.; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 8 Xu G., Ren J., Ma J., Ding N., Guo Y., Chen C., Huang L.; Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20454 |
Swiss-prot Accession number | Q496T0 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 372 Amino acids |
Molecular weight | 42186 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 17203 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20458 |
Swiss-prot Accession number | Q4KXA4 (Sequence in FASTA format) |
Description | Melanocortin 3 receptor. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 323 Amino acids |
Molecular weight | 35757 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15985309 |
Hormone | N/A |
Gene ID | 29310 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20459 |
Swiss-prot Accession number | Q502V1 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 325 Amino acids |
Molecular weight | 36567 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20460 |
Swiss-prot Accession number | Q533M5 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Taricha granulosa (Roughskin newt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Caudata; Salamandroidea; Salamandridae; Taricha. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 346 Amino acids |
Molecular weight | 39433 |
Domain Name | 7tm_1 |
References | 1 Walthers E.A., Moore F.L.; "Molecular Cloning of a Melanocortin 5 Receptor (Mc5r) from the Brainof an Amphibian, the Rough-Skinned Newt Taricha granulosa."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20461 |
Swiss-prot Accession number | Q533M6 (Sequence in FASTA format) |
Description | Melanocortin 3 receptor. |
Source organism | Taricha granulosa (Roughskin newt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Caudata; Salamandroidea; Salamandridae; Taricha. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 322 Amino acids |
Molecular weight | 36334 |
Domain Name | 7tm_1 |
References | 1 Walthers E.A., Moore F.L.; "Molecular Cloning of a Melanocortin 3 Receptor (Mc3r) from the Brainof an Amphibian, the Rough-Skinned Newt Taricha granulosa."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20462 |
Swiss-prot Accession number | Q544G7 (Sequence in FASTA format) |
Description | Adult male hypothalamus cDNA, RIKEN full-length enriched library,clone:A230054D12 product:MELANOCORTIN-3 RECEPTOR (MC3-R), full insertsequence (Melanocortin 3 receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 323 Amino acids |
Molecular weight | 35806 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 9 Holt K.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. 10 PubMed abstract 12477932 11 Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 17201 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20463 |
Swiss-prot Accession number | Q544P9 (Sequence in FASTA format) |
Description | 15 days embryo male testis cDNA, RIKEN full-length enriched library,clone:8030422J23 product:ADRENOCORTICOTROPIC HORMONE RECEPTOR, fullinsert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 296 Amino acids |
Molecular weight | 33982 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 17200 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20464 |
Swiss-prot Accession number | Q59I35 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coturnix coturnix japonica (Japanese quail) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Coturnix. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35456 |
Domain Name | 7tm_1 |
References | 1 Wada A., Tsudzuki M.; "Nucleotide polymorphisms at the Mc1r locus of poultry."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20465 |
Swiss-prot Accession number | Q59I36 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coturnix coturnix japonica (Japanese quail) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Coturnix. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35443 |
Domain Name | 7tm_1 |
References | 1 Wada A., Tsudzuki M.; "Nucleotide polymorphisms at the Mc1r locus of poultry."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20466 |
Swiss-prot Accession number | Q59I38 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coturnix chinensis (Blue-breasted quail) (Excalfactoria chinensis) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Coturnix. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 313 Amino acids |
Molecular weight | 35361 |
Domain Name | 7tm_1 |
References | 1 Wada A., Tsudzuki M.; "Nucleotide polymorphisms at the Mc1r locus of poultry."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20467 |
Swiss-prot Accession number | Q59I39 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35364 |
Domain Name | 7tm_1 |
References | 1 Wada A., Tsudzuki M.; "Nucleotide polymorphisms at the Mc1r locus of poultry."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 427562 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20468 |
Swiss-prot Accession number | Q5K034 (Sequence in FASTA format) |
Description | Putative melanocortin-1-receptor, mc1R. |
Source organism | Oreochromis mossambicus (Mozambique tilapia) (Tilapia mossambica) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 325 Amino acids |
Molecular weight | 36939 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16019002 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20469 |
Swiss-prot Accession number | Q66K38 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor (Alpha melanocyte stimulating hormonereceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34652 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. 3 Nakayama K., Soemantri A., Jin F., Dashnyam B., Ohtsuka R.,Duanchang P., Isa M.N., Ishida W.S., Harihara S., Ishida T.; "Identification of novel functional variants of the melanocortin 1receptor gene originated from Asians."; Hum. Genet. 0:0-0(2006). |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20470 |
Swiss-prot Accession number | Q66XM4 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Uta stansburiana (Side-blotched lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae; Uta. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35539 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20471 |
Swiss-prot Accession number | Q66XM6 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Uta stansburiana (Side-blotched lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae; Uta. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35622 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20474 |
Swiss-prot Accession number | Q66XP5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35475 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20475 |
Swiss-prot Accession number | Q66XP9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35699 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20476 |
Swiss-prot Accession number | Q66XQ4 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35774 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20477 |
Swiss-prot Accession number | Q66XQ6 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35713 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20478 |
Swiss-prot Accession number | Q66XR0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35671 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20479 |
Swiss-prot Accession number | Q66XU4 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35647 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20480 |
Swiss-prot Accession number | Q66XV1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35687 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20481 |
Swiss-prot Accession number | Q66XV3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35697 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20482 |
Swiss-prot Accession number | Q66XV8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35651 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20483 |
Swiss-prot Accession number | Q66XW8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35727 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20484 |
Swiss-prot Accession number | Q66XX0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35685 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20485 |
Swiss-prot Accession number | Q66XX3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sceloporus undulatus (Eastern fence lizard) (Skink) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Sceloporus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35673 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20486 |
Swiss-prot Accession number | Q66XX7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Phrynosoma platyrhinos (Desert horned lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Phrynosoma. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35657 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20487 |
Swiss-prot Accession number | Q66XY3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Phrynosoma platyrhinos (Desert horned lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Phrynosoma. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35633 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20488 |
Swiss-prot Accession number | Q66XY7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35836 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20489 |
Swiss-prot Accession number | Q66XZ0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35794 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20490 |
Swiss-prot Accession number | Q66XZ4 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35796 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20491 |
Swiss-prot Accession number | Q66XZ9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35823 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20492 |
Swiss-prot Accession number | Q66Y36 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35727 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20493 |
Swiss-prot Accession number | Q66Y45 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35589 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20494 |
Swiss-prot Accession number | Q66Y53 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35725 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20495 |
Swiss-prot Accession number | Q66Y55 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35744 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20496 |
Swiss-prot Accession number | Q66Y65 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35740 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20497 |
Swiss-prot Accession number | Q66Y67 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35757 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20498 |
Swiss-prot Accession number | Q66Y70 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35480 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20499 |
Swiss-prot Accession number | Q66Y72 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35713 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20500 |
Swiss-prot Accession number | Q66Y75 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Holbrookia maculata (Lesser earless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Iguania; Iguanidae; Phrynosomatinae;Holbrookia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 315 Amino acids |
Molecular weight | 35574 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20501 |
Swiss-prot Accession number | Q66Y82 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Aspidoscelis inornata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Teiioidea;Teiidae; Aspidoscelis; Aspidoscelis sexlineata group. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35604 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20502 |
Swiss-prot Accession number | Q66Y90 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Aspidoscelis inornata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Teiioidea;Teiidae; Aspidoscelis; Aspidoscelis sexlineata group. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35606 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20503 |
Swiss-prot Accession number | Q66YC1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Aspidoscelis inornata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Teiioidea;Teiidae; Aspidoscelis; Aspidoscelis sexlineata group. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35545 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20504 |
Swiss-prot Accession number | Q66YD4 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Aspidoscelis inornata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Teiioidea;Teiidae; Aspidoscelis; Aspidoscelis sexlineata group. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35547 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20505 |
Swiss-prot Accession number | Q66YH0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Aspidoscelis inornata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Teiioidea;Teiidae; Aspidoscelis; Aspidoscelis sexlineata group. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35495 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20506 |
Swiss-prot Accession number | Q66YI5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Aspidoscelis inornata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Scincomorpha; Teiioidea;Teiidae; Aspidoscelis; Aspidoscelis sexlineata group. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35535 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20507 |
Swiss-prot Accession number | Q66YJ5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Anniella pulchra (California legless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Anguimorpha; Anguidae;Anniellinae; Anniella. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 306 Amino acids |
Molecular weight | 34481 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20508 |
Swiss-prot Accession number | Q66YK1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Anniella pulchra (California legless lizard) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Anguimorpha; Anguidae;Anniellinae; Anniella. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 306 Amino acids |
Molecular weight | 34447 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15446431 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20509 |
Swiss-prot Accession number | Q6E126 (Sequence in FASTA format) |
Description | Melanocortin-1 receptor. |
Source organism | Malurus leucopterus leuconotus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Maluridae; Malurus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 285 Amino acids |
Molecular weight | 31820 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15306285 2 Rathburn M.K., Montgomerie R.; Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20510 |
Swiss-prot Accession number | Q6E6M5 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 331 Amino acids |
Molecular weight | 36996 |
Domain Name | 7tm_1 |
References | 1 Qiu X., Li N.; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 428485 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20511 |
Swiss-prot Accession number | Q6E6M6 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 331 Amino acids |
Molecular weight | 37083 |
Domain Name | 7tm_1 |
References | 1 Qiu X., Li N.; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20512 |
Swiss-prot Accession number | Q6Q3F8 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Squalus acanthias (Spiny dogfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Squalea; Hypnosqualea; Squaliformes; Squaloidei;Squalidae; Squalus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 324 Amino acids |
Molecular weight | 36372 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15511238 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20518 |
Swiss-prot Accession number | Q6UR92 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant V265I. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34720 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20519 |
Swiss-prot Accession number | Q6UR93 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant A222T. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34736 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20520 |
Swiss-prot Accession number | Q6UR94 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant A111V. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34734 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20521 |
Swiss-prot Accession number | Q6UR95 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant C315R. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34759 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20522 |
Swiss-prot Accession number | Q6UR96 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant T308M. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34736 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20523 |
Swiss-prot Accession number | Q6UR97 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant R213W. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34736 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20524 |
Swiss-prot Accession number | Q6UR98 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant R160Q. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34677 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20525 |
Swiss-prot Accession number | Q6UR99 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant S83L. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34732 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20526 |
Swiss-prot Accession number | Q6URA0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant F45L. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34671 |
Domain Name | 7tm_1 |
References | 1 Pastorino L., Cusano R., Lantieri F., Origone P., Bruno W., Barile M.,Gliori S., Sturm R.A., Bianchi Scarra' G.; "Novel MC1R variants in Ligurian melanoma patients and controls."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20527 |
Swiss-prot Accession number | Q6VQ97 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 340 Amino acids |
Molecular weight | 38220 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14694081 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20528 |
Swiss-prot Accession number | Q6VQ98 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 323 Amino acids |
Molecular weight | 35926 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14694081 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20529 |
Swiss-prot Accession number | Q6VQ99 (Sequence in FASTA format) |
Description | Melanocortin 2 receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 303 Amino acids |
Molecular weight | 34690 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14694081 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20530 |
Swiss-prot Accession number | Q6VQA0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 325 Amino acids |
Molecular weight | 37044 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14694081 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20531 |
Swiss-prot Accession number | Q70JV5 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 329 Amino acids |
Molecular weight | 37248 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14713292 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20534 |
Swiss-prot Accession number | Q78DJ5 (Sequence in FASTA format) |
Description | Melanocortin receptor-4. |
Source organism | Takifugu chinensis |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 322 Amino acids |
Molecular weight | 35975 |
Domain Name | 7tm_1 |
References | 1 Kunimoto M., Mizukami Y.; "Discrimination of Takifugu species based on melanocortin receptor-1gene nucleotide sequence."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20535 |
Swiss-prot Accession number | Q7T0K6 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Squalus acanthias (Spiny dogfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Squalea; Hypnosqualea; Squaliformes; Squaloidei;Squalidae; Squalus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 331 Amino acids |
Molecular weight | 37094 |
Domain Name | 7tm_1 |
References | 1 Ringholm A.I., Klovins J., Fredriksson R., Poliakova N., Larson E.T.,Kukkonen J.P., Larhammar D., Schioeth H.B.; "Presence of melanocortin (MC4) receptor in spiny dogfish suggests anancient vertebrate origin of central MC system."; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20536 |
Swiss-prot Accession number | Q7T3U3 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 326 Amino acids |
Molecular weight | 36542 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12746294 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20537 |
Swiss-prot Accession number | Q7YSE7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34718 |
Domain Name | 7tm_1 |
References | 1 Fukuzaki U., Kubo Y., Ishishita S., Tsuruma N., Takeuchi S.,Nishida-Umehara C., Ando J., Matsuda Y., Yamamoto H.; "Molecular cloning and chromosomal localization of the feline MC1Rgene."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 493917 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20538 |
Swiss-prot Accession number | Q7ZSX7 (Sequence in FASTA format) |
Description | Melanocortin 2 receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 301 Amino acids |
Molecular weight | 34655 |
Domain Name | 7tm_1 |
References | 1 Logan D.W., Bryson-Richardson R.J., Pagan K.E., Taylor M.S.,Currie P.D., Jackson I.J.; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 14694081 3 Klovins J., Haitina T., Fridmanis D., Kapa I., Fredriksson R.,Schioth H.B.; "Genomic structure and pharmacological properties of melanocortinreceptor genes in Takifugu rubripes."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 445998 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20539 |
Swiss-prot Accession number | Q7ZSY9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 300 Amino acids |
Molecular weight | 34167 |
Domain Name | 7tm_1 |
References | 1 Logan D.W., Bryson-Richardson R.J., Pagan K.E., Taylor M.S.,Currie P.D., Jackson I.J.; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 14694081 |
Hormone | N/A |
Gene ID | 100187712 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20540 |
Swiss-prot Accession number | Q7ZT40 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 340 Amino acids |
Molecular weight | 38366 |
Domain Name | 7tm_1 |
References | 1 Logan D.W., Bryson-Richardson R.J., Pagan K.E., Taylor M.S.,Currie P.D., Jackson I.J.; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 14694081 3 Klovins J., Haitina T., Fridmanis D., Kapa I., Fredriksson R.,Schioth H.B.; "Genomic structure and pharmacological properties of melanocortinreceptor genes in Takifugu rubripes."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 445999 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20541 |
Swiss-prot Accession number | Q7ZTA1 (Sequence in FASTA format) |
Description | Melanocortin 3 receptor. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 327 Amino acids |
Molecular weight | 35937 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12620396 |
Hormone | N/A |
Gene ID | 353153 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20542 |
Swiss-prot Accession number | Q7ZTA2 (Sequence in FASTA format) |
Description | Melanocortin 2 receptor. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 304 Amino acids |
Molecular weight | 34082 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12620396 |
Hormone | N/A |
Gene ID | 353152 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20543 |
Swiss-prot Accession number | Q7ZTA3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 323 Amino acids |
Molecular weight | 36633 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12620396 2 Humphries M.; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 353151 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20544 |
Swiss-prot Accession number | Q802F8 (Sequence in FASTA format) |
Description | Melanocortin 1-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35271 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12873211 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20545 |
Swiss-prot Accession number | Q802F9 (Sequence in FASTA format) |
Description | Melanocortin 1-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35408 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12873211 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20546 |
Swiss-prot Accession number | Q802G0 (Sequence in FASTA format) |
Description | Melanocortin 1-receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35342 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12873211 2 Wada A., Tsudzuki M.; "Nucleotide polymorphisms at the Mc1r locus of poultry."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20547 |
Swiss-prot Accession number | Q80SU9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35403 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 2 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20548 |
Swiss-prot Accession number | Q80SV0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35433 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20549 |
Swiss-prot Accession number | Q80SV5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35444 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20550 |
Swiss-prot Accession number | Q80SV7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35444 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20551 |
Swiss-prot Accession number | Q80SW2 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35460 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20552 |
Swiss-prot Accession number | Q80SX1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35435 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20553 |
Swiss-prot Accession number | Q80SZ1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35252 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20554 |
Swiss-prot Accession number | Q80SZ3 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35435 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 2 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20555 |
Swiss-prot Accession number | Q80T00 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35419 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 2 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20556 |
Swiss-prot Accession number | Q80WA1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35437 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20557 |
Swiss-prot Accession number | Q80WA2 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35433 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20558 |
Swiss-prot Accession number | Q80XY4 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35232 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20559 |
Swiss-prot Accession number | Q80XY5 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35304 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20560 |
Swiss-prot Accession number | Q80XY6 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35416 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20561 |
Swiss-prot Accession number | Q80XY7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35456 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20562 |
Swiss-prot Accession number | Q80XY8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35387 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20563 |
Swiss-prot Accession number | Q80XY9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35416 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20564 |
Swiss-prot Accession number | Q80XZ0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Chaetodipus intermedius (Rock pocket mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 35383 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12694282 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20565 |
Swiss-prot Accession number | Q864G8 (Sequence in FASTA format) |
Description | Melanocortin-1 receptor. |
Source organism | Aotus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Aotidae; Aotus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34654 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20566 |
Swiss-prot Accession number | Q86YW1 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor variant L93R. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34749 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12473109 2 Sanchez Mas J.M., Olivares C., Lozano J.A., Garcia-Borron J.C.,Jimenez-Cervantes C.; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20567 |
Swiss-prot Accession number | Q8JGW1 (Sequence in FASTA format) |
Description | Melanocortin 5b receptor (Melanocortin 5a receptor). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 328 Amino acids |
Molecular weight | 37008 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12091460 2 PubMed abstract 12620396 |
Hormone | N/A |
Gene ID | 286835 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20568 |
Swiss-prot Accession number | Q8JGW2 (Sequence in FASTA format) |
Description | Melanocortin 5a receptor (Melanocortin 5b receptor). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 316 Amino acids |
Molecular weight | 35836 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12091460 2 Logan D.W., Bryson-Richardson R.J., Pagan K.E., Taylor M.S.,Currie P.D., Jackson I.J.; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 286834 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20569 |
Swiss-prot Accession number | Q8JGW3 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 326 Amino acids |
Molecular weight | 36421 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12091460 2 PubMed abstract 12620396 |
Hormone | N/A |
Gene ID | 286833 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20570 |
Swiss-prot Accession number | Q8WMC6 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 317 Amino acids |
Molecular weight | 34913 |
Domain Name | 7tm_1 |
References | 1 Rouzaud F., Guibert S., Julien R., Oulmouden A.; "Transcriptional regulation of bovine mRNA encoding melanocortin 1receptor (MC1R)."; Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
2 Rouzaud F., Guibert S., Julien R., Oulmouden A.; "Cloning and characterization of bovine extension gene."; Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 281298 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20571 |
Swiss-prot Accession number | Q90VV8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35009 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20572 |
Swiss-prot Accession number | Q90VX9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35025 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20573 |
Swiss-prot Accession number | Q90VY0 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor (Melanocortin receptor-4). |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 322 Amino acids |
Molecular weight | 35975 |
Domain Name | 7tm_1 |
References | 1 Logan D.W., Bryson-Richardson R.J., Pagan K.E., Taylor M.S.,Currie P.D., Jackson I.J.; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 14694081 3 Kunimoto M., Mizukami Y.; "Discrimination of Takifugu species based on melanocortin receptor-1gene nucleotide sequence."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 445900 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20574 |
Swiss-prot Accession number | Q90VY8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35038 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20575 |
Swiss-prot Accession number | Q90W02 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35066 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20576 |
Swiss-prot Accession number | Q90Y72 (Sequence in FASTA format) |
Description | Melanocortin receptor-4. |
Source organism | Takifugu poecilonotus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 322 Amino acids |
Molecular weight | 35945 |
Domain Name | 7tm_1 |
References | 1 Kunimoto M., Mizukami Y.; "Discrimination of Takifugu species based on melanocortin receptor-1gene nucleotide sequence."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20577 |
Swiss-prot Accession number | Q90Y73 (Sequence in FASTA format) |
Description | Melanocortin receptor-4. |
Source organism | Takifugu porphyreus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 322 Amino acids |
Molecular weight | 35948 |
Domain Name | 7tm_1 |
References | 1 Kunimoto M., Mizukami Y.; "Discrimination of Takifugu species based on melanocortin receptor-1gene nucleotide sequence."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20578 |
Swiss-prot Accession number | Q90Y74 (Sequence in FASTA format) |
Description | Melanocortin receptor-4. |
Source organism | Takifugu radiatus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 322 Amino acids |
Molecular weight | 35918 |
Domain Name | 7tm_1 |
References | 1 Kunimoto M., Mizukami Y.; "Discrimination of Takifugu species based on melanocortin receptor-1gene nucleotide sequence."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20579 |
Swiss-prot Accession number | Q90ZP7 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Tangara cucullata |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Tangara. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35016 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20580 |
Swiss-prot Accession number | Q90ZP8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35064 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20581 |
Swiss-prot Accession number | Q90ZP9 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 35039 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20582 |
Swiss-prot Accession number | Q90ZQ0 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Coereba flaveola (bannaquit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Fringillidae; Emberizinae;Thraupini; Coereba. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 314 Amino acids |
Molecular weight | 34999 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11369199 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20583 |
Swiss-prot Accession number | Q95MM8 (Sequence in FASTA format) |
Description | Melanocortin 1 receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 320 Amino acids |
Molecular weight | 34592 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11404341 2 Kijas J.W., Moller M., Andersson L.; Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases. 3 Shi K., Wang A., Li N.; "Single nucleotide polymorphisms (SNPs) analysis on the extension(MC1R), the white (KIT) and the agouti (ASIP) loci and theirassociation with coat color phenotypes of pigs."; Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. 4 Shi K., Wang A., Li N., Deng X.M.; "Single Nucleotide Polymorphism Analysis on Melanocortin Receptor 1(MC1R) of Chinese Native Pig."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 5 Cho I., Jung J., Jung Y., Jeon J.; "The complete sequence of Pig (Sus scrofa) MC1R gene."; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 494018 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20584 |
Swiss-prot Accession number | Q4FE80 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 354 Amino acids |
Molecular weight | 39760 |
Domain Name | 7tm_1 |
References | 1 Romero A.P., Kausel G., Muller M., Figueroa J.; "Identification of novel prolactin releasing peptide receptors ofCyprinus carpio and Salmo salar expressed in the pituitary gland."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20585 |
Swiss-prot Accession number | Q4FE81 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 370 Amino acids |
Molecular weight | 41790 |
Domain Name | 7tm_1 |
References | 1 Romero A.P., Kausel G., Muller M., Figueroa J.; "Identification of novel prolactin releasing peptide receptors ofCyprinus carpio and Salmo salar expressed in the pituitary gland."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 654782 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20586 |
Swiss-prot Accession number | Q4FE82 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor. |
Source organism | Salmo salar (Atlantic salmon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Salmo. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 362 Amino acids |
Molecular weight | 40526 |
Domain Name | 7tm_1 |
References | 1 Romero A.P., Kausel G., Muller M., Figueroa J.; "Identification of novel prolactin releasing peptide receptors ofCyprinus carpio and Salmo salar expressed in the pituitary gland."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100136462 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20587 |
Swiss-prot Accession number | Q4VVG4 (Sequence in FASTA format) |
Description | Prolactin releasing peptide receptor-like protein. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 352 Amino acids |
Molecular weight | 39808 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15885496 |
Hormone | N/A |
Gene ID | 428834 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20588 |
Swiss-prot Accession number | Q5MAG4 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 352 Amino acids |
Molecular weight | 40640 |
Domain Name | 7tm_1 |
References | 1 Wang Y., Wang Y.J., Hon C.C., Li K.B., Leung F.C.; "Gallus gallus prolactin-releasing peptide receptor (PrRPR) mRNA."; Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 428985 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20589 |
Swiss-prot Accession number | Q3UVV5 (Sequence in FASTA format) |
Description | Adult male diencephalon cDNA, RIKEN full-length enriched library,clone:9330174K12 product:somatostatin receptor 3, full insertsequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 428 Amino acids |
Molecular weight | 47216 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 20607 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20590 |
Swiss-prot Accession number | Q3UZM7 (Sequence in FASTA format) |
Description | 8 days embryo whole body cDNA, RIKEN full-length enriched library,clone:5730410G03 product:Somatostatin subtype 5 receptor homolog(Adult male pituitary gland cDNA, RIKEN full-length enriched library,clone:5330415B05 product:Somatostatin subtype 5 receptor homolog). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 362 Amino acids |
Molecular weight | 40008 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 20609 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20591 |
Swiss-prot Accession number | Q4L144 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 3. |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 425 Amino acids |
Molecular weight | 45961 |
Domain Name | 7tm_1 |
References | 1 Liew C.W., Richter D., Kreienkamp H.-J.; "Interaction of human SSTR3 receptor with tight junction protein,MUPP1, via PDZ domain."; Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 481272 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20592 |
Swiss-prot Accession number | Q541E0 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 5. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 364 Amino acids |
Molecular weight | 39202 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12072395 |
Hormone | N/A |
Gene ID | 6755 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20593 |
Swiss-prot Accession number | Q543T0 (Sequence in FASTA format) |
Description | Adult male corpora quadrigemina cDNA, RIKEN full-length enrichedlibrary, clone:B230396D21 product:SOMATOSTATIN RECEPTOR TYPE 1, fullinsert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 391 Amino acids |
Molecular weight | 42718 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 20605 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20594 |
Swiss-prot Accession number | Q6PQM1 (Sequence in FASTA format) |
Description | Type 3 somatostatin receptor. |
Source organism | Haplochromis burtoni (Burton's mouthbrooder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini;Astatotilapia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 483 Amino acids |
Molecular weight | 53534 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 17374406 2 PubMed abstract 16887916 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20595 |
Swiss-prot Accession number | Q6PQM2 (Sequence in FASTA format) |
Description | Type 2 somatostatin receptor. |
Source organism | Haplochromis burtoni (Burton's mouthbrooder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini;Astatotilapia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 370 Amino acids |
Molecular weight | 41832 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 17374406 2 PubMed abstract 16887916 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20596 |
Swiss-prot Accession number | Q8BQ97 (Sequence in FASTA format) |
Description | 12 days embryo spinal ganglion cDNA, RIKEN full-length enrichedlibrary, clone:D130013H04 product:somatostatin receptor 4, full insertsequence (Somatostatin receptor 4) (Sstr4). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 385 Amino acids |
Molecular weight | 42046 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 9 Leongamornlert D.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. 10 Farber C.R., Corva P.M., Medrano J.F.; "Characterization of quantitative trait loci influencing growth andadiposity using congenic mouse strains."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 20608 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20597 |
Swiss-prot Accession number | Q8UWL5 (Sequence in FASTA format) |
Description | Somatostatin receptor 2. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 370 Amino acids |
Molecular weight | 41365 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11707075 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20598 |
Swiss-prot Accession number | Q9JK40 (Sequence in FASTA format) |
Description | Somatostatin subtype 5 receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 385 Amino acids |
Molecular weight | 42489 |
Domain Name | 7tm_1 |
References | 1 O'Carroll A.-M.; "Cloning, sequence and tissue distribution of the gene encoding amouse somatostatin subtype 5 receptor."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20599 |
Swiss-prot Accession number | O15218 (Sequence in FASTA format) |
Description | Adrenomedullin receptor (AM-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Highly expressed in heart, skeletal muscle, immune system, adrenal gland and liver. |
Post translational modification | N/A |
Function | Receptor for adrenomedullin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 404 Amino acids |
Molecular weight | 45323 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9367907 2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 15489334 |
Hormone | N/A |
Gene ID | 11318 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20600 |
Swiss-prot Accession number | P43142 (Sequence in FASTA format) |
Description | Adrenomedullin receptor (AM-R) (G10D) (NOW). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in liver and lung. |
Post translational modification | N/A |
Function | Receptor for adrenomedullin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 395 Amino acids |
Molecular weight | 45497 |
Domain Name | 7tm_1 |
References | 1 Saeki Y., Ueno S., Nagai Y., Yanagihara T.; Submitted (JUN-1993) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 8288218 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20601 |
Swiss-prot Accession number | P31392 (Sequence in FASTA format) |
Description | Adrenomedullin receptor (AM-R) (G10D) (NOW). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in a wide variety of peripheral tissues in the adult rat with prominent expression in lung, testis, adrenal, and liver. |
Post translational modification | N/A |
Function | Receptor for adrenomedullin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 395 Amino acids |
Molecular weight | 45196 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8382168 2 Harrison J.K.; Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 8390839 4 PubMed abstract 7592696 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20602 |
Swiss-prot Accession number | Q2UV90 (Sequence in FASTA format) |
Description | Putative melanin concentrating hormone receptor 2. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 339 Amino acids |
Molecular weight | 38691 |
Domain Name | 7tm_1 |
References | 1 Larsson N., Hermansson N.O., Dellsen A., Ulvsbaeck M., Schneckener S.; "Cloning of the pig Melanin concentrating hormone receptor 2(pigMCH2)."; Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 733682 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20603 |
Swiss-prot Accession number | Q5QPY1 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 353 Amino acids |
Molecular weight | 38949 |
Domain Name | 7tm_1 |
References | 1 Prestle J., Adomeit A., Hammer E., Ziehar T., Missler B., Appl T.,Schindler M.; "Cloning and functional characterization of porcine melanin-concentrating hormone receptor 1 (MCH1-R)."; Diabetologia 47:A191-A191(2004).
|
Hormone | N/A |
Gene ID | 397295 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20606 |
Swiss-prot Accession number | O77152 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 443 Amino acids |
Molecular weight | 50177 |
Domain Name | 7tm_1 |
References | 1 Hauser F., Sondergaard L., Grimmelikhuijzen C.J.P.; "Molecular cloning, genomic organization and developmental regulationof a novel receptor from Drosophila melanogaster structurally relatedto gonadotropin-releasing hormone receptors from vertebrates."; Biochem. Biophys. Res. Commun. 49:822-828(1998).
2 PubMed abstract 9731220 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20607 |
Swiss-prot Accession number | Q2V2K5 (Sequence in FASTA format) |
Description | GnRH receptor. |
Source organism | Octopus vulgaris (Octopus) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Cephalopoda; Coleoidea; Neocoleoidea;Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 407 Amino acids |
Molecular weight | 46003 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16367741 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20608 |
Swiss-prot Accession number | Q2V618 (Sequence in FASTA format) |
Description | Gonadotrophin-releasing hormone receptor 2A. |
Source organism | Micropogonias undulatus (Atlantic croaker) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Sciaenidae; Micropogonias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 423 Amino acids |
Molecular weight | 47692 |
Domain Name | 7tm_1 |
References | 1 Mohamed J.S., Khan I.A.; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20609 |
Swiss-prot Accession number | Q3LG30 (Sequence in FASTA format) |
Description | Type 2/nmI-2 gonadotropin-releasing hormone receptor splice variant. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 365 Amino acids |
Molecular weight | 41611 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16122867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20610 |
Swiss-prot Accession number | Q3LG31 (Sequence in FASTA format) |
Description | Type 2/nmI-2 gonadotropin-releasing hormone receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 354 Amino acids |
Molecular weight | 40274 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16122867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20611 |
Swiss-prot Accession number | Q3LG33 (Sequence in FASTA format) |
Description | Type 2/nmI-1 gonadotropin-releasing hormone receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 366 Amino acids |
Molecular weight | 41076 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16122867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20612 |
Swiss-prot Accession number | Q3LG36 (Sequence in FASTA format) |
Description | Type 1/III-3 gonadotropin-releasing hormone receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 393 Amino acids |
Molecular weight | 44325 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16122867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20613 |
Swiss-prot Accession number | Q3LG37 (Sequence in FASTA format) |
Description | Type 1/III-2 gonadotropin-releasing hormone receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 417 Amino acids |
Molecular weight | 46406 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16122867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20614 |
Swiss-prot Accession number | Q3LG39 (Sequence in FASTA format) |
Description | Type 1/III-1 gonadotropin-releasing hormone receptor. |
Source organism | Tetraodon nigroviridis (Green puffer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Tetraodon. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 331 Amino acids |
Molecular weight | 37635 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16122867 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20615 |
Swiss-prot Accession number | Q3ZK34 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 3. |
Source organism | Ciona intestinalis (Transparent sea squirt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Urochordata; Ascidiacea; Enterogona;Phlebobranchia; Cionidae; Ciona. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 454 Amino acids |
Molecular weight | 52235 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15961566 |
Hormone | N/A |
Gene ID | 619219 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20616 |
Swiss-prot Accession number | Q3ZK35 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 2. |
Source organism | Ciona intestinalis (Transparent sea squirt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Urochordata; Ascidiacea; Enterogona;Phlebobranchia; Cionidae; Ciona. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 401 Amino acids |
Molecular weight | 45408 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15961566 |
Hormone | N/A |
Gene ID | 619220 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20617 |
Swiss-prot Accession number | Q3ZK36 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 1. |
Source organism | Ciona intestinalis (Transparent sea squirt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Urochordata; Ascidiacea; Enterogona;Phlebobranchia; Cionidae; Ciona. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 450 Amino acids |
Molecular weight | 50807 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15961566 |
Hormone | N/A |
Gene ID | 619221 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20618 |
Swiss-prot Accession number | Q4ZGM0 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Paralichthys olivaceus (Japanese flounder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Pleuronectiformes;Pleuronectoidei; Paralichthyidae; Paralichthys. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 415 Amino acids |
Molecular weight | 47029 |
Domain Name | 7tm_1 |
References | 1 Fang B.H., Sun X.Q.; "Cloning and characterization of GnRH-R gene from Japanese flounder,Paralichthys olivaceus."; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20619 |
Swiss-prot Accession number | Q5PY26 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor I. |
Source organism | Acanthopagrus schlegeli (Black porgy) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Sparidae; Acanthopagrus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 426 Amino acids |
Molecular weight | 48252 |
Domain Name | 7tm_1 |
References | 1 Lin C.-J., Chang C.-F.; "Cloning of black porgy gonadotropin releasing hormone receptor-I(GnRHR-I)."; Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20620 |
Swiss-prot Accession number | Q5U7L3 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 328 Amino acids |
Molecular weight | 38045 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 17095587 |
Hormone | N/A |
Gene ID | 100009509 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20621 |
Swiss-prot Accession number | Q6QGW2 (Sequence in FASTA format) |
Description | GnRH II receptor 7 transmembrane. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 377 Amino acids |
Molecular weight | 41498 |
Domain Name | 7tm_1 |
References | 1 Neill J.D., Musgrove L.C., Duck L.W.; "The New GnRH Receptors: Function and Relative Role."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 414423 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20622 |
Swiss-prot Accession number | Q6U104 (Sequence in FASTA format) |
Description | GnRH receptor type 3. |
Source organism | Oreochromis aureus x Oreochromis niloticus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 421 Amino acids |
Molecular weight | 47552 |
Domain Name | 7tm_1 |
References | 1 Levavi-Sivan B., Avitan A.; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20623 |
Swiss-prot Accession number | Q6U105 (Sequence in FASTA format) |
Description | GnRH receptor type 1. |
Source organism | Oreochromis aureus x Oreochromis niloticus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 390 Amino acids |
Molecular weight | 44407 |
Domain Name | 7tm_1 |
References | 1 Levavi-Sivan B., Avitan A.; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20624 |
Swiss-prot Accession number | Q6UJG5 (Sequence in FASTA format) |
Description | Corazonin receptor. |
Source organism | Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Sphingoidea;Sphingidae; Sphinginae; Manduca. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 435 Amino acids |
Molecular weight | 49566 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15096620 2 Kim Y.-J., Adams M.E.; Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20625 |
Swiss-prot Accession number | Q6WGL8 (Sequence in FASTA format) |
Description | Adipokinetic hormone receptor. |
Source organism | Periplaneta americana (American cockroach) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Orthopteroidea; Dictyoptera; Blattaria; Blattidae;Blattinae; Periplaneta. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 456 Amino acids |
Molecular weight | 51803 |
Domain Name | 7tm_1 |
References | 1 Derst C., Wicher D.; "Cloning and sequencing of a Periplaneta americana adipokinetichormone receptor."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20627 |
Swiss-prot Accession number | Q76BI3 (Sequence in FASTA format) |
Description | GnRH receptor type2. |
Source organism | Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 42397 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15677717 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20628 |
Swiss-prot Accession number | Q76BI4 (Sequence in FASTA format) |
Description | GnRH receptor type1. |
Source organism | Oreochromis niloticus (Nile tilapia) (Tilapia nilotica) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Tilapiini;Oreochromis. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 375 Amino acids |
Molecular weight | 42283 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15677717 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20629 |
Swiss-prot Accession number | Q76D34 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 2. |
Source organism | Eublepharis macularius (Leopard gecko) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Lepidosauria; Squamata; Scleroglossa; Gekkota; Eublepharidae;Eublepharus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 373 Amino acids |
Molecular weight | 42224 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15062552 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20630 |
Swiss-prot Accession number | Q7ZZP0 (Sequence in FASTA format) |
Description | GnRH receptor 3. |
Source organism | Rana ridibunda (Laughing frog) (Marsh frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 424 Amino acids |
Molecular weight | 47802 |
Domain Name | 7tm_1 |
References | 1 Li J.H., Seong J.Y., Kwon H.B.; "Rana ridibunda GnRH receptor 3."; Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20631 |
Swiss-prot Accession number | Q7ZZP1 (Sequence in FASTA format) |
Description | GnRH receptor 2. |
Source organism | Rana ridibunda (Laughing frog) (Marsh frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 42185 |
Domain Name | 7tm_1 |
References | 1 Li J.H., Seong J.Y., Kwon H.B.; "Rana ridibunda GnRH receptor 2."; Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20632 |
Swiss-prot Accession number | Q7ZZP2 (Sequence in FASTA format) |
Description | GnRH receptor 1. |
Source organism | Rana ridibunda (Laughing frog) (Marsh frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 407 Amino acids |
Molecular weight | 46071 |
Domain Name | 7tm_1 |
References | 1 Li J.H., Seong J.Y., Kwon H.B.; "Rana ridibunda GnRH receptor 1."; Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20633 |
Swiss-prot Accession number | Q869J2 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Ciona intestinalis (Transparent sea squirt) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Urochordata; Ascidiacea; Enterogona;Phlebobranchia; Cionidae; Ciona. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 450 Amino acids |
Molecular weight | 50902 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14644499 |
Hormone | N/A |
Gene ID | 445790 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20634 |
Swiss-prot Accession number | Q8ITC8 (Sequence in FASTA format) |
Description | Putative corazonin receptor. |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 579 Amino acids |
Molecular weight | 64083 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12177421 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20635 |
Swiss-prot Accession number | Q8MX81 (Sequence in FASTA format) |
Description | Drm corazonin receptor. |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 579 Amino acids |
Molecular weight | 64187 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12379215 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20636 |
Swiss-prot Accession number | Q8T6U9 (Sequence in FASTA format) |
Description | AKH receptor. |
Source organism | Bombyx mori (Silk moth) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;Bombycidae; Bombyx. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 405 Amino acids |
Molecular weight | 46200 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11904407 |
Hormone | N/A |
Gene ID | 692603 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20637 |
Swiss-prot Accession number | Q90WJ2 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor type II. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 418 Amino acids |
Molecular weight | 47378 |
Domain Name | 7tm_1 |
References | 1 Troskie B.E., Illing N., Findlayson K., Lowe S., Katz A.A.,Millar R.P.; "Molecular cloning of a novel (type II) gonadotropin-releasing hormonereceptor from Xenopus laevis sympathetic ganglia."; Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 373823 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20638 |
Swiss-prot Accession number | Q9DGQ9 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Anguilla japonica (Japanese eel) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Anguilliformes; Anguillidae;Anguilla. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 380 Amino acids |
Molecular weight | 43138 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10936038 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20639 |
Swiss-prot Accession number | Q9PT72 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Seriola dumerili (Mediterranean greater amberjack) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Carangoidei;Carangidae; Seriola. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 426 Amino acids |
Molecular weight | 47853 |
Domain Name | 7tm_1 |
References | 1 Bogerd J., Blomenrohr M., Schulz R.W., Goos H.J.; "Cloning and functional characterization of the cDNA encoding theGnRH-R of Seriola dumerilii."; Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20640 |
Swiss-prot Accession number | Q9PW33 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Typhlonectes natans (Rubber eel) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Gymnophiona; Typhlonectidae; Typhlonectes. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 410 Amino acids |
Molecular weight | 46422 |
Domain Name | 7tm_1 |
References | 1 Ebersole T.J., Goetz F.W., Boyd S.K.; "Cloning of the gonadotropin-releasing hormone receptor (GnRH-R) fromthe amphibian, Typhlonectes natans."; Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20641 |
Swiss-prot Accession number | Q9VM96 (Sequence in FASTA format) |
Description | CG11325-PA, isoform A (CG11325-PB, isoform B). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 443 Amino acids |
Molecular weight | 50191 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10731132 2 PubMed abstract 16110336 3 PubMed abstract 12537568 4 PubMed abstract 12537572 5 PubMed abstract 12537573 6 Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. 7 Smith C.D., Shu S., Yandell M.D., Karpen G.H.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8 Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9 Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10 Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 33942 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20642 |
Swiss-prot Accession number | Q9VTW7 (Sequence in FASTA format) |
Description | CG10698-PA (RE49422p). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 579 Amino acids |
Molecular weight | 64115 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10731132 2 PubMed abstract 16110336 3 PubMed abstract 12537568 4 PubMed abstract 12537572 5 PubMed abstract 12537573 6 Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. 7 Smith C.D., Shu S., Yandell M.D., Karpen G.H.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8 Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9 Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10 Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 11 Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J.,Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E.,George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G.,Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S.,Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M.,Celniker S.; Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 39409 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20643 |
Swiss-prot Accession number | O43193 (Sequence in FASTA format) |
Description | Motilin receptor (G-protein coupled receptor 38). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed only in thyroid, stomach, and bone marrow. |
Post translational modification | N/A |
Function | Receptor for motilin. |
Protein Length | 412 Amino acids |
Molecular weight | 45344 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9441746 2 PubMed abstract 10381885 3 King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15057823 5 PubMed abstract 11322507 |
Hormone | N/A |
Gene ID | 2862 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20644 |
Swiss-prot Accession number | O88820 (Sequence in FASTA format) |
Description | G protein-coupled receptor. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 352 Amino acids |
Molecular weight | 39000 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9735333 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20645 |
Swiss-prot Accession number | O93412 (Sequence in FASTA format) |
Description | Orphan G protein-coupled receptor. |
Source organism | Sphoeroides nephelus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Sphoeroides. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 374 Amino acids |
Molecular weight | 42325 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628755 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20646 |
Swiss-prot Accession number | O93413 (Sequence in FASTA format) |
Description | Orphan G protein-coupled receptor. |
Source organism | Sphoeroides nephelus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Sphoeroides. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 363 Amino acids |
Molecular weight | 41325 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628755 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20647 |
Swiss-prot Accession number | O93414 (Sequence in FASTA format) |
Description | Orphan G protein-coupled receptor. |
Source organism | Sphoeroides nephelus |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Sphoeroides. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 559 Amino acids |
Molecular weight | 61957 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628755 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20648 |
Swiss-prot Accession number | Q3UYL6 (Sequence in FASTA format) |
Description | Adult male medulla oblongata cDNA, RIKEN full-length enriched library,clone:6330439E06 product:thyrotropin releasing hormone receptor, fullinsert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 393 Amino acids |
Molecular weight | 44587 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20649 |
Swiss-prot Accession number | Q6ISR8 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 289 Amino acids |
Molecular weight | 32153 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 2693 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20650 |
Swiss-prot Accession number | Q6YGZ3 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor 1a. |
Source organism | Acanthopagrus schlegeli (Black porgy) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Sparidae; Acanthopagrus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 385 Amino acids |
Molecular weight | 43697 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15062547 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20651 |
Swiss-prot Accession number | Q7ZT14 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor (Growth hormone secretagoguereceptor type 1a). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 347 Amino acids |
Molecular weight | 39439 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14511992 |
Hormone | N/A |
Gene ID | 378911 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20652 |
Swiss-prot Accession number | Q86C62 (Sequence in FASTA format) |
Description | Putative ETH receptor splicing variant b (CG5911-PB, isoform B). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 461 Amino acids |
Molecular weight | 50672 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12586820 2 PubMed abstract 10731132 3 PubMed abstract 16110336 4 PubMed abstract 12537568 5 PubMed abstract 12537572 6 PubMed abstract 12537573 7 PubMed abstract 12537574 8 Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9 Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10 FlyBase; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 11 Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 42523 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20653 |
Swiss-prot Accession number | Q9DFA9 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 2. |
Source organism | Catostomus commersoni (White sucker) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Catostomidae; Catostomus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 513 Amino acids |
Molecular weight | 57351 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11703088 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20654 |
Swiss-prot Accession number | Q9DFB0 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 1. |
Source organism | Catostomus commersoni (White sucker) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Catostomidae; Catostomus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 404 Amino acids |
Molecular weight | 45526 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11703088 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20655 |
Swiss-prot Accession number | Q9QWW3 (Sequence in FASTA format) |
Description | Thyrotropin releasing hormone receptor-2. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 352 Amino acids |
Molecular weight | 39048 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9822707 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20656 |
Swiss-prot Accession number | Q9VDC4 (Sequence in FASTA format) |
Description | CG5911-PA, isoform A (Putative ETH receptor splicing variant a). |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 471 Amino acids |
Molecular weight | 52774 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10731132 2 PubMed abstract 16110336 3 PubMed abstract 12537568 4 PubMed abstract 12537572 5 PubMed abstract 12537573 6 PubMed abstract 12537574 7 Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R.,Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E.,Yu C., Rubin G.; "Drosophila melanogaster release 4 sequence."; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 8 Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S.,Svirskas R., Rubin G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 9 FlyBase; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 10 Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R.,Park S., Svirskas R., Karpen G.; Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. 11 PubMed abstract 12586820 |
Hormone | N/A |
Gene ID | 42523 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20657 |
Swiss-prot Accession number | P49285 (Sequence in FASTA format) |
Description | Melatonin receptor type 1A (MEL-1A-R) (CKA). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in optic tectum and retina, less in neostriatum, hypothalamus and thalamus. |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). |
Protein Length | 353 Amino acids |
Molecular weight | 39896 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7576645 |
Hormone | N/A |
Gene ID | 396319 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20658 |
Swiss-prot Accession number | P48039 (Sequence in FASTA format) |
Description | Melatonin receptor type 1A (Mel-1A-R) (Mel1a melatonin receptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus. |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Protein Length | 350 Amino acids |
Molecular weight | 39375 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7946354 2 PubMed abstract 10471411 3 PubMed abstract 15489334 |
Hormone | Detail in HMRbase |
Gene ID | 4543 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20659 |
Swiss-prot Accession number | Q61184 (Sequence in FASTA format) |
Description | Melatonin receptor type 1A (Mel-1A-R) (Mel1a melatonin receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 353 Amino acids |
Molecular weight | 39837 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8754776 |
Hormone | N/A |
Gene ID | 17773 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20660 |
Swiss-prot Accession number | P49217 (Sequence in FASTA format) |
Description | Melatonin receptor type 1A (Mel-1A-R) (Mel1a melatonin receptor). |
Source organism | Phodopus sungorus (Striped hairy-footed hamster) (Djungarian hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Phodopus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | At least in the brain, more precisely in the pars tuberalis and the suprachiasmatic nucleus. |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Protein Length | 353 Amino acids |
Molecular weight | 39685 |
Domain Name | 7tm_1 |
References | 1 Weaver D.R., Liu C., Reppert S.M.; Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 7946354 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20661 |
Swiss-prot Accession number | P48040 (Sequence in FASTA format) |
Description | Melatonin receptor type 1A (Mel-1A-R) (Mel1a melatonin receptor). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Protein Length | 366 Amino acids |
Molecular weight | 40401 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7946354 2 PubMed abstract 9194573 |
Hormone | N/A |
Gene ID | 443022 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20662 |
Swiss-prot Accession number | P49286 (Sequence in FASTA format) |
Description | Melatonin receptor type 1B (Mel-1B-R) (Mel1b melatonin receptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in retina and less in brain and hippocampus. |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Protein Length | 362 Amino acids |
Molecular weight | 40188 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7568007 2 PubMed abstract 10696804 3 King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15489334 |
Hormone | N/A |
Gene ID | 4544 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20663 |
Swiss-prot Accession number | Q8CIQ6 (Sequence in FASTA format) |
Description | Melatonin receptor type 1B (Mel-1B-R) (Mel1b melatonin receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). |
Protein Length | 364 Amino acids |
Molecular weight | 40261 |
Domain Name | 7tm_1 |
References | 1 Jin X., von Gall C., Pieschl R.L., Gribkoff V.K., Stehle J.H.,Reppert S.M., Weaver D.R.; "Targeted disruption of the mouse Mel1b melatonin receptor."; Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
2 Resuehr D., Olcese J.; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12679517 |
Hormone | N/A |
Gene ID | 244701 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20664 |
Swiss-prot Accession number | P49288 (Sequence in FASTA format) |
Description | Melatonin receptor type 1C (MEL-1C-R) (CKB). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in optic tectum, neostriatum, hypothalamus, thalamus and pineal gland, less in cerebellum and retina. |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). |
Protein Length | 346 Amino acids |
Molecular weight | 38576 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7576645 |
Hormone | N/A |
Gene ID | 396318 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20665 |
Swiss-prot Accession number | P49219 (Sequence in FASTA format) |
Description | Melatonin receptor type 1C (MEL-1C-R). |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | High affinity receptor for melatonin. Likely to mediate the potent effects of melatonin on pigment aggregation in melanophores. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. |
Protein Length | 420 Amino acids |
Molecular weight | 47425 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7517042 |
Hormone | N/A |
Gene ID | 397808 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20666 |
Swiss-prot Accession number | Q13585 (Sequence in FASTA format) |
Description | Melatonin-related receptor (G protein-coupled receptor 50) (H9). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Hypothalamus and pituitary. |
Post translational modification | N/A |
Function | Does not bind melatonin. |
Protein Length | 613 Amino acids |
Molecular weight | 66924 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8647286 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20667 |
Swiss-prot Accession number | O88495 (Sequence in FASTA format) |
Description | Melatonin-related receptor (G protein-coupled receptor 50) (H9). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Does not bind melatonin. |
Protein Length | 583 Amino acids |
Molecular weight | 64301 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9933574 |
Hormone | N/A |
Gene ID | 14765 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20668 |
Swiss-prot Accession number | Q28558 (Sequence in FASTA format) |
Description | Melatonin-related receptor (G protein-coupled receptor 50) (H9). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Does not bind melatonin (By similarity). |
Protein Length | 575 Amino acids |
Molecular weight | 62810 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9744482 2 PubMed abstract 8647286 |
Hormone | N/A |
Gene ID | 443023 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20669 |
Swiss-prot Accession number | P87496 (Sequence in FASTA format) |
Description | Mel-1c(B) melatonin receptor. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 354 Amino acids |
Molecular weight | 39931 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9212055 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20670 |
Swiss-prot Accession number | P87499 (Sequence in FASTA format) |
Description | Mel-1c(A) melatonin receptor. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 354 Amino acids |
Molecular weight | 39881 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9212055 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20671 |
Swiss-prot Accession number | Q3LTL8 (Sequence in FASTA format) |
Description | Mel-1b melatonin receptor. |
Source organism | Poephila guttata (Zebra finch) (Taeniopygia guttata) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Passeriformes; Passeroidea; Estrildidae; Estrildinae;Taeniopygia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 361 Amino acids |
Molecular weight | 40581 |
Domain Name | 7tm_1 |
References | 1 Metzdorf R.; "Melatonin receptor expression in the forebrain of a songbird."; Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 751588 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20672 |
Swiss-prot Accession number | Q3SXF8 (Sequence in FASTA format) |
Description | Melatonin receptor 1B. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 364 Amino acids |
Molecular weight | 40289 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20673 |
Swiss-prot Accession number | Q567Z2 (Sequence in FASTA format) |
Description | Melatonin receptor 1A. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 350 Amino acids |
Molecular weight | 39644 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20674 |
Swiss-prot Accession number | Q5RGH4 (Sequence in FASTA format) |
Description | Melatonin receptor 1B. |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 347 Amino acids |
Molecular weight | 38979 |
Domain Name | 7tm_1 |
References | 1 Kerry G.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
2 Dunn M.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20675 |
Swiss-prot Accession number | Q9DG47 (Sequence in FASTA format) |
Description | P2.6 melatonin receptor Mel-1B. |
Source organism | Esox lucius (Northern pike) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Esociformes;Esocidae; Esox. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 367 Amino acids |
Molecular weight | 41649 |
Domain Name | 7tm_1 |
References | 1 Gaildrat P., Falcon J.; "Molecular and functional characterization of a melatonin receptorexpressed in pike brain."; Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20676 |
Swiss-prot Accession number | Q9PT20 (Sequence in FASTA format) |
Description | Melatonin receptor Mel1a. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 383 Amino acids |
Molecular weight | 43266 |
Domain Name | 7tm_1 |
References | 1 Mazurais D., Brierley I., Kah O., Williams L.; "Expression of rainbow trout melatonin Receptor."; Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100135888 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20744 |
Swiss-prot Accession number | P18130 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. |
Protein Length | 466 Amino acids |
Molecular weight | 51466 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1970822 2 PubMed abstract 1966743 |
Hormone | N/A |
Gene ID | 282134 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20745 |
Swiss-prot Accession number | Q9WU25 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 51578 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11527538 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20746 |
Swiss-prot Accession number | P35348 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor) (Alpha adrenergicreceptor 1c). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart. |
Post translational modification | Carboxyl-terminal Ser or Thr residues may be phosphorylated (By similarity). |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. |
Protein Length | 466 Amino acids |
Molecular weight | 51487 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8396931 2 PubMed abstract 8024574 3 PubMed abstract 8183249 4 PubMed abstract 8564208 5 PubMed abstract 7815325 6 PubMed abstract 7737411 7 PubMed abstract 9490024 8 PubMed abstract 10493934 9 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 10 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 11 PubMed abstract 8832064 12 PubMed abstract 15179408 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 148 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20747 |
Swiss-prot Accession number | P97718 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Carboxyl-terminal Ser or Thr residues may be phosphorylated (By similarity). |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. |
Protein Length | 466 Amino acids |
Molecular weight | 51763 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9630362 2 PubMed abstract 7595531 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20748 |
Swiss-prot Accession number | Q91175 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (MAR1). |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity). |
Protein Length | 470 Amino acids |
Molecular weight | 51925 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8654394 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20749 |
Swiss-prot Accession number | O02824 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor). |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Abundant in liver, vas deferens, brain, and aorta, but not in heart. |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. |
Protein Length | 466 Amino acids |
Molecular weight | 51365 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9180361 |
Hormone | N/A |
Gene ID | 100009237 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20750 |
Swiss-prot Accession number | P43140 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor (Alpha 1A-adrenoceptor) (Alpha 1A-adrenoreceptor) (Alpha-1C adrenergic receptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Abundant in heart, brain, aorta, vena cava, vas deferens, submaxillary gland, lung, and kidney. Found at lower levels in prostate, parotid gland and skeletal muscle. |
Post translational modification | Carboxyl-terminal Ser or Thr residues may be phosphorylated (By similarity). |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. |
Protein Length | 466 Amino acids |
Molecular weight | 51598 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7923624 2 PubMed abstract 7935320 3 PubMed abstract 8185565 |
Hormone | N/A |
Gene ID | 29412 |
PDB ID | 2F75 |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20751 |
Swiss-prot Accession number | P35368 (Sequence in FASTA format) |
Description | Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B-adrenoreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 520 Amino acids |
Molecular weight | 56836 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1328250 2 PubMed abstract 8183249 3 PubMed abstract 7815325 |
Hormone | Detail in HMRbase |
Gene ID | 147 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20752 |
Swiss-prot Accession number | P18841 (Sequence in FASTA format) |
Description | Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B-adrenoreceptor). |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 515 Amino acids |
Molecular weight | 56493 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2845398 2 PubMed abstract 1346134 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20753 |
Swiss-prot Accession number | P97717 (Sequence in FASTA format) |
Description | Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B-adrenoreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 514 Amino acids |
Molecular weight | 56418 |
Domain Name | 7tm_1 |
References | 1 Cotecchia S., Lattion-Zellweger A.; Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 7595531 3 PubMed abstract 17242355 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20754 |
Swiss-prot Accession number | P15823 (Sequence in FASTA format) |
Description | Alpha-1B adrenergic receptor (Alpha 1B-adrenoceptor) (Alpha 1B-adrenoreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 515 Amino acids |
Molecular weight | 56586 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2156222 2 PubMed abstract 1706716 3 PubMed abstract 8406017 4 PubMed abstract 7989580 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20755 |
Swiss-prot Accession number | P25100 (Sequence in FASTA format) |
Description | Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor) (Alpha-1A adrenergic receptor) (Alpha adrenergicreceptor 1a). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. |
Protein Length | 572 Amino acids |
Molecular weight | 60463 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1656955 2 PubMed abstract 8183249 3 PubMed abstract 7815325 4 PubMed abstract 8024574 5 PubMed abstract 7746284 6 PubMed abstract 11780052 |
Hormone | Detail in HMRbase |
Gene ID | 146 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20756 |
Swiss-prot Accession number | P97714 (Sequence in FASTA format) |
Description | Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor) (Alpha-1A adrenergic receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. |
Protein Length | 562 Amino acids |
Molecular weight | 59858 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7595531 2 PubMed abstract 10622215 3 PubMed abstract 8288218 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20757 |
Swiss-prot Accession number | O02666 (Sequence in FASTA format) |
Description | Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor). |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. |
Protein Length | 576 Amino acids |
Molecular weight | 60267 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9030207 |
Hormone | N/A |
Gene ID | 100009398 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20758 |
Swiss-prot Accession number | P23944 (Sequence in FASTA format) |
Description | Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor) (Alpha-1A adrenergic receptor) (RA42). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Vas deferens, hippocampus, cerebral cortex, aorta, brain stem, heart and spleen. |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium. |
Protein Length | 561 Amino acids |
Molecular weight | 59354 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1706716 2 PubMed abstract 1661838 3 PubMed abstract 7815325 4 PubMed abstract 10570042 |
Hormone | N/A |
Gene ID | 29413 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20759 |
Swiss-prot Accession number | Q28838 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR) (Alpha-2D adrenergic receptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Retina, brain and olfactory lobe. |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 452 Amino acids |
Molecular weight | 49252 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9450652 2 PubMed abstract 8412494 |
Hormone | N/A |
Gene ID | 282135 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20760 |
Swiss-prot Accession number | Q60474 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 450 Amino acids |
Molecular weight | 48911 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8573196 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20761 |
Swiss-prot Accession number | P08913 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR) (Alpha-2 adrenergic receptor subtypeC10). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. |
Protein Length | 450 Amino acids |
Molecular weight | 48957 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2568356 2 PubMed abstract 2823383 3 PubMed abstract 2170371 4 PubMed abstract 10948191 5 PubMed abstract 16567612 6 Mao Z.-M., Tang K., Li B.-M., Jing N.-H.; "Cloning and expression of human alpha-2A adrenergic receptor in SY5Ycells."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 7 Castellano M., Giacche' M., Rossi F., Rivadossi F., Perani C.,Beschi M., Agabiti Rosei E.; "A search for genetic variability in the human alpha-2 adrenergicreceptor on chromosome 10."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 8 Liu L., Yuan L.; "Human alpha-2A adrenergic receptor gene and the genotype of -1296nucleotide and motionsickness."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. 9 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 10 PubMed abstract 15164054 11 PubMed abstract 15489334 12 PubMed abstract 1849485 13 PubMed abstract 1678390 14 PubMed abstract 1678850 15 PubMed abstract 17081983 16 PubMed abstract 11888275 17 PubMed abstract 2568356 18 PubMed abstract 2823383 19 PubMed abstract 2170371 20 PubMed abstract 10948191 21 PubMed abstract 16567612 22 Mao Z.-M., Tang K., Li B.-M., Jing N.-H.; "Cloning and expression of human alpha-2A adrenergic receptor in SY5Ycells."; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 23 Castellano M., Giacche' M., Rossi F., Rivadossi F., Perani C.,Beschi M., Agabiti Rosei E.; "A search for genetic variability in the human alpha-2 adrenergicreceptor on chromosome 10."; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 24 Liu L., Yuan L.; "Human alpha-2A adrenergic receptor gene and the genotype of -1296nucleotide and motionsickness."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases. 25 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. 26 PubMed abstract 15164054 27 PubMed abstract 15489334 28 PubMed abstract 1849485 29 PubMed abstract 1678390 30 PubMed abstract 1678850 31 PubMed abstract 17081983 32 PubMed abstract 11888275 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 150 |
PDB ID | 1HLL 1HO9 1HOD 1HOF |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20762 |
Swiss-prot Accession number | Q01338 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 450 Amino acids |
Molecular weight | 48865 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1353249 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20763 |
Swiss-prot Accession number | P18871 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 450 Amino acids |
Molecular weight | 48976 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2170371 2 PubMed abstract 8385131 |
Hormone | N/A |
Gene ID | 399501 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20764 |
Swiss-prot Accession number | P22909 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha-2AAR) (CA2-47) (Alpha-2D adrenergic receptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 450 Amino acids |
Molecular weight | 48940 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1645350 2 PubMed abstract 2177834 3 PubMed abstract 7623790 |
Hormone | N/A |
Gene ID | 25083 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20765 |
Swiss-prot Accession number | Q60475 (Sequence in FASTA format) |
Description | Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 448 Amino acids |
Molecular weight | 49597 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8573196 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20766 |
Swiss-prot Accession number | P18089 (Sequence in FASTA format) |
Description | Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (Alpha-2 adrenergic receptor subtype C2). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol. |
Protein Length | 450 Amino acids |
Molecular weight | 49954 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2164221 2 PubMed abstract 2172775 3 PubMed abstract 11056163 4 PubMed abstract 15037199 5 Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for adrenergic receptor alpha2B (ADRA2B)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 6 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 15815621 8 PubMed abstract 2173582 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 151 |
PDB ID | 2CVA |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20767 |
Swiss-prot Accession number | P30545 (Sequence in FASTA format) |
Description | Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 450 Amino acids |
Molecular weight | 50172 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1336396 2 PubMed abstract 1354956 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20768 |
Swiss-prot Accession number | P19328 (Sequence in FASTA format) |
Description | Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 453 Amino acids |
Molecular weight | 50369 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2158103 2 Schaak S., Cussac D., Paris H.; "Cloning and characterization of the rat alpha2B-adrenergic receptorgene promoter."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7755946 |
Hormone | N/A |
Gene ID | 24174 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20769 |
Swiss-prot Accession number | Q60476 (Sequence in FASTA format) |
Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 455 Amino acids |
Molecular weight | 49351 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8573196 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20770 |
Swiss-prot Accession number | P35405 (Sequence in FASTA format) |
Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor). |
Source organism | Didelphis marsupialis virginiana (North American opossum) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Metatheria; Didelphimorphia; Didelphidae; Didelphis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 469 Amino acids |
Molecular weight | 53223 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7509437 2 Bylund D.B.; Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20771 |
Swiss-prot Accession number | P18825 (Sequence in FASTA format) |
Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha-2 adrenergic receptor subtype C4). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 462 Amino acids |
Molecular weight | 49522 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2842764 2 PubMed abstract 9371698 3 Yano K., Takeda M., Sugimoto E., Sagai H.; "Molecular cloning and expression of a novel human alpha2C-adrenergincreceptor, alpha2CII, gene."; Submitted (OCT-1992) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 10801795 5 PubMed abstract 15319474 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for adrenergic receptor alpha2C (ADRA2C)."; Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 1849485 |
Hormone | Detail in HMRbase |
Gene ID | 152 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20772 |
Swiss-prot Accession number | Q01337 (Sequence in FASTA format) |
Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha-2 adrenergic receptor subtype C4). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 458 Amino acids |
Molecular weight | 49906 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1353249 2 PubMed abstract 8387367 |
Hormone | N/A |
Gene ID | 100045767 11553 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20773 |
Swiss-prot Accession number | P22086 (Sequence in FASTA format) |
Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha-2 adrenergic receptor subtype C4). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 458 Amino acids |
Molecular weight | 49864 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1704126 2 PubMed abstract 1704314 3 PubMed abstract 1645350 4 Saitoh M., Imai A., Shimomura H.; "Cloning of rat alpha-2-B-adrenergic receptor gene and expression inrat submandibular gland."; Shigaku 80:317-326(1992). |
Hormone | N/A |
Gene ID | 24175 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20774 |
Swiss-prot Accession number | P43141 (Sequence in FASTA format) |
Description | Beta-4C adrenergic receptor (Beta-4C adrenoceptor) (Beta-4Cadrenoreceptor). |
Source organism | Meleagris gallopavo (Common turkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Meleagris. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Broad tissue distribution. |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. |
Protein Length | 428 Amino acids |
Molecular weight | 47398 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7929160 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20775 |
Swiss-prot Accession number | P32251 (Sequence in FASTA format) |
Description | Alpha-2 adrenergic receptor (Alpha-2 adrenoceptor) (Alpha-2adrenoreceptor). |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 436 Amino acids |
Molecular weight | 49258 |
Domain Name | 7tm_1 |
References | 1 Shih Y.-L., Chang N.-C.A., Chang A.C., Lo S.J.; "Molecular cloning and expression of goldfish adrenoceptor."; Submitted (JUL-1993) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20776 |
Swiss-prot Accession number | Q91081 (Sequence in FASTA format) |
Description | Alpha-2 adrenergic receptor (Alpha-2 adrenoceptor) (Alpha-2adrenoreceptor). |
Source organism | Labrus ossifagus (Cuckoo wrasse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Labridae; Labrus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. |
Protein Length | 432 Amino acids |
Molecular weight | 48563 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7693288 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20777 |
Swiss-prot Accession number | Q9TT96 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity). |
Protein Length | 467 Amino acids |
Molecular weight | 50137 |
Domain Name | 7tm_1 |
References | 1 Ha S.H., Baik M.G., Choi Y.J.; "Cloning of beta adrenergic receptor from Korean cattle."; Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
2 Ha S.H.; "Cloning and characterization of beta adrenergic receptor from Koreannative cattle."; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20778 |
Swiss-prot Accession number | P79148 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Protein Length | 473 Amino acids |
Molecular weight | 50061 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9220370 |
Hormone | N/A |
Gene ID | 493972 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20779 |
Swiss-prot Accession number | Q9TST6 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity). |
Protein Length | 474 Amino acids |
Molecular weight | 50533 |
Domain Name | 7tm_1 |
References | 1 Cully D.F., Tremml G., Zachwieja S.; "Felis domesticus beta adrenergic receptor subtype 1."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 493971 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20780 |
Swiss-prot Accession number | P08588 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein. Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Protein Length | 477 Amino acids |
Molecular weight | 51323 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2825170 2 PubMed abstract 10477438 3 Rieder M.J., Daniels R.L., da Ponte S.H., Hastings N.C., Ahearn M.O.,Rajkumar N., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15358775 5 PubMed abstract 10212248 6 PubMed abstract 11052857 7 PubMed abstract 11854867 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20781 |
Swiss-prot Accession number | P47899 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Protein Length | 480 Amino acids |
Molecular weight | 51609 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7987008 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20782 |
Swiss-prot Accession number | P07700 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor) (Beta-T). |
Source organism | Meleagris gallopavo (Common turkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Meleagris. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximatively equal affinity. |
Protein Length | 483 Amino acids |
Molecular weight | 54078 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 3018746 2 PubMed abstract 7828722 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | 1DEP |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20783 |
Swiss-prot Accession number | P34971 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Protein Length | 466 Amino acids |
Molecular weight | 50480 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8395893 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20784 |
Swiss-prot Accession number | Q28998 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity). |
Protein Length | 468 Amino acids |
Molecular weight | 50098 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9655595 2 PubMed abstract 10229356 |
Hormone | N/A |
Gene ID | 397355 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20785 |
Swiss-prot Accession number | P18090 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Protein Length | 466 Amino acids |
Molecular weight | 50472 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1695899 2 PubMed abstract 2167473 |
Hormone | N/A |
Gene ID | 24925 |
PDB ID | 2FF9 |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20786 |
Swiss-prot Accession number | Q28927 (Sequence in FASTA format) |
Description | Beta-1 adrenergic receptor (Beta-1 adrenoceptor) (Beta-1adrenoreceptor) (BETA1AR). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. |
Protein Length | 467 Amino acids |
Molecular weight | 50272 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7779093 2 PubMed abstract 8606964 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20787 |
Swiss-prot Accession number | Q28044 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 47136 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10342858 2 Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases. 3 Stoffel B., Hagen-Mann K., Mann W., Meyer H.H.D.; Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 281605 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20788 |
Swiss-prot Accession number | P54833 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Protein Length | 415 Amino acids |
Molecular weight | 46589 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8880434 2 PubMed abstract 9220370 |
Hormone | N/A |
Gene ID | 403910 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20789 |
Swiss-prot Accession number | Q9TST5 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 46736 |
Domain Name | 7tm_1 |
References | 1 Cully D.F., Tremml G., Zachwieja S.; "Felis domesticus beta adrenergic receptor subtype 2."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 493767 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20790 |
Swiss-prot Accession number | P07550 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation. Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Protein Length | 413 Amino acids |
Molecular weight | 46557 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 3033609 2 PubMed abstract 3025863 3 PubMed abstract 3026848 4 PubMed abstract 2823249 5 PubMed abstract 3034889 6 Rupert J.R., Hochachka P.W.; "Beta-2-adrenergic receptor allele frequencies in two native Americanpopulations."; Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases. 7 Puhl H.L. III, Ikeda S.R., Aronstam R.S.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases. 8 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 2831218 10 PubMed abstract 2540197 11 PubMed abstract 11146000 12 PubMed abstract 10499588 13 PubMed abstract 12142540 14 PubMed abstract 8383511 15 PubMed abstract 7915137 16 PubMed abstract 7706471 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 154 |
PDB ID | 2R4R 2R4S 3D4S |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20791 |
Swiss-prot Accession number | Q28509 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 415 Amino acids |
Molecular weight | 46472 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7669252 |
Hormone | N/A |
Gene ID | 710146 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20792 |
Swiss-prot Accession number | P04274 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Protein Length | 418 Amino acids |
Molecular weight | 46861 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 3010132 2 PubMed abstract 2162359 3 PubMed abstract 2547766 4 PubMed abstract 2899076 5 PubMed abstract 1318386 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20793 |
Swiss-prot Accession number | P18762 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Protein Length | 418 Amino acids |
Molecular weight | 47002 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2834198 2 PubMed abstract 2549959 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20794 |
Swiss-prot Accession number | Q8UUY8 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Highly expressed in the liver and red and white muscle, with lower levels of expression in the gills, heart, kidney and spleen. |
Post translational modification | Lacks the regulatory protein kinase A phosphorylation sites within the G-protein binding domain that mediate desensitization and are present in mammalian homologs. |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 409 Amino acids |
Molecular weight | 45098 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11737201 |
Hormone | N/A |
Gene ID | 100136153 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20795 |
Swiss-prot Accession number | Q28997 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 46760 |
Domain Name | 7tm_1 |
References | 1 Liang W., Bidwell C.A., Williams S.K., Mills S.E.; "Molecular cloning of the porcine beta-2-adrenergic receptor gene."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
2 Li W.F., Nie C., Zhou X.X., Lu P., Yao J.T., Feng J.; "Molecular cloning of the porcine beta-2-adrenergic receptor gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 10229356 |
Hormone | N/A |
Gene ID | 397357 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20796 |
Swiss-prot Accession number | P10608 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Protein Length | 418 Amino acids |
Molecular weight | 46891 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2825184 2 PubMed abstract 2155412 3 PubMed abstract 7590294 4 PubMed abstract 8597598 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20797 |
Swiss-prot Accession number | P46626 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 405 Amino acids |
Molecular weight | 42903 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7601122 2 PubMed abstract 10834601 3 Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases. 4 Stoffel B., Meyer H.H.D.; "Bovine beta3-adrenergic receptor, partial genomic sequence."; Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 7904157 |
Hormone | N/A |
Gene ID | 281606 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20798 |
Swiss-prot Accession number | O02662 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 405 Amino acids |
Molecular weight | 43051 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9881593 2 Thompson G.M., Kelly L.J., Candelore M.R.; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 442979 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20799 |
Swiss-prot Accession number | Q9XT57 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Capra hircus (Goat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Capra. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 405 Amino acids |
Molecular weight | 43126 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10834601 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20800 |
Swiss-prot Accession number | Q9TST4 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis (By similarity). |
Protein Length | 398 Amino acids |
Molecular weight | 41978 |
Domain Name | 7tm_1 |
References | 1 Cully D.F., Tremml G., Zachwieja S.; "Felis domesticus beta adrenergic receptor subunit 3."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 493930 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20801 |
Swiss-prot Accession number | P13945 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed mainly in adipose tissues. |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 408 Amino acids |
Molecular weight | 43519 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2570461 2 PubMed abstract 8389293 3 PubMed abstract 8389717 4 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases. 5 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 7 PubMed abstract 1336117 8 PubMed abstract 7609752 9 PubMed abstract 8721782 10 PubMed abstract 8641219 11 PubMed abstract 10391210 |
Hormone | Detail in HMRbase |
Gene ID | 155 |
PDB ID | 2CDW |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20802 |
Swiss-prot Accession number | Q28524 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 418 Amino acids |
Molecular weight | 44657 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9133593 2 Thompson G.M., Kelly L.J., Candelore M.R.; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 699129 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20803 |
Swiss-prot Accession number | P25962 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | White and brown adipose tissues, and digestive tract. Isoform B highest in brain. |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 400 Amino acids |
Molecular weight | 43006 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1718744 2 PubMed abstract 8389293 3 PubMed abstract 10455305 4 PubMed abstract 1336117 |
Hormone | N/A |
Gene ID | 11556 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20804 |
Swiss-prot Accession number | P26255 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | White and brown adipose tissues, and digestive tract. |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 400 Amino acids |
Molecular weight | 43146 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1721063 2 PubMed abstract 1684635 3 PubMed abstract 8382630 |
Hormone | N/A |
Gene ID | 25645 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20805 |
Swiss-prot Accession number | Q9XT58 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 405 Amino acids |
Molecular weight | 42928 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10834601 2 PubMed abstract 12580782 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20806 |
Swiss-prot Accession number | Q2VA56 (Sequence in FASTA format) |
Description | Alpha-1A adrenoreceptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 478 Amino acids |
Molecular weight | 52844 |
Domain Name | 7tm_1 |
References | 1 Moon T.W., Perry S.F., Chen X.; "Molecular characterization of alpha-1 adrenoreceptor gene family androle in blood pressure regulation in rainbow trout (Oncorhynchusmykiss)."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100136682 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20807 |
Swiss-prot Accession number | Q2XPQ2 (Sequence in FASTA format) |
Description | Beta 3 adrenergic receptor. |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis (By similarity). |
Protein Length | 405 Amino acids |
Molecular weight | 42941 |
Domain Name | 7tm_1 |
References | 1 Wynyard J.R., Forrest R.H., Merrick N.C., Hickford J.G.; Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20808 |
Swiss-prot Accession number | Q2XQ07 (Sequence in FASTA format) |
Description | Beta 3 adrenergic reecptor. |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis (By similarity). |
Protein Length | 405 Amino acids |
Molecular weight | 42928 |
Domain Name | 7tm_1 |
References | 1 Wynyard J.R., Forrest R.H., Merrick N.C., Hickford J.G.; "Ovis aries beta 3 adrenergic receptor - allele G."; Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20811 |
Swiss-prot Accession number | Q3UP63 (Sequence in FASTA format) |
Description | 6 days neonate spleen cDNA, RIKEN full-length enriched library,clone:F430106H21 product:adrenergic receptor, beta 3, full insertsequence (Adult male cecum cDNA, RIKEN full-length enriched library,clone:9130002F08 product:adrenergic receptor, beta 3, full insertsequence). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis (By similarity). |
Protein Length | 400 Amino acids |
Molecular weight | 43006 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 11556 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20812 |
Swiss-prot Accession number | Q3URE6 (Sequence in FASTA format) |
Description | Adult male hippocampus cDNA, RIKEN full-length enriched library,clone:C630032H01 product:adrenergic receptor, alpha 2a, full insertsequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 465 Amino acids |
Molecular weight | 50555 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 11551 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20813 |
Swiss-prot Accession number | Q4KWL2 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Beta-2 adrenoceptor) (Beta-2adrenoreceptor). |
Source organism | Tscherskia triton (Greater long-tailed hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Tscherskia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylated; may reduce accessibility of Ser-345 and Ser- 346 by anchoring Cys-341 to the plasma membrane. Agonist stimulation promotes depalmitoylation and further allows Ser-345 and Ser-346 phosphorylation (By similarity). Phosphorylated by PKA and BARK upon agonist stimulation, which mediates homologous desensitization of the receptor. PKA- mediated phosphorylation seems to facilitate phosphorylation by BARK (By similarity). |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 47039 |
Domain Name | 7tm_1 |
References | 1 Yang S.M., Song R., Cheng X.G.; "Cloning and functional analysis of beta2 adrenergic receptor fromgreater long-tailed hamster."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20814 |
Swiss-prot Accession number | Q4VBM7 (Sequence in FASTA format) |
Description | Adrenergic, alpha-1A-, receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 51512 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20815 |
Swiss-prot Accession number | Q5T5Y4 (Sequence in FASTA format) |
Description | Adrenergic, beta-1-, receptor. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity (By similarity). |
Protein Length | 477 Amino acids |
Molecular weight | 51224 |
Domain Name | 7tm_1 |
References | 1 Heath P.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 153 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20816 |
Swiss-prot Accession number | Q5ZQK3 (Sequence in FASTA format) |
Description | Alpha 2A adrenoceptor. |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 451 Amino acids |
Molecular weight | 49301 |
Domain Name | 7tm_1 |
References | 1 Bruss M., Bonisch H., Gothert M., Molderings G.J.; "Molecular identification of the rabbit alpha 2A adrenoceptor."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
2 Bruess M.; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 100009424 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20817 |
Swiss-prot Accession number | Q6GMT4 (Sequence in FASTA format) |
Description | Adrenergic, beta-2-, receptor, surface. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 413 Amino acids |
Molecular weight | 46459 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20818 |
Swiss-prot Accession number | Q6IRH4 (Sequence in FASTA format) |
Description | Adrenergic receptor, alpha 1b. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity). |
Protein Length | 515 Amino acids |
Molecular weight | 56558 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 24173 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20819 |
Swiss-prot Accession number | Q6XQJ1 (Sequence in FASTA format) |
Description | Beta-3b-adrenergic receptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 477 Amino acids |
Molecular weight | 53262 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12775554 |
Hormone | N/A |
Gene ID | 100136173 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20820 |
Swiss-prot Accession number | Q6XQJ2 (Sequence in FASTA format) |
Description | Beta-3a-adrenergic receptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 427 Amino acids |
Molecular weight | 47895 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12775554 |
Hormone | N/A |
Gene ID | 100136655 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20821 |
Swiss-prot Accession number | Q7T077 (Sequence in FASTA format) |
Description | Putative beta-2 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 417 Amino acids |
Molecular weight | 47337 |
Domain Name | 7tm_1 |
References | 1 Lagerstrom M.C., Klovins J., Fredriksson R., Fridmanis D., Haitina T.,Ling M.K., Berglund M.M., Schioth H.B.; "High affinity agonistic metal ion binding site within themelanocortin 4 receptor illustrates conformational changes of TM3during binding and activation."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20822 |
Swiss-prot Accession number | Q8BH38 (Sequence in FASTA format) |
Description | Adrenergic receptor, beta 2 (Adult male aorta and vein cDNA, RIKENfull-length enriched library, clone:A530087O16 product:BETA-2ADRENERGIC RECEPTOR, full insert sequence). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 46998 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 10349636 4 PubMed abstract 16141072 5 PubMed abstract 16141073 6 PubMed abstract 12466851 7 PubMed abstract 11217851 8 PubMed abstract 11042159 9 PubMed abstract 11076861 10 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 11555 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20823 |
Swiss-prot Accession number | Q8BUE5 (Sequence in FASTA format) |
Description | 0 day neonate kidney cDNA, RIKEN full-length enriched library,clone:D630050N06 product:adrenergic receptor, alpha 1a, ALPHA 1A-ADRENOCEPTOR, full insert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 427 Amino acids |
Molecular weight | 47516 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20824 |
Swiss-prot Accession number | Q8BV77 (Sequence in FASTA format) |
Description | Adult male spinal cord cDNA, RIKEN full-length enriched library,clone:A330054N11 product:ALPHA 1A-ADRENERGIC RECEPTOR, full insertsequence (Adra1a protein). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 51744 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 12477932 10 Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 11549 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20825 |
Swiss-prot Accession number | Q8BXZ4 (Sequence in FASTA format) |
Description | 7 days neonate cerebellum cDNA, RIKEN full-length enriched library,clone:A730021M07 product:ALPHA-1A ADRENERGIC RECEPTOR (ALPHA 1A-ADRENOCEPTOR) (ALPHA-1C ADRENERGIC RECEPTOR) homolog. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 295 Amino acids |
Molecular weight | 32463 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20826 |
Swiss-prot Accession number | Q8HY79 (Sequence in FASTA format) |
Description | Alpha-2A adrenoceptor. |
Source organism | Tupaia glis belangeri (Common tree shrew) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 450 Amino acids |
Molecular weight | 49150 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11032999 2 Fluegge G., Meyer H.; Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20827 |
Swiss-prot Accession number | Q8HYY8 (Sequence in FASTA format) |
Description | Alpha-2B adrenoceptor. |
Source organism | Tupaia glis belangeri (Common tree shrew) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 451 Amino acids |
Molecular weight | 50356 |
Domain Name | 7tm_1 |
References | 1 Heilbronner U., van Kampen M., Isovich E., Fluegge G.; "Thalamic alpha-2B adrenoceptors under chronic stress: persistentupregulation in the paraventricular nucleus."; Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20828 |
Swiss-prot Accession number | Q8JG00 (Sequence in FASTA format) |
Description | Alpha2 d2 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins (By similarity). |
Protein Length | 471 Amino acids |
Molecular weight | 52527 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20829 |
Swiss-prot Accession number | Q8JG01 (Sequence in FASTA format) |
Description | Alpha2 d1 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 420 Amino acids |
Molecular weight | 47560 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20830 |
Swiss-prot Accession number | Q8JG02 (Sequence in FASTA format) |
Description | Alpha2 c2 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins (By similarity). |
Protein Length | 420 Amino acids |
Molecular weight | 47218 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20831 |
Swiss-prot Accession number | Q8JG03 (Sequence in FASTA format) |
Description | Alpha2 a2 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 417 Amino acids |
Molecular weight | 47199 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20832 |
Swiss-prot Accession number | Q8JG04 (Sequence in FASTA format) |
Description | Alpha2 b2 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 465 Amino acids |
Molecular weight | 50760 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20833 |
Swiss-prot Accession number | Q8JG05 (Sequence in FASTA format) |
Description | Alpha2 b1 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 510 Amino acids |
Molecular weight | 55691 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20834 |
Swiss-prot Accession number | Q8JG06 (Sequence in FASTA format) |
Description | Alpha2 c1 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins (By similarity). |
Protein Length | 447 Amino acids |
Molecular weight | 51138 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20835 |
Swiss-prot Accession number | Q8JG07 (Sequence in FASTA format) |
Description | Alpha2 a1 adrenergic receptor. |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 388 Amino acids |
Molecular weight | 44031 |
Domain Name | 7tm_1 |
References | 1 Hunter C.I.; Thesis (2001), Department of Genetics, University of Cambridge,Cambridge, United Kingdom.
2 Hunter C.I., Harrow I.D., Elgar G.; "Evolution of the vertebrate alpha-2 adrenergic receptor family."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20836 |
Swiss-prot Accession number | Q8K4Z4 (Sequence in FASTA format) |
Description | Beta2-adrenergic receptor. |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 46991 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12460637 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20837 |
Swiss-prot Accession number | Q8VBU7 (Sequence in FASTA format) |
Description | Beta-2 adrenergic receptor (Adrenergic receptor, beta 2). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity). |
Protein Length | 418 Amino acids |
Molecular weight | 46960 |
Domain Name | 7tm_1 |
References | 1 Pravenec M., Zidek V., Kostka V., Mlejnek P., Musilova A., Kren V.,Jansa P., Forejt J., Lezin E.S., Kurtz T.W.; "Genetic isolation of a QTL on chromosome 18 associated with saltsensitivity in spontaneously hypertensive rats."; Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 12477932 3 Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 24176 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20838 |
Swiss-prot Accession number | Q925K6 (Sequence in FASTA format) |
Description | Adrenergic receptor alpha 2B. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 448 Amino acids |
Molecular weight | 49999 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11471062 2 Lovell J.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20839 |
Swiss-prot Accession number | Q96RE8 (Sequence in FASTA format) |
Description | Adrenergic receptor alpha-1a. |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 51431 |
Domain Name | 7tm_1 |
References | 1 Banerjee A.G.N., Aarti A.; "RT-PCR cloning and sequence analysis of adrenergic receptor subtype-alpha-1a cDNA from human prostrate cell-line DU-145."; Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20840 |
Swiss-prot Accession number | Q9DBL0 (Sequence in FASTA format) |
Description | Adult male liver cDNA, RIKEN full-length enriched library,clone:1300003P04 product:ADRENERGIC RECEPTOR, ALPHA 1B, full insertsequence (Adrenergic receptor, alpha 1b) (10 days neonate cortex cDNA,RIKEN full-length enriched library, clone:A830044N22product:ADRENERGIC RECEPTOR, ALPHA 1B, full insert sequence). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity). |
Protein Length | 515 Amino acids |
Molecular weight | 56498 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H.,Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M.,Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F.,Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H.,Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C.,Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M.,Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K.,Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T.,Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T.,Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M.,Muramatsu M., Hayashizaki Y.; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. 9 Lovell J.; Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. 10 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 11548 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20841 |
Swiss-prot Accession number | Q9MYI8 (Sequence in FASTA format) |
Description | Alpha 1b adrenoceptor. |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system (By similarity). |
Protein Length | 518 Amino acids |
Molecular weight | 56645 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10822047 |
Hormone | N/A |
Gene ID | 100008731 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20842 |
Swiss-prot Accession number | Q95252 (Sequence in FASTA format) |
Description | Beta-3 adrenergic receptor (Beta-3 adrenoceptor) (Beta-3adrenoreceptor). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | White and brown adipose tissues. |
Post translational modification | N/A |
Function | Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis. |
Protein Length | 407 Amino acids |
Molecular weight | 43611 |
Domain Name | 7tm_1 |
References | 1 Smith T.R., Bidwell C.A., Mills S.E.; "Sus scrofa beta-3-adrenergic receptor (BAR3) gene."; Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 7592080 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20843 |
Swiss-prot Accession number | Q9MZU2 (Sequence in FASTA format) |
Description | Alpha 1a-adrenoceptor isoform 3. |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 425 Amino acids |
Molecular weight | 47009 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10780960 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20844 |
Swiss-prot Accession number | Q9MZU3 (Sequence in FASTA format) |
Description | Alpha 1a-adrenoceptor isoform 2. |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 429 Amino acids |
Molecular weight | 47464 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10780960 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20845 |
Swiss-prot Accession number | Q9QW71 (Sequence in FASTA format) |
Description | Alpha 1-adrenergic receptor subtype alpha 1D, alpha 1D-AR. |
Source organism | Rattus sp. |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus; unclassified Rattus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium (By similarity). |
Protein Length | 559 Amino acids |
Molecular weight | 59739 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1661838 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20846 |
Swiss-prot Accession number | Q9TSW7 (Sequence in FASTA format) |
Description | Alpha-1A adrenergic receptor. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins (By similarity). |
Protein Length | 466 Amino acids |
Molecular weight | 51675 |
Domain Name | 7tm_1 |
References | 1 Uhlen S., Wraith A.; "Characterization of the pig alpha-1A adrenergic receptor."; Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | N/A |
Gene ID | 100144471 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20847 |
Swiss-prot Accession number | O42385 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A-alpha receptor (5-HT-1A-alpha) (Serotoninreceptor 1A-alpha) (5-HT1A-alpha) (F1A). |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 423 Amino acids |
Molecular weight | 47001 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9218723 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20848 |
Swiss-prot Accession number | O42384 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1A-beta receptor (5-HT-1A-beta) (Serotoninreceptor 1A-beta) (5-HT1A-beta) (F1B). |
Source organism | Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Tetraodontiformes;Tetradontoidea; Tetraodontidae; Takifugu. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity (By similarity). |
Protein Length | 416 Amino acids |
Molecular weight | 47031 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9218723 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20849 |
Swiss-prot Accession number | Q8JG70 (Sequence in FASTA format) |
Description | Alpha-2Da adrenergic receptor (Alpha-2Da adrenoceptor) (Alpha-2Daadrenoreceptor) (Alpha(2Da)AR). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine > oxymetazoline. |
Protein Length | 408 Amino acids |
Molecular weight | 46199 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20850 |
Swiss-prot Accession number | Q8JG69 (Sequence in FASTA format) |
Description | Alpha-2Db adrenergic receptor (Alpha-2Db adrenoceptor) (Alpha-2Dbadrenoreceptor) (Alpha(2Db)AR). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine = epinephrine > oxymetazoline. |
Protein Length | 415 Amino acids |
Molecular weight | 46863 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
Hormone | N/A |
Gene ID | 266755 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20851 |
Swiss-prot Accession number | Q90WY4 (Sequence in FASTA format) |
Description | Alpha-2A adrenergic receptor (Alpha-2A adrenoceptor) (Alpha-2Aadrenoreceptor) (Alpha(2A)AR). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > oxymetazoline = epinephrine > norepinephrine. |
Protein Length | 388 Amino acids |
Molecular weight | 43997 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20852 |
Swiss-prot Accession number | Q90WY5 (Sequence in FASTA format) |
Description | Alpha-2B adrenergic receptor (Alpha-2B adrenoceptor) (Alpha-2Badrenoreceptor) (Alpha(2B)AR). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is norepinephrine > epinephrine. |
Protein Length | 510 Amino acids |
Molecular weight | 55971 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
Hormone | N/A |
Gene ID | 266751 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20853 |
Swiss-prot Accession number | Q90WY6 (Sequence in FASTA format) |
Description | Alpha-2C adrenergic receptor (Alpha-2C adrenoceptor) (Alpha-2Cadrenoreceptor) (Alpha(2C)AR). |
Source organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Danio. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > norepinephrine > epinephrine. |
Protein Length | 432 Amino acids |
Molecular weight | 49137 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12949138 2 PubMed abstract 15655522 |
Hormone | N/A |
Gene ID | 266752 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20855 |
Swiss-prot Accession number | P56494 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 389 Amino acids |
Molecular weight | 42914 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9493565 2 PubMed abstract 9493565 |
Hormone | N/A |
Gene ID | 702048 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20862 |
Swiss-prot Accession number | P47901 (Sequence in FASTA format) |
Description | Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor)(AVPR V3) (Antidiuretic hormone receptor 1b). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. |
Protein Length | 424 Amino acids |
Molecular weight | 46971 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7929452 2 PubMed abstract 7805841 3 PubMed abstract 9357056 4 PubMed abstract 9581826 5 PubMed abstract 10607899 6 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 16710414 8 PubMed abstract 7929452 9 PubMed abstract 7805841 10 PubMed abstract 9357056 11 PubMed abstract 9581826 12 PubMed abstract 10607899 13 Rieder M.J., Johanson E.J., da Ponte S.H., Hastings N.C., Ahearn M.O.,Bertucci C.B., Wong M.W., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. 14 PubMed abstract 16710414 |
Hormone | N/A |
Gene ID | 553 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20863 |
Swiss-prot Accession number | Q9WU02 (Sequence in FASTA format) |
Description | Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor)(AVPR V3) (Antidiuretic hormone receptor 1b). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. |
Protein Length | 421 Amino acids |
Molecular weight | 46539 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10343284 2 PubMed abstract 10669045 3 PubMed abstract 10343284 4 PubMed abstract 10669045 |
Hormone | N/A |
Gene ID | 26361 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20864 |
Swiss-prot Accession number | P48974 (Sequence in FASTA format) |
Description | Vasopressin V1b receptor (V1bR) (AVPR V1b) (Vasopressin V3 receptor)(AVPR V3) (Antidiuretic hormone receptor 1b). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. |
Protein Length | 425 Amino acids |
Molecular weight | 47086 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7626108 2 PubMed abstract 7624319 3 PubMed abstract 7626108 4 PubMed abstract 7624319 |
Hormone | N/A |
Gene ID | 29462 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20865 |
Swiss-prot Accession number | P48044 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 370 Amino acids |
Molecular weight | 40236 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7698346 2 PubMed abstract 8257689 3 PubMed abstract 7698346 4 PubMed abstract 8257689 |
Hormone | N/A |
Gene ID | 281642 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20866 |
Swiss-prot Accession number | O77808 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 370 Amino acids |
Molecular weight | 40200 |
Domain Name | 7tm_1 |
References | 1 Weber B.I.L., Rascher W.; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
2 Weber B.I.L., Rascher W.; "Organization of the dog vasopressin receptor gene."; Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases. 3 Weber B.I.L., Rascher W.; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases. 4 Weber B.I.L., Rascher W.; "Organization of the dog vasopressin receptor gene."; Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 403804 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20867 |
Swiss-prot Accession number | P30518 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Kidney. |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 371 Amino acids |
Molecular weight | 40279 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1534149 2 PubMed abstract 1415251 3 PubMed abstract 8735975 4 PubMed abstract 9581826 5 Warren C.N., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 7 PubMed abstract 9224808 8 PubMed abstract 1356229 9 PubMed abstract 1303271 10 PubMed abstract 1303257 11 PubMed abstract 8267567 12 PubMed abstract 8479490 13 PubMed abstract 8514744 14 PubMed abstract 8037205 15 PubMed abstract 7999078 16 PubMed abstract 7987330 17 PubMed abstract 7833930 18 PubMed abstract 8045948 19 PubMed abstract 7984150 20 PubMed abstract 8078903 21 PubMed abstract 7560098 22 PubMed abstract 9402087 23 PubMed abstract 9452109 24 PubMed abstract 10694923 25 PubMed abstract 9711877 26 PubMed abstract 10770218 27 PubMed abstract 11026555 28 PubMed abstract 11232028 29 PubMed abstract 11916004 30 PubMed abstract 15872203 31 PubMed abstract 1534149 32 PubMed abstract 1415251 33 PubMed abstract 8735975 34 PubMed abstract 9581826 35 Warren C.N., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 36 PubMed abstract 15489334 37 PubMed abstract 9224808 38 PubMed abstract 1356229 39 PubMed abstract 1303271 40 PubMed abstract 1303257 41 PubMed abstract 8267567 42 PubMed abstract 8479490 43 PubMed abstract 8514744 44 PubMed abstract 8037205 45 PubMed abstract 7999078 46 PubMed abstract 7987330 47 PubMed abstract 7833930 48 PubMed abstract 8045948 49 PubMed abstract 7984150 50 PubMed abstract 8078903 51 PubMed abstract 7560098 52 PubMed abstract 9402087 53 PubMed abstract 9452109 54 PubMed abstract 10694923 55 PubMed abstract 9711877 56 PubMed abstract 10770218 57 PubMed abstract 11026555 58 PubMed abstract 11232028 59 PubMed abstract 11916004 60 PubMed abstract 15872203 61 PubMed abstract 1534149 62 PubMed abstract 1415251 63 PubMed abstract 8735975 64 PubMed abstract 9581826 65 Warren C.N., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 66 PubMed abstract 15489334 67 PubMed abstract 9224808 68 PubMed abstract 1356229 69 PubMed abstract 1303271 70 PubMed abstract 1303257 71 PubMed abstract 8267567 72 PubMed abstract 8479490 73 PubMed abstract 8514744 74 PubMed abstract 8037205 75 PubMed abstract 7999078 76 PubMed abstract 7987330 77 PubMed abstract 7833930 78 PubMed abstract 8045948 79 PubMed abstract 7984150 80 PubMed abstract 8078903 81 PubMed abstract 7560098 82 PubMed abstract 9402087 83 PubMed abstract 9452109 84 PubMed abstract 10694923 85 PubMed abstract 9711877 86 PubMed abstract 10770218 87 PubMed abstract 11026555 88 PubMed abstract 11232028 89 PubMed abstract 11916004 90 PubMed abstract 15872203 |
Hormone | N/A |
Gene ID | 554 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20868 |
Swiss-prot Accession number | O88721 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 371 Amino acids |
Molecular weight | 40645 |
Domain Name | 7tm_1 |
References | 1 Guenther G., Eichhorst J., Krause G., Rosenthal W., Oksche A.; "Structure and functional expression of the mouse vasopressin V2receptor gene."; Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
2 Platzer M., Brenner V., Reichwald K., Wiehe T., Oksche A.,Rosenthal A.; "Comparative sequence analysis of the mouse L1cam locus and thecorresponding region of human Xq28."; Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. 3 Oksche A., Leder G., Rosenthal W.; "Species differences in vasopressin V2 receptors: mRNA tissuedistribution and functional properties of the human and murinereceptors."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 4 Guenther G., Eichhorst J., Krause G., Rosenthal W., Oksche A.; "Structure and functional expression of the mouse vasopressin V2receptor gene."; Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases. 5 Platzer M., Brenner V., Reichwald K., Wiehe T., Oksche A.,Rosenthal A.; "Comparative sequence analysis of the mouse L1cam locus and thecorresponding region of human Xq28."; Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases. 6 Oksche A., Leder G., Rosenthal W.; "Species differences in vasopressin V2 receptors: mRNA tissuedistribution and functional properties of the human and murinereceptors."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 12000 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20869 |
Swiss-prot Accession number | P32307 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 370 Amino acids |
Molecular weight | 40537 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8393786 2 PubMed abstract 8393786 |
Hormone | N/A |
Gene ID | 397462 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20870 |
Swiss-prot Accession number | Q00788 (Sequence in FASTA format) |
Description | Vasopressin V2 receptor (Renal-type arginine vasopressin receptor)(Antidiuretic hormone receptor) (AVPR V2). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Kidney. |
Post translational modification | N/A |
Function | Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 371 Amino acids |
Molecular weight | 40749 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1534150 2 PubMed abstract 7708485 3 Terry R., Mullins D.; "Rat vasopressin 2 receptor gene DNA sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 1534150 5 PubMed abstract 7708485 6 Terry R., Mullins D.; "Rat vasopressin 2 receptor gene DNA sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 1534150 8 PubMed abstract 7708485 9 Terry R., Mullins D.; "Rat vasopressin 2 receptor gene DNA sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | 25108 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20871 |
Swiss-prot Accession number | P70115 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Mesocricetus auratus (Golden hamster) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Cricetidae; Cricetinae; Mesocricetus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. |
Protein Length | 297 Amino acids |
Molecular weight | 34034 |
Domain Name | 7tm_1 |
References | 1 Fleury A., Cloutier M., Ducharme L., LeHoux J.-G.; Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
2 Fleury A., Cloutier M., Ducharme L., LeHoux J.-G.; Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20877 |
Swiss-prot Accession number | P56442 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alces alces alces (European moose) (Elk) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Cervidae; Odocoileinae; Alces. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34982 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20878 |
Swiss-prot Accession number | Q864K5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Allenopithecus nigroviridis (Allen's swamp monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Allenopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34795 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20879 |
Swiss-prot Accession number | Q864G3 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alouatta caraya (Black howler monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Atelidae; Alouattinae; Alouatta. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34693 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20880 |
Swiss-prot Accession number | Q6A155 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alopex lagopus (Arctic fox) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Alopex. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34887 |
Domain Name | 7tm_1 |
References | 1 Vage D.; "A MC1R mutation prevent expression of the winter white coat phenotypeof the arctic fox (Alopex lagopus)."; Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
2 Vage D.; "A MC1R mutation prevent expression of the winter white coat phenotypeof the arctic fox (Alopex lagopus)."; Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20881 |
Swiss-prot Accession number | Q864G2 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alouatta palliata (Mantled howler monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Atelidae; Alouattinae; Alouatta. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34671 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20882 |
Swiss-prot Accession number | Q864G1 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alouatta pigra (Guatemalan howler monkey) (Mexican black howlermonkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Atelidae; Alouattinae; Alouatta. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34729 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20883 |
Swiss-prot Accession number | Q864G4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alouatta sara (Bolivian red howler monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Atelidae; Alouattinae; Alouatta. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34687 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20884 |
Swiss-prot Accession number | Q864G6 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Alouatta seniculus (Red howler monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Atelidae; Alouattinae; Alouatta. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34831 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20885 |
Swiss-prot Accession number | Q864G7 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Ateles paniscus (Black spider monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Atelidae; Atelinae; Ateles. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34721 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20886 |
Swiss-prot Accession number | Q864H9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Callithrix argentata (Black-tailed marmoset) (Silvery marmoset) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Callithrix. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 344 Amino acids |
Molecular weight | 37531 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20887 |
Swiss-prot Accession number | Q864H8 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Callithrix geoffroyi (Geoffroy's marmoset) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Callithrix. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 344 Amino acids |
Molecular weight | 37523 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20888 |
Swiss-prot Accession number | Q864H6 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Callimico goeldii (Goeldi's marmoset) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Callimico. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 344 Amino acids |
Molecular weight | 37583 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20889 |
Swiss-prot Accession number | Q864H7 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Callithrix jacchus (Common marmoset) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Callithrix. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 344 Amino acids |
Molecular weight | 37575 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20890 |
Swiss-prot Accession number | O77616 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34984 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10895310 2 PubMed abstract 10895310 |
Hormone | N/A |
Gene ID | 489652 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20891 |
Swiss-prot Accession number | P56443 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Capreolus capreolus (Roe deer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Cervidae; Odocoileinae; Capreolus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34939 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20892 |
Swiss-prot Accession number | P56444 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Capra hircus (Goat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Capra. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34860 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20893 |
Swiss-prot Accession number | Q864G9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cebus albifrons (White-fronted capuchin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Cebinae; Cebus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 316 Amino acids |
Molecular weight | 34757 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20894 |
Swiss-prot Accession number | Q864I0 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cebuella pygmaea (Pygmy marmoset) (Callithrix pygmaea) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Callithrix. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 344 Amino acids |
Molecular weight | 37630 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20895 |
Swiss-prot Accession number | Q864K2 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cercopithecus aethiops (Green monkey) (Grivet) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34772 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 3 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20896 |
Swiss-prot Accession number | Q864K0 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cercopithecus diana (Diana monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Cercopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34815 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20897 |
Swiss-prot Accession number | P56445 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cervus elaphus (Red deer) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Cervidae; Cervinae; Cervus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34914 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20898 |
Swiss-prot Accession number | Q864J9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cercopithecus mitis (Blue monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Cercopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34775 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20899 |
Swiss-prot Accession number | Q864K1 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Cercopithecus neglectus (Debrazza's monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Cercopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34764 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20900 |
Swiss-prot Accession number | Q80SS9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Chaetodipus baileyi (Bailey's pocket mouse) (Perognathus baileyi) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 35492 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12704245 2 PubMed abstract 12704245 3 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20901 |
Swiss-prot Accession number | Q80SZ5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Chaetodipus penicillatus (Desert pocket mouse) (Perognathuspenicillatus) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Heteromyidae; Perognathinae; Chaetodipus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 35389 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12704245 2 PubMed abstract 12704245 3 PubMed abstract 12704245 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20902 |
Swiss-prot Accession number | P55167 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 314 Amino acids |
Molecular weight | 35297 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8634326 2 PubMed abstract 8634326 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20903 |
Swiss-prot Accession number | Q864J0 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Colobus guereza (Black-and-white colobus monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Colobus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34710 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20904 |
Swiss-prot Accession number | P56446 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Dama dama (Fallow deer) (Cervus dama) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Cervidae; Cervinae; Dama. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34911 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20905 |
Swiss-prot Accession number | Q864K3 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Erythrocebus patas (Red guenon) (Cercopithecus patas) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Erythrocebus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34837 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20906 |
Swiss-prot Accession number | Q864F6 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Eulemur fulvus fulvus (Brown lemur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Lemuriformes; Lemuridae; Eulemur. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34749 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20907 |
Swiss-prot Accession number | Q865E9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Felis silvestris catus (Cat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34752 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12620197 2 PubMed abstract 12620197 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20908 |
Swiss-prot Accession number | Q864F9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Galago senegalensis (Northern lesser bushbaby) (Senegal bushbaby) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Lorisiformes; Galagidae; Galago. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34606 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20909 |
Swiss-prot Accession number | Q864K9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Gorilla gorilla gorilla (Lowland gorilla) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Gorilla. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 316 Amino acids |
Molecular weight | 34692 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Roy R., Cantero M., Jimenez-Cervantes C., Garcia-Borron J.C.,Montoliu L.; "Analysis of 5' upstream regulatory sequences and LCR-like region ofthe Gorilla tyrosinase locus."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Roy R., Cantero M., Jimenez-Cervantes C., Garcia-Borron J.C.,Montoliu L.; "Analysis of 5' upstream regulatory sequences and LCR-like region ofthe Gorilla tyrosinase locus."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 12687585 6 Roy R., Cantero M., Jimenez-Cervantes C., Garcia-Borron J.C.,Montoliu L.; "Analysis of 5' upstream regulatory sequences and LCR-like region ofthe Gorilla tyrosinase locus."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20910 |
Swiss-prot Accession number | Q864F5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Hapalemur griseus (Gray gentle lemur) (Bamboo lemur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Lemuriformes; Lemuridae; Hapalemur. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34424 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20911 |
Swiss-prot Accession number | Q865E5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Herpailurus yaguarondi (Jaguarundi) (Felis yagouaroundi) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Herpailurus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34750 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12620197 2 PubMed abstract 12620197 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20912 |
Swiss-prot Accession number | P79166 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Equus caballus (Horse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 317 Amino acids |
Molecular weight | 35213 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11353392 2 PubMed abstract 8995760 3 PubMed abstract 11353392 4 PubMed abstract 8995760 |
Hormone | N/A |
Gene ID | 100136907 |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20913 |
Swiss-prot Accession number | Q864K6 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Hylobates concolor (Crested gibbon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hylobatidae; Nomascus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34776 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20914 |
Swiss-prot Accession number | Q864K8 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Hylobates lar (Common gibbon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hylobatidae; Hylobates. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34824 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20915 |
Swiss-prot Accession number | Q864K7 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Hylobates muelleri (Mueller's gibbon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hylobatidae; Hylobates. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34790 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20916 |
Swiss-prot Accession number | Q864F4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Lemur catta (Ring-tailed lemur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Lemuriformes; Lemuridae; Lemur. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34668 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20917 |
Swiss-prot Accession number | Q864I2 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Leontopithecus chrysopygus (Gold-and-black lion tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Leontopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 318 Amino acids |
Molecular weight | 35080 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20918 |
Swiss-prot Accession number | Q864I1 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Leontopithecus chrysomelas (Golden-headed lion tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Leontopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 310 Amino acids |
Molecular weight | 34196 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20919 |
Swiss-prot Accession number | Q864I3 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Leontopithecus rosalia (Golden lion tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Leontopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 318 Amino acids |
Molecular weight | 35080 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20920 |
Swiss-prot Accession number | Q864G0 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Loris tardigradus (Slender loris) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Chiromyiformes; Lorisidae; Loris. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34590 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20921 |
Swiss-prot Accession number | Q864J4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34764 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20922 |
Swiss-prot Accession number | Q864J5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Macaca nigra (Celebes black macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34780 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20923 |
Swiss-prot Accession number | Q864J7 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Macaca silenus (Lion-tailed macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34783 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20924 |
Swiss-prot Accession number | Q864J6 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Macaca sylvanus (Barbary ape) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34733 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 3 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20925 |
Swiss-prot Accession number | Q0Q460 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Mammuthus primigenius (Siberian woolly mammoth) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Mammuthus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34944 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16825562 2 PubMed abstract 16825562 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20926 |
Swiss-prot Accession number | Q864J1 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Mandrillus sphinx (Mandrill) (Papio sphinx) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34779 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20927 |
Swiss-prot Accession number | Q864K4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Miopithecus talapoin (Talapoin) (Cercopithecus talapoin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Miopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34765 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20928 |
Swiss-prot Accession number | P56447 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Ovibos moschatus (Muskox) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovibos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34876 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20929 |
Swiss-prot Accession number | Q865E8 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Panthera onca (Jaguar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Pantherinae; Panthera. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34722 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12620197 2 PubMed abstract 12620197 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20930 |
Swiss-prot Accession number | Q9TUK4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Pan troglodytes (Chimpanzee) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pan. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34700 |
Domain Name | 7tm_1 |
References | 1 Rees J.L., Harding R.M., Healy E., Jackson I.J., Ray A.J., Ellis N.S.,Flanagan N., Todd C., Dixon C., Matthews J.N., Sajantila A.,Birch-MacHin M.A.; "Chimpanzee melanocortin 1 sequence."; Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 12687585 3 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 4 Rees J.L., Harding R.M., Healy E., Jackson I.J., Ray A.J., Ellis N.S.,Flanagan N., Todd C., Dixon C., Matthews J.N., Sajantila A.,Birch-MacHin M.A.; "Chimpanzee melanocortin 1 sequence."; Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 12687585 6 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20931 |
Swiss-prot Accession number | Q864J3 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Papio anubis (Olive baboon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Papio. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34779 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20932 |
Swiss-prot Accession number | Q864J2 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Papio hamadryas (Hamadryas baboon) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Papio. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34751 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20933 |
Swiss-prot Accession number | Q864L0 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Pongo pygmaeus (Orangutan) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Pongo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34750 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20934 |
Swiss-prot Accession number | Q864I9 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Presbytis comata (Grizzled leaf monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Presbytis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34634 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20935 |
Swiss-prot Accession number | P56448 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Rangifer tarandus (Reindeer) (Caribou) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Cervidae; Odocoileinae; Rangifer. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34895 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20936 |
Swiss-prot Accession number | Q864H4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Saguinus fuscicollis (Brown-headed tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Saguinus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 316 Amino acids |
Molecular weight | 34718 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20937 |
Swiss-prot Accession number | Q864H3 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Saguinus geoffroyi (Geoffroy's tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Saguinus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 316 Amino acids |
Molecular weight | 34766 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20938 |
Swiss-prot Accession number | Q864H5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Saguinus imperator (Emperor tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Saguinus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34848 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20939 |
Swiss-prot Accession number | Q864H1 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Saguinus midas (Black-handed tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Saguinus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34861 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20940 |
Swiss-prot Accession number | Q864H2 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Saguinus oedipus (Cotton-top tamarin) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Callitrichinae; Saguinus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34851 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20941 |
Swiss-prot Accession number | Q864H0 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Saimiri oerstedii (Central American squirrel monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Platyrrhini; Cebidae; Saimiriinae; Saimiri. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34820 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20942 |
Swiss-prot Accession number | Q864I8 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Semnopithecus entellus (Hanuman langur) (Presbytis entellus) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Semnopithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34819 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 12687585 4 Nakayama K., Shotake T., Takenaka O., Ishida T.; "Variation of the melanocortin 1 receptor gene in the macaques."; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20943 |
Swiss-prot Accession number | Q864I7 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Trachypithecus auratus (Javan langur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Trachypithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34756 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20944 |
Swiss-prot Accession number | Q864I6 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Trachypithecus cristatus (Silvered leaf monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Trachypithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34756 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20945 |
Swiss-prot Accession number | Q864I4 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Trachypithecus francoisi (Francois' langur) (Indochinese langur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Trachypithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34772 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20946 |
Swiss-prot Accession number | Q864I5 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Trachypithecus obscurus (Dusky leaf monkey) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Colobinae; Trachypithecus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34806 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20947 |
Swiss-prot Accession number | Q864F8 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Varecia variegata rubra (Red ruffed lemur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Lemuriformes; Lemuridae; Varecia. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34715 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20948 |
Swiss-prot Accession number | Q864F7 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Varecia variegata variegata (Black and white ruffed lemur) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;Lemuriformes; Lemuridae; Varecia. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34715 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20949 |
Swiss-prot Accession number | Q29154 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Vulpes vulpes (Red fox) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Vulpes. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 317 Amino acids |
Molecular weight | 34869 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9054949 2 PubMed abstract 9054949 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20952 |
Swiss-prot Accession number | P30796 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Praomys natalensis (African soft-furred rat) (Mastomys natalensis) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mastomys. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Stomach and brain. |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 450 Amino acids |
Molecular weight | 48755 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1530611 2 PubMed abstract 1530611 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20953 |
Swiss-prot Accession number | P46627 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Oryctolagus cuniculus (Rabbit) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae;Oryctolagus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 452 Amino acids |
Molecular weight | 48730 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8048969 2 PubMed abstract 8048969 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20959 |
Swiss-prot Accession number | O19037 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a role in the regulation of dominant black coat color in sheep. |
Protein Length | 317 Amino acids |
Molecular weight | 34919 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10628296 2 PubMed abstract 10628296 |
Hormone | P01191 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20963 |
Swiss-prot Accession number | Q7T1P8 (Sequence in FASTA format) |
Description | Cholecystokinin receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 436 Amino acids |
Molecular weight | 47749 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12763638 2 Nilsson I.B.; Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q9PU41 Detail in HMRbase |
Gene ID | 414885 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20964 |
Swiss-prot Accession number | Q3TPL0 (Sequence in FASTA format) |
Description | 12 days embryo spinal ganglion cDNA, RIKEN full-length enrichedlibrary, clone:D130015H10 product:cholecystokinin A receptor, fullinsert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 365 Amino acids |
Molecular weight | 40474 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P09240 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20966 |
Swiss-prot Accession number | Q32XW8 (Sequence in FASTA format) |
Description | Ecdysis triggering hormone receptor subtype-B. |
Source organism | Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Sphingoidea;Sphingidae; Sphinginae; Manduca. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 558 Amino acids |
Molecular weight | 63393 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16968777 2 Kim Y.-J., Cho K.-H., Zitnan D., Adams M.E.; "Identification of Ecdysis Triggering Hormone Receptors in Manducasexta."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P11919 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20968 |
Swiss-prot Accession number | Q3UY93 (Sequence in FASTA format) |
Description | Adult male olfactory brain cDNA, RIKEN full-length enriched library,clone:6430411D18 product:G protein coupled receptor 24, full insertsequence (Melanin-concentrating hormone receptor 1). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 353 Amino acids |
Molecular weight | 39120 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K.,Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S.,Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N.,Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D.,Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A.,Muramatsu M., Hayashizaki Y.; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 9 PubMed abstract 12477932 10 Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | P56942 Detail in HMRbase |
Gene ID | 207911 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20970 |
Swiss-prot Accession number | O08725 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine) (By similarity). |
Protein Length | 364 Amino acids |
Molecular weight | 40963 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9092793 2 PubMed abstract 9437732 3 PubMed abstract 10604470 |
Hormone | Q9QYH7 Detail in HMRbase |
Gene ID | 84022 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20972 |
Swiss-prot Accession number | O08858 (Sequence in FASTA format) |
Description | Somatostatin receptor type 5 (SS5R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatin-28. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
Protein Length | 362 Amino acids |
Molecular weight | 39948 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9300821 2 Moldovan S., DeMayo F., Brunicardi F.C.; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. 3 Gordon D.F., Woodmansee W.W., Wood W.M., Knauf H., James R.A.; Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases. 4 Baumeister H., Roosterman D., Schafer J., Kreuzer O., Meyerhof W.; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 9300821 6 Moldovan S., DeMayo F., Brunicardi F.C.; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases. 7 Gordon D.F., Woodmansee W.W., Wood W.M., Knauf H., James R.A.; Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases. 8 Baumeister H., Roosterman D., Schafer J., Kreuzer O., Meyerhof W.; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | P60041 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20973 |
Swiss-prot Accession number | O42329 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
Source organism | Clarias gariepinus (Sharptooth catfish) (African catfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;Clariidae; Clarias. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 379 Amino acids |
Molecular weight | 42771 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9030732 2 Bogerd J.; Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases. |
Hormone | P43306 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20978 |
Swiss-prot Accession number | O93603 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 395 Amino acids |
Molecular weight | 44698 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9681487 |
Hormone | Q6ZXC3 Detail in HMRbase |
Gene ID | 395770 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20994 |
Swiss-prot Accession number | P21729 (Sequence in FASTA format) |
Description | Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesinreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain (hypothalamus), pancreatic acinar cells, and fibroblasts. |
Post translational modification | N/A |
Function | Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 384 Amino acids |
Molecular weight | 43215 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1671171 2 PubMed abstract 1707129 3 PubMed abstract 8391296 |
Hormone | Q8R1I2 Detail in HMRbase |
Gene ID | 14829 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 20995 |
Swiss-prot Accession number | P21761 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 393 Amino acids |
Molecular weight | 44559 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 2175902 2 PubMed abstract 1324930 3 PubMed abstract 9156522 |
Hormone | Q62361 Detail in HMRbase |
Gene ID | 22045 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21001 |
Swiss-prot Accession number | P28646 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 (SS1R) (SRIF-2). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain, pituitary, islet, jejunum, stomach, heart, spleen. |
Post translational modification | N/A |
Function | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled to phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. |
Protein Length | 391 Amino acids |
Molecular weight | 42746 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1661599 2 PubMed abstract 1400442 3 PubMed abstract 1661599 4 PubMed abstract 1400442 |
Hormone | P60042 Detail in HMRbase |
Gene ID | 25033 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21003 |
Swiss-prot Accession number | P30550 (Sequence in FASTA format) |
Description | Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesinreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Highly expressed in pancreas. Also expressed in stomach, adrenal cortex and brain. |
Post translational modification | N/A |
Function | Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 384 Amino acids |
Molecular weight | 43199 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1655761 2 PubMed abstract 11245983 3 PubMed abstract 15489334 |
Hormone | P07492 Detail in HMRbase |
Gene ID | 2925 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21005 |
Swiss-prot Accession number | P30552 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Parietal cells, pancreas, brain and various neoplastic tissues. |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 453 Amino acids |
Molecular weight | 48519 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1373504 2 Song I., Blandizzi C., Brown D.R., Kang D.H., Todisco A., Delvalle J.,del Tacca M., Owyang C., Yamada T.; "Molecular cloning and structural analysis of the canine gastrin/CCK-Breceptor gene."; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 1373504 4 Song I., Blandizzi C., Brown D.R., Kang D.H., Todisco A., Delvalle J.,del Tacca M., Owyang C., Yamada T.; "Molecular cloning and structural analysis of the canine gastrin/CCK-Breceptor gene."; Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01353 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21006 |
Swiss-prot Accession number | P30553 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Parietal cells, pancreas, brain and various neoplastic tissues. |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 452 Amino acids |
Molecular weight | 48957 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1528881 2 PubMed abstract 1528881 |
Hormone | P01355 Detail in HMRbase P04563 Detail in HMRbase |
Gene ID | 25706 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21007 |
Swiss-prot Accession number | P30559 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 389 Amino acids |
Molecular weight | 42772 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1313946 2 Kimura T., Tanizawa O., Mori K., Brownstein M.J., Okayama H.; Nature 357:176-176(1992). 3 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 7798245 5 PubMed abstract 1313946 6 Kimura T., Tanizawa O., Mori K., Brownstein M.J., Okayama H.; Nature 357:176-176(1992). 7 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 7798245 |
Hormone | P01178 Detail in HMRbase |
Gene ID | 5021 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21008 |
Swiss-prot Accession number | P30680 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Cortex, hippocampus, pituitary gland, colon adrenals, pancreas-derived cell line and pancreatic tumor. |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Protein Length | 369 Amino acids |
Molecular weight | 41200 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1374909 2 PubMed abstract 1348934 3 PubMed abstract 8386508 4 PubMed abstract 1374909 5 PubMed abstract 1348934 6 PubMed abstract 8386508 |
Hormone | P60042 Detail in HMRbase |
Gene ID | 54305 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21010 |
Swiss-prot Accession number | P30872 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 (SS1R) (SRIF-2). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach. |
Post translational modification | N/A |
Function | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. |
Protein Length | 391 Amino acids |
Molecular weight | 42686 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1346068 2 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 15489334 4 PubMed abstract 10734105 5 PubMed abstract 1346068 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 15489334 8 PubMed abstract 10734105 |
Hormone | P61278 Detail in HMRbase |
Gene ID | 6751 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21011 |
Swiss-prot Accession number | P30873 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 (SS1R) (SRIF-2). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Jejunum and stomach. |
Post translational modification | N/A |
Function | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. |
Protein Length | 391 Amino acids |
Molecular weight | 42718 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1346068 2 PubMed abstract 1346068 |
Hormone | P60041 Detail in HMRbase |
Gene ID | 20605 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21012 |
Swiss-prot Accession number | P30874 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Cerebrum and kidney. In lesser amounts in jejunum, colon and liver. |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Protein Length | 369 Amino acids |
Molecular weight | 41333 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1346068 2 PubMed abstract 10619399 3 Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for somatostatin receptor 2(SSTR2)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 4 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 15489334 7 PubMed abstract 8386508 8 PubMed abstract 10551867 9 PubMed abstract 1346068 10 PubMed abstract 10619399 11 Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for somatostatin receptor 2(SSTR2)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 12 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 13 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 14 PubMed abstract 15489334 15 PubMed abstract 8386508 16 PubMed abstract 10551867 17 PubMed abstract 1346068 18 PubMed abstract 10619399 19 Kopatz S.A., Aronstam R.S., Sharma S.V.; "Isolation of complete coding sequence for somatostatin receptor 2(SSTR2)."; Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. 20 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 21 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 22 PubMed abstract 15489334 23 PubMed abstract 8386508 24 PubMed abstract 10551867 |
Hormone | P61278 Detail in HMRbase |
Gene ID | 6752 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21013 |
Swiss-prot Accession number | P30875 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Cerebrum and kidney. |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Protein Length | 369 Amino acids |
Molecular weight | 41222 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1346068 2 PubMed abstract 1397330 3 PubMed abstract 11278805 4 PubMed abstract 7913111 5 PubMed abstract 8104154 6 PubMed abstract 1346068 7 PubMed abstract 1397330 8 PubMed abstract 11278805 9 PubMed abstract 7913111 10 PubMed abstract 8104154 |
Hormone | P60041 Detail in HMRbase |
Gene ID | 20606 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21014 |
Swiss-prot Accession number | P30935 (Sequence in FASTA format) |
Description | Somatostatin receptor type 3 (SS3R) (SSR-28). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity). |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. |
Protein Length | 428 Amino acids |
Molecular weight | 47391 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1328199 2 PubMed abstract 1328199 |
Hormone | P60041 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21015 |
Swiss-prot Accession number | P30936 (Sequence in FASTA format) |
Description | Somatostatin receptor type 3 (SS3R) (SSR-28). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Densely expressed in cerebellum and in moderate levels in the amygdala, cortex, striatum, spleen, liver, pituitary. |
Post translational modification | Phosphorylated. Phosphorylation increases upon somatostatin binding. |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. |
Protein Length | 428 Amino acids |
Molecular weight | 47151 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1279674 2 PubMed abstract 9295322 3 PubMed abstract 1279674 4 PubMed abstract 9295322 |
Hormone | P60042 Detail in HMRbase |
Gene ID | 171044 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21016 |
Swiss-prot Accession number | P30937 (Sequence in FASTA format) |
Description | Somatostatin receptor type 4 (SS4R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain, lung, heart and islets. Moderate levels in the hippocampus, cortex and olfactory bulb. |
Post translational modification | N/A |
Function | Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. |
Protein Length | 384 Amino acids |
Molecular weight | 42088 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1360663 2 PubMed abstract 8175684 3 PubMed abstract 1360663 4 PubMed abstract 8175684 |
Hormone | P60042 Detail in HMRbase |
Gene ID | 25555 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21017 |
Swiss-prot Accession number | P30938 (Sequence in FASTA format) |
Description | Somatostatin receptor type 5 (SS5R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Prominent in the pituitary and small intestine. Low levels in islets and spleen. Not detected in kidney, pancreas, cerebellum, or cortex. |
Post translational modification | N/A |
Function | Receptor for somatostatin-28. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
Protein Length | 363 Amino acids |
Molecular weight | 39971 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1362243 2 PubMed abstract 7908405 3 PubMed abstract 1362243 4 PubMed abstract 7908405 |
Hormone | P60042 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21018 |
Swiss-prot Accession number | P30968 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary, ovary, testis, breast and prostate but not in liver and spleen. |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act a an inhibitor of GnRH-R signaling. |
Protein Length | 328 Amino acids |
Molecular weight | 37731 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1333190 2 PubMed abstract 8386108 3 PubMed abstract 7534732 4 PubMed abstract 9272108 5 PubMed abstract 9259321 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 15489334 8 PubMed abstract 10366411 9 PubMed abstract 9371856 10 PubMed abstract 9425890 11 PubMed abstract 10022417 12 PubMed abstract 10084584 13 PubMed abstract 10523035 14 PubMed abstract 11397842 15 PubMed abstract 11318785 16 PubMed abstract 11397871 17 PubMed abstract 11994356 18 PubMed abstract 12679486 |
Hormone | O43555 Detail in HMRbase P01148 Detail in HMRbase Q6X4W1 Detail in HMRbase |
Gene ID | 2798 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21019 |
Swiss-prot Accession number | P30969 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 327 Amino acids |
Molecular weight | 37748 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1338727 2 Kakar S.S., Grantham K., Musgrove L.C., Devor D.C., Sellers J.C.,Neill J.D.; Submitted (AUG-1993) to the EMBL/GenBank/DDBJ databases. 3 PubMed abstract 7916600 4 PubMed abstract 1339279 5 PubMed abstract 8185587 6 PubMed abstract 7764374 7 Reinhart J., Xiao S., Arora K.K., Catt K.J.; Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases. |
Hormone | P07490 Detail in HMRbase Q9EPI6 Detail in HMRbase |
Gene ID | 81668 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21021 |
Swiss-prot Accession number | P31391 (Sequence in FASTA format) |
Description | Somatostatin receptor type 4 (SS4R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals. |
Post translational modification | N/A |
Function | Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells. |
Protein Length | 388 Amino acids |
Molecular weight | 41895 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8512564 2 PubMed abstract 8483934 3 PubMed abstract 8373420 4 PubMed abstract 8100352 5 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 11780052 7 PubMed abstract 15489334 8 PubMed abstract 8512564 9 PubMed abstract 8483934 10 PubMed abstract 8373420 11 PubMed abstract 8100352 12 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. 13 PubMed abstract 11780052 14 PubMed abstract 15489334 |
Hormone | P61278 Detail in HMRbase |
Gene ID | 6754 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21025 |
Swiss-prot Accession number | P32237 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 328 Amino acids |
Molecular weight | 37685 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7694577 2 PubMed abstract 8224516 3 PubMed abstract 8666259 |
Hormone | Q28588 Detail in HMRbase |
Gene ID | 443413 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21027 |
Swiss-prot Accession number | P32239 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 447 Amino acids |
Molecular weight | 48419 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7681836 2 PubMed abstract 1280419 3 PubMed abstract 8415658 4 PubMed abstract 8349705 5 Tate S.N., Gray J., Denyer J., Stolz M., Foord S., Lee M.G.; Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases. 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 7 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 11926817 9 PubMed abstract 7681836 10 PubMed abstract 1280419 11 PubMed abstract 8415658 12 PubMed abstract 8349705 13 Tate S.N., Gray J., Denyer J., Stolz M., Foord S., Lee M.G.; Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases. 14 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 15 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 16 PubMed abstract 11926817 |
Hormone | P01350 Detail in HMRbase P06307 Detail in HMRbase |
Gene ID | 887 |
PDB ID | 1L4T |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21028 |
Swiss-prot Accession number | P32306 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 386 Amino acids |
Molecular weight | 42524 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8393786 2 PubMed abstract 8393786 |
Hormone | P01177 Detail in HMRbase |
Gene ID | 397092 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21029 |
Swiss-prot Accession number | P32745 (Sequence in FASTA format) |
Description | Somatostatin receptor type 3 (SS3R) (SSR-28). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain, pituitary and pancreas. |
Post translational modification | Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity). |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. |
Protein Length | 418 Amino acids |
Molecular weight | 45847 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1337145 2 PubMed abstract 8097479 3 Rasch A.C., Boehnke C., Petersenn S.; "The human somatostatin receptor subtype 3 contains an upstream exonin the 5'-untranslated region: functional promoter studies."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 4 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 15461802 6 PubMed abstract 10591208 7 PubMed abstract 15489334 8 PubMed abstract 1337145 9 PubMed abstract 8097479 10 Rasch A.C., Boehnke C., Petersenn S.; "The human somatostatin receptor subtype 3 contains an upstream exonin the 5'-untranslated region: functional promoter studies."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 11 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 12 PubMed abstract 15461802 13 PubMed abstract 10591208 14 PubMed abstract 15489334 15 PubMed abstract 1337145 16 PubMed abstract 8097479 17 Rasch A.C., Boehnke C., Petersenn S.; "The human somatostatin receptor subtype 3 contains an upstream exonin the 5'-untranslated region: functional promoter studies."; Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases. 18 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases. 19 PubMed abstract 15461802 20 PubMed abstract 10591208 21 PubMed abstract 15489334 |
Hormone | P61278 Detail in HMRbase |
Gene ID | 6753 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21030 |
Swiss-prot Accession number | P34974 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Melanocytes and corticoadrenal tissue. |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 297 Amino acids |
Molecular weight | 33293 |
Domain Name | 7tm_1 |
References | 1 Cone R.D., Mountjoy K.G.; "Molecular genetics of the ACTH and melanocyte-stimulating hormonereceptors."; Trends Endocrinol. Metab. 4:26-31(1993).
2 PubMed abstract 8305507 3 Cone R.D., Mountjoy K.G.; "Molecular genetics of the ACTH and melanocyte-stimulating hormonereceptors."; Trends Endocrinol. Metab. 4:26-31(1993). 4 PubMed abstract 8305507 |
Hormone | P01190 Detail in HMRbase |
Gene ID | 281299 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21031 |
Swiss-prot Accession number | P34981 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 398 Amino acids |
Molecular weight | 45085 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8395824 2 PubMed abstract 8396925 3 PubMed abstract 8243797 4 PubMed abstract 7918619 5 PubMed abstract 8703031 6 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 15489334 8 PubMed abstract 9886052 9 PubMed abstract 8770906 10 PubMed abstract 8395824 11 PubMed abstract 8396925 12 PubMed abstract 8243797 13 PubMed abstract 7918619 14 PubMed abstract 8703031 15 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. 16 PubMed abstract 15489334 17 PubMed abstract 9886052 18 PubMed abstract 8770906 |
Hormone | P20396 Detail in HMRbase |
Gene ID | 7201 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21032 |
Swiss-prot Accession number | P34993 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Protein Length | 368 Amino acids |
Molecular weight | 41134 |
Domain Name | 7tm_1 |
References | 1 Xin W.W., Wong M.-L., Rimland J., Nestler E.J., Duman R.S.; "Characterization and functional expression of a somatostatin receptorisolated from locus Coeruleus."; Submitted (NOV-1992) to the EMBL/GenBank/DDBJ databases.
2 Xin W.W., Wong M.-L., Rimland J., Nestler E.J., Duman R.S.; "Characterization and functional expression of a somatostatin receptorisolated from locus Coeruleus."; Submitted (NOV-1992) to the EMBL/GenBank/DDBJ databases. |
Hormone | P26917 Detail in HMRbase |
Gene ID | 282083 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21033 |
Swiss-prot Accession number | P34994 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R) (SRIF-1). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. |
Protein Length | 369 Amino acids |
Molecular weight | 41219 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8123027 2 PubMed abstract 8123027 |
Hormone | P01168 Detail in HMRbase |
Gene ID | 497059 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21036 |
Swiss-prot Accession number | P35346 (Sequence in FASTA format) |
Description | Somatostatin receptor type 5 (SS5R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. |
Post translational modification | N/A |
Function | Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. |
Protein Length | 364 Amino acids |
Molecular weight | 39202 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7908405 2 PubMed abstract 8373420 3 PubMed abstract 8078491 4 PubMed abstract 11157797 5 PubMed abstract 15616553 6 PubMed abstract 7908405 7 PubMed abstract 8373420 8 PubMed abstract 8078491 9 PubMed abstract 11157797 10 PubMed abstract 15616553 |
Hormone | P61278 Detail in HMRbase |
Gene ID | 6755 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21045 |
Swiss-prot Accession number | P47798 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R) (BDF3). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Highly expressed in the testis. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis. |
Protein Length | 317 Amino acids |
Molecular weight | 34916 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8034052 2 PubMed abstract 8661706 3 PubMed abstract 10628296 4 Kriegesmann B., Brenig B., Dierkes B., Jansen S.; "A new melanocortin 1-receptor allele is coupled with Agouti coatcolour pattern in Holstein cattle."; Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 8034052 6 PubMed abstract 8661706 7 PubMed abstract 10628296 8 Kriegesmann B., Brenig B., Dierkes B., Jansen S.; "A new melanocortin 1-receptor allele is coupled with Agouti coatcolour pattern in Holstein cattle."; Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01190 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21051 |
Swiss-prot Accession number | P49660 (Sequence in FASTA format) |
Description | Somatostatin receptor type 4 (SS4R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. |
Protein Length | 384 Amino acids |
Molecular weight | 42090 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8654950 2 PubMed abstract 8654950 |
Hormone | P60041 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21052 |
Swiss-prot Accession number | P49683 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (hGR3). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Only detected in the pituitary gland and in all cell types of pituitary adenomas. |
Post translational modification | N/A |
Function | Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. |
Protein Length | 370 Amino acids |
Molecular weight | 41107 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8666380 2 PubMed abstract 9607765 3 PubMed abstract 11923475 4 PubMed abstract 15164054 5 PubMed abstract 15489334 6 PubMed abstract 10498338 7 PubMed abstract 11641419 8 PubMed abstract 8666380 9 PubMed abstract 9607765 10 PubMed abstract 11923475 11 PubMed abstract 15164054 12 PubMed abstract 15489334 13 PubMed abstract 10498338 14 PubMed abstract 11641419 |
Hormone | P81277 Detail in HMRbase |
Gene ID | 2834 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21053 |
Swiss-prot Accession number | P49922 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R)(Luteinizing hormone-releasing hormone receptor) (LHRH). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary gland. |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 328 Amino acids |
Molecular weight | 37747 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7928774 2 PubMed abstract 11269358 |
Hormone | P49921 Detail in HMRbase |
Gene ID | 397515 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21055 |
Swiss-prot Accession number | P52500 (Sequence in FASTA format) |
Description | Gastrin-releasing peptide receptor (GRP-R) (GRP-preferring bombesinreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gastrin releasing peptide (GRP). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 384 Amino acids |
Molecular weight | 43209 |
Domain Name | 7tm_1 |
References | 1 Wada E., Way J., Shapira H., Battey J.F.; "Two distinct bombesin receptor subtype subtypes in ppostnatal ratcentral nervous system."; Mol. Cell. Neurosci. 3:446-460(1992).
|
Hormone | P24393 Detail in HMRbase |
Gene ID | 24938 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21056 |
Swiss-prot Accession number | P56481 (Sequence in FASTA format) |
Description | Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR)(Cholecystokinin-2 receptor) (CCK2-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). |
Protein Length | 453 Amino acids |
Molecular weight | 49172 |
Domain Name | 7tm_1 |
References | 1 Kopin A.S.; Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 10860839 3 PubMed abstract 16141072 4 Kopin A.S.; Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 10860839 6 PubMed abstract 16141072 |
Hormone | P09240 Detail in HMRbase P48757 Detail in HMRbase |
Gene ID | 12426 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21058 |
Swiss-prot Accession number | P70031 (Sequence in FASTA format) |
Description | Cholecystokinin receptor (CCK-XLR). |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Brain and stomach. |
Post translational modification | N/A |
Function | Receptor for cholecystokinin. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Has high affinity for CCK-8 and low affinities for gastrin-17-I, CCK-4, and unsulfated CCK-8. |
Protein Length | 453 Amino acids |
Molecular weight | 51157 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8700154 2 PubMed abstract 8700154 |
Hormone | P50144 Detail in HMRbase P50145 Detail in HMRbase |
Gene ID | 378563 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21059 |
Swiss-prot Accession number | P70536 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 388 Amino acids |
Molecular weight | 42869 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7816817 2 Zingg H.H.; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 3 Terry R., Mullins D.; "Rat oxytocin receptor gene nucleotide sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 7816817 5 Zingg H.H.; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 6 Terry R., Mullins D.; "Rat oxytocin receptor gene nucleotide sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 7816817 8 Zingg H.H.; Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases. 9 Terry R., Mullins D.; "Rat oxytocin receptor gene nucleotide sequence."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01179 Detail in HMRbase |
Gene ID | 25342 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21061 |
Swiss-prot Accession number | P97639 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1) (Fragment). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | High level in the brain, moderate amounts in the eye and skeletal muscle, and small amounts in tongue and pituitary. |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to G proteins that inhibit adenylyl cyclase. |
Protein Length | 360 Amino acids |
Molecular weight | 39728 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9531978 2 PubMed abstract 8977118 3 PubMed abstract 10559938 4 PubMed abstract 10421368 |
Hormone | P14200 Detail in HMRbase |
Gene ID | 83567 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21062 |
Swiss-prot Accession number | P97926 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 388 Amino acids |
Molecular weight | 42752 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9027321 2 PubMed abstract 9027321 |
Hormone | P35454 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21063 |
Swiss-prot Accession number | Q01717 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 412 Amino acids |
Molecular weight | 46609 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1317787 2 PubMed abstract 1377915 3 PubMed abstract 8387312 4 PubMed abstract 1338727 5 PubMed abstract 8275956 6 PubMed abstract 7509436 7 PubMed abstract 1373613 8 PubMed abstract 1334485 |
Hormone | P01150 Detail in HMRbase |
Gene ID | 25570 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21064 |
Swiss-prot Accession number | Q01718 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Melanocytes and corticoadrenal tissue. |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. |
Protein Length | 297 Amino acids |
Molecular weight | 33927 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1325670 2 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 3 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15489334 5 PubMed abstract 8463333 6 PubMed abstract 15654338 7 Clark A.J.L., Weber A.; "Molecular insights into inherited ACTH resistance syndromes."; Trends Endocrinol. Metab. 5:209-214(1994). 8 PubMed abstract 8094489 9 PubMed abstract 8227361 10 PubMed abstract 8636348 11 PubMed abstract 10971458 12 PubMed abstract 12213892 13 PubMed abstract 1325670 14 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 15 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 16 PubMed abstract 15489334 17 PubMed abstract 8463333 18 PubMed abstract 15654338 19 Clark A.J.L., Weber A.; "Molecular insights into inherited ACTH resistance syndromes."; Trends Endocrinol. Metab. 5:209-214(1994). 20 PubMed abstract 8094489 21 PubMed abstract 8227361 22 PubMed abstract 8636348 23 PubMed abstract 10971458 24 PubMed abstract 12213892 25 PubMed abstract 1325670 26 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 27 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 28 PubMed abstract 15489334 29 PubMed abstract 8463333 30 PubMed abstract 15654338 31 Clark A.J.L., Weber A.; "Molecular insights into inherited ACTH resistance syndromes."; Trends Endocrinol. Metab. 5:209-214(1994). 32 PubMed abstract 8094489 33 PubMed abstract 8227361 34 PubMed abstract 8636348 35 PubMed abstract 10971458 36 PubMed abstract 12213892 |
Hormone | P01189 Detail in HMRbase |
Gene ID | 4158 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21065 |
Swiss-prot Accession number | Q01726 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Melanocytes and corticoadrenal tissue. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 317 Amino acids |
Molecular weight | 34706 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1325670 2 PubMed abstract 8463333 3 PubMed abstract 1516719 4 PubMed abstract 8706868 5 PubMed abstract 10101176 6 PubMed abstract 11442765 7 Smith A.G., Box N.F., Marks L., Chen W., Sturm R.A.; "Complete sequence and characterization of the human melanocortin 1receptor locus: a study of promoter region polymorphism."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. 8 PubMed abstract 11707265 9 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 10 Rieder M.J., Armel T.Z., Carrington D.P., Ozuna M., Kuldanek S.A.,Toth E.J., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. 11 PubMed abstract 15489334 12 PubMed abstract 9640562 13 PubMed abstract 7581459 14 PubMed abstract 8894704 15 PubMed abstract 9302268 16 PubMed abstract 8990005 17 PubMed abstract 9571181 18 PubMed abstract 9665397 19 PubMed abstract 1325670 20 PubMed abstract 8463333 21 PubMed abstract 1516719 22 PubMed abstract 8706868 23 PubMed abstract 10101176 24 PubMed abstract 11442765 25 Smith A.G., Box N.F., Marks L., Chen W., Sturm R.A.; "Complete sequence and characterization of the human melanocortin 1receptor locus: a study of promoter region polymorphism."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases. 26 PubMed abstract 11707265 27 Kopatz S.A., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. 28 Rieder M.J., Armel T.Z., Carrington D.P., Ozuna M., Kuldanek S.A.,Toth E.J., Yi Q., Nickerson D.A.; "SeattleSNPs. NHLBI HL66682 program for genomic applications, UW-FHCRC, Seattle, WA (URL: http://pga.gs.washington.edu)."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. 29 PubMed abstract 15489334 30 PubMed abstract 9640562 31 PubMed abstract 7581459 32 PubMed abstract 8894704 33 PubMed abstract 9302268 34 PubMed abstract 8990005 35 PubMed abstract 9571181 36 PubMed abstract 9665397 |
Hormone | P01189 Detail in HMRbase |
Gene ID | 4157 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21066 |
Swiss-prot Accession number | Q01727 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Melanocytes and corticoadrenal tissue. |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 315 Amino acids |
Molecular weight | 35282 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1325670 2 PubMed abstract 1325670 |
Hormone | P01193 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21067 |
Swiss-prot Accession number | Q01776 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Pituitary gland. |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 327 Amino acids |
Molecular weight | 37684 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1324422 2 PubMed abstract 1328228 3 Clay C.M., Nelson S.E., Campion C.E., Digregorio G.B.; Submitted (JUN-1994) to the EMBL/GenBank/DDBJ databases. |
Hormone | P13562 Detail in HMRbase Q99NF2 Detail in HMRbase |
Gene ID | 14715 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21082 |
Swiss-prot Accession number | Q28585 (Sequence in FASTA format) |
Description | Lutropin-choriogonadotropic hormone receptor (LH/CG-R) (LSH-R)(Luteinizing hormone receptor) (Fragment). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 6 LRR (leucine-rich) repeats. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. |
Protein Length | 538 Amino acids |
Molecular weight | 60232 |
Domain Name | 7tm_1 |
References | 1 Yarney T.A.; Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01218 Detail in HMRbase P01231 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21083 |
Swiss-prot Accession number | Q28596 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor (TRH-R) (Thyroliberinreceptor). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 398 Amino acids |
Molecular weight | 45089 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9048604 |
Hormone | P62969 Detail in HMRbase |
Gene ID | 443425 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21084 |
Swiss-prot Accession number | Q28756 (Sequence in FASTA format) |
Description | Oxytocin receptor (OT-R). |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol- calcium second messenger system. |
Protein Length | 391 Amino acids |
Molecular weight | 43271 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8800644 2 PubMed abstract 8691097 3 PubMed abstract 8800644 4 PubMed abstract 8691097 |
Hormone | P13389 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21085 |
Swiss-prot Accession number | Q2Q1V0 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 5b. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 301 Amino acids |
Molecular weight | 32527 |
Domain Name | 7tm_1 |
References | 1 Duran-Prado M., Delgado E., Luque R.M., Garcia-Navarro S.,Malagon M.M., Castano J.P.; Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21087 |
Swiss-prot Accession number | Q32XW9 (Sequence in FASTA format) |
Description | Ecdysis triggering hormone receptor subtype-A. |
Source organism | Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Sphingoidea;Sphingidae; Sphinginae; Manduca. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 573 Amino acids |
Molecular weight | 64945 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16968777 2 Kim Y.-J., Zitnan D., Cho K.-H., Adams M.E.; "Identification of Ecdysis Triggering Hormone Receptors in Manducasexta."; Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P11919 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21089 |
Swiss-prot Accession number | Q3ZB46 (Sequence in FASTA format) |
Description | Cholecystokinin B receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 453 Amino acids |
Molecular weight | 49172 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | P09240 Detail in HMRbase |
Gene ID | 12426 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21090 |
Swiss-prot Accession number | Q3ZB53 (Sequence in FASTA format) |
Description | Cholecystokinin B receptor. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 452 Amino acids |
Molecular weight | 49092 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12477932 2 Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | P09240 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21091 |
Swiss-prot Accession number | Q49LX5 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 (SS1R). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins (By similarity). |
Protein Length | 391 Amino acids |
Molecular weight | 42670 |
Domain Name | 7tm_1 |
References | 1 Liew C.W., Richter D., Kreienkamp H.-J.; "Cloning of somatostatin receptors from Canis familiaris."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
2 Liew C.W., Richter D., Kreienkamp H.-J.; "Cloning of somatostatin receptors from Canis familiaris."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P49670 Detail in HMRbase |
Gene ID | 403455 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21092 |
Swiss-prot Accession number | Q49LX6 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (SS2R). |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Cell membrane; multi-pass membrane protein (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels (By similarity). |
Protein Length | 369 Amino acids |
Molecular weight | 41293 |
Domain Name | 7tm_1 |
References | 1 Liew C.W., Richter D., Kreienkamp H.-J.; "Cloning of somatostatin receptors from Canis familiaris."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
2 Liew C.W., Richter D., Kreienkamp H.-J.; "Cloning of somatostatin receptors from Canis familiaris."; Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P49670 Detail in HMRbase |
Gene ID | 403472 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21094 |
Swiss-prot Accession number | Q4EW11 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10). |
Source organism | Bos taurus (Bovine) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing (By similarity). |
Protein Length | 370 Amino acids |
Molecular weight | 41226 |
Domain Name | 7tm_1 |
References | 1 Feng H., Yuan Z., Xiao S.D., Ying Y., Chun W.Y.; Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
2 Feng H., Yuan Z., Xiao S.D., Ying Y., Chun W.Y.; Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | P81264 Detail in HMRbase |
Gene ID | 510397 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21095 |
Swiss-prot Accession number | Q4PLA6 (Sequence in FASTA format) |
Description | Somatostatin receptor type 4. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 396 Amino acids |
Molecular weight | 43391 |
Domain Name | 7tm_1 |
References | 1 Li J., Hon C., Wang Y., Tam Y., Leung F.C.; "Molecular Characterization of Chicken Somatostatin Receptor Type 4(SS4R) Gene."; Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P33094 Detail in HMRbase |
Gene ID | 428547 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21096 |
Swiss-prot Accession number | Q4ZJF2 (Sequence in FASTA format) |
Description | Somatostatin receptor type 3. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 402 Amino acids |
Molecular weight | 44318 |
Domain Name | 7tm_1 |
References | 1 Li J., Hon C., Wang Y., Tse P., Leung F.C.; "Characterization of chicken somatostatin receptor type 3 (SS3R)gene."; Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P33094 Detail in HMRbase |
Gene ID | 427907 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21097 |
Swiss-prot Accession number | Q58G83 (Sequence in FASTA format) |
Description | Somatostatin receptor type 5. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 359 Amino acids |
Molecular weight | 40916 |
Domain Name | 7tm_1 |
References | 1 Li J., Hon C., Wang Y., So W., Leung F.C.; "Characterization of Chicken Somatostatin Receptor Type 5 (SS5R)."; Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P33094 Detail in HMRbase |
Gene ID | 427667 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21098 |
Swiss-prot Accession number | Q58G84 (Sequence in FASTA format) |
Description | Somatostatin receptor type 2 (Somatostatin receptor 2). |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 41583 |
Domain Name | 7tm_1 |
References | 1 Li J., Hon C., Wang Y., Wong C., Leung F.C.; "Characterization of Chicken Somatostatin Receptor Type 2 (SS2R)."; Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
2 Wang X.; "Molecular cloning of the chicken somatostatin receptor-2."; Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | P33094 Detail in HMRbase |
Gene ID | 395305 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21099 |
Swiss-prot Accession number | Q5EFE0 (Sequence in FASTA format) |
Description | Gonadotropin releasing hormone receptor 2. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 419 Amino acids |
Molecular weight | 45475 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16870947 |
Hormone | P37042 Detail in HMRbase P68072 Detail in HMRbase |
Gene ID | 427517 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21101 |
Swiss-prot Accession number | Q5G546 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 subtype B. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 41526 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14766000 |
Hormone | Q91194 Detail in HMRbase |
Gene ID | 100136672 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21102 |
Swiss-prot Accession number | Q5G547 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 subtype A. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 41734 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14766000 |
Hormone | Q91194 Detail in HMRbase |
Gene ID | 100136276 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21104 |
Swiss-prot Accession number | Q5TJK1 (Sequence in FASTA format) |
Description | Gonadotrophin releasing hormone receptor 1A. |
Source organism | Dicentrarchus labrax (European sea bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Dicentrarchus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 384 Amino acids |
Molecular weight | 42972 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15956346 |
Hormone | Q9IA08 Detail in HMRbase Q9IA09 Detail in HMRbase Q9IA10 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21105 |
Swiss-prot Accession number | Q5UKX6 (Sequence in FASTA format) |
Description | Gonadotropin releasing hormone type I receptor. |
Source organism | Haplochromis burtoni (Burton's mouthbrooder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini;Astatotilapia. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 421 Amino acids |
Molecular weight | 47547 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16440293 2 Illing N., Au T., Fernald R.; "Cichlid (Astatotilapia burtoni) gonadotropin releasing hormone type Ireceptor cDNA."; Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. |
Hormone | P51918 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21111 |
Swiss-prot Accession number | Q64121 (Sequence in FASTA format) |
Description | Prolactin-releasing peptide receptor (PrRP receptor) (PrRPR) (G-protein coupled receptor 10) (UHR-1). |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Widely expressed, with highest levels in pituitary, cerebellum, and hypothalamus. |
Post translational modification | N/A |
Function | Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. |
Protein Length | 370 Amino acids |
Molecular weight | 41161 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7733930 2 PubMed abstract 10498338 3 PubMed abstract 7733930 4 PubMed abstract 10498338 |
Hormone | P81278 Detail in HMRbase |
Gene ID | 246075 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21112 |
Swiss-prot Accession number | Q64326 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. |
Protein Length | 296 Amino acids |
Molecular weight | 33982 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7875603 2 PubMed abstract 7626130 3 PubMed abstract 7875603 4 PubMed abstract 7626130 |
Hormone | P01193 Detail in HMRbase |
Gene ID | 17200 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21113 |
Swiss-prot Accession number | Q683Z6 (Sequence in FASTA format) |
Description | Melanocortin-5 receptor. |
Source organism | Cyprinus carpio (Common carp) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 328 Amino acids |
Molecular weight | 37177 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15890786 |
Hormone | Q9YGK4 Detail in HMRbase Q9YGK5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21114 |
Swiss-prot Accession number | Q683Z7 (Sequence in FASTA format) |
Description | Melanocortin-5 receptor. |
Source organism | Cyprinus carpio (Common carp) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 328 Amino acids |
Molecular weight | 37163 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15890786 |
Hormone | Q9YGK4 Detail in HMRbase Q9YGK5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21115 |
Swiss-prot Accession number | Q6EWJ2 (Sequence in FASTA format) |
Description | Putative melanocortin-2 receptor. |
Source organism | Cyprinus carpio (Common carp) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Cyprinus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 304 Amino acids |
Molecular weight | 34347 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15890786 2 Metz J.; Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q9YGK4 Detail in HMRbase Q9YGK5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21117 |
Swiss-prot Accession number | Q6Q488 (Sequence in FASTA format) |
Description | Melanocortin 3 receptor. |
Source organism | Squalus acanthias (Spiny dogfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;Elasmobranchii; Squalea; Hypnosqualea; Squaliformes; Squaloidei;Squalidae; Squalus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 326 Amino acids |
Molecular weight | 37297 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 15511238 |
Hormone | P01197 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21118 |
Swiss-prot Accession number | Q6QLQ0 (Sequence in FASTA format) |
Description | Melanocortin 5 receptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 341 Amino acids |
Molecular weight | 38847 |
Domain Name | 7tm_1 |
References | 1 Haitina T., Klovins J., Andersson J., Fredriksson R., Lagerstrom M.C.,Larhammar D., Larson E.T., Schioth H.B.; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | Q04617 Detail in HMRbase Q04618 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21119 |
Swiss-prot Accession number | Q6QLQ1 (Sequence in FASTA format) |
Description | Melanocortin 4 receptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 339 Amino acids |
Molecular weight | 37572 |
Domain Name | 7tm_1 |
References | 1 Haitina T., Klovins J., Andersson J., Fredriksson R., Lagerstrom M.C.,Larhammar D., Larson E.T., Schioth H.B.; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
|
Hormone | Q04617 Detail in HMRbase Q04618 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21122 |
Swiss-prot Accession number | Q6YEX9 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 3. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 421 Amino acids |
Molecular weight | 45851 |
Domain Name | 7tm_1 |
References | 1 Duran-Prado M., Delgado E., Garcia-Navarro S., Castano J.P.,Malagon M.M.; "Sus scrofa somatostatin receptor subtype 3 mRNA."; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21123 |
Swiss-prot Accession number | Q6YEY1 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 5. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 40027 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16543371 |
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21124 |
Swiss-prot Accession number | Q71EB3 (Sequence in FASTA format) |
Description | Putative AKH receptor. |
Source organism | Drosophila melanogaster (Fruit fly) |
Taxonomical Classification | Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 455 Amino acids |
Molecular weight | 51437 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12177421 |
Hormone | P61855 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21125 |
Swiss-prot Accession number | Q76KC7 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 1. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 398 Amino acids |
Molecular weight | 44549 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14527724 |
Hormone | Q9DD49 Detail in HMRbase Q9DGC8 Detail in HMRbase Q9DGC9 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21126 |
Swiss-prot Accession number | Q76L92 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 3. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 394 Amino acids |
Molecular weight | 44408 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14527724 |
Hormone | Q9DD49 Detail in HMRbase Q9DGC8 Detail in HMRbase Q9DGC9 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21127 |
Swiss-prot Accession number | Q76L93 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 3. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 394 Amino acids |
Molecular weight | 44463 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14527724 |
Hormone | Q9DD49 Detail in HMRbase Q9DGC8 Detail in HMRbase Q9DGC9 Detail in HMRbase |
Gene ID | 100125529 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21129 |
Swiss-prot Accession number | Q7T2S8 (Sequence in FASTA format) |
Description | Type-three somatostatin receptor subtype B. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 452 Amino acids |
Molecular weight | 50776 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12576085 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21130 |
Swiss-prot Accession number | Q7T2S9 (Sequence in FASTA format) |
Description | Somatostatin receptor type five subtype C. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 377 Amino acids |
Molecular weight | 41898 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12576085 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21131 |
Swiss-prot Accession number | Q7TQP4 (Sequence in FASTA format) |
Description | Relaxin-3 receptor 2 (Relaxin family peptide receptor 4) (G-proteincoupled receptor 100). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Detected only in bone marrow. |
Post translational modification | N/A |
Function | Receptor for relaxin-3. Binding of the ligand inhibits cAMP accumulation (By similarity). |
Protein Length | 414 Amino acids |
Molecular weight | 45460 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14623098 2 PubMed abstract 12679517 |
Hormone | Q8CHK2 Detail in HMRbase |
Gene ID | 242093 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21132 |
Swiss-prot Accession number | Q7ZZJ9 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor type 1a variant. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 331 Amino acids |
Molecular weight | 37568 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14511992 |
Hormone | P41534 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21133 |
Swiss-prot Accession number | Q800V9 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 3. |
Source organism | Rana dybowskii (Dybovsky's frog) (Korean brown frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Rana. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 424 Amino acids |
Molecular weight | 47815 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12538604 |
Hormone | Q9IAU2 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21134 |
Swiss-prot Accession number | Q800W0 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 2. |
Source organism | Rana dybowskii (Dybovsky's frog) (Korean brown frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Rana. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 42103 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12538604 |
Hormone | Q9IAU2 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21135 |
Swiss-prot Accession number | Q864J8 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Macaca nemestrina (Pig-tailed macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase (By similarity). |
Protein Length | 317 Amino acids |
Molecular weight | 34783 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12687585 2 PubMed abstract 12687585 |
Hormone | P01201 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21136 |
Swiss-prot Accession number | Q866U3 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 1. |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 390 Amino acids |
Molecular weight | 42675 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16543371 2 Duran-Prado M., Delgado E., Garcia-Navarro S., Tostivint H.,Vaudry H., Malagon M.M., Castano J.P.; Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases. |
Hormone | P01168 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21137 |
Swiss-prot Accession number | Q8AXM7 (Sequence in FASTA format) |
Description | Type five somatostatin receptor subtype B. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 390 Amino acids |
Molecular weight | 43870 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12576085 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21139 |
Swiss-prot Accession number | Q8BGE9 (Sequence in FASTA format) |
Description | Relaxin-3 receptor 1 (RLN3 receptor 1) (Relaxin family peptidereceptor 3) (G protein-coupled receptor SALPR homolog). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for relaxin-3. Binding of the ligand inhibit cAMP accumulation (By similarity). |
Protein Length | 472 Amino acids |
Molecular weight | 51573 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16141072 2 PubMed abstract 15489334 |
Hormone | Q8CHK2 Detail in HMRbase |
Gene ID | 239336 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21140 |
Swiss-prot Accession number | Q8BKF6 (Sequence in FASTA format) |
Description | 0 day neonate eyeball cDNA, RIKEN full-length enriched library,clone:E130008P03 product:GASTRIN/CHOLECYSTOKININ TYPE B RECEPTOR, fullinsert sequence. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 453 Amino acids |
Molecular weight | 49144 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10349636 2 PubMed abstract 16141072 3 PubMed abstract 16141073 4 PubMed abstract 12466851 5 PubMed abstract 11217851 6 PubMed abstract 11042159 7 PubMed abstract 11076861 8 Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P.,Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W.,Hayashida K., Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T.,Hori F., Imotani K., Ishii Y., Itoh M., Kagawa I., Kasukawa T.,Katoh H., Kawai J., Kojima Y., Kondo S., Konno H., Kouda M., Koya S.,Kurihara C., Matsuyama T., Miyazaki A., Murata M., Nakamura M.,Nishi K., Nomura K., Numazaki R., Ohno M., Ohsato N., Okazaki Y.,Saito R., Saitoh H., Sakai C., Sakai K., Sakazume N., Sano H.,Sasaki D., Shibata K., Shinagawa A., Shiraki T., Sogabe Y., Tagami M.,Tagawa A., Takahashi F., Takaku-Akahira S., Takeda Y., Tanaka T.,Tomaru A., Toya T., Yasunishi A., Muramatsu M., Hayashizaki Y.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | P09240 Detail in HMRbase P48757 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21141 |
Swiss-prot Accession number | Q8CH60 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 328 Amino acids |
Molecular weight | 37690 |
Domain Name | 7tm_1 |
References | 1 Fujii Y., Ikemoto T., Park M.K.; "Molecular cloning of a GnRH receptor in the guinea pig."; Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
|
Hormone | O54713 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21143 |
Swiss-prot Accession number | Q8JFZ6 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 2. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 401 Amino acids |
Molecular weight | 45202 |
Domain Name | 7tm_1 |
References | 1 Bidaud I., Lory P., Bulant M., Montagne J.J., Nicolas P., Ladram A.; "Cloning and functional expression of amphibian cDNA encoding threenovel subtypes of Thyrotropin-Releasing Hormone receptor."; Eur. J. Biochem. 269:1-11(2002).
|
Hormone | P01152 Detail in HMRbase Q00643 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21144 |
Swiss-prot Accession number | Q8JID0 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 2. |
Source organism | Clarias gariepinus (Sharptooth catfish) (African catfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;Clariidae; Clarias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 375 Amino acids |
Molecular weight | 42676 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12446595 |
Hormone | P33439 Detail in HMRbase P43306 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21145 |
Swiss-prot Accession number | Q8JID5 (Sequence in FASTA format) |
Description | Somatostatin receptor type 3. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 477 Amino acids |
Molecular weight | 52878 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12576085 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21146 |
Swiss-prot Accession number | Q8JZL2 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. |
Protein Length | 423 Amino acids |
Molecular weight | 46269 |
Domain Name | 7tm_1 |
References | 1 Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 16141072 3 Lakaye B., Adamantidis A., Coumans B., Zorzi W., Parmentier M.,Grisar T.; "Cloning of the mouse melanin-concentrating hormone receptor 1 geneand promoter characterization."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 11471062 5 Ehringer M.A., Thompson J., Conroy O., Xu Y., Yang F., Canniff J.,Beeson M., Gordon L., Bennett B., Johnson T.E., Sikela J.M.; Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. |
Hormone | P56942 Detail in HMRbase |
Gene ID | 207911 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21147 |
Swiss-prot Accession number | Q8K3M8 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 alternate form. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 354 Amino acids |
Molecular weight | 39380 |
Domain Name | 7tm_1 |
References | 1 Lakaye B., Adamantidis A., Coumans B., Zorzi W., Parmentier M.,Grisar T.; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P56942 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21149 |
Swiss-prot Accession number | Q8MHZ5 (Sequence in FASTA format) |
Description | Ghrelin/growth hormone secretagogue receptor. |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 366 Amino acids |
Molecular weight | 41487 |
Domain Name | 7tm_1 |
References | 1 Murata T., Ikegami R., Morita Y., Shinozaki K.; "Sheep Ghrelin/Growth Hormone Secretagogue Receptor."; Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P07217 Detail in HMRbase |
Gene ID | 443238 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21150 |
Swiss-prot Accession number | Q8MI04 (Sequence in FASTA format) |
Description | Somatostatin receptor subtype 5. |
Source organism | Ovis aries (Sheep) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Caprinae; Ovis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 367 Amino acids |
Molecular weight | 40269 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12206873 2 Debus N.; "Regulation of GH secretion in sheep: Role of somatostatin and itsreceptors."; Thesis (1999), Department of Intercellular communications inEndocrinology, University of Aix-Marseilles II, Marseilles, France. |
Hormone | O46688 Detail in HMRbase |
Gene ID | 443210 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21151 |
Swiss-prot Accession number | Q8MIP5 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor subtype 2. |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 330 Amino acids |
Molecular weight | 37759 |
Domain Name | 7tm_1 |
References | 1 Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A., Hreniuk D.L.,Feighner S.D., Palyha O.C., Figueroa D.J., Austin C.P., Jiang M.M.,Yu H., Ito J., Ito M., Ito M., Guan X.M., Kanatani A.,Van der Ploeg L.H.T., Howard A.D.; "Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: SpeciesSpecific Gene Expression."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | Q5XXR2 Detail in HMRbase |
Gene ID | 403562 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21152 |
Swiss-prot Accession number | Q8MIP6 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor subtype 1. |
Source organism | Canis familiaris (Dog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 353 Amino acids |
Molecular weight | 39064 |
Domain Name | 7tm_1 |
References | 1 Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A., Hreniuk D.L.,Feighner S.D., Palyha O.C., Figueroa D.J., Austin C.P., Jiang M.M.,Yu H., Ito J., Ito M., Ito M., Guan X.M., Kanatani A.,Van der Ploeg L.H.T., Howard A.D.; "Melanin-Concentrating Hormone Receptor Subtypes 1 and 2: SpeciesSpecific Gene Expression."; Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
|
Hormone | Q5XXR2 Detail in HMRbase |
Gene ID | 403563 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21153 |
Swiss-prot Accession number | Q8QGQ4 (Sequence in FASTA format) |
Description | Type five-like somatostatin receptor. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 390 Amino acids |
Molecular weight | 44137 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12039069 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21157 |
Swiss-prot Accession number | Q8TDU9 (Sequence in FASTA format) |
Description | Relaxin-3 receptor 2 (Relaxin family peptide receptor 4) (G-proteincoupled receptor 100) (GPCR142). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in a broader range of tissues including brain, kidney, testis, thymus, placenta, prostate, salivary gland, thyroid and colon. |
Post translational modification | N/A |
Function | Receptor for relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation. |
Protein Length | 374 Amino acids |
Molecular weight | 41141 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14522967 2 PubMed abstract 14623098 3 PubMed abstract 14530218 4 Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S.,Tsutsumi S., Aburatani H., Asai K., Akiyama Y.; "Genome-wide discovery and analysis of human seven transmembrane helixreceptor genes."; Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. 5 PubMed abstract 12044878 6 PubMed abstract 16710414 7 PubMed abstract 15489334 |
Hormone | Q8WXF3 Detail in HMRbase |
Gene ID | 339403 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21158 |
Swiss-prot Accession number | Q8UUS1 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Dicentrarchus labrax (European sea bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Dicentrarchus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 416 Amino acids |
Molecular weight | 46996 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 14724132 |
Hormone | Q9IA08 Detail in HMRbase Q9IA09 Detail in HMRbase Q9IA10 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21161 |
Swiss-prot Accession number | Q90VY1 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 2. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 373 Amino acids |
Molecular weight | 42442 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11606438 |
Hormone | Q9DD49 Detail in HMRbase Q9DGC8 Detail in HMRbase Q9DGC9 Detail in HMRbase |
Gene ID | 100125528 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21162 |
Swiss-prot Accession number | Q90W00 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor 1. |
Source organism | Oryzias latipes (Medaka fish) (Japanese ricefish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Atherinomorpha;Beloniformes; Adrianichthyidae; Oryziinae; Oryzias. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 398 Amino acids |
Molecular weight | 44547 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11606438 |
Hormone | Q9DD49 Detail in HMRbase Q9DGC8 Detail in HMRbase Q9DGC9 Detail in HMRbase |
Gene ID | 100125422 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21163 |
Swiss-prot Accession number | Q90YM3 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Haplochromis burtoni (Burton's mouthbrooder) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Labroidei;Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini;Astatotilapia. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 388 Amino acids |
Molecular weight | 44326 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11316736 2 PubMed abstract 16440293 |
Hormone | P37044 Detail in HMRbase P45652 Detail in HMRbase P51918 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21168 |
Swiss-prot Accession number | Q95JG1 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
Source organism | Macaca mulatta (Rhesus macaque) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Length | 379 Amino acids |
Molecular weight | 41459 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11352653 |
Hormone | O97655 Detail in HMRbase |
Gene ID | 574163 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21170 |
Swiss-prot Accession number | Q969V1 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCHR-2)(MCH-R2) (MCH2R) (MCH-2R) (MCH2) (G-protein coupled receptor 145)(GPRv17). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Specifically expressed in the brain, with highest levels in cerebral cortex, hippocampus and amygdala. No expression detected in the cerebellum, thalamus or hypothalamus. |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. |
Protein Length | 340 Amino acids |
Molecular weight | 38849 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11355873 2 PubMed abstract 11404457 3 PubMed abstract 11459838 4 PubMed abstract 11274220 5 Kurama T., Matsumoto S., Takasaki J., Terai K., Matsumoto M.,Kamohara M., Saito T., Soga T., Saito Y., Oda T., Masuho Y.,Furuichi K.; "Molecular characterization of a novel melanin-concentrating hormonereceptor: evidence of its expression in lateral hypothalamus."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 6 King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 7 PubMed abstract 14574404 8 PubMed abstract 15489334 9 PubMed abstract 15340116 10 PubMed abstract 11355873 11 PubMed abstract 11404457 12 PubMed abstract 11459838 13 PubMed abstract 11274220 14 Kurama T., Matsumoto S., Takasaki J., Terai K., Matsumoto M.,Kamohara M., Saito T., Soga T., Saito Y., Oda T., Masuho Y.,Furuichi K.; "Molecular characterization of a novel melanin-concentrating hormonereceptor: evidence of its expression in lateral hypothalamus."; Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases. 15 King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 16 PubMed abstract 14574404 17 PubMed abstract 15489334 18 PubMed abstract 15340116 |
Hormone | P20382 Detail in HMRbase Q16048 Detail in HMRbase Q9BQD1 Detail in HMRbase |
Gene ID | 84539 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21171 |
Swiss-prot Accession number | Q96P88 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone II receptor (Type II GnRH receptor)(GnRH-II-R). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in many tissues. |
Post translational modification | Phosphorylated on the C-terminal cytoplasmic tail (Probable). |
Function | Receptor for gonadotropin releasing hormone II (GnRH II). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (Potential). |
Protein Length | 379 Amino acids |
Molecular weight | 41630 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11707068 2 PubMed abstract 11861490 |
Hormone | O43555 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21173 |
Swiss-prot Accession number | Q98T85 (Sequence in FASTA format) |
Description | Luteinizing hormone receptor precursor. |
Source organism | Ictalurus punctatus (Channel catfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;Ictaluridae; Ictalurus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 696 Amino acids |
Molecular weight | 77823 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11207219 2 Kumar R.S., Trant J.M.; Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q9YGP3 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21174 |
Swiss-prot Accession number | Q99705 (Sequence in FASTA format) |
Description | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCHR-1)(MCH-R1) (MCH1R) (MCH-1R) (MCHR) (G-protein coupled receptor 24)(Somatostatin receptor-like protein) (SLC-1). |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. |
Post translational modification | N/A |
Function | Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. |
Protein Length | 422 Amino acids |
Molecular weight | 45963 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10441476 2 PubMed abstract 15941924 3 Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S.,Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y.,Phelan M., Farmer A.; "Cloning of human full-length CDSs in BD Creator(TM) system donorvector."; Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 15461802 5 King M.M., Aronstam R.S., Sharma S.V.; "cDNA clones of human proteins involved in signal transductionsequenced by the Guthrie cDNA resource center (www.cdna.org)."; Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. 6 PubMed abstract 10591208 7 PubMed abstract 15489334 8 PubMed abstract 8977118 9 PubMed abstract 10421367 10 PubMed abstract 15166293 11 PubMed abstract 15340116 |
Hormone | P20382 Detail in HMRbase Q16048 Detail in HMRbase Q9BQD1 Detail in HMRbase |
Gene ID | 2847 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21175 |
Swiss-prot Accession number | Q99P50 (Sequence in FASTA format) |
Description | Growth hormone secretagogue receptor type 1 (GHS-R) (GH-releasingpeptide receptor) (GHRP) (Ghrelin receptor). |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine) (By similarity). |
Protein Length | 364 Amino acids |
Molecular weight | 40969 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 16141072 2 Kacsoh B.; "Cloning of mouse ghrelin/growth hormone secretagogue receptor cDNA byrapid amplification of cDNA ends (RACE)."; Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases. 3 Peng X., Frohman L.A., Kineman R.D.; Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q9EQX0 Detail in HMRbase |
Gene ID | 208188 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21179 |
Swiss-prot Accession number | Q9DDC9 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Gallus gallus (Chicken) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 375 Amino acids |
Molecular weight | 42097 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11112780 2 Sun Y.M.; Thesis (1998), Department of Chemincal Pathology, University of CapeTown, Cape Town, South Africa. |
Hormone | P37042 Detail in HMRbase P68072 Detail in HMRbase |
Gene ID | 395368 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21180 |
Swiss-prot Accession number | Q9DDR0 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 2. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 401 Amino acids |
Molecular weight | 45191 |
Domain Name | 7tm_1 |
References | 1 Dammann O., Harder S., Buck F., Richter D., Bruhn T.O.; "Differential Expression of Two Distinct Thyrotropin Releasing-HormoneReceptors Cloned from Xenopus laevis Brain."; Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01152 Detail in HMRbase Q00643 Detail in HMRbase |
Gene ID | 373632 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21181 |
Swiss-prot Accession number | Q9DDR1 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 1. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 397 Amino acids |
Molecular weight | 44971 |
Domain Name | 7tm_1 |
References | 1 Dammann O., Harder S., Buck F., Richter D., Bruhn T.O.; "Differential Expression of Two Distinct Thyrotropin Releasing-HormoneReceptors Cloned from Xenopus laevis Brain."; Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01152 Detail in HMRbase Q00643 Detail in HMRbase |
Gene ID | 373631 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21182 |
Swiss-prot Accession number | Q9DE60 (Sequence in FASTA format) |
Description | GnRH receptor-2. |
Source organism | Rana catesbeiana (Bull frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 371 Amino acids |
Molecular weight | 42018 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11120886 |
Hormone | Q90Y63 Detail in HMRbase Q9DG36 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21183 |
Swiss-prot Accession number | Q9DE62 (Sequence in FASTA format) |
Description | GnRH receptor-1. |
Source organism | Rana catesbeiana (Bull frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 407 Amino acids |
Molecular weight | 46054 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11120886 |
Hormone | Q90Y63 Detail in HMRbase Q9DG36 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21184 |
Swiss-prot Accession number | Q9DE63 (Sequence in FASTA format) |
Description | GnRH receptor-3 (Type III GnRHR). |
Source organism | Rana catesbeiana (Bull frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Aquarana. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 424 Amino acids |
Molecular weight | 47613 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11120886 2 PubMed abstract 11517181 |
Hormone | Q90Y63 Detail in HMRbase Q9DG36 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21185 |
Swiss-prot Accession number | Q9DGQ6 (Sequence in FASTA format) |
Description | Somatostatin receptor type two. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 380 Amino acids |
Molecular weight | 43146 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10996426 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21186 |
Swiss-prot Accession number | Q9ERT2 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 2. |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 382 Amino acids |
Molecular weight | 42051 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11181534 2 PubMed abstract 12477932 3 Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases. |
Hormone | Q62361 Detail in HMRbase |
Gene ID | 170732 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21188 |
Swiss-prot Accession number | Q9I8V4 (Sequence in FASTA format) |
Description | Gonadotropin releasing hormone receptor type I. |
Source organism | Xenopus laevis (African clawed frog) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 368 Amino acids |
Molecular weight | 41729 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10803587 |
Hormone | P45656 Detail in HMRbase |
Gene ID | 373765 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21189 |
Swiss-prot Accession number | Q9I986 (Sequence in FASTA format) |
Description | Gonadotropin-releasing hormone receptor. |
Source organism | Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 416 Amino acids |
Molecular weight | 47667 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11090458 |
Hormone | O42241 Detail in HMRbase P55246 Detail in HMRbase |
Gene ID | 100136028 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21190 |
Swiss-prot Accession number | Q9IA91 (Sequence in FASTA format) |
Description | Pituitary gonadotropin releasing hormone receptor. |
Source organism | Morone saxatilis (Striped bass) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei; Neoteleostei;Acanthomorpha; Acanthopterygii; Percomorpha; Perciformes; Percoidei;Moronidae; Morone. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 419 Amino acids |
Molecular weight | 47375 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 11064153 |
Hormone | O73811 Detail in HMRbase O73812 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21194 |
Swiss-prot Accession number | Q9PVF9 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 subtype B. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 367 Amino acids |
Molecular weight | 41614 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10537151 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21195 |
Swiss-prot Accession number | Q9PVG0 (Sequence in FASTA format) |
Description | Somatostatin receptor type 1 subtype A. |
Source organism | Carassius auratus (Goldfish) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 367 Amino acids |
Molecular weight | 41658 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10537151 |
Hormone | Q9YGH3 Detail in HMRbase Q9YGH4 Detail in HMRbase Q9YGH5 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21197 |
Swiss-prot Accession number | Q9R297 (Sequence in FASTA format) |
Description | Thyrotropin-releasing hormone receptor 2. |
Source organism | Rattus norvegicus (Rat) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Rattus. |
Subcellular location | Membrane; multi-pass membrane protein (By similarity). |
Developmental Stage | N/A |
Similarity | N/A |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 352 Amino acids |
Molecular weight | 39030 |
Domain Name | 7tm_1 |
References | 1 O'Dowd B.F., Lee D.K., Huang W., Nguyen T., Cheng R., Liu Y.,Gershengorn M.C., George S.R.; "TRH-R2 exhibits similar binding but distinct regulation and anatomicdistribution compared to TRH-R1."; Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
|
Hormone | P01150 Detail in HMRbase |
Gene ID | 252859 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21198 |
Swiss-prot Accession number | Q9TU05 (Sequence in FASTA format) |
Description | Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R). |
Source organism | Sus scrofa (Pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae;Sus. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a role in the regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis. |
Protein Length | 320 Amino acids |
Molecular weight | 34592 |
Domain Name | 7tm_1 |
References | 1 Cho I.C., Jung J.K., Jung Y.H., Jeon J.T.; "The complete sequence of pig (Sus scrofa) MC1R gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
2 PubMed abstract 9799269 3 Cho I.C., Jung J.K., Jung Y.H., Jeon J.T.; "The complete sequence of pig (Sus scrofa) MC1R gene."; Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases. 4 PubMed abstract 9799269 |
Hormone | P01192 Detail in HMRbase |
Gene ID | 494018 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21204 |
Swiss-prot Accession number | Q9Z1S9 (Sequence in FASTA format) |
Description | Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R)(Melanocortin receptor 2) (MC2-R) (Adrenocorticotropin receptor). |
Source organism | Cavia porcellus (Guinea pig) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;Hystricognathi; Caviidae; Cavia. |
Subcellular location | Membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. |
Protein Length | 297 Amino acids |
Molecular weight | 33715 |
Domain Name | 7tm_1 |
References | 1 Fang V.S., Juan C.-C., Lin Y.-S., Liu S.-T., Ho L.-T.; "Cloning of the guinea pig corticotropin (ACTH)-receptor gene."; Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
2 Fang V.S., Juan C.-C., Lin Y.-S., Liu S.-T., Ho L.-T.; "Cloning of the guinea pig corticotropin (ACTH)-receptor gene."; Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases. |
Hormone | P19402 Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21634 |
Swiss-prot Accession number | Q8TDS5 (Sequence in FASTA format) |
Description | Oxoeicosanoid receptor 1;Alternative Name: 5-oxo-ETE G-protein coupled receptor;Alternative Name: G-protein coupled receptor TG1019;Alternative Name: G-protein coupled receptor 170;Alternative Name: G-protein coupled receptor R527 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages. |
Post translational modification | N/A |
Function | Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. |
Protein Length | 423 Amino acids |
Molecular weight | 45811 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 12065583 2 PubMed abstract 12606753 3 PubMed abstract 12044878 4 PubMed abstract 15815621 5 PubMed abstract 15489334 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 165140 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21635 |
Swiss-prot Accession number | Q15722 (Sequence in FASTA format) |
Description | Leukotriene B4 receptor 1;LTB4-R 1;Alternative Name: P2Y purinoceptor 7;P2Y7;Alternative Name: Chemoattractant receptor-like 1;Alternative Name: G-protein coupled receptor 16 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues. |
Post translational modification | Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. |
Function | Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
Protein Length | 352 Amino acids |
Molecular weight | 37557 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8702478 2 PubMed abstract 8558062 3 PubMed abstract 9177352 4 PubMed abstract 8921391 5 PubMed abstract 10934229 6 PubMed abstract 15489334 7 PubMed abstract 12077128 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 1241 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21636 |
Swiss-prot Accession number | Q9Y271 (Sequence in FASTA format) |
Description | Cysteinyl leukotriene receptor 1;CysLTR1;Alternative Name: Cysteinyl leukotriene D4 receptor;LTD4 receptor;Alternative Name: HG55;Alternative Name: HMTMF81 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart. |
Post translational modification | N/A |
Function | Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. |
Protein Length | 337 Amino acids |
Molecular weight | 38541 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10391245 2 PubMed abstract 10462554 3 PubMed abstract 15772651 4 PubMed abstract 15489334 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 10800 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21637 |
Swiss-prot Accession number | Q9NPC1 (Sequence in FASTA format) |
Description | Leukotriene B4 receptor 2;LTB4-R2;Alternative Name: Seven transmembrane receptor BLTR2;Alternative Name: Leukotriene B4 receptor BLT2;Alternative Name: LTB4 receptor JULF2 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Widely expressed. |
Post translational modification | N/A |
Function | Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. |
Protein Length | 389 Amino acids |
Molecular weight | 41525 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10913346 2 PubMed abstract 10934230 3 PubMed abstract 11006272 4 PubMed abstract 10889186 5 PubMed abstract 12044878 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 56413 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21638 |
Swiss-prot Accession number | Q9NS75 (Sequence in FASTA format) |
Description | Cysteinyl leukotriene receptor 2;CysLTR2;Alternative Name: HG57;Alternative Name: HPN321;Alternative Name: hGPCR21 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells. |
Post translational modification | N/A |
Function | Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. |
Protein Length | 346 Amino acids |
Molecular weight | 39635 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 10913337 2 PubMed abstract 10851239 3 PubMed abstract 11093801 4 PubMed abstract 12044878 5 PubMed abstract 15057823 6 PubMed abstract 15489334 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | 57105 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21639 |
Swiss-prot Accession number | P25090 (Sequence in FASTA format) |
Description | N-formyl peptide receptor 2;Alternative Name: FMLP-related receptor I;FMLP-R-I;Alternative Name: Formyl peptide receptor-like 1;Alternative Name: Lipoxin A4 receptor;LXA4 receptor;Alternative Name: RFP;Alternative Name: HM63 |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis. |
Post translational modification | N/A |
Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). |
Protein Length | 351 Amino acids |
Molecular weight | 38964 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1612600 2 PubMed abstract 1511907 3 PubMed abstract 1374236 4 PubMed abstract 1373134 5 PubMed abstract 7505609 6 PubMed abstract 9547339 7 PubMed abstract 15057824 8 PubMed abstract 15489334 9 PubMed abstract 9151906 |
Hormone | Detail in HMRbase |
Gene ID | 2358 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21640 |
Swiss-prot Accession number | P43119 (Sequence in FASTA format) |
Description | Prostacyclin receptor;Alternative Name: Prostanoid IP receptor;Alternative Name: PGI receptor;Alternative Name: Prostaglandin I2 receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling. Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C. |
Function | Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase. |
Protein Length | 386 Amino acids |
Molecular weight | 40956 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7512962 2 PubMed abstract 7514139 3 PubMed abstract 7923647 4 PubMed abstract 7665161 5 PubMed abstract 15489334 6 PubMed abstract 11895442 7 PubMed abstract 12488443 8 PubMed abstract 15194446 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 5739 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21641 |
Swiss-prot Accession number | Q13258 (Sequence in FASTA format) |
Description | Prostaglandin D2 receptor;Alternative Name: Prostanoid DP receptor;Alternative Name: PGD receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in retina and small intestine. |
Post translational modification | N/A |
Function | Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. |
Protein Length | 359 Amino acids |
Molecular weight | 40271 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7642548 2 PubMed abstract 15489334 3 PubMed abstract 15496624 |
Hormone | Detail in HMRbase |
Gene ID | 5729 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21642 |
Swiss-prot Accession number | P34995 (Sequence in FASTA format) |
Description | Prostaglandin E2 receptor EP1 subtype;Alternative Name: Prostanoid EP1 receptor;Alternative Name: PGE receptor, EP1 subtype |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart. |
Post translational modification | Phosphorylated (Potential). |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. |
Protein Length | 402 Amino acids |
Molecular weight | 41801 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8253813 2 PubMed abstract 15489334 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 5731 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21643 |
Swiss-prot Accession number | P43116 (Sequence in FASTA format) |
Description | Prostaglandin E2 receptor EP2 subtype;Alternative Name: Prostanoid EP2 receptor;Alternative Name: PGE receptor, EP2 subtype |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Placenta and lung. |
Post translational modification | N/A |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. |
Protein Length | 358 Amino acids |
Molecular weight | 39761 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8078484 2 PubMed abstract 10521663 3 PubMed abstract 15489334 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 5732 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21644 |
Swiss-prot Accession number | P43115 (Sequence in FASTA format) |
Description | Prostaglandin E2 receptor EP3 subtype;PGE receptor, EP3 subtype;PGE2-R;Alternative Name: Prostanoid EP3 receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels. |
Post translational modification | N/A |
Function | Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity). |
Protein Length | 390 Amino acids |
Molecular weight | 43310 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8307176 2 PubMed abstract 7883006 3 PubMed abstract 8117308 4 PubMed abstract 8135729 5 PubMed abstract 7981210 6 PubMed abstract 7476918 7 PubMed abstract 8075855 8 PubMed abstract 9073510 9 PubMed abstract 16710414 10 PubMed abstract 15489334 11 PubMed abstract 18023986 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 5733 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21645 |
Swiss-prot Accession number | P35408 (Sequence in FASTA format) |
Description | Prostaglandin E2 receptor EP4 subtype;PGE receptor, EP4 subtype;Alternative Name: Prostanoid EP4 receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. |
Post translational modification | N/A |
Function | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. |
Protein Length | 488 Amino acids |
Molecular weight | 53119 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8163486 2 PubMed abstract 8250933 3 PubMed abstract 8661119 4 PubMed abstract 8862514 5 PubMed abstract 15489334 6 PubMed abstract 16424369 |
Hormone | Detail in HMRbase Detail in HMRbase |
Gene ID | 5734 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21646 |
Swiss-prot Accession number | P43088 (Sequence in FASTA format) |
Description | Prostaglandin F2-alpha receptor;PGF2 alpha receptor;Alternative Name: Prostanoid FP receptor;Alternative Name: PGF receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). |
Protein Length | 359 Amino acids |
Molecular weight | 40055 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8300593 2 PubMed abstract 9341156 3 PubMed abstract 14702039 4 PubMed abstract 16710414 5 PubMed abstract 15489334 |
Hormone | Detail in HMRbase |
Gene ID | 5737 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |
HMRbase accession number | 21647 |
Swiss-prot Accession number | P21731 (Sequence in FASTA format) |
Description | Thromboxane A2 receptor;TXA2-R;Alternative Name: Prostanoid TP receptor |
Source organism | Homo sapiens (Human) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo. |
Subcellular location | Cell membrane; Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. |
Protein Length | 369 Amino acids |
Molecular weight | 40092 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 1825698 2 PubMed abstract 8034687 3 PubMed abstract 7896853 4 PubMed abstract 7965765 5 PubMed abstract 8227091 6 PubMed abstract 15057824 7 PubMed abstract 15489334 8 PubMed abstract 8246916 9 PubMed abstract 7929844 |
Hormone | Detail in HMRbase |
Gene ID | N/A |
PDB ID | 1LBN |
Drugpedia | wiki |
Comments |
HMRbase accession number | 22952 |
Swiss-prot Accession number | P47936 (Sequence in FASTA format) |
Description | Cannabinoid receptor 2;CB-2;CB2 |
Source organism | Mus musculus (Mouse) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata;Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires;Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus. |
Subcellular location | Cell membrane;Multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Involved in cannabinoid-induced CNS effects through G- protein mediated inhibition of adenylate cyclase. Could be a receptor for anandamide. |
Protein Length | 347 Amino acids |
Molecular weight | 38213 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 8679694 2 PubMed abstract 9261404 3 PubMed abstract 15489334 |
Hormone | Detail in HMRbase |
Gene ID | 12802 |
PDB ID | N/A |
Drugpedia | wiki |
Comments |