Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Vaccine target/antigen submission

In this tool user has to provide a mutated protein sequence of cancer patient/cell line. On comparision with the human proteome with given target of our database, we will identify the cancer specific mutation and possible immune epitopes for the patient/cell line. For more information click HERE.

Paste a mutated target protein sequence from cancer sample, in FASTA format

OR
Upload Sequence file

Select corresponding target protein from list below

Select any one of the Targets

AAK1 ABL1 AKAP12 AKAP9 ALK
ALPK2 ATM BRAF CARD10 CBL
CDH1 CHD1 CREB3L2 CTBP2 CTNNB1
EGFR ERBB2 FBXW7 FGFR2 FGFR3
FLT3 FMN2 GATA1 GPR112 HSP90B1
JAK2 KIT MAML2 MAP3K1 MAP3K4
MEN1 MET MLH1 MLL3 MSH2
MSH3 MSH6 MYLK MYST4 NCOA3
NF1 NF2 NR1H2 NRAS PDE4DIP
PDGFRA PIK3C2G PIK3CA PRKDC PTEN
RB1 RECQL4 RET SMAD4 TNFAIP3
TNRC6B TP53 TSHR TTBK1 VHL

Select Epitope Types to be Displayed:

MHC-I Binders MHC-II Binders Cytotoxic T-Cell Epitopes Linear B-Cell Epitopes All