Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0025 | Mannan Click for more detail | Fungi | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8416946 | 1993 | NA |
| PRRID_0025 | Mannan Click for more detail | Fungi | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Immunostimulant | Mannose receptor | Mannose receptor (MR) | NA | NA | NA | NA | NA | NA | NA | ELISA | 8416946 | 1993 | NA |
| PRRID_0134 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0134 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0135 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This is responsible for the anti-fungal response of the host immune system. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0135 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This is responsible for the anti-fungal response of the host immune system. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0136 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0136 | Mannan Click for more detail | S. cerevisiae (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This leads to the inflammatory response. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0137 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This is responsible for the anti-fungal response of the host immune system. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0137 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Monocytes | NA | O00206.fasta | O00206 | 839 | This is responsible for the anti-fungal response of the host immune system. | ELISA | 12222939 | 2002 | Pubchem Assay |
| PRRID_0671 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | dendritic cells and macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 20713100 | 2010 | Pubchem Assay |
| PRRID_0671 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | dendritic cells and macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 20713100 | 2010 | Pubchem Assay |
| PRRID_0672 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Cell surface | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | It leadsto the secretion of the proinfalmmatory cytokines and IFN-β | NA | 20620129 | 2010 | Pubchem Assay |
| PRRID_0672 | Mannan Click for more detail | Candida albicans(fungi) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Cell surface | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | It leadsto the secretion of the proinfalmmatory cytokines and IFN-β | NA | 20620129 | 2010 | Pubchem Assay |
| PRRID_0673 | Mannan Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | It is the responsive PAMP for the FcLec5 | FcLec5 | C type Lectin (CTL/CLR) | Fenneropenaeus chinensis | hepatopancreas | CRD | NA | NA | NA | It elicit the immune response, which leads to the clearance of bacteria | ELISA | 20349323 | 2010 | NA |
| PRRID_0673 | Mannan Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | It is the responsive PAMP for the FcLec5 | FcLec5 | C type Lectin (CTL/CLR) | Fenneropenaeus chinensis | hepatopancreas | CRD | NA | NA | NA | It elicit the immune response, which leads to the clearance of bacteria | ELISA | 20349323 | 2010 | NA |
| PRRID_1106 | Mannan Click for more detail | S. cerevisiae (Bacteria) | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O | NA | Polysaccharides | Natural | PPL is a glycoprotein with a mannan-binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1106 | Mannan Click for more detail | S. cerevisiae (Bacteria) | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O | NA | Polysaccharides | Natural | PPL is a glycoprotein with a mannan-binding specificity and elicits the downstream cascade. | Philyra pisum lectin (PPL) | Mannose receptor (MR) | Philyra pisum | NA | NA | NA | NA | NA | It has antiproliferative effects on human cancer cells | Hemagglutination inhibition assay | 24381505 | 2013 | NA |
| PRRID_1482 | Mannan Click for more detail | Fungi(Yeast) | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Polysaccharides | Natural | cell wall polysaccharide found in yeasts. | Mannose receptor | Mannose receptor (MR) | European and African Children | DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) | NA | A5D8T8.fasta | A5D8T8 | 446 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | ELISA | 24743542 | 2014 | Pubchem_assay |
| PRRID_1482 | Mannan Click for more detail | Fungi(Yeast) | N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O | NA | Polysaccharides | Natural | cell wall polysaccharide found in yeasts. | Mannose receptor | Mannose receptor (MR) | European and African Children | DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin) | NA | A5D8T8.fasta | A5D8T8 | 446 | Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation | ELISA | 24743542 | 2014 | Pubchem_assay |
| PRRID_1785 | Mannan Click for more detail | Gram-negative bacteria Escherichia coli, Vibrio anguillarum | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Bacterial infection and immunostimulant | CgPGRPS2 | Peptidoglycan Recognition Receptor (PGRPs) | Crassostrea gigas | Cytoplasm | one typical PGRP/amidase domain | NA | NA | NA | Activate NF-kB | PAMPs binding assay | 28042081 | 2016 | NA |
| PRRID_1785 | Mannan Click for more detail | Gram-negative bacteria Escherichia coli, Vibrio anguillarum | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Bacterial infection and immunostimulant | CgPGRPS2 | Peptidoglycan Recognition Receptor (PGRPs) | Crassostrea gigas | Cytoplasm | one typical PGRP/amidase domain | NA | NA | NA | Activate NF-kB | PAMPs binding assay | 28042081 | 2016 | NA |
| PRRID_1788 | Mannan Click for more detail | Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Bacterial infection and immunostimulant | CgPGRPS2 | Peptidoglycan Recognition Receptor (PGRPs) | Crassostrea gigas | Cytoplasm | one typical PGRP/amidase domain | NA | NA | NA | Activate NF-kB | PAMPs binding assay | 28042081 | 2016 | NA |
| PRRID_1788 | Mannan Click for more detail | Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Bacterial infection and immunostimulant | CgPGRPS2 | Peptidoglycan Recognition Receptor (PGRPs) | Crassostrea gigas | Cytoplasm | one typical PGRP/amidase domain | NA | NA | NA | Activate NF-kB | PAMPs binding assay | 28042081 | 2016 | NA |
| PRRID_1801 | Mannan Click for more detail | S. cerevisiae (Bacteria) | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O | NA | Polysaccharides | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | Activate NF-Kb | NA | 27293318 | 2016 | NA |
| PRRID_1801 | Mannan Click for more detail | S. cerevisiae (Bacteria) | C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O | NA | Polysaccharides | Natural | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | Activate NF-Kb | NA | 27293318 | 2016 | NA |
| PRRID_2303 | Mannan Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | NA | rCgPGRPS2 | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 28042081 | 2017 | NA |
| PRRID_2303 | Mannan Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | NA | rCgPGRPS2 | Pattern recognition receptor (PRR) | NA | NA | NA | NA | NA | NA | NA | NA | 28042081 | 2017 | NA |
| PRRID_2323 | Mannan Click for more detail | Fungi(Yeast) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Activate macrophages and produce inflammatory responses, Induce NF-κB activation, induce PGE2, IL-1β, and TNF-α production, by macrophages | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2323 | Mannan Click for more detail | Fungi(Yeast) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Activate macrophages and produce inflammatory responses, Induce NF-κB activation, induce PGE2, IL-1β, and TNF-α production, by macrophages | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | NA | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2324 | Mannan Click for more detail | Fungi(Yeast) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Activate macrophages and produce inflammatory responses, Induce NF-κB activation, induce PGE2, IL-1β, and TNF-α production, by macrophages | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29028369 | 2017 | Pubchem_assay |
| PRRID_2324 | Mannan Click for more detail | Fungi(Yeast) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Polysaccharides | Natural | Activate macrophages and produce inflammatory responses, Induce NF-κB activation, induce PGE2, IL-1β, and TNF-α production, by macrophages | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | NA | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | NA | NA | 29028369 | 2017 | Pubchem_assay |