Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Predicted Immune Epitope Results


The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


NeoepitopesSAPLALSSL        Click here to BLAST against human proteome
CTL Epitope
(CTLPred)
Y
HLA I Alleles
(ProPred I)
HLA-B14, HLA-B*3501, HLA-B*3902, HLA-B*5101, HLA-B*5102, HLA-B*5103, HLA-B*5801, HLA-B60, HLA-B7, HLA-B8, HLA-Cw*0401, MHC-Db, MHC-Db revised, MHC-Dd, MHC-Kb15
HLA I Alleles
(nHLAPred)
HLA-B*3501, HLA-Cw*0401, H2-Db, H2-Dd, H2-Kb, H2-Kd, H2-Ld, HLA-G, H-2Qa, Mamu-A*0110
HLA II Alleles
(PrePred)
NA0
B_Cell_Epitope
(ABCPred)
N

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package