Detailed description page of PRRDB2.0

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PRRID_0672 details
Primary information
PRRIDPRRID_0672
Ligand NameMannan
SourceCandida albicans(fungi)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypePolysaccharides
OccurenceNatural
Role of LigandUpon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationCell surface
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt leadsto the secretion of the proinfalmmatory cytokines and IFN-β
Assay usedNA
PMID20620129
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0672
Ligand NameMannan
SourceCandida albicans(fungi)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypePolysaccharides
OccurenceNatural
Role of LigandUpon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationCell surface
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt leadsto the secretion of the proinfalmmatory cytokines and IFN-β
Assay usedNA
PMID20620129
Year of Publication2010
Pubchem assayPubchem Assay