Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_0007 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Chinese Hamster | Chinese hamster ovary fibroblasts | NA | NA | NA | NA | NA | NA | 2473841 | 1989 | NA |
| PRRID_0007 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | Immunostimulant | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Chinese Hamster | Chinese hamster ovary fibroblasts | NA | NA | NA | NA | NA | NA | 2473841 | 1989 | NA |
| PRRID_0082 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Raw 264.7 cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0082 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Raw 264.7 cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0083 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | U373 human astrocytoma cells | LRR | O00206.fasta | O00206 | 839 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0083 | ER-112022 Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Synthetic | It activated the NF-KB pathway and resulted into the secretion of TNF-alpha and IL-6. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | U373 human astrocytoma cells | LRR | O00206.fasta | O00206 | 839 | It has the role in immuno inflammation. | ELISA | 11032843 | 2000 | Pubchem Assay |
| PRRID_0139 | MPL A (monophosphoryl lipid A) Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Natural | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0139 | MPL A (monophosphoryl lipid A) Click for more detail | lipid A derivative (others) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Natural | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0145 | RC-528 Click for more detail | lipid A derivative (others) | NA | NA | Lipid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0145 | RC-528 Click for more detail | lipid A derivative (others) | NA | NA | Lipid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0146 | RC529 Click for more detail | lipid A derivative (others) | NA | NA | Lipid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0146 | RC529 Click for more detail | lipid A derivative (others) | NA | NA | Lipid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0147 | RC544 Click for more detail | lipid A derivative (others) | NA | NA | Lipid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0147 | RC544 Click for more detail | lipid A derivative (others) | NA | NA | Lipid | Synthetic | induce systemic production of pro-inflammatory cytokines | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | NA | NA | 12377566 | 2002 | NA |
| PRRID_0247 | MPL (Monophosphoryl-lipid A/trehalose dicorynomycolate (“Ribi” adjuvant)) Click for more detail | lipid A mimetic (others) | CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(=O)(O)O)OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O)O | NA | Lipid | Synthetic | Immunostimulant | Toll-like receptor 4+unknown | Toll-like receptor (TLR) | Mice | NA | NA | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 17185603 | 2006 | Pubchem Assay |
| PRRID_0247 | MPL (Monophosphoryl-lipid A/trehalose dicorynomycolate (“Ribi” adjuvant)) Click for more detail | lipid A mimetic (others) | CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(=O)(O)O)OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O)O | NA | Lipid | Synthetic | Immunostimulant | Toll-like receptor 4+unknown | Toll-like receptor (TLR) | Mice | NA | NA | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 17185603 | 2006 | Pubchem Assay |
| PRRID_0272 | Aminoalkyl Glucosaminide Phosphate (AGP) Click for more detail | NA | NA | NA | Lipid | Synthetic | AGPs boost the innate immune response to infection with F. novicida. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macropahges and Dendritic cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It provides Protectection to Mice from Pneumonic Tularemia. | ELISA | 18490759 | 2008 | Pubchem Assay |
| PRRID_0272 | Aminoalkyl Glucosaminide Phosphate (AGP) Click for more detail | NA | NA | NA | Lipid | Synthetic | AGPs boost the innate immune response to infection with F. novicida. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice | Macropahges and Dendritic cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It provides Protectection to Mice from Pneumonic Tularemia. | ELISA | 18490759 | 2008 | Pubchem Assay |
| PRRID_0301 | Lipid A Click for more detail | Burkholderia pseudomallei(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Natural | Stimulation via LPS leads to the production of TNF-α, MIP-2, and IL-10. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | HEK293 cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has a immunostimulatory role | ELISA | 18691413 | 2008 | Pubchem Assay |
| PRRID_0301 | Lipid A Click for more detail | Burkholderia pseudomallei(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Natural | Stimulation via LPS leads to the production of TNF-α, MIP-2, and IL-10. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | HEK293 cells | LRR | Q9QUK6.fasta | Q9QUK6 | 835 | It has a immunostimulatory role | ELISA | 18691413 | 2008 | Pubchem Assay |
| PRRID_0302 | Lipid A Click for more detail | Burkholderia pseudomallei(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Natural | Stimulation via LPS leads to the activation of NF-KappaB, which resulted into the production of TNF-α, MIP-2, and IL-10. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | HEK293 cells | LRR | O00206.fasta | O00206 | 839 | It has a immunostimulatory role | ELISA | 18691413 | 2008 | Pubchem Assay |
| PRRID_0302 | Lipid A Click for more detail | Burkholderia pseudomallei(Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipid | Natural | Stimulation via LPS leads to the activation of NF-KappaB, which resulted into the production of TNF-α, MIP-2, and IL-10. | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | HEK293 cells | LRR | O00206.fasta | O00206 | 839 | It has a immunostimulatory role | ELISA | 18691413 | 2008 | Pubchem Assay |
| PRRID_0535 | Glycoinositol phospholipids Click for more detail | Trypanosoma (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | dendritic cells and macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 20713100 | 2010 | Pubchem Assay |
| PRRID_0535 | Glycoinositol phospholipids Click for more detail | Trypanosoma (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | NA | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Mice (Murine) | dendritic cells and macrophages | Leucine-rich Repeat (LRR) Domain | Q9QUK6.fasta | Q9QUK6 | 835 | NA | NA | 20713100 | 2010 | Pubchem Assay |
| PRRID_0536 | Glycoinositol phospholipids Click for more detail | Trypanosoma (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Cell surface | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | It leadsto the secretion of the proinfalmmatory cytokines and IFN-β | NA | 20620129 | 2010 | Pubchem Assay |
| PRRID_0536 | Glycoinositol phospholipids Click for more detail | Trypanosoma (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF | Toll-like receptor 4 (TLR4) | Toll-like receptor (TLR) | Human | Cell surface | Leucine-rich Repeat (LRR) Domain | O00206.fasta | O00206 | 839 | It leadsto the secretion of the proinfalmmatory cytokines and IFN-β | NA | 20620129 | 2010 | Pubchem Assay |
| PRRID_0718 | OM-174 Click for more detail | E. coli(Bacteria) | CCCCCCCCCCC[C@@H](O)CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]2NC(=O)C[C@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@@H]1OP(O)(O)=O | NA | Lipid | Natural | it induce the expression of iNOS, tumour suppressive proteins and cytokines | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | Liver | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It results into inhibition of invasion and metastasis of HCC | NA | 20675699 | 2010 | NA |
| PRRID_0718 | OM-174 Click for more detail | E. coli(Bacteria) | CCCCCCCCCCC[C@@H](O)CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]2NC(=O)C[C@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O[C@@H]1OP(O)(O)=O | NA | Lipid | Natural | it induce the expression of iNOS, tumour suppressive proteins and cytokines | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Rat | Liver | Leucine-rich Repeat (LRR) Domain | NA | NA | NA | It results into inhibition of invasion and metastasis of HCC | NA | 20675699 | 2010 | NA |
| PRRID_0870 | Atypic lipopolysaccharides Click for more detail | Leptospira interrogans (Bacteria) | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0870 | Atypic lipopolysaccharides Click for more detail | Leptospira interrogans (Bacteria) | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0876 | Diacylated Lipopeptide Click for more detail | Mycoplasma, Gram-positive bacteria | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Myeloid cells, dendritic cells, microglia, astrocytes | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | significant role in the pathogenesis of severe inflammatory responses | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0876 | Diacylated Lipopeptide Click for more detail | Mycoplasma, Gram-positive bacteria | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | Human | Myeloid cells, dendritic cells, microglia, astrocytes | NA | Q9Y2C9.fasta | Q9Y2C9 | 796 | significant role in the pathogenesis of severe inflammatory responses | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0877 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0877 | Diacylated Lipopeptide Click for more detail | Mycoplasma (Bacteria) | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 6 (TLR6) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0892 | Glycoinositol phospholipids Click for more detail | eukaryotic cell membranes (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | triggers immune responses | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0892 | Glycoinositol phospholipids Click for more detail | eukaryotic cell membranes (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | triggers immune responses | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0893 | Glycoinositol phospholipids Click for more detail | Trypanosoma Cruzi (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | triggers immune responses | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0893 | Glycoinositol phospholipids Click for more detail | Trypanosoma Cruzi (others) | C(C(COP(=O)(O)OC1C(C(C(C(C1O)O)O)O)O)OC=O)OC=O | NA | Lipid | Natural | triggers immune responses | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21955443 | 2011 | NA |
| PRRID_0894 | Glycolipids Click for more detail | eukaryotic cell membranes (others) | NA | NA | Lipid | Natural | Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0894 | Glycolipids Click for more detail | eukaryotic cell membranes (others) | NA | NA | Lipid | Natural | Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0895 | Glycolipids Click for more detail | Treponema maltophilum (others) | NA | NA | Lipid | Natural | Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21955443 | 2011 | NA |
| PRRID_0895 | Glycolipids Click for more detail | Treponema maltophilum (others) | NA | NA | Lipid | Natural | Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21955443 | 2011 | NA |
| PRRID_0925 | lipoprotein or lipopeptides Click for more detail | Gram-positive bacteria | NA | NA | Lipid | Synthetic | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21949866 | 2011 | NA |
| PRRID_0925 | lipoprotein or lipopeptides Click for more detail | Gram-positive bacteria | NA | NA | Lipid | Synthetic | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | significant role in the pathogenesis of severe inflammatory responses | NA | 21949866 | 2011 | NA |
| PRRID_0926 | Lipoproteins/lipopeptides Click for more detail | Bacteria | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0926 | Lipoproteins/lipopeptides Click for more detail | Bacteria | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | Human | Myeloid cells, T cells, microglia, astrocytes, oligodendrocytes, neurons | NA | O60603.fasta | O60603 | 784 | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21982558 | 2011 | Pubchem Assay |
| PRRID_0927 | Lipoproteins/lipopeptides Click for more detail | Different bacterial pathogens(Bacteria) | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21955443 | 2011 | NA |
| PRRID_0927 | Lipoproteins/lipopeptides Click for more detail | Different bacterial pathogens(Bacteria) | NA | NA | Lipid | Natural | elicit innate immune response | Toll-like receptor 2 (TLR2) | Toll-like receptor (TLR) | NA | NA | NA | NA | NA | NA | plays a fundamental role in pathogen recognition and activation of innate immunity | NA | 21955443 | 2011 | NA |
| PRRID_0936 | monophosphoryl lipid A (MPL) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC | NA | Lipid | Natural | triggers immune responses | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Balb/c mice | Spleen and lung | NA | P58681.fasta | P58681 | 1050 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 21963872 | 2011 | Pubchem Assay |
| PRRID_0936 | monophosphoryl lipid A (MPL) Click for more detail | Gram negative Bacteria (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1OCC2C(C(C(C(O2)O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC | NA | Lipid | Natural | triggers immune responses | Toll-like receptor 7 (TLR7) | Toll-like receptor (TLR) | Balb/c mice | Spleen and lung | NA | P58681.fasta | P58681 | 1050 | plays a fundamental role in pathogen recognition and activation of innate immunity | ELISA | 21963872 | 2011 | Pubchem Assay |