Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Predicted Immune Epitope Results


The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


NeoepitopesVQRDDVRQI        Click here to BLAST against human proteome
CTL Epitope
(CTLPred)
Y
HLA I Alleles
(ProPred I)
HLA-B*2702, HLA-B*3501, HLA-B*51, HLA-B*5101, HLA-B62, HLA-B7, MHC-Kk7
HLA I Alleles
(nHLAPred)
HLA-B27, HLA-B*2705, HLA-Cw*0401, H2-Db, H2-Dd, H2-Kb, H2-Kd, H2-Ld, HLA-G, H-2Qa, Mamu-A*0111
HLA II Alleles
(PrePred)
DRB1_0301, DRB1_0305, DRB1_0306, DRB1_0307, DRB1_0308, DRB1_0309, DRB1_0311, DRB1_0401, DRB1_0402, DRB1_0421, DRB1_0426, DRB1_1102, DRB1_1107, DRB1_1114, DRB1_1120, DRB1_1121, DRB1_1301, DRB1_1302, DRB1_1304, DRB1_1322, DRB1_1323, DRB1_1327, DRB1_132823
B_Cell_Epitope
(ABCPred)
N

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